Drosophila melanogaster

13 known processes

Fib (Dmel_CG9888)

Fibrillarin

(Aliases: GCR6,GCR-6,pen59C5,Fibri,CG9888,Pen59C5,Dmel\CG9888)

Fib biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleoprotein complex biogenesis GO:0022613 31 0.720
Yeast
chromosome organization GO:0051276 360 0.426
Human Yeast
larval development GO:0002164 104 0.400
Worm
cell proliferation GO:0008283 299 0.357
embryo development ending in birth or egg hatching GO:0009792 152 0.267
Worm
negative regulation of cellular metabolic process GO:0031324 382 0.235
rrna processing GO:0006364 3 0.189
Yeast
ncrna metabolic process GO:0034660 43 0.182
Yeast
spindle organization GO:0007051 253 0.180
cell motility GO:0048870 251 0.167
Worm
regulation of cell cycle GO:0051726 291 0.164
organelle assembly GO:0070925 198 0.155
spindle assembly GO:0051225 80 0.150
cellular macromolecular complex assembly GO:0034622 153 0.137
death GO:0016265 284 0.135
rna processing GO:0006396 147 0.132
Yeast
endocytosis GO:0006897 310 0.129
spindle assembly involved in mitosis GO:0090307 50 0.127
nuclear division GO:0000280 332 0.107
development of primary sexual characteristics GO:0045137 50 0.106
Worm
ribosome biogenesis GO:0042254 8 0.104
Yeast
reproductive structure development GO:0048608 74 0.104
Worm
macromolecular complex assembly GO:0065003 256 0.095
sex differentiation GO:0007548 81 0.094
Worm
cell death GO:0008219 279 0.094
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.091
body morphogenesis GO:0010171 2 0.088
organelle fission GO:0048285 340 0.085
regulation of apoptotic process GO:0042981 130 0.085
mitotic spindle elongation GO:0000022 81 0.079
reproductive system development GO:0061458 74 0.076
Worm
protein complex biogenesis GO:0070271 201 0.073
determination of adult lifespan GO:0008340 137 0.072
mitotic spindle organization GO:0007052 220 0.072
rna splicing via transesterification reactions GO:0000375 73 0.071
regulation of cell cycle process GO:0010564 181 0.069
immune system process GO:0002376 347 0.068
growth GO:0040007 359 0.068
vesicle mediated transport GO:0016192 381 0.063
apoptotic process GO:0006915 159 0.063
ribosomal large subunit biogenesis GO:0042273 1 0.063
programmed cell death GO:0012501 257 0.062
positive regulation of biosynthetic process GO:0009891 316 0.060
Worm
catabolic process GO:0009056 409 0.057
cell growth GO:0016049 108 0.056
cellular catabolic process GO:0044248 372 0.055
regulation of programmed cell death GO:0043067 152 0.054
homeostatic process GO:0042592 199 0.053
nucleobase containing compound catabolic process GO:0034655 165 0.053
regulation of cell death GO:0010941 173 0.052
gland development GO:0048732 191 0.050
protein complex assembly GO:0006461 200 0.049
regulation of response to stress GO:0080134 200 0.049
localization of cell GO:0051674 257 0.048
Worm
chromatin organization GO:0006325 207 0.048
Human Yeast
aging GO:0007568 143 0.046
mrna metabolic process GO:0016071 124 0.046
dna metabolic process GO:0006259 227 0.046
macromolecule catabolic process GO:0009057 161 0.045
cellular macromolecule catabolic process GO:0044265 136 0.045
positive regulation of cellular biosynthetic process GO:0031328 316 0.044
Worm
ribonucleoprotein complex subunit organization GO:0071826 28 0.042
rna splicing GO:0008380 83 0.041
rna catabolic process GO:0006401 37 0.041
aromatic compound catabolic process GO:0019439 166 0.040
gonad development GO:0008406 50 0.039
Worm
negative regulation of rna metabolic process GO:0051253 251 0.039
regulation of growth GO:0040008 233 0.039
heterocycle catabolic process GO:0046700 166 0.038
ribonucleoprotein complex assembly GO:0022618 23 0.037
negative regulation of cell death GO:0060548 81 0.037
negative regulation of response to stimulus GO:0048585 258 0.037
phagocytosis GO:0006909 215 0.037
posttranscriptional regulation of gene expression GO:0010608 145 0.036
Worm
multicellular organismal aging GO:0010259 140 0.036
organic substance catabolic process GO:1901575 308 0.036
immune effector process GO:0002252 98 0.036
spindle elongation GO:0051231 83 0.035
cell migration GO:0016477 238 0.035
Worm
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
Worm
negative regulation of programmed cell death GO:0043069 72 0.034
phosphorylation GO:0016310 294 0.034
regulation of cell growth GO:0001558 43 0.032
regulation of multicellular organismal development GO:2000026 414 0.032
regulation of anatomical structure morphogenesis GO:0022603 242 0.032
negative regulation of apoptotic process GO:0043066 63 0.031
camera type eye development GO:0043010 4 0.031
appendage morphogenesis GO:0035107 397 0.029
dna damage checkpoint GO:0000077 78 0.029
regulation of immune response GO:0050776 118 0.029
organic cyclic compound catabolic process GO:1901361 168 0.029
tissue morphogenesis GO:0048729 297 0.028
mitotic nuclear division GO:0007067 213 0.026
regulation of cell proliferation GO:0042127 163 0.026
morphogenesis of an epithelium GO:0002009 276 0.026
regulation of mitotic cell cycle GO:0007346 190 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.025
regulation of developmental growth GO:0048638 174 0.025
mrna processing GO:0006397 104 0.025
protein destabilization GO:0031648 2 0.025
histone modification GO:0016570 106 0.024
Human Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.023
regulation of meiosis GO:0040020 3 0.023
innate immune response GO:0045087 144 0.022
mitotic dna integrity checkpoint GO:0044774 75 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.021
alpha amino acid metabolic process GO:1901605 20 0.021
mrna catabolic process GO:0006402 33 0.021
negative regulation of cell communication GO:0010648 223 0.021
regulation of cell development GO:0060284 215 0.021
chromatin modification GO:0016568 147 0.021
Human Yeast
developmental growth GO:0048589 280 0.020
mitotic cell cycle phase transition GO:0044772 138 0.020
nuclear rna surveillance GO:0071027 3 0.020
immune response activating signal transduction GO:0002757 2 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
mrna splicing via spliceosome GO:0000398 73 0.019
ncrna processing GO:0034470 30 0.019
Yeast
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
negative regulation of cell cycle GO:0045786 116 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
regulation of innate immune response GO:0045088 71 0.017
response to abiotic stimulus GO:0009628 341 0.016
protein phosphorylation GO:0006468 169 0.016
base excision repair GO:0006284 2 0.016
cell cycle phase transition GO:0044770 140 0.016
immune system development GO:0002520 57 0.016
glutamine metabolic process GO:0006541 4 0.016
imaginal disc derived appendage development GO:0048737 399 0.015
positive regulation of gene expression GO:0010628 290 0.015
Worm
receptor mediated endocytosis GO:0006898 21 0.015
negative regulation of signal transduction GO:0009968 206 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
regulation of defense response GO:0031347 102 0.015
regulation of cellular response to stress GO:0080135 89 0.015
cellular protein modification process GO:0006464 438 0.015
Human Yeast
muscle tissue morphogenesis GO:0060415 2 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
regulation of molecular function GO:0065009 217 0.014
cell recognition GO:0008037 102 0.014
production of molecular mediator of immune response GO:0002440 46 0.014
establishment of chromosome localization GO:0051303 20 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
regulation of dna metabolic process GO:0051052 34 0.014
regulation of immune system process GO:0002682 176 0.013
regulation of protein metabolic process GO:0051246 256 0.013
Worm
muscle structure development GO:0061061 224 0.013
small molecule metabolic process GO:0044281 305 0.013
response to external biotic stimulus GO:0043207 293 0.013
regulation of response to biotic stimulus GO:0002831 63 0.013
ras protein signal transduction GO:0007265 88 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
immune response GO:0006955 246 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
Worm
negative regulation of biosynthetic process GO:0009890 277 0.013
hemopoiesis GO:0030097 46 0.013
negative regulation of signaling GO:0023057 219 0.012
regulation of phosphorylation GO:0042325 147 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
nucleosome organization GO:0034728 59 0.012
organonitrogen compound metabolic process GO:1901564 318 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
regulation of hydrolase activity GO:0051336 97 0.011
spliceosomal snrnp assembly GO:0000387 2 0.011
mitotic g2 dna damage checkpoint GO:0007095 69 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
Worm
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
positive regulation of binding GO:0051099 4 0.011
nucleobase containing compound transport GO:0015931 56 0.011
wing disc morphogenesis GO:0007472 344 0.011
regulation of neurogenesis GO:0050767 158 0.011
anatomical structure homeostasis GO:0060249 97 0.011
kidney development GO:0001822 3 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 0 0.010
regulation of mrna metabolic process GO:1903311 72 0.010
centrosome duplication GO:0051298 121 0.010
nuclear transport GO:0051169 72 0.010
meiotic cell cycle GO:0051321 171 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010

Fib disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.012