Drosophila melanogaster

57 known processes

TfIIB (Dmel_CG5193)

Transcription factor IIB

(Aliases: CG5193,dTfIIB,Dmel\CG5193,Tfiib,TFIIB,dTFIIB,dmTFIIB)

TfIIB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome cycle GO:0007098 137 0.486
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.396
positive regulation of macromolecule metabolic process GO:0010604 405 0.374
eye morphogenesis GO:0048592 260 0.287
intracellular signal transduction GO:0035556 300 0.285
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.276
establishment of localization in cell GO:0051649 402 0.264
cell migration GO:0016477 238 0.255
regulation of cell cycle process GO:0010564 181 0.251
cell division GO:0051301 248 0.240
negative regulation of gene expression GO:0010629 387 0.221
positive regulation of cellular biosynthetic process GO:0031328 316 0.211
regulation of intracellular signal transduction GO:1902531 236 0.206
posttranscriptional regulation of gene expression GO:0010608 145 0.202
vesicle mediated transport GO:0016192 381 0.196
intracellular transport GO:0046907 228 0.177
cellular catabolic process GO:0044248 372 0.175
catabolic process GO:0009056 409 0.159
regulation of catabolic process GO:0009894 170 0.158
positive regulation of nucleic acid templated transcription GO:1903508 266 0.156
organic substance catabolic process GO:1901575 308 0.154
actin cytoskeleton organization GO:0030036 206 0.141
endocytosis GO:0006897 310 0.138
regulation of organelle organization GO:0033043 196 0.137
single organism intracellular transport GO:1902582 207 0.136
regulation of cell cycle GO:0051726 291 0.135
nuclear division GO:0000280 332 0.131
positive regulation of biosynthetic process GO:0009891 316 0.131
protein complex biogenesis GO:0070271 201 0.128
regulation of localization GO:0032879 275 0.123
nucleobase containing compound catabolic process GO:0034655 165 0.123
single organism catabolic process GO:0044712 228 0.115
chromosome organization GO:0051276 360 0.114
heterocycle catabolic process GO:0046700 166 0.114
establishment of protein localization GO:0045184 163 0.114
regulation of cellular protein metabolic process GO:0032268 243 0.111
rna processing GO:0006396 147 0.106
death GO:0016265 284 0.100
regulation of multicellular organismal development GO:2000026 414 0.098
protein localization GO:0008104 284 0.097
spindle organization GO:0007051 253 0.096
establishment or maintenance of cell polarity GO:0007163 167 0.094
apoptotic process GO:0006915 159 0.094
macromolecular complex assembly GO:0065003 256 0.094
regulation of cell differentiation GO:0045595 302 0.093
negative regulation of cellular metabolic process GO:0031324 382 0.092
organic substance transport GO:0071702 257 0.091
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.090
stem cell differentiation GO:0048863 117 0.088
positive regulation of rna metabolic process GO:0051254 271 0.088
cell death GO:0008219 279 0.087
regulation of cellular component biogenesis GO:0044087 201 0.087
cell motility GO:0048870 251 0.086
positive regulation of gene expression GO:0010628 290 0.084
positive regulation of transcription dna templated GO:0045893 266 0.084
positive regulation of rna biosynthetic process GO:1902680 266 0.083
ras protein signal transduction GO:0007265 88 0.082
actin filament based process GO:0030029 220 0.078
glycosyl compound catabolic process GO:1901658 112 0.077
regulation of cell death GO:0010941 173 0.076
localization of cell GO:0051674 257 0.074
single organism cellular localization GO:1902580 180 0.070
response to organic substance GO:0010033 284 0.070
microtubule organizing center organization GO:0031023 168 0.069
protein complex assembly GO:0006461 200 0.069
cellular response to dna damage stimulus GO:0006974 223 0.068
cytoplasmic transport GO:0016482 130 0.068
cellular nitrogen compound catabolic process GO:0044270 165 0.067
negative regulation of rna metabolic process GO:0051253 251 0.065
regulation of cellular catabolic process GO:0031329 157 0.064
embryo development ending in birth or egg hatching GO:0009792 152 0.064
Worm
chromatin organization GO:0006325 207 0.063
dna repair GO:0006281 54 0.063
cellular protein localization GO:0034613 160 0.061
eye development GO:0001654 323 0.060
aromatic compound catabolic process GO:0019439 166 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.060
transcription from rna polymerase ii promoter GO:0006366 368 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.056
rna splicing GO:0008380 83 0.056
protein transport GO:0015031 155 0.055
intracellular protein transport GO:0006886 104 0.054
mrna splicing via spliceosome GO:0000398 73 0.053
cellular macromolecule catabolic process GO:0044265 136 0.053
cellular macromolecule localization GO:0070727 220 0.053
regulation of protein metabolic process GO:0051246 256 0.052
regulation of gene expression epigenetic GO:0040029 128 0.052
purine nucleoside triphosphate catabolic process GO:0009146 108 0.052
organic cyclic compound catabolic process GO:1901361 168 0.052
regulation of programmed cell death GO:0043067 152 0.051
negative regulation of biosynthetic process GO:0009890 277 0.050
nucleocytoplasmic transport GO:0006913 72 0.050
regulation of cellular localization GO:0060341 136 0.049
cellular macromolecular complex assembly GO:0034622 153 0.048
nucleoside triphosphate metabolic process GO:0009141 120 0.048
immune system process GO:0002376 347 0.048
macromolecule catabolic process GO:0009057 161 0.047
stem cell maintenance GO:0019827 67 0.047
compound eye development GO:0048749 307 0.046
immune response GO:0006955 246 0.046
negative regulation of cell differentiation GO:0045596 143 0.046
morphogenesis of an epithelium GO:0002009 276 0.045
regulation of transport GO:0051049 181 0.045
sex differentiation GO:0007548 81 0.045
protein modification process GO:0036211 438 0.044
regulation of apoptotic process GO:0042981 130 0.043
organophosphate catabolic process GO:0046434 112 0.043
negative regulation of rna biosynthetic process GO:1902679 240 0.043
sensory organ morphogenesis GO:0090596 260 0.042
hematopoietic progenitor cell differentiation GO:0002244 1 0.041
purine containing compound metabolic process GO:0072521 155 0.041
carbohydrate derivative metabolic process GO:1901135 217 0.041
ribonucleoside triphosphate catabolic process GO:0009203 108 0.041
posttranscriptional gene silencing GO:0016441 46 0.040
hematopoietic or lymphoid organ development GO:0048534 57 0.039
nucleoside triphosphate catabolic process GO:0009143 108 0.039
regulation of nucleotide metabolic process GO:0006140 62 0.038
negative regulation of developmental process GO:0051093 201 0.037
rna splicing via transesterification reactions GO:0000375 73 0.037
guanosine containing compound metabolic process GO:1901068 74 0.036
protein localization to organelle GO:0033365 82 0.036
posttranscriptional gene silencing by rna GO:0035194 45 0.036
striated muscle cell differentiation GO:0051146 90 0.036
ribonucleoside triphosphate metabolic process GO:0009199 119 0.035
purine ribonucleotide catabolic process GO:0009154 109 0.034
cell proliferation GO:0008283 299 0.034
regulation of cell proliferation GO:0042127 163 0.034
mrna metabolic process GO:0016071 124 0.033
mrna processing GO:0006397 104 0.033
salivary gland development GO:0007431 162 0.033
regulation of meiosis GO:0040020 3 0.032
ribonucleoside metabolic process GO:0009119 127 0.032
embryonic morphogenesis GO:0048598 206 0.032
purine ribonucleoside catabolic process GO:0046130 112 0.032
nucleoside metabolic process GO:0009116 127 0.032
purine ribonucleotide metabolic process GO:0009150 145 0.032
camera type eye development GO:0043010 4 0.032
negative regulation of nucleic acid templated transcription GO:1903507 240 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
phagocytosis GO:0006909 215 0.031
regulation of dna metabolic process GO:0051052 34 0.031
programmed cell death GO:0012501 257 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.030
actomyosin structure organization GO:0031032 56 0.030
cellular protein modification process GO:0006464 438 0.030
regulation of catalytic activity GO:0050790 185 0.030
purine containing compound catabolic process GO:0072523 112 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.029
gland development GO:0048732 191 0.029
protein catabolic process GO:0030163 101 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
nucleoside phosphate catabolic process GO:1901292 110 0.028
single organism membrane organization GO:0044802 93 0.028
adult behavior GO:0030534 137 0.028
chromosome segregation GO:0007059 157 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
nucleotide catabolic process GO:0009166 109 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
cytoskeleton dependent cytokinesis GO:0061640 81 0.027
ribonucleoside catabolic process GO:0042454 112 0.027
centrosome duplication GO:0051298 121 0.026
regulation of immune system process GO:0002682 176 0.026
larval development GO:0002164 104 0.026
regulation of intracellular transport GO:0032386 64 0.025
muscle structure development GO:0061061 224 0.025
nuclear transport GO:0051169 72 0.025
meiotic cell cycle GO:0051321 171 0.025
ion transport GO:0006811 145 0.025
protein targeting GO:0006605 64 0.025
compound eye morphogenesis GO:0001745 249 0.025
small molecule metabolic process GO:0044281 305 0.025
positive regulation of molecular function GO:0044093 136 0.025
purine nucleoside triphosphate metabolic process GO:0009144 119 0.025
response to abiotic stimulus GO:0009628 341 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
meiotic nuclear division GO:0007126 151 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
histone modification GO:0016570 106 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
centrosome organization GO:0051297 163 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.024
neuromuscular junction development GO:0007528 149 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
developmental growth GO:0048589 280 0.023
muscle cell differentiation GO:0042692 103 0.023
mitotic spindle organization GO:0007052 220 0.023
dna metabolic process GO:0006259 227 0.022
dendrite development GO:0016358 204 0.022
reproductive structure development GO:0048608 74 0.022
neuron projection guidance GO:0097485 241 0.022
intermediate filament cytoskeleton organization GO:0045104 1 0.021
nucleosome assembly GO:0006334 35 0.021
response to alcohol GO:0097305 95 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
proteolysis GO:0006508 192 0.021
nucleoside catabolic process GO:0009164 112 0.020
regulation of hydrolase activity GO:0051336 97 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
cellular protein catabolic process GO:0044257 83 0.020
endomembrane system organization GO:0010256 119 0.020
guanosine containing compound catabolic process GO:1901069 74 0.019
stem cell development GO:0048864 79 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
synaptic transmission GO:0007268 288 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
regulation of peptidase activity GO:0052547 39 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
negative regulation of programmed cell death GO:0043069 72 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
regulation of cell division GO:0051302 72 0.018
regulation of protein catabolic process GO:0042176 55 0.018
regulation of cell cycle phase transition GO:1901987 130 0.018
positive regulation of catalytic activity GO:0043085 118 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
regulation of proteolysis GO:0030162 87 0.017
carbohydrate metabolic process GO:0005975 82 0.017
regulation of purine nucleotide metabolic process GO:1900542 62 0.017
immune system development GO:0002520 57 0.017
regulation of response to stress GO:0080134 200 0.017
membrane organization GO:0061024 112 0.017
gene silencing by rna GO:0031047 57 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
forebrain development GO:0030900 2 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.016
dna replication GO:0006260 48 0.016
regulation of gtpase activity GO:0043087 44 0.016
response to organic cyclic compound GO:0014070 89 0.016
regulation of ruffle assembly GO:1900027 1 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
nucleotide metabolic process GO:0009117 161 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
ncrna metabolic process GO:0034660 43 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
multi organism behavior GO:0051705 175 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
negative regulation of apoptotic process GO:0043066 63 0.016
regulation of protein localization GO:0032880 76 0.016
regulation of rna splicing GO:0043484 69 0.015
organophosphate metabolic process GO:0019637 195 0.015
regulation of nervous system development GO:0051960 248 0.015
regulation of cellular protein catabolic process GO:1903362 44 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
regulation of nucleoside metabolic process GO:0009118 50 0.015
positive regulation of catabolic process GO:0009896 105 0.014
regulation of nuclear division GO:0051783 58 0.014
negative regulation of cell death GO:0060548 81 0.014
organelle fission GO:0048285 340 0.014
regulation of cytoplasmic transport GO:1903649 47 0.014
actin filament organization GO:0007015 126 0.014
cytokinesis GO:0000910 90 0.014
cellular homeostasis GO:0019725 80 0.014
regionalization GO:0003002 416 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
muscle organ development GO:0007517 127 0.014
g2 dna damage checkpoint GO:0031572 69 0.013
regulation of phosphorylation GO:0042325 147 0.013
molting cycle GO:0042303 56 0.013
regulation of anatomical structure size GO:0090066 163 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
receptor mediated endocytosis GO:0006898 21 0.013
regulation of protein stability GO:0031647 43 0.013
chromatin modification GO:0016568 147 0.013
mrna cis splicing via spliceosome GO:0045292 1 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
hemopoiesis GO:0030097 46 0.013
nitrogen compound transport GO:0071705 85 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
response to other organism GO:0051707 293 0.012
negative regulation of cellular catabolic process GO:0031330 34 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
protein import GO:0017038 55 0.012
response to starvation GO:0042594 97 0.012
maintenance of location GO:0051235 73 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
reproductive system development GO:0061458 74 0.012
regulation of molecular function GO:0065009 217 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
peripheral nervous system development GO:0007422 52 0.012
response to temperature stimulus GO:0009266 106 0.012
positive regulation of dna endoreduplication GO:0032877 4 0.012
positive regulation of signal transduction GO:0009967 223 0.012
development of primary sexual characteristics GO:0045137 50 0.012
rna localization GO:0006403 115 0.012
negative regulation of phosphatase activity GO:0010923 3 0.012
sister chromatid segregation GO:0000819 92 0.011
regulation of protein complex assembly GO:0043254 42 0.011
cell cycle checkpoint GO:0000075 95 0.011
protein ubiquitination GO:0016567 70 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
multi organism reproductive behavior GO:0044705 121 0.011
positive regulation of cell cycle GO:0045787 43 0.011
amine metabolic process GO:0009308 12 0.011
blood circulation GO:0008015 26 0.011
regulation of meiotic cell cycle GO:0051445 9 0.011
nitric oxide metabolic process GO:0046209 1 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
nuclear import GO:0051170 51 0.011
anterior posterior pattern specification GO:0009952 136 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
multi multicellular organism process GO:0044706 123 0.011
positive regulation of transport GO:0051050 92 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
positive regulation of developmental growth GO:0048639 62 0.010
regulation of mrna processing GO:0050684 71 0.010
regulation of intracellular protein transport GO:0033157 46 0.010
positive regulation of signaling GO:0023056 243 0.010
body morphogenesis GO:0010171 2 0.010
regulation of synaptic transmission GO:0050804 69 0.010
male gamete generation GO:0048232 201 0.010
positive regulation of cell cycle process GO:0090068 28 0.010
organic acid metabolic process GO:0006082 103 0.010
alternative mrna splicing via spliceosome GO:0000380 60 0.010

TfIIB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org