Drosophila melanogaster

15 known processes

Yp2 (Dmel_CG2979)

Yolk protein 2

(Aliases: YP2,yp2,VIT2Dm,YP[[2]],YPII,YP-2,fs(1)A59,CG2979,fs(1)m35,fs(1)M35,yp,Dmel\CG2979,YP,fs(1)K313,VG2)

Yp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
triglyceride catabolic process GO:0019433 3 0.982
Human
anion homeostasis GO:0055081 3 0.930
Human
acylglycerol catabolic process GO:0046464 3 0.887
Human
acylglycerol biosynthetic process GO:0046463 2 0.846
Rat
phospholipid homeostasis GO:0055091 1 0.791
Human
glycerolipid catabolic process GO:0046503 3 0.761
Human Rat
neutral lipid catabolic process GO:0046461 3 0.760
Human Rat
triglyceride biosynthetic process GO:0019432 2 0.744
Rat
neutral lipid biosynthetic process GO:0046460 2 0.730
Rat
cholesterol homeostasis GO:0042632 3 0.728
Human
cholesterol transport GO:0030301 2 0.596
Human
regulation of sterol transport GO:0032371 1 0.551
Human
lipid homeostasis GO:0055088 33 0.511
Human
triglyceride metabolic process GO:0006641 12 0.441
Human Rat
fatty acid metabolic process GO:0006631 20 0.384
Human Rat
response to cold GO:0009409 13 0.372
Rat
chorion containing eggshell formation GO:0007304 105 0.315
lipid catabolic process GO:0016042 21 0.301
Human Rat
imaginal disc derived appendage morphogenesis GO:0035114 395 0.294
Fly
imaginal disc derived appendage development GO:0048737 399 0.288
Fly
response to abiotic stimulus GO:0009628 341 0.286
Rat
eggshell formation GO:0030703 105 0.285
regulation of localization GO:0032879 275 0.283
Human
acylglycerol metabolic process GO:0006639 12 0.260
Human Rat
neutral lipid metabolic process GO:0006638 12 0.255
Human Rat
innate immune response GO:0045087 144 0.253
post embryonic appendage morphogenesis GO:0035120 385 0.246
Fly
appendage morphogenesis GO:0035107 397 0.239
Fly
lipid metabolic process GO:0006629 121 0.231
Human Rat
triglyceride homeostasis GO:0070328 18 0.227
Human
appendage development GO:0048736 401 0.220
Fly
endocytosis GO:0006897 310 0.212
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.203
Fly
ion homeostasis GO:0050801 55 0.195
Human
catabolic process GO:0009056 409 0.190
Human Rat
wing disc morphogenesis GO:0007472 344 0.190
Fly
regulation of lipid transport GO:0032368 3 0.189
Human
small molecule biosynthetic process GO:0044283 37 0.181
Human
chemical homeostasis GO:0048878 92 0.176
Human
cellular lipid metabolic process GO:0044255 83 0.174
Human Rat
vesicle mediated transport GO:0016192 381 0.166
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.163
Human
phagocytosis GO:0006909 215 0.161
Fly
immune system process GO:0002376 347 0.159
cellular catabolic process GO:0044248 372 0.157
Human Rat
single organism catabolic process GO:0044712 228 0.152
Human Rat
pigment metabolic process involved in pigmentation GO:0043474 33 0.149
lipid biosynthetic process GO:0008610 46 0.144
Human Rat
regulation of transport GO:0051049 181 0.141
Human
oxoacid metabolic process GO:0043436 103 0.137
Human Rat
monocarboxylic acid metabolic process GO:0032787 29 0.132
Human Rat
cellular lipid catabolic process GO:0044242 16 0.131
Human Rat
ovarian follicle cell development GO:0030707 248 0.129
organic acid metabolic process GO:0006082 103 0.128
Human Rat
single organism biosynthetic process GO:0044711 206 0.124
Human Rat
carboxylic acid metabolic process GO:0019752 92 0.107
Human Rat
small molecule metabolic process GO:0044281 305 0.103
Human Rat
positive regulation of transport GO:0051050 92 0.101
Human
egg activation GO:0007343 9 0.097
acetaldehyde metabolic process GO:0006117 5 0.093
lipid localization GO:0010876 54 0.090
Human
pigment metabolic process GO:0042440 84 0.086
acylglycerol homeostasis GO:0055090 19 0.085
Human
organic substance catabolic process GO:1901575 308 0.081
Human Rat
organic substance transport GO:0071702 257 0.075
Human
cellular component assembly involved in morphogenesis GO:0010927 151 0.073
response to external biotic stimulus GO:0043207 293 0.071
epithelial cell differentiation GO:0030855 322 0.067
carboxylic acid biosynthetic process GO:0046394 15 0.064
Human
sterol homeostasis GO:0055092 4 0.062
Human
epithelial cell development GO:0002064 274 0.060
organic acid biosynthetic process GO:0016053 15 0.055
Human
adult behavior GO:0030534 137 0.054
homeostatic process GO:0042592 199 0.054
Human
monocarboxylic acid biosynthetic process GO:0072330 7 0.053
Human
response to fungus GO:0009620 50 0.051
single fertilization GO:0007338 24 0.050
extracellular matrix assembly GO:0085029 13 0.049
response to drug GO:0042493 17 0.049
Rat
axon development GO:0061564 297 0.048
protein modification process GO:0036211 438 0.048
protein localization GO:0008104 284 0.048
secondary metabolic process GO:0019748 75 0.044
single organism behavior GO:0044708 391 0.042
vitelline membrane formation GO:0030704 11 0.042
positive regulation of response to stimulus GO:0048584 323 0.041
eggshell chorion assembly GO:0007306 66 0.039
response to temperature stimulus GO:0009266 106 0.037
Rat
egg coat formation GO:0035803 11 0.035
transmembrane transport GO:0055085 139 0.034
immune response GO:0006955 246 0.033
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.033
positive regulation of cell communication GO:0010647 250 0.031
mitotic g2 m transition checkpoint GO:0044818 70 0.031
regulation of neurogenesis GO:0050767 158 0.031
synaptic transmission GO:0007268 288 0.031
regulation of synapse structure and activity GO:0050803 128 0.031
cellular ketone metabolic process GO:0042180 24 0.030
neuron recognition GO:0008038 101 0.030
pigmentation GO:0043473 75 0.029
positive regulation of signal transduction GO:0009967 223 0.029
developmental pigmentation GO:0048066 68 0.028
cell projection assembly GO:0030031 94 0.028
cellular amino acid metabolic process GO:0006520 61 0.028
Rat
defense response GO:0006952 300 0.027
cognition GO:0050890 141 0.027
lateral inhibition GO:0046331 206 0.027
extracellular matrix organization GO:0030198 32 0.027
columnar cuboidal epithelial cell development GO:0002066 249 0.027
extracellular structure organization GO:0043062 46 0.027
benzene containing compound metabolic process GO:0042537 3 0.027
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.026
establishment of organelle localization GO:0051656 122 0.026
positive regulation of signaling GO:0023056 243 0.026
axonogenesis GO:0007409 290 0.026
vitelline membrane formation involved in chorion containing eggshell formation GO:0007305 11 0.026
cellular response to dna damage stimulus GO:0006974 223 0.026
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.025
regulation of membrane potential GO:0042391 35 0.025
dna metabolic process GO:0006259 227 0.025
establishment of localization in cell GO:0051649 402 0.024
gene silencing GO:0016458 138 0.024
response to organic substance GO:0010033 284 0.024
Rat
cell motility GO:0048870 251 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
Rat
secretion by cell GO:0032940 101 0.023
synapse assembly GO:0007416 143 0.023
defense response to other organism GO:0098542 225 0.023
carbohydrate metabolic process GO:0005975 82 0.023
response to hexose GO:0009746 3 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
gland development GO:0048732 191 0.022
Rat
regulation of cell cycle phase transition GO:1901987 130 0.022
developmental growth GO:0048589 280 0.022
Rat
regulation of secretion by cell GO:1903530 39 0.021
axon guidance GO:0007411 233 0.021
protein complex biogenesis GO:0070271 201 0.021
Rat
camera type eye development GO:0043010 4 0.021
melanotic encapsulation of foreign target GO:0035011 30 0.021
response to glucose GO:0009749 2 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
mating GO:0007618 120 0.021
regulation of cell cycle GO:0051726 291 0.021
protein heterooligomerization GO:0051291 4 0.021
negative regulation of cell cycle process GO:0010948 109 0.021
rna localization GO:0006403 115 0.020
eye pigmentation GO:0048069 43 0.020
gliogenesis GO:0042063 80 0.020
cell cycle checkpoint GO:0000075 95 0.020
intracellular signal transduction GO:0035556 300 0.020
dendrite development GO:0016358 204 0.020
proteolysis GO:0006508 192 0.020
regulation of cholesterol transport GO:0032374 1 0.020
Human
regulation of cellular amine metabolic process GO:0033238 3 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
learning or memory GO:0007611 141 0.020
g2 dna damage checkpoint GO:0031572 69 0.019
protein transmembrane transport GO:0071806 4 0.019
neurological system process GO:0050877 358 0.019
response to monosaccharide GO:0034284 4 0.019
death GO:0016265 284 0.019
macromolecular complex assembly GO:0065003 256 0.018
Rat
protein transport GO:0015031 155 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
neuromuscular synaptic transmission GO:0007274 67 0.018
cellular protein localization GO:0034613 160 0.018
locomotory behavior GO:0007626 176 0.018
cellular amine metabolic process GO:0044106 12 0.018
Rat
organelle localization GO:0051640 148 0.018
regionalization GO:0003002 416 0.018
humoral immune response GO:0006959 117 0.018
pheromone biosynthetic process GO:0042811 3 0.018
positive regulation of cell death GO:0010942 69 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.017
dorsal appendage formation GO:0046843 47 0.017
forebrain development GO:0030900 2 0.017
g protein coupled receptor signaling pathway GO:0007186 136 0.017
eye photoreceptor cell development GO:0042462 81 0.017
dna conformation change GO:0071103 105 0.017
regulation of neuron differentiation GO:0045664 103 0.017
regulation of cellular localization GO:0060341 136 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
fatty acid biosynthetic process GO:0006633 6 0.017
Human
mitotic dna damage checkpoint GO:0044773 74 0.017
regulation of neuron projection development GO:0010975 69 0.017
chromosome organization GO:0051276 360 0.017
positive regulation of neurogenesis GO:0050769 41 0.017
secondary metabolite biosynthetic process GO:0044550 24 0.017
response to endogenous stimulus GO:0009719 119 0.017
Rat
regulation of response to stress GO:0080134 200 0.017
maintenance of location GO:0051235 73 0.016
Human
regulation of sequestering of triglyceride GO:0010889 3 0.016
Human
nitrogen compound transport GO:0071705 85 0.016
cellular macromolecule localization GO:0070727 220 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
negative regulation of gene expression GO:0010629 387 0.016
gene silencing by rna GO:0031047 57 0.016
melanization defense response GO:0035006 45 0.016
organophosphate metabolic process GO:0019637 195 0.016
Rat
chemosensory behavior GO:0007635 106 0.016
courtship behavior GO:0007619 68 0.016
single organismal cell cell adhesion GO:0016337 45 0.016
single organism intracellular transport GO:1902582 207 0.016
defense response to bacterium GO:0042742 178 0.015
intracellular transport GO:0046907 228 0.015
organelle assembly GO:0070925 198 0.015
response to oxygen containing compound GO:1901700 200 0.015
Rat
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
sleep GO:0030431 49 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
exocrine system development GO:0035272 162 0.015
regulation of synapse organization GO:0050807 110 0.015
axis specification GO:0009798 167 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
membrane depolarization GO:0051899 4 0.015
tissue morphogenesis GO:0048729 297 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
glycerolipid metabolic process GO:0046486 34 0.015
Human Rat
negative regulation of response to stimulus GO:0048585 258 0.015
rrna processing GO:0006364 3 0.014
nucleus organization GO:0006997 45 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
neuromuscular junction development GO:0007528 149 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
photoreceptor cell development GO:0042461 96 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
single organism cellular localization GO:1902580 180 0.014
regulation of cellular response to stress GO:0080135 89 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
response to other organism GO:0051707 293 0.014
ras protein signal transduction GO:0007265 88 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
response to transforming growth factor beta GO:0071559 18 0.014
regulation of mapk cascade GO:0043408 92 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of phosphate metabolic process GO:0019220 210 0.013
cell cycle phase transition GO:0044770 140 0.013
telencephalon development GO:0021537 2 0.013
synaptic target recognition GO:0008039 45 0.013
taxis GO:0042330 304 0.013
wnt signaling pathway GO:0016055 98 0.013
phenol containing compound metabolic process GO:0018958 57 0.013
body morphogenesis GO:0010171 2 0.013
kidney development GO:0001822 3 0.013
secretion GO:0046903 109 0.013
wound healing GO:0042060 75 0.013
programmed cell death GO:0012501 257 0.013
ocellus pigment metabolic process GO:0046158 19 0.013
fat soluble vitamin metabolic process GO:0006775 1 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
long chain fatty acid metabolic process GO:0001676 3 0.013
positive regulation of gene expression GO:0010628 290 0.013
phosphorylation GO:0016310 294 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
antimicrobial humoral response GO:0019730 99 0.013
nephron epithelium development GO:0072009 3 0.013
cellular modified amino acid metabolic process GO:0006575 45 0.013
Rat
mesoderm development GO:0007498 78 0.012
ion transmembrane transport GO:0034220 122 0.012
establishment of protein localization GO:0045184 163 0.012
response to wounding GO:0009611 94 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
regulation of synaptic transmission GO:0050804 69 0.012
nephron tubule development GO:0072080 3 0.012
positive regulation of synaptic transmission GO:0050806 15 0.012
response to biotic stimulus GO:0009607 294 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
immune effector process GO:0002252 98 0.012
adult locomotory behavior GO:0008344 76 0.012
retina development in camera type eye GO:0060041 4 0.012
camera type eye morphogenesis GO:0048593 2 0.012
rhythmic synaptic transmission GO:0060024 2 0.012
localization of cell GO:0051674 257 0.012
regulation of cell development GO:0060284 215 0.012
single organism cell adhesion GO:0098602 47 0.012
positive regulation of exocytosis GO:0045921 4 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
single organism membrane organization GO:0044802 93 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
motor neuron axon guidance GO:0008045 58 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
regulation of apoptotic process GO:0042981 130 0.012
pigment biosynthetic process GO:0046148 36 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
dorsal ventral axis specification GO:0009950 66 0.012
exocytosis GO:0006887 28 0.012
cell proliferation GO:0008283 299 0.011
Rat
nephron development GO:0072006 3 0.011
protein processing GO:0016485 68 0.011
response to copper ion GO:0046688 4 0.011
Rat
kidney morphogenesis GO:0060993 3 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
imaginal disc derived wing hair organization GO:0035317 45 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
synapse organization GO:0050808 196 0.011
nucleobase containing compound transport GO:0015931 56 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
negative regulation of signal transduction GO:0009968 206 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
regulation of anatomical structure size GO:0090066 163 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
cellular protein modification process GO:0006464 438 0.011
mitotic nuclear division GO:0007067 213 0.011
organic hydroxy compound catabolic process GO:1901616 4 0.011
cellular response to organic substance GO:0071310 132 0.011
Rat
encapsulation of foreign target GO:0035010 38 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
Rat
positive regulation of cell migration GO:0030335 2 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
Rat
compound eye photoreceptor development GO:0042051 78 0.011
limb morphogenesis GO:0035108 1 0.011
intracellular protein transmembrane import GO:0044743 4 0.011
response to lipopolysaccharide GO:0032496 4 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
regulation of endocytosis GO:0030100 37 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
regulation of molecular function GO:0065009 217 0.011
developmental programmed cell death GO:0010623 138 0.011
growth GO:0040007 359 0.011
Rat
mapk cascade GO:0000165 107 0.011
negative regulation of cell communication GO:0010648 223 0.010
melanin metabolic process GO:0006582 47 0.010
kidney epithelium development GO:0072073 3 0.010
rna processing GO:0006396 147 0.010
salivary gland development GO:0007431 162 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
positive regulation of synaptic transmission glutamatergic GO:0051968 3 0.010
cilium assembly GO:0042384 38 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
response to organophosphorus GO:0046683 2 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
regulation of dendrite development GO:0050773 37 0.010
axon extension GO:0048675 32 0.010
compound eye development GO:0048749 307 0.010
negative regulation of signaling GO:0023057 219 0.010
regulation of programmed cell death GO:0043067 152 0.010
activation of innate immune response GO:0002218 4 0.010
regulation of cell cycle process GO:0010564 181 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
negative regulation of biosynthetic process GO:0009890 277 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010

Yp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hair disease DOID:421 0 1.000
Human
disease of anatomical entity DOID:7 0 1.000
Human
integumentary system disease DOID:16 0 1.000
Human
hypotrichosis DOID:4535 0 1.000
Human
disease of metabolism DOID:0014667 0 0.999
Human
familial hypertriglyceridemia DOID:0050527 0 0.999
Human
lipid metabolism disorder DOID:3146 0 0.999
Human
inherited metabolic disorder DOID:655 0 0.999
Human
diabetes mellitus DOID:9351 0 0.651
Human
carbohydrate metabolism disease DOID:0050013 0 0.651
Human
glucose metabolism disease DOID:4194 0 0.651
Human
acquired metabolic disease DOID:0060158 0 0.651
Human
type 2 diabetes mellitus DOID:9352 0 0.499
Human
nervous system disease DOID:863 0 0.017
cardiovascular system disease DOID:1287 0 0.014
sensory system disease DOID:0050155 0 0.014