Drosophila melanogaster

111 known processes

lid (Dmel_CG9088)

little imaginal discs

(Aliases: Lid,dJARID1,l(2)10424,KDM5,CG9088,Dmel\CG9088)

lid biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription dna templated GO:0045892 237 0.964
Human Mouse
gene silencing GO:0016458 138 0.949
negative regulation of cellular biosynthetic process GO:0031327 277 0.939
Human Mouse
regulation of gene expression epigenetic GO:0040029 128 0.898
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.879
Human Mouse
negative regulation of gene expression GO:0010629 387 0.803
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.732
Human Mouse
regulation of gene silencing GO:0060968 63 0.700
negative regulation of biosynthetic process GO:0009890 277 0.691
Human Mouse
chromosome organization GO:0051276 360 0.676
chromatin silencing GO:0006342 76 0.670
circadian rhythm GO:0007623 105 0.665
circadian behavior GO:0048512 76 0.634
regulation of chromatin silencing GO:0031935 36 0.603
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.587
Human Mouse
negative regulation of rna metabolic process GO:0051253 251 0.584
Human Mouse
gene silencing by mirna GO:0035195 22 0.575
negative regulation of signal transduction GO:0009968 206 0.560
negative regulation of signaling GO:0023057 219 0.533
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.515
Human Mouse
locomotor rhythm GO:0045475 56 0.504
negative regulation of cellular metabolic process GO:0031324 382 0.492
Human Mouse
dna metabolic process GO:0006259 227 0.486
rhythmic behavior GO:0007622 76 0.485
negative regulation of rna biosynthetic process GO:1902679 240 0.483
Human Mouse
rhythmic process GO:0048511 106 0.467
regulation of intracellular signal transduction GO:1902531 236 0.453
neurological system process GO:0050877 358 0.447
negative regulation of gene expression epigenetic GO:0045814 77 0.446
peptidyl lysine modification GO:0018205 57 0.442
negative regulation of nucleic acid templated transcription GO:1903507 240 0.397
Human Mouse
aggressive behavior GO:0002118 63 0.380
gravitaxis GO:0042332 26 0.373
central nervous system development GO:0007417 201 0.372
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.360
inter male aggressive behavior GO:0002121 60 0.342
histone deubiquitination GO:0016578 8 0.335
negative regulation of cell communication GO:0010648 223 0.333
positive regulation of biosynthetic process GO:0009891 316 0.326
mitotic cell cycle embryonic GO:0045448 38 0.319
positive regulation of cellular biosynthetic process GO:0031328 316 0.295
regulation of cellular catabolic process GO:0031329 157 0.289
positive regulation of transcription dna templated GO:0045893 266 0.279
cellular catabolic process GO:0044248 372 0.276
immune system process GO:0002376 347 0.265
cellular macromolecular complex assembly GO:0034622 153 0.253
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.248
dendrite morphogenesis GO:0048813 199 0.243
histone h4 acetylation GO:0043967 13 0.240
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.234
multi organism behavior GO:0051705 175 0.234
single organism behavior GO:0044708 391 0.224
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.222
response to abiotic stimulus GO:0009628 341 0.215
macromolecular complex assembly GO:0065003 256 0.215
chromatin organization GO:0006325 207 0.214
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.214
hindbrain development GO:0030902 2 0.210
ribonucleoprotein complex assembly GO:0022618 23 0.206
positive regulation of nucleic acid templated transcription GO:1903508 266 0.203
chromatin modification GO:0016568 147 0.202
autophagy GO:0006914 108 0.191
intracellular protein transport GO:0006886 104 0.178
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.177
response to gravity GO:0009629 26 0.172
positive regulation of rna biosynthetic process GO:1902680 266 0.169
locomotory behavior GO:0007626 176 0.167
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.166
covalent chromatin modification GO:0016569 106 0.164
protein alkylation GO:0008213 43 0.152
body morphogenesis GO:0010171 2 0.135
multicellular organismal aging GO:0010259 140 0.131
Worm
catabolic process GO:0009056 409 0.130
protein modification by small protein conjugation or removal GO:0070647 106 0.130
ribonucleoprotein complex subunit organization GO:0071826 28 0.126
negative regulation of response to stimulus GO:0048585 258 0.123
death GO:0016265 284 0.121
Zebrafish
negative regulation of chromatin silencing GO:0031936 9 0.116
regulation of compound eye cone cell fate specification GO:0042682 4 0.114
positive regulation of gene expression GO:0010628 290 0.111
positive regulation of gene expression epigenetic GO:0045815 16 0.108
positive regulation of rna metabolic process GO:0051254 271 0.106
heterocycle catabolic process GO:0046700 166 0.105
chromatin remodeling GO:0006338 72 0.104
protein modification by small protein conjugation GO:0032446 79 0.104
regulation of circadian rhythm GO:0042752 49 0.099
transcription from rna polymerase ii promoter GO:0006366 368 0.098
cellular protein catabolic process GO:0044257 83 0.098
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.095
macromolecule catabolic process GO:0009057 161 0.092
mitotic spindle organization GO:0007052 220 0.092
negative regulation of notch signaling pathway GO:0045746 41 0.092
gene silencing by rna GO:0031047 57 0.091
regulation of molecular function GO:0065009 217 0.090
Mouse
dendrite development GO:0016358 204 0.087
histone modification GO:0016570 106 0.087
regulation of stem cell proliferation GO:0072091 40 0.085
negative regulation of stem cell proliferation GO:2000647 30 0.083
response to radiation GO:0009314 155 0.082
organic substance catabolic process GO:1901575 308 0.081
protein ubiquitination GO:0016567 70 0.077
cellular macromolecule catabolic process GO:0044265 136 0.077
response to alcohol GO:0097305 95 0.077
methylation GO:0032259 47 0.073
immune system development GO:0002520 57 0.068
mitotic cell cycle phase transition GO:0044772 138 0.068
negative regulation of neuroblast proliferation GO:0007406 27 0.065
dna methylation GO:0006306 4 0.063
internal protein amino acid acetylation GO:0006475 38 0.063
nuclear division GO:0000280 332 0.062
dorsal ventral pattern formation GO:0009953 133 0.059
single organism catabolic process GO:0044712 228 0.059
dosage compensation GO:0007549 16 0.059
mrna metabolic process GO:0016071 124 0.057
dna methylation or demethylation GO:0044728 4 0.057
regulation of protein ubiquitination GO:0031396 22 0.057
rna catabolic process GO:0006401 37 0.057
aging GO:0007568 143 0.057
Worm
chromatin mediated maintenance of transcription GO:0048096 7 0.055
jak stat cascade GO:0007259 49 0.054
posttranscriptional gene silencing by rna GO:0035194 45 0.054
cellular response to dna damage stimulus GO:0006974 223 0.053
negative regulation of apoptotic process GO:0043066 63 0.051
Zebrafish
regulation of mitotic cell cycle GO:0007346 190 0.051
cellular response to organic cyclic compound GO:0071407 32 0.050
regulation of neuroblast proliferation GO:1902692 34 0.049
protein targeting to nucleus GO:0044744 51 0.049
startle response GO:0001964 16 0.047
positive regulation of cell death GO:0010942 69 0.047
dna damage checkpoint GO:0000077 78 0.047
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.046
telomere maintenance GO:0000723 21 0.046
purine ribonucleotide metabolic process GO:0009150 145 0.045
r7 cell differentiation GO:0045466 43 0.045
chromosome condensation GO:0030261 41 0.044
anatomical structure homeostasis GO:0060249 97 0.043
cell death GO:0008219 279 0.043
Zebrafish
regulation of cell cycle phase transition GO:1901987 130 0.043
head development GO:0060322 135 0.043
phagocytosis GO:0006909 215 0.043
dna alkylation GO:0006305 4 0.040
eye photoreceptor cell fate commitment GO:0042706 37 0.040
meiotic chromosome segregation GO:0045132 59 0.039
regionalization GO:0003002 416 0.039
cellular response to light stimulus GO:0071482 37 0.038
aromatic compound catabolic process GO:0019439 166 0.038
protein complex assembly GO:0006461 200 0.038
organic substance transport GO:0071702 257 0.038
regulation of erbb signaling pathway GO:1901184 42 0.038
regulation of nucleocytoplasmic transport GO:0046822 35 0.038
translation GO:0006412 69 0.038
negative regulation of cell cycle phase transition GO:1901988 103 0.037
taxis GO:0042330 304 0.037
mrna catabolic process GO:0006402 33 0.037
small gtpase mediated signal transduction GO:0007264 88 0.037
stem cell proliferation GO:0072089 88 0.037
compound eye photoreceptor fate commitment GO:0001752 36 0.036
histone acetylation GO:0016573 38 0.036
regulation of protein metabolic process GO:0051246 256 0.036
Mouse
nuclear envelope organization GO:0006998 7 0.036
mitotic nuclear division GO:0007067 213 0.035
signal transduction in response to dna damage GO:0042770 3 0.035
positive regulation of chromatin silencing GO:0031937 16 0.034
establishment of localization in cell GO:0051649 402 0.034
regulation of cell differentiation GO:0045595 302 0.034
rna processing GO:0006396 147 0.034
enzyme linked receptor protein signaling pathway GO:0007167 179 0.034
programmed cell death GO:0012501 257 0.033
Zebrafish
regulation of hydrolase activity GO:0051336 97 0.033
Mouse
posttranscriptional gene silencing GO:0016441 46 0.033
negative regulation of chromosome segregation GO:0051985 14 0.033
protein acylation GO:0043543 42 0.033
cellular response to external stimulus GO:0071496 66 0.032
localization of cell GO:0051674 257 0.032
negative regulation of cellular protein metabolic process GO:0032269 85 0.032
Mouse
neuromuscular process GO:0050905 21 0.032
positive regulation of cellular catabolic process GO:0031331 95 0.032
regulation of cell proliferation GO:0042127 163 0.032
r1 r6 cell differentiation GO:0048052 4 0.031
long term memory GO:0007616 62 0.031
regulation of chromosome organization GO:0033044 64 0.031
Mouse
cell aging GO:0007569 2 0.031
compound eye cone cell fate commitment GO:0042676 5 0.031
cellular protein complex assembly GO:0043623 71 0.031
cellular response to organic substance GO:0071310 132 0.030
ribonucleoprotein complex biogenesis GO:0022613 31 0.030
positive regulation of macromolecule metabolic process GO:0010604 405 0.030
larval development GO:0002164 104 0.030
Worm
neuron fate commitment GO:0048663 50 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
cell proliferation GO:0008283 299 0.027
chemosensory behavior GO:0007635 106 0.027
endocytosis GO:0006897 310 0.027
male courtship behavior veined wing generated song production GO:0045433 20 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.027
apoptotic process GO:0006915 159 0.027
Zebrafish
small molecule metabolic process GO:0044281 305 0.027
exocrine system development GO:0035272 162 0.026
regulation of proteolysis GO:0030162 87 0.026
female meiotic division GO:0007143 70 0.025
posttranscriptional regulation of gene expression GO:0010608 145 0.024
nuclear pore organization GO:0006999 1 0.024
photoreceptor cell fate commitment GO:0046552 41 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
neuroblast proliferation GO:0007405 74 0.024
compound eye development GO:0048749 307 0.023
humoral immune response GO:0006959 117 0.023
cell cycle checkpoint GO:0000075 95 0.023
negative regulation of intracellular signal transduction GO:1902532 57 0.023
response to sterol GO:0036314 34 0.022
dna integrity checkpoint GO:0031570 81 0.022
protein modification process GO:0036211 438 0.022
brain development GO:0007420 120 0.021
nucleocytoplasmic transport GO:0006913 72 0.021
negative regulation of catabolic process GO:0009895 36 0.021
cellular response to abiotic stimulus GO:0071214 58 0.021
regulation of mrna processing GO:0050684 71 0.021
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.021
ubiquitin dependent protein catabolic process GO:0006511 78 0.021
single organism biosynthetic process GO:0044711 206 0.021
ribose phosphate metabolic process GO:0019693 145 0.020
positive regulation of molecular function GO:0044093 136 0.020
response to extracellular stimulus GO:0009991 116 0.020
compound eye cone cell differentiation GO:0042675 13 0.020
signal transduction by p53 class mediator GO:0072331 6 0.020
negative regulation of cell death GO:0060548 81 0.020
Zebrafish
mitotic dna integrity checkpoint GO:0044774 75 0.020
macromolecule methylation GO:0043414 45 0.020
oviposition GO:0018991 19 0.020
response to starvation GO:0042594 97 0.019
regulation of cytoplasmic transport GO:1903649 47 0.019
appendage morphogenesis GO:0035107 397 0.019
regulation of cell development GO:0060284 215 0.019
regulation of catabolic process GO:0009894 170 0.019
nucleus organization GO:0006997 45 0.019
male courtship behavior veined wing vibration GO:0016545 21 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
positive regulation of cell cycle GO:0045787 43 0.018
telomere organization GO:0032200 21 0.018
mrna splicing via spliceosome GO:0000398 73 0.018
meiotic chromosome condensation GO:0010032 3 0.018
negative regulation of cell cycle process GO:0010948 109 0.017
regulation of cell fate commitment GO:0010453 29 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
organelle localization GO:0051640 148 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
Mouse
regulation of protein targeting GO:1903533 29 0.017
purine containing compound catabolic process GO:0072523 112 0.017
protein import GO:0017038 55 0.017
regulation of nucleobase containing compound transport GO:0032239 4 0.017
histone h3 acetylation GO:0043966 11 0.017
cellular response to oxidative stress GO:0034599 28 0.017
axon guidance GO:0007411 233 0.016
dna recombination GO:0006310 32 0.016
response to nitrogen compound GO:1901698 90 0.016
regulation of mrna metabolic process GO:1903311 72 0.016
negative regulation of translation GO:0017148 28 0.016
g2 m transition of mitotic cell cycle GO:0000086 19 0.016
growth GO:0040007 359 0.016
icosanoid biosynthetic process GO:0046456 1 0.015
mesenchymal cell development GO:0014031 1 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
determination of adult lifespan GO:0008340 137 0.015
Worm
positive regulation of protein deacetylation GO:0090312 2 0.015
ncrna metabolic process GO:0034660 43 0.015
regulation of translation GO:0006417 56 0.015
translesion synthesis GO:0019985 2 0.015
protein complex biogenesis GO:0070271 201 0.015
male courtship behavior veined wing extension GO:0048065 22 0.015
negative regulation of neural precursor cell proliferation GO:2000178 27 0.015
chromosome segregation GO:0007059 157 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
regulation of autophagy GO:0010506 62 0.014
response to organic substance GO:0010033 284 0.014
response to oxidative stress GO:0006979 86 0.014
regulation of chromatin modification GO:1903308 28 0.014
Mouse
cell motility GO:0048870 251 0.014
response to other organism GO:0051707 293 0.014
sex differentiation GO:0007548 81 0.014
regulation of organelle organization GO:0033043 196 0.014
Mouse
glycosyl compound metabolic process GO:1901657 127 0.014
mrna processing GO:0006397 104 0.014
positive regulation of apoptotic process GO:0043065 47 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
protein processing GO:0016485 68 0.014
regulation of chromosome segregation GO:0051983 32 0.014
eggshell chorion gene amplification GO:0007307 9 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
protein transport GO:0015031 155 0.014
organelle fission GO:0048285 340 0.013
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.013
protein acetylation GO:0006473 39 0.013
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.013
secretion GO:0046903 109 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
negative regulation of developmental process GO:0051093 201 0.013
regulation of glial cell differentiation GO:0045685 1 0.013
response to organic cyclic compound GO:0014070 89 0.013
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.013
regulation of localization GO:0032879 275 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.013
single organism cellular localization GO:1902580 180 0.012
regulation of protein complex assembly GO:0043254 42 0.012
wing disc pattern formation GO:0035222 66 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
protein import into nucleus GO:0006606 51 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
cellular response to ketone GO:1901655 17 0.012
positive regulation of catabolic process GO:0009896 105 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
filtration diaphragm assembly GO:0036058 4 0.012
pigment cell differentiation GO:0050931 3 0.012
hematopoietic or lymphoid organ development GO:0048534 57 0.012
sensory perception of mechanical stimulus GO:0050954 72 0.012
cell fate determination GO:0001709 91 0.012
cell cycle phase transition GO:0044770 140 0.012
wing disc morphogenesis GO:0007472 344 0.012
regulation of catalytic activity GO:0050790 185 0.012
Mouse
reproductive behavior GO:0019098 122 0.012
nucleoside metabolic process GO:0009116 127 0.012
protein methylation GO:0006479 43 0.012
response to nutrient levels GO:0031667 114 0.012
camera type eye development GO:0043010 4 0.012
antennal development GO:0007469 25 0.012
sensory organ precursor cell fate determination GO:0016360 19 0.012
histone h4 k16 acetylation GO:0043984 4 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
male meiosis chromosome segregation GO:0007060 10 0.011
proteolysis GO:0006508 192 0.011
response to ketone GO:1901654 34 0.011
response to decreased oxygen levels GO:0036293 58 0.011
ommochrome biosynthetic process GO:0006727 19 0.011
appendage development GO:0048736 401 0.011
regulation of programmed cell death GO:0043067 152 0.011
Zebrafish
mitotic cell cycle checkpoint GO:0007093 88 0.011
regulation of protein import into nucleus GO:0042306 28 0.011
dna templated transcription initiation GO:0006352 25 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
spliceosomal complex assembly GO:0000245 1 0.011
regulation of transport GO:0051049 181 0.011
muscle fiber development GO:0048747 12 0.011
multi organism reproductive behavior GO:0044705 121 0.011
regulation of nurse cell apoptotic process GO:0045477 9 0.011
cytoplasmic mrna processing body assembly GO:0033962 10 0.011
regulation of secretion GO:0051046 44 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
male meiosis i GO:0007141 9 0.010
nuclear transport GO:0051169 72 0.010
regulation of neurogenesis GO:0050767 158 0.010
protein dna complex subunit organization GO:0071824 86 0.010
cellular response to hydrogen peroxide GO:0070301 7 0.010
smad protein import into nucleus GO:0007184 11 0.010
immune response GO:0006955 246 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.010
positive regulation of peptidase activity GO:0010952 29 0.010

lid disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org