Drosophila melanogaster

38 known processes

inx7 (Dmel_CG2977)

innexin 7

(Aliases: CG32731,D-inx-7,prp7,Dmel\CG2977,Dm-inx7,inx-7,CG2977)

inx7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic morphogenesis GO:0048598 206 0.410
Fly
learning or memory GO:0007611 141 0.349
response to abiotic stimulus GO:0009628 341 0.265
neurological system process GO:0050877 358 0.218
tissue morphogenesis GO:0048729 297 0.207
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.196
memory GO:0007613 94 0.195
appendage development GO:0048736 401 0.187
response to oxygen containing compound GO:1901700 200 0.182
long term memory GO:0007616 62 0.178
response to light stimulus GO:0009416 124 0.173
central nervous system development GO:0007417 201 0.162
appendage morphogenesis GO:0035107 397 0.157
cognition GO:0050890 141 0.154
positive regulation of rna biosynthetic process GO:1902680 266 0.147
imaginal disc derived appendage morphogenesis GO:0035114 395 0.142
response to organic substance GO:0010033 284 0.118
learning GO:0007612 75 0.114
behavioral response to ethanol GO:0048149 49 0.113
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.110
endocytosis GO:0006897 310 0.108
vesicle mediated transport GO:0016192 381 0.105
immune system process GO:0002376 347 0.103
sensory organ morphogenesis GO:0090596 260 0.101
wing disc morphogenesis GO:0007472 344 0.098
response to radiation GO:0009314 155 0.096
eye development GO:0001654 323 0.090
morphogenesis of an epithelium GO:0002009 276 0.090
Fly
eye morphogenesis GO:0048592 260 0.088
taxis GO:0042330 304 0.087
positive regulation of macromolecule metabolic process GO:0010604 405 0.084
determination of adult lifespan GO:0008340 137 0.081
multicellular organismal aging GO:0010259 140 0.081
positive regulation of biosynthetic process GO:0009891 316 0.078
axon development GO:0061564 297 0.075
neuron projection guidance GO:0097485 241 0.074
regulation of multicellular organismal development GO:2000026 414 0.069
aging GO:0007568 143 0.069
positive regulation of nucleic acid templated transcription GO:1903508 266 0.069
morphogenesis of embryonic epithelium GO:0016331 94 0.069
Fly
compound eye morphogenesis GO:0001745 249 0.069
imaginal disc derived appendage development GO:0048737 399 0.068
response to alcohol GO:0097305 95 0.068
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.067
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.066
organelle fission GO:0048285 340 0.065
gliogenesis GO:0042063 80 0.062
respiratory system development GO:0060541 213 0.062
positive regulation of transcription dna templated GO:0045893 266 0.061
positive regulation of cellular biosynthetic process GO:0031328 316 0.061
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.060
positive regulation of gene expression GO:0010628 290 0.059
eye photoreceptor cell differentiation GO:0001754 145 0.059
positive regulation of response to stimulus GO:0048584 323 0.057
transcription from rna polymerase ii promoter GO:0006366 368 0.057
epithelial cell differentiation GO:0030855 322 0.056
melanin metabolic process GO:0006582 47 0.054
muscle structure development GO:0061061 224 0.054
immune response regulating signaling pathway GO:0002764 2 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.051
post embryonic appendage morphogenesis GO:0035120 385 0.049
compound eye development GO:0048749 307 0.047
organonitrogen compound metabolic process GO:1901564 318 0.046
nuclear division GO:0000280 332 0.045
embryonic development via the syncytial blastoderm GO:0001700 148 0.045
Fly
dorsal closure GO:0007391 79 0.044
Fly
positive regulation of cell communication GO:0010647 250 0.044
positive regulation of rna metabolic process GO:0051254 271 0.043
response to organonitrogen compound GO:0010243 75 0.043
skeletal muscle organ development GO:0060538 48 0.042
negative regulation of rna biosynthetic process GO:1902679 240 0.042
negative regulation of signaling GO:0023057 219 0.042
cell migration GO:0016477 238 0.041
cellular response to abiotic stimulus GO:0071214 58 0.041
protein complex biogenesis GO:0070271 201 0.040
protein complex assembly GO:0006461 200 0.040
response to high light intensity GO:0009644 1 0.039
cell proliferation GO:0008283 299 0.039
transmembrane transport GO:0055085 139 0.039
Fly
compound eye photoreceptor fate commitment GO:0001752 36 0.038
cellular response to radiation GO:0071478 52 0.038
axon guidance GO:0007411 233 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.037
photoreceptor cell fate commitment GO:0046552 41 0.037
negative regulation of gene expression GO:0010629 387 0.037
olfactory behavior GO:0042048 97 0.036
forebrain development GO:0030900 2 0.036
single organism behavior GO:0044708 391 0.036
peripheral nervous system development GO:0007422 52 0.035
regulation of response to stress GO:0080134 200 0.035
associative learning GO:0008306 65 0.035
kidney development GO:0001822 3 0.034
positive regulation of signaling GO:0023056 243 0.033
macromolecular complex assembly GO:0065003 256 0.033
negative regulation of cell communication GO:0010648 223 0.033
head development GO:0060322 135 0.033
developmental programmed cell death GO:0010623 138 0.032
cell cell junction assembly GO:0007043 38 0.032
photoreceptor cell differentiation GO:0046530 170 0.031
response to nitrogen compound GO:1901698 90 0.031
negative regulation of rna metabolic process GO:0051253 251 0.031
response to endogenous stimulus GO:0009719 119 0.030
digestive tract development GO:0048565 149 0.030
cellular response to light stimulus GO:0071482 37 0.030
limb morphogenesis GO:0035108 1 0.030
gland morphogenesis GO:0022612 145 0.030
tube development GO:0035295 244 0.030
adult behavior GO:0030534 137 0.030
cellular response to dna damage stimulus GO:0006974 223 0.029
intracellular receptor signaling pathway GO:0030522 19 0.029
muscle organ development GO:0007517 127 0.028
phagocytosis GO:0006909 215 0.028
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.028
intracellular signal transduction GO:0035556 300 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
embryo development ending in birth or egg hatching GO:0009792 152 0.028
Fly
chemical homeostasis GO:0048878 92 0.028
phosphorylation GO:0016310 294 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
negative regulation of biosynthetic process GO:0009890 277 0.027
regulation of cellular catabolic process GO:0031329 157 0.027
gland development GO:0048732 191 0.027
regionalization GO:0003002 416 0.027
immune response GO:0006955 246 0.026
dendrite morphogenesis GO:0048813 199 0.026
small molecule metabolic process GO:0044281 305 0.026
positive regulation of signal transduction GO:0009967 223 0.026
regulation of molecular function GO:0065009 217 0.026
secondary metabolic process GO:0019748 75 0.025
salivary gland histolysis GO:0035070 88 0.025
regulation of response to external stimulus GO:0032101 115 0.025
immune response activating signal transduction GO:0002757 2 0.025
catabolic process GO:0009056 409 0.025
cell fate specification GO:0001708 71 0.024
organophosphate metabolic process GO:0019637 195 0.024
histolysis GO:0007559 102 0.024
response to organic cyclic compound GO:0014070 89 0.023
protein modification process GO:0036211 438 0.023
localization of cell GO:0051674 257 0.023
regulation of organ morphogenesis GO:2000027 78 0.023
camera type eye development GO:0043010 4 0.023
cell motility GO:0048870 251 0.023
cell junction organization GO:0034330 57 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
protein heterooligomerization GO:0051291 4 0.023
carboxylic acid metabolic process GO:0019752 92 0.022
positive regulation of molecular function GO:0044093 136 0.022
cellular response to light intensity GO:0071484 1 0.022
purine containing compound metabolic process GO:0072521 155 0.022
regulation of immune response GO:0050776 118 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
protein localization GO:0008104 284 0.022
l amino acid import GO:0043092 2 0.022
locomotory behavior GO:0007626 176 0.021
striated muscle cell differentiation GO:0051146 90 0.021
nephron development GO:0072006 3 0.021
muscle cell differentiation GO:0042692 103 0.021
regulation of localization GO:0032879 275 0.021
exocrine system development GO:0035272 162 0.020
columnar cuboidal epithelial cell development GO:0002066 249 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
phototaxis GO:0042331 21 0.020
proteolysis GO:0006508 192 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
pigmentation GO:0043473 75 0.020
dephosphorylation GO:0016311 51 0.020
body morphogenesis GO:0010171 2 0.020
ion transmembrane transport GO:0034220 122 0.020
axonogenesis GO:0007409 290 0.020
brain development GO:0007420 120 0.020
anatomical structure homeostasis GO:0060249 97 0.020
ion transport GO:0006811 145 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.020
cellular amino acid metabolic process GO:0006520 61 0.019
melanization defense response GO:0035006 45 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
positive regulation of transport GO:0051050 92 0.019
response to external biotic stimulus GO:0043207 293 0.019
intracellular transport GO:0046907 228 0.019
immune effector process GO:0002252 98 0.019
pigment metabolic process GO:0042440 84 0.019
limb development GO:0060173 1 0.019
cholesterol homeostasis GO:0042632 3 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
organic substance catabolic process GO:1901575 308 0.019
death GO:0016265 284 0.019
amine metabolic process GO:0009308 12 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
response to glucose GO:0009749 2 0.018
tube morphogenesis GO:0035239 191 0.018
centrosome duplication GO:0051298 121 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
salivary gland development GO:0007431 162 0.018
cell death GO:0008219 279 0.018
establishment of protein localization GO:0045184 163 0.018
regulation of cell proliferation GO:0042127 163 0.018
mesenchymal cell differentiation GO:0048762 1 0.018
positive regulation of programmed cell death GO:0043068 62 0.018
activation of innate immune response GO:0002218 4 0.018
dna metabolic process GO:0006259 227 0.018
innate immune response GO:0045087 144 0.018
connective tissue development GO:0061448 3 0.017
regulation of catalytic activity GO:0050790 185 0.017
epithelial tube morphogenesis GO:0060562 88 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
autophagic cell death GO:0048102 83 0.017
cellular response to high light intensity GO:0071486 1 0.017
actin filament based process GO:0030029 220 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
inorganic ion transmembrane transport GO:0098660 73 0.017
photoreceptor cell axon guidance GO:0072499 23 0.017
neuron fate commitment GO:0048663 50 0.017
urogenital system development GO:0001655 72 0.017
myotube differentiation GO:0014902 46 0.017
developmental maturation GO:0021700 172 0.017
tissue death GO:0016271 102 0.016
salivary gland cell autophagic cell death GO:0035071 83 0.016
eye photoreceptor cell fate commitment GO:0042706 37 0.016
chemosensory behavior GO:0007635 106 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
positive regulation of immune response GO:0050778 63 0.016
regulation of immune system process GO:0002682 176 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
cation transmembrane transport GO:0098655 88 0.016
embryonic organ development GO:0048568 50 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
mitotic nuclear division GO:0007067 213 0.016
multi multicellular organism process GO:0044706 123 0.016
positive regulation of immune system process GO:0002684 68 0.016
nurse cell apoptotic process GO:0045476 17 0.016
organelle assembly GO:0070925 198 0.016
regulation of proteolysis GO:0030162 87 0.016
cellular protein modification process GO:0006464 438 0.015
ethanolamine containing compound metabolic process GO:0042439 4 0.015
eye pigment metabolic process GO:0042441 33 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
response to oxidative stress GO:0006979 86 0.015
telencephalon development GO:0021537 2 0.015
olfactory learning GO:0008355 56 0.015
response to ethanol GO:0045471 59 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
membrane organization GO:0061024 112 0.015
cellular catabolic process GO:0044248 372 0.015
digestive system development GO:0055123 149 0.015
photoreceptor cell development GO:0042461 96 0.015
spermatogenesis GO:0007283 200 0.014
cellular amine metabolic process GO:0044106 12 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
neuromuscular junction development GO:0007528 149 0.014
salivary gland morphogenesis GO:0007435 145 0.014
endomembrane system organization GO:0010256 119 0.014
cation homeostasis GO:0055080 51 0.014
protein transport GO:0015031 155 0.014
positive regulation of developmental process GO:0051094 143 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
defense response GO:0006952 300 0.014
response to other organism GO:0051707 293 0.014
antimicrobial humoral response GO:0019730 99 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
neuron recognition GO:0008038 101 0.013
response to biotic stimulus GO:0009607 294 0.013
reactive oxygen species metabolic process GO:0072593 22 0.013
regulation of catabolic process GO:0009894 170 0.013
single organism intracellular transport GO:1902582 207 0.013
cell projection assembly GO:0030031 94 0.013
regulation of cell division GO:0051302 72 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
regulation of neurogenesis GO:0050767 158 0.013
metal ion transport GO:0030001 74 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
response to lipid GO:0033993 38 0.013
male gamete generation GO:0048232 201 0.013
cellular homeostasis GO:0019725 80 0.013
response to temperature stimulus GO:0009266 106 0.013
immune system development GO:0002520 57 0.013
organophosphate catabolic process GO:0046434 112 0.013
endodermal cell differentiation GO:0035987 3 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
homeostatic process GO:0042592 199 0.012
multi organism behavior GO:0051705 175 0.012
cell cell junction organization GO:0045216 55 0.012
social behavior GO:0035176 4 0.012
negative regulation of synapse assembly GO:0051964 39 0.012
mesenchymal cell development GO:0014031 1 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
response to lipopolysaccharide GO:0032496 4 0.012
multi organism reproductive behavior GO:0044705 121 0.012
cell adhesion GO:0007155 136 0.012
regulation of cellular response to stress GO:0080135 89 0.012
regulation of protein metabolic process GO:0051246 256 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
regulation of transferase activity GO:0051338 58 0.012
positive regulation of cell motility GO:2000147 3 0.012
negative regulation of signal transduction GO:0009968 206 0.012
apoptotic process GO:0006915 159 0.012
glial cell development GO:0021782 27 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
organic substance transport GO:0071702 257 0.012
signal transduction in response to dna damage GO:0042770 3 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
gtp metabolic process GO:0046039 72 0.012
wnt signaling pathway GO:0016055 98 0.012
nuclear transport GO:0051169 72 0.012
monocarboxylic acid transport GO:0015718 3 0.012
sulfur compound metabolic process GO:0006790 59 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
embryonic pattern specification GO:0009880 174 0.011
synaptic transmission GO:0007268 288 0.011
meiotic cell cycle GO:0051321 171 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
camera type eye morphogenesis GO:0048593 2 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
lateral inhibition GO:0046331 206 0.011
triglyceride biosynthetic process GO:0019432 2 0.011
nucleotide metabolic process GO:0009117 161 0.011
cellular macromolecule localization GO:0070727 220 0.011
positive regulation of calcium ion transport GO:0051928 4 0.011
cellular response to organic substance GO:0071310 132 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
negative regulation of growth GO:0045926 84 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
epidermis development GO:0008544 65 0.011
gravitaxis GO:0042332 26 0.011
organic acid metabolic process GO:0006082 103 0.011
chemotaxis GO:0006935 249 0.011
regulation of cell differentiation GO:0045595 302 0.011
chromosome organization GO:0051276 360 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
chromosome segregation GO:0007059 157 0.011
male mating behavior GO:0060179 70 0.011
formation of organ boundary GO:0010160 30 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
female meiotic division GO:0007143 70 0.011
cellularization GO:0007349 90 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
glandular epithelial cell differentiation GO:0002067 1 0.011
regulation of transport GO:0051049 181 0.011
choline catabolic process GO:0042426 1 0.010
ras protein signal transduction GO:0007265 88 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
purine containing compound catabolic process GO:0072523 112 0.010
energy taxis GO:0009453 21 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
developmental pigmentation GO:0048066 68 0.010
protein processing GO:0016485 68 0.010
meiotic cell cycle process GO:1903046 132 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
protein targeting to nucleus GO:0044744 51 0.010
establishment of localization in cell GO:0051649 402 0.010
detection of stimulus GO:0051606 156 0.010
muscle cell development GO:0055001 50 0.010
hemocyte migration GO:0035099 19 0.010
regulation of protein modification process GO:0031399 112 0.010
spermatid differentiation GO:0048515 114 0.010
ventral cord development GO:0007419 16 0.010

inx7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
musculoskeletal system disease DOID:17 0 0.039
connective tissue disease DOID:65 0 0.039
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.019
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
bone disease DOID:0080001 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
acquired metabolic disease DOID:0060158 0 0.012