Drosophila melanogaster

134 known processes

Dcp-1 (Dmel_CG5370)

Death caspase-1

(Aliases: CG5370,Dcp1,DCP1,dcp1,l(2)02132,Dmel\CG5370,DCP-1,l(2)01862,dcp-1,ccp1)

Dcp-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
developmental programmed cell death GO:0010623 138 0.980
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.978
Fly
apoptotic signaling pathway GO:0097190 27 0.948
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.944
Fly
regulation of cysteine type endopeptidase activity GO:2000116 27 0.929
Fly
regulation of cell differentiation GO:0045595 302 0.926
Fly
cell death GO:0008219 279 0.892
positive regulation of endopeptidase activity GO:0010950 26 0.884
Fly
programmed cell death GO:0012501 257 0.821
nurse cell apoptotic process GO:0045476 17 0.807
positive regulation of biosynthetic process GO:0009891 316 0.791
Fly
dendrite development GO:0016358 204 0.783
Fly
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.768
Fly
positive regulation of autophagy GO:0010508 21 0.765
chorion containing eggshell formation GO:0007304 105 0.751
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.747
Fly
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.740
regulation of cell death GO:0010941 173 0.727
Fly
ectopic germ cell programmed cell death GO:0035234 8 0.720
Fly
negative regulation of programmed cell death GO:0043069 72 0.716
Fly
regulation of multicellular organismal development GO:2000026 414 0.702
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.695
positive regulation of cell death GO:0010942 69 0.678
Fly
positive regulation of programmed cell death GO:0043068 62 0.673
Fly
eggshell chorion assembly GO:0007306 66 0.670
regulation of response to stress GO:0080134 200 0.629
regulation of programmed cell death GO:0043067 152 0.611
Fly
posttranscriptional gene silencing by rna GO:0035194 45 0.605
intrinsic apoptotic signaling pathway GO:0097193 16 0.603
cellular protein modification process GO:0006464 438 0.601
positive regulation of peptidase activity GO:0010952 29 0.564
Fly
regulation of apoptotic process GO:0042981 130 0.540
Fly
dorsal appendage formation GO:0046843 47 0.537
eggshell formation GO:0030703 105 0.535
regulation of autophagy GO:0010506 62 0.509
ovarian follicle cell development GO:0030707 248 0.477
regulation of cell development GO:0060284 215 0.475
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.471
Fly
immune system process GO:0002376 347 0.470
Fly
regulation of endopeptidase activity GO:0052548 36 0.468
Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.462
Fly
cellular response to extracellular stimulus GO:0031668 64 0.445
positive regulation of macroautophagy GO:0016239 8 0.438
apoptotic process GO:0006915 159 0.432
regionalization GO:0003002 416 0.428
proteolysis GO:0006508 192 0.426
autophagy GO:0006914 108 0.424
response to external biotic stimulus GO:0043207 293 0.376
Fly
positive regulation of cell communication GO:0010647 250 0.373
organic acid metabolic process GO:0006082 103 0.364
negative regulation of cellular metabolic process GO:0031324 382 0.362
protein modification process GO:0036211 438 0.357
gland morphogenesis GO:0022612 145 0.352
positive regulation of macromolecule metabolic process GO:0010604 405 0.350
Fly
positive regulation of cellular protein metabolic process GO:0032270 118 0.344
Fly
negative regulation of cell differentiation GO:0045596 143 0.340
compound eye retinal cell programmed cell death GO:0046667 23 0.339
Fly
regulation of molecular function GO:0065009 217 0.329
Fly
appendage morphogenesis GO:0035107 397 0.324
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.322
epithelial cell differentiation GO:0030855 322 0.315
protein modification by small protein conjugation or removal GO:0070647 106 0.311
positive regulation of protein metabolic process GO:0051247 128 0.306
Fly
posttranscriptional gene silencing GO:0016441 46 0.302
imaginal disc derived appendage development GO:0048737 399 0.296
imaginal disc derived wing morphogenesis GO:0007476 337 0.286
cellular component assembly involved in morphogenesis GO:0010927 151 0.284
cellular response to external stimulus GO:0071496 66 0.282
positive regulation of molecular function GO:0044093 136 0.282
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.278
Fly
protein phosphorylation GO:0006468 169 0.276
regulation of immune system process GO:0002682 176 0.276
Fly
death GO:0016265 284 0.272
regulation of peptidase activity GO:0052547 39 0.259
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.257
cellular catabolic process GO:0044248 372 0.257
oxoacid metabolic process GO:0043436 103 0.253
organonitrogen compound metabolic process GO:1901564 318 0.249
Fly
appendage development GO:0048736 401 0.246
sensory organ morphogenesis GO:0090596 260 0.242
Fly
regulation of phosphorylation GO:0042325 147 0.240
apoptotic process involved in development GO:1902742 20 0.237
carboxylic acid metabolic process GO:0019752 92 0.235
tissue morphogenesis GO:0048729 297 0.233
epithelial cell development GO:0002064 274 0.225
regulation of protein metabolic process GO:0051246 256 0.224
Fly
regulation of gene expression epigenetic GO:0040029 128 0.219
cellular ketone metabolic process GO:0042180 24 0.217
morphogenesis of an epithelium GO:0002009 276 0.217
intracellular signal transduction GO:0035556 300 0.213
positive regulation of response to extracellular stimulus GO:0032106 8 0.206
catabolic process GO:0009056 409 0.204
negative regulation of gene expression GO:0010629 387 0.201
cellular response to dna damage stimulus GO:0006974 223 0.201
regulation of cellular amine metabolic process GO:0033238 3 0.196
response to biotic stimulus GO:0009607 294 0.189
Fly
cellular response to chemical stimulus GO:0070887 199 0.183
regulation of neuron differentiation GO:0045664 103 0.180
positive regulation of signaling GO:0023056 243 0.179
Fly
compound eye morphogenesis GO:0001745 249 0.179
Fly
positive regulation of signal transduction GO:0009967 223 0.176
Fly
tube morphogenesis GO:0035239 191 0.173
protein modification by small protein conjugation GO:0032446 79 0.172
dna metabolic process GO:0006259 227 0.171
regulation of nervous system development GO:0051960 248 0.169
regulation of immune response GO:0050776 118 0.167
Fly
morphogenesis of a polarized epithelium GO:0001738 93 0.165
tissue death GO:0016271 102 0.164
response to other organism GO:0051707 293 0.160
Fly
single organism cell adhesion GO:0098602 47 0.159
positive regulation of apoptotic signaling pathway GO:2001235 4 0.157
Fly
cell type specific apoptotic process GO:0097285 38 0.156
larval development GO:0002164 104 0.155
regulation of neurogenesis GO:0050767 158 0.154
wnt signaling pathway GO:0016055 98 0.153
positive regulation of response to stimulus GO:0048584 323 0.150
execution phase of apoptosis GO:0097194 7 0.149
response to abiotic stimulus GO:0009628 341 0.149
Fly
digestive system development GO:0055123 149 0.147
wing disc morphogenesis GO:0007472 344 0.145
digestive tract morphogenesis GO:0048546 127 0.144
regulation of cellular ketone metabolic process GO:0010565 3 0.141
regulation of cell cycle process GO:0010564 181 0.139
cellular response to starvation GO:0009267 61 0.139
cellular amino acid metabolic process GO:0006520 61 0.134
regulation of apoptotic signaling pathway GO:2001233 10 0.133
Fly
regulation of cellular response to stress GO:0080135 89 0.131
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.129
photoreceptor cell differentiation GO:0046530 170 0.128
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.127
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.127
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.126
regulation of execution phase of apoptosis GO:1900117 5 0.125
regulation of catalytic activity GO:0050790 185 0.122
Fly
hemopoiesis GO:0030097 46 0.119
phosphorylation GO:0016310 294 0.119
aromatic compound catabolic process GO:0019439 166 0.116
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.116
positive regulation of proteolysis GO:0045862 52 0.113
Fly
axon development GO:0061564 297 0.110
single organism cellular localization GO:1902580 180 0.108
peptidyl amino acid modification GO:0018193 105 0.107
cellular macromolecule catabolic process GO:0044265 136 0.105
chemotaxis GO:0006935 249 0.105
positive regulation of phosphorylation GO:0042327 87 0.103
r3 r4 cell differentiation GO:0048056 12 0.102
zymogen activation GO:0031638 20 0.102
Fly
dendrite morphogenesis GO:0048813 199 0.101
Fly
positive regulation of cell development GO:0010720 61 0.100
Fly
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.100
Fly
salivary gland cell autophagic cell death GO:0035071 83 0.098
developmental maturation GO:0021700 172 0.096
amine metabolic process GO:0009308 12 0.096
cellular amine metabolic process GO:0044106 12 0.096
retina development in camera type eye GO:0060041 4 0.095
positive regulation of transcription dna templated GO:0045893 266 0.095
Fly
embryonic morphogenesis GO:0048598 206 0.093
Fly
cell cycle arrest GO:0007050 4 0.093
embryo development ending in birth or egg hatching GO:0009792 152 0.093
Fly
negative regulation of cell cycle GO:0045786 116 0.093
defense response to other organism GO:0098542 225 0.092
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.091
protein localization GO:0008104 284 0.090
negative regulation of apoptotic process GO:0043066 63 0.090
single organism catabolic process GO:0044712 228 0.090
establishment of planar polarity GO:0001736 87 0.090
positive regulation of nucleic acid templated transcription GO:1903508 266 0.089
Fly
cellular response to nutrient levels GO:0031669 62 0.089
organic substance catabolic process GO:1901575 308 0.089
peptidyl lysine acetylation GO:0018394 39 0.088
protein ubiquitination GO:0016567 70 0.088
activation of cysteine type endopeptidase activity GO:0097202 17 0.088
Fly
cellular nitrogen compound catabolic process GO:0044270 165 0.088
positive regulation of catalytic activity GO:0043085 118 0.087
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.086
organic cyclic compound catabolic process GO:1901361 168 0.085
asymmetric cell division GO:0008356 37 0.084
eye morphogenesis GO:0048592 260 0.084
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.083
positive regulation of cellular biosynthetic process GO:0031328 316 0.083
Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.081
Fly
macroautophagy GO:0016236 42 0.081
regulation of defense response GO:0031347 102 0.081
Fly
cardiovascular system development GO:0072358 82 0.079
pigment metabolic process GO:0042440 84 0.078
Fly
positive regulation of immune response GO:0050778 63 0.078
Fly
positive regulation of cell differentiation GO:0045597 64 0.077
Fly
establishment of tissue polarity GO:0007164 87 0.077
immune response GO:0006955 246 0.077
Fly
exocrine system development GO:0035272 162 0.077
sex differentiation GO:0007548 81 0.076
columnar cuboidal epithelial cell development GO:0002066 249 0.075
renal system development GO:0072001 72 0.075
single organism behavior GO:0044708 391 0.074
eye photoreceptor cell fate commitment GO:0042706 37 0.074
positive regulation of apoptotic process GO:0043065 47 0.073
Fly
rna interference GO:0016246 27 0.073
anatomical structure homeostasis GO:0060249 97 0.072
mitotic cell cycle phase transition GO:0044772 138 0.072
positive regulation of immune system process GO:0002684 68 0.071
Fly
mapk cascade GO:0000165 107 0.071
photoreceptor cell development GO:0042461 96 0.070
salivary gland morphogenesis GO:0007435 145 0.070
cellular response to heat GO:0034605 24 0.069
positive regulation of intracellular signal transduction GO:1902533 116 0.069
mitochondrion organization GO:0007005 65 0.069
regulation of wnt signaling pathway GO:0030111 68 0.069
regulation of cell projection organization GO:0031344 92 0.067
negative regulation of cell death GO:0060548 81 0.067
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.067
endocytosis GO:0006897 310 0.067
chromatin modification GO:0016568 147 0.066
epithelial tube morphogenesis GO:0060562 88 0.066
histolysis GO:0007559 102 0.066
lateral inhibition GO:0046331 206 0.066
regulation of actin filament based process GO:0032970 42 0.066
cellular response to sterol depletion GO:0071501 3 0.065
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.065
defense response to bacterium GO:0042742 178 0.064
Fly
mitotic dna integrity checkpoint GO:0044774 75 0.064
extrinsic apoptotic signaling pathway GO:0097191 1 0.064
regulation of mapk cascade GO:0043408 92 0.063
gliogenesis GO:0042063 80 0.062
positive regulation of hydrolase activity GO:0051345 78 0.062
Fly
negative regulation of cell communication GO:0010648 223 0.062
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.061
imaginal disc pattern formation GO:0007447 91 0.061
mitotic dna damage checkpoint GO:0044773 74 0.061
phagocytosis GO:0006909 215 0.060
segmentation GO:0035282 207 0.060
compound eye photoreceptor cell differentiation GO:0001751 140 0.060
regulation of phosphate metabolic process GO:0019220 210 0.060
locomotory behavior GO:0007626 176 0.060
protein processing GO:0016485 68 0.059
Fly
compound eye development GO:0048749 307 0.058
Fly
dna alkylation GO:0006305 4 0.057
growth GO:0040007 359 0.057
negative regulation of developmental process GO:0051093 201 0.056
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.055
positive regulation of retinal cell programmed cell death GO:0046670 9 0.055
Fly
regulation of response to nutrient levels GO:0032107 18 0.055
regulation of localization GO:0032879 275 0.055
adult behavior GO:0030534 137 0.055
regulation of canonical wnt signaling pathway GO:0060828 15 0.054
gland development GO:0048732 191 0.053
reproductive system development GO:0061458 74 0.053
establishment of localization in cell GO:0051649 402 0.052
regulation of cell cycle GO:0051726 291 0.051
regulation of response to external stimulus GO:0032101 115 0.051
regulation of anatomical structure size GO:0090066 163 0.051
stem cell maintenance GO:0019827 67 0.051
homeostatic process GO:0042592 199 0.051
eye photoreceptor cell differentiation GO:0001754 145 0.050
vesicle mediated transport GO:0016192 381 0.050
single organismal cell cell adhesion GO:0016337 45 0.050
negative regulation of cell cycle process GO:0010948 109 0.050
camera type eye morphogenesis GO:0048593 2 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.049
Fly
gene silencing by rna GO:0031047 57 0.049
signal transduction by p53 class mediator GO:0072331 6 0.049
taxis GO:0042330 304 0.048
negative regulation of rna biosynthetic process GO:1902679 240 0.048
regulation of innate immune response GO:0045088 71 0.047
Fly
signal transduction in response to dna damage GO:0042770 3 0.046
histone modification GO:0016570 106 0.046
regulation of proteolysis GO:0030162 87 0.046
Fly
regulation of neuron death GO:1901214 26 0.045
regulation of cellular component biogenesis GO:0044087 201 0.045
negative regulation of transcription dna templated GO:0045892 237 0.045
regulation of protein secretion GO:0050708 13 0.045
eye development GO:0001654 323 0.044
Fly
regulation of retinal cell programmed cell death GO:0046668 18 0.044
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.044
cell maturation GO:0048469 144 0.044
cell division GO:0051301 248 0.044
regulation of multi organism process GO:0043900 131 0.043
Fly
negative regulation of cell proliferation GO:0008285 69 0.043
Fly
blastoderm segmentation GO:0007350 159 0.043
regulation of embryonic development GO:0045995 68 0.043
enzyme linked receptor protein signaling pathway GO:0007167 179 0.043
negative regulation of signaling GO:0023057 219 0.042
axonogenesis GO:0007409 290 0.042
cell cell signaling involved in cell fate commitment GO:0045168 210 0.041
regulation of catabolic process GO:0009894 170 0.041
dna damage checkpoint GO:0000077 78 0.041
protein acetylation GO:0006473 39 0.041
protein transport GO:0015031 155 0.041
mitotic cell cycle embryonic GO:0045448 38 0.040
camera type eye development GO:0043010 4 0.040
neuron projection guidance GO:0097485 241 0.040
hindgut development GO:0061525 58 0.040
negative regulation of signal transduction GO:0009968 206 0.040
ncrna 3 end processing GO:0043628 17 0.040
cytoplasmic transport GO:0016482 130 0.039
small molecule metabolic process GO:0044281 305 0.039
regulation of stem cell proliferation GO:0072091 40 0.038
histone acetylation GO:0016573 38 0.038
positive regulation of rna metabolic process GO:0051254 271 0.037
Fly
gonad development GO:0008406 50 0.037
negative regulation of neurogenesis GO:0050768 53 0.037
regulation of macroautophagy GO:0016241 15 0.036
humoral immune response GO:0006959 117 0.036
Fly
positive regulation of protein modification process GO:0031401 58 0.035
positive regulation of phosphorus metabolic process GO:0010562 139 0.035
response to growth factor GO:0070848 31 0.035
regulation of cellular catabolic process GO:0031329 157 0.035
negative regulation of cellular biosynthetic process GO:0031327 277 0.034
compound eye photoreceptor development GO:0042051 78 0.034
regulation of cell morphogenesis GO:0022604 163 0.034
stem cell differentiation GO:0048863 117 0.033
regulation of cell proliferation GO:0042127 163 0.033
Fly
regulation of response to biotic stimulus GO:0002831 63 0.033
Fly
negative regulation of cell cycle phase transition GO:1901988 103 0.033
regulation of cellular localization GO:0060341 136 0.032
posttranscriptional regulation of gene expression GO:0010608 145 0.032
membrane organization GO:0061024 112 0.032
response to bacterium GO:0009617 198 0.032
Fly
regulation of hydrolase activity GO:0051336 97 0.031
Fly
response to ionizing radiation GO:0010212 32 0.031
Fly
macromolecule catabolic process GO:0009057 161 0.031
positive regulation of phosphate metabolic process GO:0045937 139 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.031
regulation of embryonic cell shape GO:0016476 30 0.031
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.030
biological adhesion GO:0022610 138 0.030
negative regulation of biosynthetic process GO:0009890 277 0.030
gene silencing GO:0016458 138 0.030
regulation of intracellular transport GO:0032386 64 0.030
cell migration GO:0016477 238 0.030
respiratory system development GO:0060541 213 0.030
hemocyte differentiation GO:0042386 38 0.029
Fly
protein maturation GO:0051604 71 0.029
Fly
mitotic spindle organization GO:0007052 220 0.029
kidney development GO:0001822 3 0.029
establishment of protein localization GO:0045184 163 0.029
cell adhesion GO:0007155 136 0.029
multicellular organismal aging GO:0010259 140 0.029
Fly
cellular amide metabolic process GO:0043603 80 0.029
Fly
nucleus organization GO:0006997 45 0.029
forebrain development GO:0030900 2 0.028
eye photoreceptor cell development GO:0042462 81 0.028
open tracheal system development GO:0007424 204 0.028
chromosome organization GO:0051276 360 0.028
dna integrity checkpoint GO:0031570 81 0.028
germ line stem cell maintenance GO:0030718 50 0.027
glial cell differentiation GO:0010001 35 0.027
negative regulation of cellular component organization GO:0051129 108 0.027
regulation of response to extracellular stimulus GO:0032104 18 0.027
neurological system process GO:0050877 358 0.027
positive regulation of stem cell proliferation GO:2000648 8 0.026
neuron death GO:0070997 27 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
dna replication initiation GO:0006270 6 0.026
positive regulation of developmental process GO:0051094 143 0.025
Fly
negative regulation of rna metabolic process GO:0051253 251 0.025
body morphogenesis GO:0010171 2 0.025
ocellus pigment metabolic process GO:0046158 19 0.025
central nervous system development GO:0007417 201 0.025
Fly
hematopoietic or lymphoid organ development GO:0048534 57 0.024
nuclear dna replication GO:0033260 1 0.024
regulation of protein ubiquitination GO:0031396 22 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
neuroblast proliferation GO:0007405 74 0.023
signal transduction by phosphorylation GO:0023014 107 0.023
cellular component disassembly GO:0022411 46 0.023
regulation of cell division GO:0051302 72 0.023
brain development GO:0007420 120 0.022
defense response GO:0006952 300 0.022
Fly
regulation of mitotic cell cycle phase transition GO:1901990 130 0.022
spermatogenesis GO:0007283 200 0.022
Fly
regulation of meiosis GO:0040020 3 0.022
salivary gland histolysis GO:0035070 88 0.022
cellular homeostasis GO:0019725 80 0.022
protein heterooligomerization GO:0051291 4 0.021
Fly
establishment of protein localization to organelle GO:0072594 62 0.021
negative regulation of protein modification process GO:0031400 29 0.021
negative regulation of chromosome segregation GO:0051985 14 0.021
tissue homeostasis GO:0001894 36 0.021
positive regulation of protein phosphorylation GO:0001934 34 0.020
embryonic organ development GO:0048568 50 0.020
neuron fate commitment GO:0048663 50 0.020
positive regulation of mapk cascade GO:0043410 63 0.020
single organism intracellular transport GO:1902582 207 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
Fly
nucleocytoplasmic transport GO:0006913 72 0.019
heterocycle catabolic process GO:0046700 166 0.019
nuclear transport GO:0051169 72 0.019
salivary gland development GO:0007431 162 0.019
regulation of protein modification process GO:0031399 112 0.019
protein localization to organelle GO:0033365 82 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.018
Fly
cell growth GO:0016049 108 0.018
covalent chromatin modification GO:0016569 106 0.018
apoptotic cell clearance GO:0043277 14 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
cellular response to growth factor stimulus GO:0071363 30 0.018
regulation of chromosome segregation GO:0051983 32 0.018
protein localization to nucleus GO:0034504 55 0.018
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.018
dna catabolic process GO:0006308 16 0.018
response to organic cyclic compound GO:0014070 89 0.018
digestive tract development GO:0048565 149 0.018
germarium derived egg chamber formation GO:0007293 101 0.018
mesenchymal cell development GO:0014031 1 0.018
mrna splicing via spliceosome GO:0000398 73 0.018
cell motility GO:0048870 251 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
localization of cell GO:0051674 257 0.017
negative regulation of organelle organization GO:0010639 56 0.017
photoreceptor cell fate commitment GO:0046552 41 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
organic substance transport GO:0071702 257 0.017
response to starvation GO:0042594 97 0.017
canonical wnt signaling pathway GO:0060070 21 0.017
neuron apoptotic process GO:0051402 17 0.017
nuclear import GO:0051170 51 0.017
regulation of transport GO:0051049 181 0.017
anterior posterior pattern specification GO:0009952 136 0.017
intracellular transport GO:0046907 228 0.017
stem cell proliferation GO:0072089 88 0.017
negative regulation of nervous system development GO:0051961 92 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
protein complex assembly GO:0006461 200 0.016
Fly
reproductive structure development GO:0048608 74 0.016
positive regulation of gene expression GO:0010628 290 0.016
Fly
establishment of ommatidial planar polarity GO:0042067 49 0.016
hindbrain development GO:0030902 2 0.016
negative regulation of response to stimulus GO:0048585 258 0.015
regulation of neuron projection development GO:0010975 69 0.015
kidney morphogenesis GO:0060993 3 0.015
positive regulation of nervous system development GO:0051962 69 0.015
organelle fission GO:0048285 340 0.015
neural precursor cell proliferation GO:0061351 75 0.015
regulation of neuron apoptotic process GO:0043523 16 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
regulation of protein localization GO:0032880 76 0.015
gastrulation GO:0007369 70 0.015
notch signaling pathway GO:0007219 120 0.015
fertilization GO:0009566 26 0.014
regulation of humoral immune response GO:0002920 51 0.014
Fly
protein polyubiquitination GO:0000209 11 0.014
innate immune response GO:0045087 144 0.014
Fly
development of primary sexual characteristics GO:0045137 50 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.014
telencephalon development GO:0021537 2 0.014
cell cycle dna replication GO:0044786 23 0.014
renal tubule development GO:0061326 64 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
secondary metabolic process GO:0019748 75 0.014
Fly
stem cell development GO:0048864 79 0.014
regulation of protein complex assembly GO:0043254 42 0.014
protein targeting to nucleus GO:0044744 51 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.014
cell proliferation GO:0008283 299 0.014
Fly
regulation of erk1 and erk2 cascade GO:0070372 39 0.014
multicellular organismal homeostasis GO:0048871 41 0.014
positive regulation of stress fiber assembly GO:0051496 3 0.013
regulation of protein kinase activity GO:0045859 51 0.013
immune effector process GO:0002252 98 0.013
Fly
peptidyl tyrosine modification GO:0018212 24 0.013
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.013
Fly
gene silencing by mirna GO:0035195 22 0.013
cell cycle checkpoint GO:0000075 95 0.013
protein targeting GO:0006605 64 0.013
aging GO:0007568 143 0.013
Fly
regulation of protein phosphorylation GO:0001932 64 0.013
renal tubule morphogenesis GO:0061333 44 0.012
response to alcohol GO:0097305 95 0.012
organ growth GO:0035265 56 0.012
response to organophosphorus GO:0046683 2 0.012
protein complex disassembly GO:0043241 36 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of protein transport GO:0051223 57 0.012
regulation of phosphatase activity GO:0010921 3 0.012
macromolecular complex assembly GO:0065003 256 0.012
Fly
regulation of notch signaling pathway GO:0008593 100 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
regulation of immune effector process GO:0002697 52 0.012
Fly
r3 r4 cell fate commitment GO:0007464 10 0.012
compound eye photoreceptor fate commitment GO:0001752 36 0.012
response to nutrient levels GO:0031667 114 0.011
positive regulation of defense response GO:0031349 59 0.011
Fly
chemical homeostasis GO:0048878 92 0.011
response to transforming growth factor beta GO:0071559 18 0.011
cell fate determination GO:0001709 91 0.011
meiotic nuclear division GO:0007126 151 0.011
autophagic cell death GO:0048102 83 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
Fly

Dcp-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.028
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
musculoskeletal system cancer DOID:0060100 0 0.014
connective tissue cancer DOID:201 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012