Drosophila melanogaster

78 known processes

ltd (Dmel_CG8024)

lightoid

(Aliases: anon-WO0118547.106,DrabRP1,Rab-RP1,RAB-RP1,Dmel\CG8024,Rab-RP1/CG8024,RabRP1,CG8024,DRABR1,DmRab32,Rab-r1,Rab32/RP1,Rab32)

ltd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigmentation GO:0043473 75 0.643
pigment metabolic process GO:0042440 84 0.641
neurological system process GO:0050877 358 0.638
pigment biosynthetic process GO:0046148 36 0.624
cognition GO:0050890 141 0.565
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.562
developmental pigmentation GO:0048066 68 0.510
secondary metabolic process GO:0019748 75 0.428
ocellus pigment biosynthetic process GO:0008055 19 0.407
eye pigmentation GO:0048069 43 0.376
learning or memory GO:0007611 141 0.350
learning GO:0007612 75 0.293
pigment metabolic process involved in pigmentation GO:0043474 33 0.272
memory GO:0007613 94 0.221
long term memory GO:0007616 62 0.213
single organism biosynthetic process GO:0044711 206 0.202
single organism behavior GO:0044708 391 0.199
secondary metabolite biosynthetic process GO:0044550 24 0.197
ommochrome biosynthetic process GO:0006727 19 0.191
olfactory behavior GO:0042048 97 0.183
eye pigment biosynthetic process GO:0006726 32 0.173
associative learning GO:0008306 65 0.138
small molecule metabolic process GO:0044281 305 0.127
Human
organic substance transport GO:0071702 257 0.125
Human
carboxylic acid metabolic process GO:0019752 92 0.120
macroautophagy GO:0016236 42 0.120
ocellus pigment metabolic process GO:0046158 19 0.119
eye pigment metabolic process GO:0042441 33 0.116
cellular modified amino acid metabolic process GO:0006575 45 0.115
ommochrome metabolic process GO:0046152 19 0.111
ion transport GO:0006811 145 0.109
cellular amino acid metabolic process GO:0006520 61 0.107
oxoacid metabolic process GO:0043436 103 0.106
cellular ketone metabolic process GO:0042180 24 0.099
organic acid metabolic process GO:0006082 103 0.097
vesicle mediated transport GO:0016192 381 0.097
Human
response to other organism GO:0051707 293 0.086
response to external biotic stimulus GO:0043207 293 0.085
response to bacterium GO:0009617 198 0.078
response to biotic stimulus GO:0009607 294 0.074
chemosensory behavior GO:0007635 106 0.074
cellular response to chemical stimulus GO:0070887 199 0.073
death GO:0016265 284 0.072
organonitrogen compound metabolic process GO:1901564 318 0.072
Human
olfactory learning GO:0008355 56 0.070
neuron death GO:0070997 27 0.069
ocellus pigmentation GO:0033060 19 0.065
response to abiotic stimulus GO:0009628 341 0.065
catabolic process GO:0009056 409 0.057
alpha amino acid metabolic process GO:1901605 20 0.055
body morphogenesis GO:0010171 2 0.052
carboxylic acid transport GO:0046942 18 0.052
cellular amine metabolic process GO:0044106 12 0.052
protein modification by small protein conjugation GO:0032446 79 0.050
purine containing compound metabolic process GO:0072521 155 0.050
Human
benzene containing compound metabolic process GO:0042537 3 0.047
retina development in camera type eye GO:0060041 4 0.047
cellular amide metabolic process GO:0043603 80 0.047
peptide metabolic process GO:0006518 80 0.046
cell death GO:0008219 279 0.046
glutathione metabolic process GO:0006749 37 0.046
embryonic morphogenesis GO:0048598 206 0.044
protein complex biogenesis GO:0070271 201 0.044
immune response GO:0006955 246 0.044
regulation of multicellular organismal development GO:2000026 414 0.042
regulation of localization GO:0032879 275 0.042
morphogenesis of an epithelium GO:0002009 276 0.042
single organism intracellular transport GO:1902582 207 0.041
Human
negative regulation of gene expression GO:0010629 387 0.040
endocytosis GO:0006897 310 0.040
regulation of protein metabolic process GO:0051246 256 0.040
protein modification process GO:0036211 438 0.039
protein ubiquitination GO:0016567 70 0.038
autophagy GO:0006914 108 0.037
intracellular transport GO:0046907 228 0.037
Human
tissue morphogenesis GO:0048729 297 0.037
positive regulation of cell motility GO:2000147 3 0.036
lipid metabolic process GO:0006629 121 0.036
humoral immune response GO:0006959 117 0.036
response to wounding GO:0009611 94 0.036
intracellular signal transduction GO:0035556 300 0.036
cellular catabolic process GO:0044248 372 0.036
establishment of localization in cell GO:0051649 402 0.035
Human
programmed cell death GO:0012501 257 0.035
protein complex assembly GO:0006461 200 0.035
appendage development GO:0048736 401 0.035
immune system process GO:0002376 347 0.035
Human
regulation of molecular function GO:0065009 217 0.033
camera type eye development GO:0043010 4 0.033
monocarboxylic acid transport GO:0015718 3 0.032
phagocytosis GO:0006909 215 0.032
embryonic development via the syncytial blastoderm GO:0001700 148 0.032
regulation of cellular protein metabolic process GO:0032268 243 0.032
response to organic cyclic compound GO:0014070 89 0.031
amine metabolic process GO:0009308 12 0.031
protein modification by small protein conjugation or removal GO:0070647 106 0.031
innate immune response GO:0045087 144 0.031
sterol homeostasis GO:0055092 4 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
forebrain development GO:0030900 2 0.029
macromolecular complex assembly GO:0065003 256 0.029
response to organic substance GO:0010033 284 0.028
single organism catabolic process GO:0044712 228 0.028
Human
positive regulation of cell migration GO:0030335 2 0.028
protein localization GO:0008104 284 0.028
Human
adult behavior GO:0030534 137 0.027
locomotory behavior GO:0007626 176 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
membrane organization GO:0061024 112 0.027
Human
defense response to bacterium GO:0042742 178 0.027
sensory organ morphogenesis GO:0090596 260 0.027
aromatic amino acid family metabolic process GO:0009072 3 0.027
epithelial cell differentiation GO:0030855 322 0.026
cellular response to nutrient levels GO:0031669 62 0.026
cellular response to starvation GO:0009267 61 0.026
establishment of protein localization GO:0045184 163 0.026
Human
response to alcohol GO:0097305 95 0.026
cell projection assembly GO:0030031 94 0.026
rna localization GO:0006403 115 0.026
response to extracellular stimulus GO:0009991 116 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
nitrogen compound transport GO:0071705 85 0.025
regulation of response to external stimulus GO:0032101 115 0.025
epidermis development GO:0008544 65 0.024
defense response GO:0006952 300 0.024
response to lipopolysaccharide GO:0032496 4 0.024
enzyme linked receptor protein signaling pathway GO:0007167 179 0.024
axis specification GO:0009798 167 0.024
urogenital system development GO:0001655 72 0.024
central nervous system development GO:0007417 201 0.023
gland development GO:0048732 191 0.023
hematopoietic progenitor cell differentiation GO:0002244 1 0.023
response to lipid GO:0033993 38 0.023
appendage morphogenesis GO:0035107 397 0.023
cellular response to extracellular stimulus GO:0031668 64 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
salivary gland development GO:0007431 162 0.023
cellularization GO:0007349 90 0.022
defense response to other organism GO:0098542 225 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
compound eye pigmentation GO:0048072 17 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
cellular response to external stimulus GO:0071496 66 0.022
positive regulation of response to external stimulus GO:0032103 44 0.022
organic substance catabolic process GO:1901575 308 0.022
Human
renal system development GO:0072001 72 0.022
cell migration GO:0016477 238 0.022
response to oxygen containing compound GO:1901700 200 0.021
cellular lipid metabolic process GO:0044255 83 0.021
taxis GO:0042330 304 0.021
cellular protein modification process GO:0006464 438 0.021
wing disc morphogenesis GO:0007472 344 0.021
cellular homeostasis GO:0019725 80 0.021
Human
signal transduction by phosphorylation GO:0023014 107 0.021
sulfur compound metabolic process GO:0006790 59 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
ribonucleoside metabolic process GO:0009119 127 0.020
Human
cellular protein complex assembly GO:0043623 71 0.020
cell proliferation GO:0008283 299 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
salivary gland histolysis GO:0035070 88 0.020
sensory perception GO:0007600 196 0.020
regulation of transport GO:0051049 181 0.020
Human
nucleoside phosphate metabolic process GO:0006753 162 0.019
Human
respiratory system development GO:0060541 213 0.019
tube morphogenesis GO:0035239 191 0.019
embryonic axis specification GO:0000578 107 0.019
sensory perception of sound GO:0007605 56 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
Human
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.019
regulation of protein transport GO:0051223 57 0.019
Human
organic anion transport GO:0015711 28 0.018
multi organism behavior GO:0051705 175 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
positive regulation of signaling GO:0023056 243 0.018
phosphorylation GO:0016310 294 0.018
positive regulation of cell communication GO:0010647 250 0.018
cytoplasmic transport GO:0016482 130 0.018
Human
positive regulation of cell death GO:0010942 69 0.018
regionalization GO:0003002 416 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
salivary gland cell autophagic cell death GO:0035071 83 0.018
regulation of immune system process GO:0002682 176 0.018
actin cytoskeleton organization GO:0030036 206 0.018
exocrine system development GO:0035272 162 0.018
organic acid transport GO:0015849 18 0.018
regulation of catalytic activity GO:0050790 185 0.018
regulation of cell proliferation GO:0042127 163 0.018
vitamin metabolic process GO:0006766 2 0.018
protein maturation GO:0051604 71 0.017
hemopoiesis GO:0030097 46 0.017
response to nutrient levels GO:0031667 114 0.017
anion transport GO:0006820 41 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
Human
dorsal ventral pattern formation GO:0009953 133 0.017
actin filament based process GO:0030029 220 0.017
transmembrane transport GO:0055085 139 0.017
regulation of protein localization GO:0032880 76 0.017
Human
cellular response to organic substance GO:0071310 132 0.017
organophosphate metabolic process GO:0019637 195 0.017
Human
maintenance of location GO:0051235 73 0.016
response to nitrogen compound GO:1901698 90 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
positive regulation of signal transduction GO:0009967 223 0.016
protein transport GO:0015031 155 0.016
Human
cation transport GO:0006812 110 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
Human
response to sterol GO:0036314 34 0.016
short term memory GO:0007614 19 0.016
regulation of protein modification process GO:0031399 112 0.016
ethanolamine containing compound metabolic process GO:0042439 4 0.016
homeostatic process GO:0042592 199 0.016
Human
reproductive behavior GO:0019098 122 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
polyol biosynthetic process GO:0046173 3 0.016
mesenchymal cell development GO:0014031 1 0.016
regulation of catabolic process GO:0009894 170 0.016
regulation of cell death GO:0010941 173 0.016
regulation of apoptotic process GO:0042981 130 0.016
immune system development GO:0002520 57 0.016
aging GO:0007568 143 0.015
response to endogenous stimulus GO:0009719 119 0.015
blastoderm segmentation GO:0007350 159 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
tissue death GO:0016271 102 0.015
regulation of multi organism process GO:0043900 131 0.015
chemical homeostasis GO:0048878 92 0.015
Human
positive regulation of molecular function GO:0044093 136 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
ras protein signal transduction GO:0007265 88 0.015
brain development GO:0007420 120 0.015
intracellular protein transport GO:0006886 104 0.015
Human
response to monosaccharide GO:0034284 4 0.015
regulation of vesicle mediated transport GO:0060627 59 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
Human
regulation of intracellular signal transduction GO:1902531 236 0.014
response to starvation GO:0042594 97 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of response to stress GO:0080134 200 0.014
response to organophosphorus GO:0046683 2 0.014
anterior posterior pattern specification GO:0009952 136 0.014
aromatic compound catabolic process GO:0019439 166 0.014
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
stem cell development GO:0048864 79 0.014
response to organonitrogen compound GO:0010243 75 0.014
cytoskeleton dependent intracellular transport GO:0030705 44 0.014
nucleotide metabolic process GO:0009117 161 0.013
Human
developmental programmed cell death GO:0010623 138 0.013
apoptotic process GO:0006915 159 0.013
regulation of defense response GO:0031347 102 0.013
establishment of rna localization GO:0051236 47 0.013
eye pigment granule organization GO:0008057 12 0.013
cell maturation GO:0048469 144 0.013
telencephalon development GO:0021537 2 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
regulation of programmed cell death GO:0043067 152 0.013
positive regulation of macroautophagy GO:0016239 8 0.013
mapk cascade GO:0000165 107 0.013
chemotaxis GO:0006935 249 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
dendrite morphogenesis GO:0048813 199 0.013
regulation of growth GO:0040008 233 0.013
lipid biosynthetic process GO:0008610 46 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
ameboidal type cell migration GO:0001667 151 0.013
salivary gland morphogenesis GO:0007435 145 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.013
negative regulation of defense response GO:0031348 35 0.013
anterior posterior axis specification GO:0009948 109 0.013
limb development GO:0060173 1 0.013
gliogenesis GO:0042063 80 0.013
chromosome organization GO:0051276 360 0.013
l amino acid import GO:0043092 2 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
negative regulation of response to stimulus GO:0048585 258 0.012
multicellular organismal aging GO:0010259 140 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
axon guidance GO:0007411 233 0.012
cellular pigmentation GO:0033059 12 0.012
amide biosynthetic process GO:0043604 42 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
molting cycle chitin based cuticle GO:0007591 56 0.012
protein phosphorylation GO:0006468 169 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
response to ecdysone GO:0035075 34 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
regulation of macroautophagy GO:0016241 15 0.012
regulation of anatomical structure size GO:0090066 163 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
cation transmembrane transport GO:0098655 88 0.012
ion transmembrane transport GO:0034220 122 0.012
steroid biosynthetic process GO:0006694 16 0.012
microtubule organizing center organization GO:0031023 168 0.012
regulation of immune response GO:0050776 118 0.012
cellular response to monosaccharide stimulus GO:0071326 2 0.012
positive regulation of immune system process GO:0002684 68 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
cilium assembly GO:0042384 38 0.012
cellular chemical homeostasis GO:0055082 40 0.012
Human
notch signaling pathway GO:0007219 120 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
neuron projection guidance GO:0097485 241 0.012
chorion containing eggshell formation GO:0007304 105 0.012
cellular response to hexose stimulus GO:0071331 1 0.012
response to light stimulus GO:0009416 124 0.012
notch receptor processing GO:0007220 13 0.012
nucleobase containing compound transport GO:0015931 56 0.012
histolysis GO:0007559 102 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
hair cell differentiation GO:0035315 47 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
Human
organophosphate biosynthetic process GO:0090407 46 0.011
peripheral nervous system development GO:0007422 52 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.011
embryonic pattern specification GO:0009880 174 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
cell recognition GO:0008037 102 0.011
peptide biosynthetic process GO:0043043 42 0.011
protein secretion GO:0009306 45 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
steroid metabolic process GO:0008202 20 0.011
wnt signaling pathway GO:0016055 98 0.011
negative regulation of gene silencing by rna GO:0060967 9 0.011
cilium morphogenesis GO:0060271 39 0.011
cell motility GO:0048870 251 0.011
response to temperature stimulus GO:0009266 106 0.011
epithelial cell migration GO:0010631 148 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
immune effector process GO:0002252 98 0.011
oxidation reduction process GO:0055114 123 0.011
developmental maturation GO:0021700 172 0.011
Human
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
secretion GO:0046903 109 0.011
proteolysis GO:0006508 192 0.011
regulation of locomotion GO:0040012 42 0.011
determination of adult lifespan GO:0008340 137 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of response to extracellular stimulus GO:0032104 18 0.011
tube development GO:0035295 244 0.011
spindle organization GO:0007051 253 0.011
digestive tract development GO:0048565 149 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
cell aging GO:0007569 2 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
Human
wound healing GO:0042060 75 0.011
cellular response to organic cyclic compound GO:0071407 32 0.011
negative regulation of immune system process GO:0002683 50 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
Human
mitochondrion organization GO:0007005 65 0.011
secretion by cell GO:0032940 101 0.011
eggshell chorion assembly GO:0007306 66 0.011
hindbrain development GO:0030902 2 0.011
response to ketone GO:1901654 34 0.011
small molecule biosynthetic process GO:0044283 37 0.011
response to decreased oxygen levels GO:0036293 58 0.011
divalent inorganic cation homeostasis GO:0072507 29 0.011
positive regulation of developmental process GO:0051094 143 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
cell junction organization GO:0034330 57 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
regulation of response to nutrient levels GO:0032107 18 0.010
skin development GO:0043588 65 0.010
kidney development GO:0001822 3 0.010
regulation of cellular localization GO:0060341 136 0.010
Human
regulation of developmental pigmentation GO:0048070 24 0.010
positive regulation of gene expression GO:0010628 290 0.010
synaptic transmission GO:0007268 288 0.010
pattern recognition receptor signaling pathway GO:0002221 2 0.010
heterocycle catabolic process GO:0046700 166 0.010
Human
response to glucose GO:0009749 2 0.010
axon cargo transport GO:0008088 29 0.010
eye development GO:0001654 323 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
response to radiation GO:0009314 155 0.010

ltd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
urinary system disease DOID:18 0 0.020
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
disease of metabolism DOID:0014667 0 0.018
cardiovascular system disease DOID:1287 0 0.015
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.012