Drosophila melanogaster

9 known processes

rpk (Dmel_CG1058)

ripped pocket

(Aliases: dGNaC1,RPK,Dmel\CG1058,CG1058,GNaC1)

rpk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of salty taste GO:0050914 3 0.856
Fly
sensory perception GO:0007600 196 0.731
inter male aggressive behavior GO:0002121 60 0.479
Fly
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.471
Fly
single organism behavior GO:0044708 391 0.318
Fly
detection of stimulus GO:0051606 156 0.246
Fly
sensory perception of mechanical stimulus GO:0050954 72 0.202
aggressive behavior GO:0002118 63 0.195
Fly
behavioral response to pain GO:0048266 3 0.191
Fly
neurological system process GO:0050877 358 0.187
sensory perception of touch GO:0050975 11 0.170
response to abiotic stimulus GO:0009628 341 0.152
Rat Fly
epiboly GO:0090504 2 0.145
Rat
response to pain GO:0048265 3 0.144
Fly
epiboly involved in wound healing GO:0090505 2 0.135
Rat
male courtship behavior GO:0008049 63 0.125
Fly
cation homeostasis GO:0055080 51 0.123
Human
respiratory system development GO:0060541 213 0.120
Fly
transmembrane transport GO:0055085 139 0.111
Human Rat Fly
cell migration GO:0016477 238 0.109
Rat
response to pheromone GO:0019236 19 0.104
Fly
feeding behavior GO:0007631 50 0.095
Fly
drinking behavior GO:0042756 2 0.082
Fly
regionalization GO:0003002 416 0.075
nuclear division GO:0000280 332 0.074
salt aversion GO:0035199 3 0.073
Fly
sensory perception of pain GO:0019233 4 0.069
Fly
ion transmembrane transport GO:0034220 122 0.069
Human Rat Fly
courtship behavior GO:0007619 68 0.069
Fly
response to temperature stimulus GO:0009266 106 0.067
Fly
negative regulation of response to stimulus GO:0048585 258 0.065
Fly
inorganic ion transmembrane transport GO:0098660 73 0.063
Human Rat Fly
metal ion homeostasis GO:0055065 44 0.062
Human
locomotory behavior GO:0007626 176 0.057
Fly
regulation of behavior GO:0050795 75 0.056
Fly
cellular response to abiotic stimulus GO:0071214 58 0.055
Fly
synaptic transmission GO:0007268 288 0.055
Fly
mating GO:0007618 120 0.054
Fly
homeostatic process GO:0042592 199 0.051
Human
gene silencing by rna GO:0031047 57 0.051
localization of cell GO:0051674 257 0.048
Rat
mechanosensory behavior GO:0007638 12 0.046
Fly
water homeostasis GO:0030104 3 0.045
Human
wound healing spreading of epidermal cells GO:0035313 1 0.042
Rat
cognition GO:0050890 141 0.041
gene silencing GO:0016458 138 0.041
regulation of synapse structure and activity GO:0050803 128 0.039
Fly
positive regulation of response to stimulus GO:0048584 323 0.039
cell division GO:0051301 248 0.036
inorganic cation transmembrane transport GO:0098662 61 0.036
Human Rat Fly
response to mechanical stimulus GO:0009612 28 0.034
Fly
mitotic nuclear division GO:0007067 213 0.034
larval locomotory behavior GO:0008345 27 0.034
Fly
sodium ion transport GO:0006814 22 0.033
Human Rat Fly
metal ion transport GO:0030001 74 0.033
Human Rat Fly
cellular response to water stimulus GO:0071462 2 0.033
Fly
taxis GO:0042330 304 0.033
olfactory learning GO:0008355 56 0.032
appendage development GO:0048736 401 0.032
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.031
protein complex biogenesis GO:0070271 201 0.031
negative regulation of gene expression GO:0010629 387 0.031
olfactory behavior GO:0042048 97 0.031
larval behavior GO:0030537 42 0.031
Fly
response to decreased oxygen levels GO:0036293 58 0.030
Rat
detection of stimulus involved in sensory perception GO:0050906 92 0.030
Fly
multi organism reproductive behavior GO:0044705 121 0.030
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
chemical homeostasis GO:0048878 92 0.028
Human
cell proliferation GO:0008283 299 0.028
organelle fission GO:0048285 340 0.027
regulation of localization GO:0032879 275 0.027
Rat
cation transport GO:0006812 110 0.027
Human Rat Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.027
body morphogenesis GO:0010171 2 0.027
protein localization GO:0008104 284 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
heterocycle catabolic process GO:0046700 166 0.026
organelle assembly GO:0070925 198 0.026
behavioral response to ethanol GO:0048149 49 0.025
detection of abiotic stimulus GO:0009582 66 0.025
Fly
mating behavior GO:0007617 106 0.025
Fly
negative regulation of biosynthetic process GO:0009890 277 0.025
appendage morphogenesis GO:0035107 397 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
male mating behavior GO:0060179 70 0.023
Fly
endocytosis GO:0006897 310 0.023
single organism catabolic process GO:0044712 228 0.023
organic substance catabolic process GO:1901575 308 0.023
positive regulation of rna metabolic process GO:0051254 271 0.022
response to radiation GO:0009314 155 0.022
response to biotic stimulus GO:0009607 294 0.022
regulation of cell cycle GO:0051726 291 0.021
cell cycle phase transition GO:0044770 140 0.021
ion homeostasis GO:0050801 55 0.021
Human
segmentation GO:0035282 207 0.021
meiotic cell cycle GO:0051321 171 0.021
morphogenesis of an epithelium GO:0002009 276 0.021
Rat
response to external biotic stimulus GO:0043207 293 0.021
macromolecular complex assembly GO:0065003 256 0.020
positive regulation of signal transduction GO:0009967 223 0.020
fluid transport GO:0042044 19 0.020
Fly
regulation of ion transport GO:0043269 39 0.020
Rat
regulation of sodium ion transport GO:0002028 5 0.020
Rat
associative learning GO:0008306 65 0.020
axis specification GO:0009798 167 0.020
positive regulation of gene expression GO:0010628 290 0.020
response to alcohol GO:0097305 95 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
ion transport GO:0006811 145 0.020
Human Rat Fly
cellular macromolecule localization GO:0070727 220 0.019
wing disc morphogenesis GO:0007472 344 0.019
meiotic nuclear division GO:0007126 151 0.019
regulation of synaptic transmission GO:0050804 69 0.019
Fly
cell maturation GO:0048469 144 0.019
axon development GO:0061564 297 0.019
negative regulation of signaling GO:0023057 219 0.019
protein complex assembly GO:0006461 200 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
membrane depolarization GO:0051899 4 0.019
maintenance of protein location GO:0045185 28 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
negative regulation of signal transduction GO:0009968 206 0.018
steroid catabolic process GO:0006706 1 0.018
organic substance transport GO:0071702 257 0.018
response to oxygen containing compound GO:1901700 200 0.018
Fly
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
anterior posterior axis specification embryo GO:0008595 103 0.018
single organism cellular localization GO:1902580 180 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
blastoderm segmentation GO:0007350 159 0.018
phagocytosis GO:0006909 215 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
Fly
regulation of embryonic development GO:0045995 68 0.017
positive regulation of signaling GO:0023056 243 0.017
gland development GO:0048732 191 0.017
response to ethanol GO:0045471 59 0.017
immune system process GO:0002376 347 0.017
intracellular transport GO:0046907 228 0.017
dendrite morphogenesis GO:0048813 199 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
neural precursor cell proliferation GO:0061351 75 0.017
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
cellular catabolic process GO:0044248 372 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
dna damage checkpoint GO:0000077 78 0.016
posttranscriptional gene silencing GO:0016441 46 0.016
embryonic pattern specification GO:0009880 174 0.016
death GO:0016265 284 0.016
tissue morphogenesis GO:0048729 297 0.016
Rat
female meiotic division GO:0007143 70 0.016
dendrite development GO:0016358 204 0.016
positive regulation of cell communication GO:0010647 250 0.016
vesicle mediated transport GO:0016192 381 0.016
posttranscriptional gene silencing by rna GO:0035194 45 0.016
cell death GO:0008219 279 0.015
catabolic process GO:0009056 409 0.015
imaginal disc pattern formation GO:0007447 91 0.015
response to organophosphorus GO:0046683 2 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
regulation of transport GO:0051049 181 0.015
Rat
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
learning GO:0007612 75 0.015
meiotic cell cycle process GO:1903046 132 0.015
regulation of nervous system development GO:0051960 248 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
Fly
aromatic compound catabolic process GO:0019439 166 0.015
stem cell differentiation GO:0048863 117 0.015
regulation of gene expression epigenetic GO:0040029 128 0.014
embryonic axis specification GO:0000578 107 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
salivary gland morphogenesis GO:0007435 145 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
epithelial cell differentiation GO:0030855 322 0.014
small molecule metabolic process GO:0044281 305 0.014
chromosome segregation GO:0007059 157 0.014
regulation of cell differentiation GO:0045595 302 0.014
chemotaxis GO:0006935 249 0.014
digestive tract development GO:0048565 149 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
chromosome organization GO:0051276 360 0.014
learning or memory GO:0007611 141 0.014
actin cytoskeleton organization GO:0030036 206 0.013
kidney development GO:0001822 3 0.013
response to light stimulus GO:0009416 124 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.013
Fly
organonitrogen compound metabolic process GO:1901564 318 0.013
monovalent inorganic cation transport GO:0015672 40 0.013
Human Rat Fly
pole cell development GO:0007277 26 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
tube morphogenesis GO:0035239 191 0.013
xenobiotic catabolic process GO:0042178 1 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
regulation of molecular function GO:0065009 217 0.013
spindle organization GO:0007051 253 0.013
regulation of cell death GO:0010941 173 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
ovarian follicle cell development GO:0030707 248 0.013
hormone catabolic process GO:0042447 3 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
response to organic substance GO:0010033 284 0.013
Fly
actin filament based process GO:0030029 220 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
response to wounding GO:0009611 94 0.012
Rat
detection of mechanical stimulus GO:0050982 6 0.012
Fly
wound healing spreading of cells GO:0044319 2 0.012
Rat
regulation of synaptic activity GO:0060025 9 0.012
Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
central nervous system development GO:0007417 201 0.012
epithelial cell development GO:0002064 274 0.012
actin filament organization GO:0007015 126 0.012
nucleoside catabolic process GO:0009164 112 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
response to lipopolysaccharide GO:0032496 4 0.012
regulation of catabolic process GO:0009894 170 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
telencephalon development GO:0021537 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 39 0.012
developmental maturation GO:0021700 172 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
dna integrity checkpoint GO:0031570 81 0.012
regulation of circadian rhythm GO:0042752 49 0.012
notch signaling pathway GO:0007219 120 0.012
chemosensory behavior GO:0007635 106 0.012
maintenance of location GO:0051235 73 0.012
eggshell formation GO:0030703 105 0.012
lateral inhibition GO:0046331 206 0.012
sensory perception of chemical stimulus GO:0007606 116 0.012
Fly
purine ribonucleoside catabolic process GO:0046130 112 0.012
cell motility GO:0048870 251 0.012
Rat
ribonucleotide metabolic process GO:0009259 145 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
digestive tract morphogenesis GO:0048546 127 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
mushroom body development GO:0016319 70 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
asymmetric stem cell division GO:0098722 49 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
rna processing GO:0006396 147 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
mrna processing GO:0006397 104 0.011
organic acid metabolic process GO:0006082 103 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
maintenance of location in cell GO:0051651 28 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
single organism intracellular transport GO:1902582 207 0.011
rhythmic process GO:0048511 106 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
histolysis GO:0007559 102 0.011
tripartite regional subdivision GO:0007351 103 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
anterior posterior axis specification GO:0009948 109 0.010
camera type eye development GO:0043010 4 0.010
response to monosaccharide GO:0034284 4 0.010
organophosphate metabolic process GO:0019637 195 0.010
nucleotide metabolic process GO:0009117 161 0.010
organophosphate catabolic process GO:0046434 112 0.010
cation transmembrane transport GO:0098655 88 0.010
Human Rat Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
cranial nerve development GO:0021545 1 0.010
defense response to bacterium GO:0042742 178 0.010
monovalent inorganic cation homeostasis GO:0055067 7 0.010
Human
anterior posterior pattern specification GO:0009952 136 0.010
gland morphogenesis GO:0022612 145 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
ras protein signal transduction GO:0007265 88 0.010
developmental programmed cell death GO:0010623 138 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
regulation of response to external stimulus GO:0032101 115 0.010

rpk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.791
Human
lower respiratory tract disease DOID:0050161 0 0.791
Human
bronchial disease DOID:1176 0 0.791
Human
disease of anatomical entity DOID:7 0 0.791
Human
bronchiectasis DOID:9563 0 0.205
Human
renal tubular transport disease DOID:447 0 0.115
Human
kidney disease DOID:557 0 0.115
Human
urinary system disease DOID:18 0 0.115
Human
liddle syndrome DOID:0050477 0 0.051
Human
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
cardiovascular system disease DOID:1287 0 0.010