Drosophila melanogaster

131 known processes

Gli (Dmel_CG3903)

Gliotactin

(Aliases: gli,BG:DS09217.3,CG3903,l(2)35Dg,n(2)k09033,l(2)br45,Dmel\CG3903)

Gli biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to light stimulus GO:0009416 124 0.335
Fly
morphogenesis of embryonic epithelium GO:0016331 94 0.300
regulation of growth GO:0040008 233 0.297
intracellular signal transduction GO:0035556 300 0.232
positive regulation of response to stimulus GO:0048584 323 0.179
regulation of multicellular organismal development GO:2000026 414 0.164
post embryonic appendage morphogenesis GO:0035120 385 0.129
regulation of developmental growth GO:0048638 174 0.126
axon development GO:0061564 297 0.115
Fly
regulation of intracellular signal transduction GO:1902531 236 0.114
tissue death GO:0016271 102 0.114
regulation of tube architecture open tracheal system GO:0035152 68 0.112
taxis GO:0042330 304 0.103
Fly
response to radiation GO:0009314 155 0.100
Fly
positive regulation of signal transduction GO:0009967 223 0.096
body morphogenesis GO:0010171 2 0.091
endocytosis GO:0006897 310 0.086
negative regulation of response to stimulus GO:0048585 258 0.078
vesicle mediated transport GO:0016192 381 0.072
growth GO:0040007 359 0.067
death GO:0016265 284 0.067
response to abiotic stimulus GO:0009628 341 0.067
Fly
small molecule metabolic process GO:0044281 305 0.061
Human Mouse Rat Fly
axon guidance GO:0007411 233 0.061
Fly
biological adhesion GO:0022610 138 0.057
respiratory system development GO:0060541 213 0.056
cellular protein modification process GO:0006464 438 0.056
Mouse
developmental growth GO:0048589 280 0.055
dorsal closure GO:0007391 79 0.051
exocrine system development GO:0035272 162 0.051
positive regulation of cell communication GO:0010647 250 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.048
positive regulation of signaling GO:0023056 243 0.047
single organism biosynthetic process GO:0044711 206 0.044
negative regulation of multicellular organismal process GO:0051241 142 0.043
wound healing GO:0042060 75 0.043
salivary gland development GO:0007431 162 0.041
histolysis GO:0007559 102 0.038
protein localization GO:0008104 284 0.038
embryonic pattern specification GO:0009880 174 0.038
response to wounding GO:0009611 94 0.037
cell cell junction assembly GO:0007043 38 0.037
negative regulation of signaling GO:0023057 219 0.036
pigment metabolic process GO:0042440 84 0.036
regulation of anatomical structure morphogenesis GO:0022603 242 0.036
cardiovascular system development GO:0072358 82 0.034
defense response to other organism GO:0098542 225 0.034
Fly
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.034
forebrain development GO:0030900 2 0.033
regulation of cell development GO:0060284 215 0.033
regulation of cellular component biogenesis GO:0044087 201 0.033
phosphorylation GO:0016310 294 0.033
positive regulation of growth GO:0045927 75 0.032
detection of stimulus GO:0051606 156 0.032
single organism behavior GO:0044708 391 0.032
open tracheal system development GO:0007424 204 0.032
proteolysis GO:0006508 192 0.032
regulation of nervous system development GO:0051960 248 0.031
lipid localization GO:0010876 54 0.031
Fly
segmentation GO:0035282 207 0.031
positive regulation of molecular function GO:0044093 136 0.031
developmental programmed cell death GO:0010623 138 0.030
pigmentation GO:0043473 75 0.030
imaginal disc pattern formation GO:0007447 91 0.030
limb morphogenesis GO:0035108 1 0.029
ras protein signal transduction GO:0007265 88 0.029
cellular response to uv GO:0034644 12 0.029
single organism cell adhesion GO:0098602 47 0.029
neurological system process GO:0050877 358 0.029
developmental growth involved in morphogenesis GO:0060560 65 0.029
locomotory behavior GO:0007626 176 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
gland development GO:0048732 191 0.028
tripartite regional subdivision GO:0007351 103 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
cell growth GO:0016049 108 0.026
organonitrogen compound metabolic process GO:1901564 318 0.026
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.026
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
regionalization GO:0003002 416 0.025
pigment metabolic process involved in pigmentation GO:0043474 33 0.025
response to uv GO:0009411 24 0.025
multi multicellular organism process GO:0044706 123 0.025
Fly
regulation of localization GO:0032879 275 0.025
chemotaxis GO:0006935 249 0.025
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.025
spermatogenesis GO:0007283 200 0.024
regulation of molecular function GO:0065009 217 0.024
sensory perception GO:0007600 196 0.024
regulation of protein metabolic process GO:0051246 256 0.024
regulation of response to stress GO:0080134 200 0.024
immune system process GO:0002376 347 0.024
apical junction assembly GO:0043297 32 0.024
embryonic axis specification GO:0000578 107 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
central nervous system development GO:0007417 201 0.023
positive regulation of cell growth GO:0030307 19 0.023
establishment or maintenance of cell polarity GO:0007163 167 0.023
establishment of protein localization GO:0045184 163 0.022
regulation of catalytic activity GO:0050790 185 0.022
regulation of epithelial cell differentiation GO:0030856 4 0.022
developmental pigmentation GO:0048066 68 0.022
regulation of cell projection organization GO:0031344 92 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
cellular macromolecule localization GO:0070727 220 0.022
positive regulation of developmental process GO:0051094 143 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.022
response to lipopolysaccharide GO:0032496 4 0.022
positive regulation of protein metabolic process GO:0051247 128 0.022
chemosensory behavior GO:0007635 106 0.021
dendrite development GO:0016358 204 0.021
anterior posterior pattern specification GO:0009952 136 0.021
carboxylic acid metabolic process GO:0019752 92 0.020
Mouse
head development GO:0060322 135 0.020
cell recognition GO:0008037 102 0.020
response to bacterium GO:0009617 198 0.020
appendage morphogenesis GO:0035107 397 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
rhodopsin metabolic process GO:0046154 10 0.020
cellular amine metabolic process GO:0044106 12 0.020
Fly
cholesterol transport GO:0030301 2 0.020
negative regulation of cellular component organization GO:0051129 108 0.020
cellular response to abiotic stimulus GO:0071214 58 0.020
regulation of cellular response to stress GO:0080135 89 0.019
protein phosphorylation GO:0006468 169 0.019
cell junction assembly GO:0034329 42 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
maternal determination of anterior posterior axis embryo GO:0008358 74 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
axonogenesis GO:0007409 290 0.019
Fly
cell cell junction organization GO:0045216 55 0.019
substrate adhesion dependent cell spreading GO:0034446 2 0.019
sensory perception of chemical stimulus GO:0007606 116 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
muscle organ development GO:0007517 127 0.019
negative regulation of gene expression GO:0010629 387 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
negative regulation of cell communication GO:0010648 223 0.018
regulation of phosphorylation GO:0042325 147 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
centrosome organization GO:0051297 163 0.018
cell death GO:0008219 279 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
response to oxygen containing compound GO:1901700 200 0.018
histone modification GO:0016570 106 0.018
anterior posterior axis specification GO:0009948 109 0.018
chromosome organization GO:0051276 360 0.018
phagocytosis GO:0006909 215 0.018
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
protein maturation GO:0051604 71 0.017
dendrite morphogenesis GO:0048813 199 0.017
gland morphogenesis GO:0022612 145 0.017
protein modification process GO:0036211 438 0.017
Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
glial cell differentiation GO:0010001 35 0.016
glial cell development GO:0021782 27 0.016
positive regulation of developmental growth GO:0048639 62 0.016
single organism cellular localization GO:1902580 180 0.016
androgen metabolic process GO:0008209 1 0.016
regulation of cell morphogenesis GO:0022604 163 0.016
covalent chromatin modification GO:0016569 106 0.016
tissue morphogenesis GO:0048729 297 0.016
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
regulation of neuron differentiation GO:0045664 103 0.016
eye pigment biosynthetic process GO:0006726 32 0.016
heart development GO:0007507 82 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
notch signaling pathway GO:0007219 120 0.016
epidermal growth factor receptor signaling pathway GO:0007173 58 0.015
regulation of protein modification process GO:0031399 112 0.015
regulation of transport GO:0051049 181 0.015
regulation of response to external stimulus GO:0032101 115 0.015
appendage development GO:0048736 401 0.015
lipid metabolic process GO:0006629 121 0.015
Human Mouse Rat
cellular macromolecular complex assembly GO:0034622 153 0.015
regulation of neuron projection development GO:0010975 69 0.015
regulation of cell cycle GO:0051726 291 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
connective tissue development GO:0061448 3 0.015
salivary gland histolysis GO:0035070 88 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
autophagic cell death GO:0048102 83 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
spermatid differentiation GO:0048515 114 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
cellular response to organic substance GO:0071310 132 0.014
regulation of cell growth GO:0001558 43 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
cell fate specification GO:0001708 71 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
meiotic cell cycle process GO:1903046 132 0.014
regulation of embryonic development GO:0045995 68 0.014
eye pigmentation GO:0048069 43 0.014
organelle assembly GO:0070925 198 0.014
oocyte development GO:0048599 124 0.014
axis specification GO:0009798 167 0.014
protein processing GO:0016485 68 0.014
organic substance catabolic process GO:1901575 308 0.013
Human Mouse Fly
developmental maturation GO:0021700 172 0.013
cell motility GO:0048870 251 0.013
regulation of protein localization GO:0032880 76 0.013
meiotic cell cycle GO:0051321 171 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
oxoacid metabolic process GO:0043436 103 0.013
Mouse
microtubule organizing center organization GO:0031023 168 0.013
cell migration GO:0016477 238 0.013
actin filament based process GO:0030029 220 0.013
regulation of cell shape GO:0008360 113 0.013
response to extracellular stimulus GO:0009991 116 0.013
lipid storage GO:0019915 38 0.013
Fly
antimicrobial humoral response GO:0019730 99 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
cellular lipid metabolic process GO:0044255 83 0.012
Mouse Rat
stress activated mapk cascade GO:0051403 52 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
neuron projection guidance GO:0097485 241 0.012
Fly
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
circulatory system development GO:0072359 82 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
macromolecular complex assembly GO:0065003 256 0.012
intracellular mrna localization GO:0008298 66 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
response to nutrient levels GO:0031667 114 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
jak stat cascade GO:0007259 49 0.012
catabolic process GO:0009056 409 0.011
Human Mouse Fly
gliogenesis GO:0042063 80 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
negative regulation of cell death GO:0060548 81 0.011
cell projection assembly GO:0030031 94 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
ion transport GO:0006811 145 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
peptidyl amino acid modification GO:0018193 105 0.011
salivary gland morphogenesis GO:0007435 145 0.011
nucleotide metabolic process GO:0009117 161 0.011
response to external biotic stimulus GO:0043207 293 0.011
Fly
negative regulation of intracellular signal transduction GO:1902532 57 0.011
skin development GO:0043588 65 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
pole plasm mrna localization GO:0019094 49 0.011
response to temperature stimulus GO:0009266 106 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
cell adhesion GO:0007155 136 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
humoral immune response GO:0006959 117 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
vesicle localization GO:0051648 55 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
compound eye morphogenesis GO:0001745 249 0.010
hippo signaling GO:0035329 20 0.010
phagocytosis recognition GO:0006910 1 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
compound eye development GO:0048749 307 0.010
cellular protein localization GO:0034613 160 0.010
regulation of cell differentiation GO:0045595 302 0.010
cellular response to light stimulus GO:0071482 37 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
regulation of neurogenesis GO:0050767 158 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
methylation GO:0032259 47 0.010
negative regulation of growth GO:0045926 84 0.010

Gli disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.031
inherited metabolic disorder DOID:655 0 0.023
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.011