Drosophila melanogaster

137 known processes

msn (Dmel_CG16973)

misshapen

(Aliases: NIK,JNKKKK,Dmel\CG16973,l(3)j1E2,Msn,6286,l(3)6286,CG16973,MSN,Nik,HGK,MESR5,msm,DMSN,l(3)06946,l(3)03349)

msn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axon development GO:0061564 297 0.999
morphogenesis of an epithelium GO:0002009 276 0.999
cell migration GO:0016477 238 0.998
Human Worm
imaginal disc derived wing hair organization GO:0035317 45 0.996
embryonic development via the syncytial blastoderm GO:0001700 148 0.995
tissue morphogenesis GO:0048729 297 0.995
morphogenesis of embryonic epithelium GO:0016331 94 0.995
dorsal closure GO:0007391 79 0.994
embryonic morphogenesis GO:0048598 206 0.992
tube morphogenesis GO:0035239 191 0.991
Zebrafish
axonogenesis GO:0007409 290 0.988
tube development GO:0035295 244 0.987
Zebrafish
regulation of cell development GO:0060284 215 0.983
Human
synapse organization GO:0050808 196 0.978
regulation of anatomical structure size GO:0090066 163 0.977
morphogenesis of a polarized epithelium GO:0001738 93 0.974
compound eye development GO:0048749 307 0.974
digestive tract morphogenesis GO:0048546 127 0.969
Zebrafish
cell motility GO:0048870 251 0.968
Human Worm
digestive system development GO:0055123 149 0.963
Zebrafish
establishment of planar polarity GO:0001736 87 0.963
actin cytoskeleton reorganization GO:0031532 22 0.960
Human
cell junction assembly GO:0034329 42 0.956
compound eye morphogenesis GO:0001745 249 0.953
wing disc morphogenesis GO:0007472 344 0.948
digestive tract development GO:0048565 149 0.946
Zebrafish
post embryonic appendage morphogenesis GO:0035120 385 0.917
compound eye photoreceptor development GO:0042051 78 0.915
regulation of protein metabolic process GO:0051246 256 0.909
Human Mouse
neuron projection guidance GO:0097485 241 0.894
establishment of tissue polarity GO:0007164 87 0.869
regulation of cellular component size GO:0032535 98 0.868
establishment or maintenance of cell polarity GO:0007163 167 0.867
retinal ganglion cell axon guidance GO:0031290 12 0.862
localization of cell GO:0051674 257 0.859
Human Worm
taxis GO:0042330 304 0.853
regulation of actin cytoskeleton organization GO:0032956 42 0.851
compound eye photoreceptor cell differentiation GO:0001751 140 0.843
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.834
regulation of cell size GO:0008361 63 0.830
epithelial cell differentiation GO:0030855 322 0.830
actin cytoskeleton organization GO:0030036 206 0.826
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.822
establishment of localization in cell GO:0051649 402 0.810
sensory organ morphogenesis GO:0090596 260 0.808
protein modification process GO:0036211 438 0.804
Human Mouse
hair cell differentiation GO:0035315 47 0.794
regulation of cell cycle GO:0051726 291 0.794
non sensory hair organization GO:0035316 47 0.788
cellular protein complex assembly GO:0043623 71 0.777
rho protein signal transduction GO:0007266 14 0.776
imaginal disc derived wing morphogenesis GO:0007476 337 0.767
eye development GO:0001654 323 0.765
oocyte development GO:0048599 124 0.753
imaginal disc derived appendage development GO:0048737 399 0.751
cell junction organization GO:0034330 57 0.750
intracellular transport GO:0046907 228 0.746
cell recognition GO:0008037 102 0.737
imaginal disc derived appendage morphogenesis GO:0035114 395 0.731
establishment of ommatidial planar polarity GO:0042067 49 0.727
gastrulation GO:0007369 70 0.727
Zebrafish
epithelial cell development GO:0002064 274 0.723
regulation of cytoskeleton organization GO:0051493 89 0.723
stress fiber assembly GO:0043149 6 0.720
regulation of actin filament based process GO:0032970 42 0.716
ommatidial rotation GO:0016318 20 0.712
axon guidance GO:0007411 233 0.709
biological adhesion GO:0022610 138 0.705
Human
eye morphogenesis GO:0048592 260 0.702
actin filament bundle organization GO:0061572 28 0.702
actin filament organization GO:0007015 126 0.688
oocyte axis specification GO:0007309 108 0.665
actomyosin structure organization GO:0031032 56 0.665
immune effector process GO:0002252 98 0.661
immune response GO:0006955 246 0.654
developmental growth involved in morphogenesis GO:0060560 65 0.649
Worm
regulation of axonogenesis GO:0050770 32 0.641
oocyte construction GO:0007308 112 0.636
programmed cell death GO:0012501 257 0.614
response to wounding GO:0009611 94 0.612
motor neuron axon guidance GO:0008045 58 0.611
immune system process GO:0002376 347 0.610
Mouse
positive regulation of cell development GO:0010720 61 0.605
germarium derived egg chamber formation GO:0007293 101 0.602
regulation of actin filament polymerization GO:0030833 25 0.587
skin development GO:0043588 65 0.586
epithelial tube morphogenesis GO:0060562 88 0.563
cell death GO:0008219 279 0.556
ras protein signal transduction GO:0007265 88 0.553
actin filament based process GO:0030029 220 0.547
Human
regulation of cell differentiation GO:0045595 302 0.537
Human
negative regulation of signal transduction GO:0009968 206 0.533
negative regulation of cell communication GO:0010648 223 0.531
regulation of intracellular signal transduction GO:1902531 236 0.528
respiratory system development GO:0060541 213 0.524
non canonical wnt signaling pathway GO:0035567 8 0.518
regulation of stress fiber assembly GO:0051492 6 0.516
neuromuscular junction development GO:0007528 149 0.502
appendage development GO:0048736 401 0.499
eye photoreceptor cell development GO:0042462 81 0.492
cell projection assembly GO:0030031 94 0.492
regulation of phosphorus metabolic process GO:0051174 210 0.486
Human Mouse
regulation of response to external stimulus GO:0032101 115 0.482
chemotaxis GO:0006935 249 0.481
eye photoreceptor cell differentiation GO:0001754 145 0.479
regulation of cell projection organization GO:0031344 92 0.478
Human
positive regulation of jun kinase activity GO:0043507 4 0.478
Human Mouse
stem cell maintenance GO:0019827 67 0.460
protein localization GO:0008104 284 0.460
regulation of catabolic process GO:0009894 170 0.456
cellular macromolecule localization GO:0070727 220 0.456
initiation of dorsal closure GO:0007392 12 0.454
nephrocyte filtration GO:0097206 7 0.453
response to nutrient levels GO:0031667 114 0.443
morphogenesis of a branching epithelium GO:0061138 45 0.442
cell cell junction organization GO:0045216 55 0.442
regulation of immune system process GO:0002682 176 0.440
defense response GO:0006952 300 0.435
response to other organism GO:0051707 293 0.435
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.431
morphogenesis of a branching structure GO:0001763 45 0.430
regulation of actin polymerization or depolymerization GO:0008064 27 0.429
regulation of small gtpase mediated signal transduction GO:0051056 93 0.424
regulation of cell death GO:0010941 173 0.424
regulation of neuron differentiation GO:0045664 103 0.421
Human
oocyte differentiation GO:0009994 145 0.418
actin filament bundle assembly GO:0051017 26 0.417
single organism cellular localization GO:1902580 180 0.415
defense response to other organism GO:0098542 225 0.415
regulation of localization GO:0032879 275 0.407
Human
gastrulation involving germ band extension GO:0010004 36 0.402
regulation of phosphate metabolic process GO:0019220 210 0.400
Human Mouse
photoreceptor cell differentiation GO:0046530 170 0.396
single organism catabolic process GO:0044712 228 0.389
neuron recognition GO:0008038 101 0.387
catabolic process GO:0009056 409 0.384
positive regulation of cellular component organization GO:0051130 156 0.365
synapse assembly GO:0007416 143 0.359
small gtpase mediated signal transduction GO:0007264 88 0.358
ovarian follicle cell development GO:0030707 248 0.352
regulation of filopodium assembly GO:0051489 24 0.347
organelle assembly GO:0070925 198 0.337
epidermis development GO:0008544 65 0.331
phosphorylation GO:0016310 294 0.330
cellular protein modification process GO:0006464 438 0.330
Human Mouse
negative regulation of response to stimulus GO:0048585 258 0.324
branching morphogenesis of an epithelial tube GO:0048754 45 0.323
cell cell signaling involved in cell fate commitment GO:0045168 210 0.318
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.313
developmental growth GO:0048589 280 0.309
Mouse Worm
regulation of neurogenesis GO:0050767 158 0.308
Human
border follicle cell migration GO:0007298 113 0.308
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.305
cellular catabolic process GO:0044248 372 0.304
wound healing GO:0042060 75 0.303
synaptic growth at neuromuscular junction GO:0051124 119 0.290
single organismal cell cell adhesion GO:0016337 45 0.284
Human
photoreceptor cell development GO:0042461 96 0.284
gastrulation with mouth forming first GO:0001703 36 0.279
wnt signaling pathway GO:0016055 98 0.276
response to fungus GO:0009620 50 0.274
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.274
axon extension involved in axon guidance GO:0048846 10 0.273
cellular response to chemical stimulus GO:0070887 199 0.271
columnar cuboidal epithelial cell development GO:0002066 249 0.268
gland morphogenesis GO:0022612 145 0.265
response to extracellular stimulus GO:0009991 116 0.264
regulation of synapse structure and activity GO:0050803 128 0.261
unidimensional cell growth GO:0009826 15 0.258
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.255
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.254
blastoderm segmentation GO:0007350 159 0.251
regulation of cellular protein metabolic process GO:0032268 243 0.250
Human Mouse
nucleus localization GO:0051647 34 0.247
epidermal cell differentiation GO:0009913 51 0.245
regulation of programmed cell death GO:0043067 152 0.242
regulation of cellular catabolic process GO:0031329 157 0.238
regulation of cell morphogenesis GO:0022604 163 0.229
regulation of transport GO:0051049 181 0.228
cell maturation GO:0048469 144 0.228
appendage morphogenesis GO:0035107 397 0.224
developmental programmed cell death GO:0010623 138 0.223
positive regulation of macromolecule metabolic process GO:0010604 405 0.223
Human Mouse
positive regulation of phosphorylation GO:0042327 87 0.222
Human Mouse
regulation of cellular localization GO:0060341 136 0.222
regulation of catalytic activity GO:0050790 185 0.222
Human Mouse
humoral immune response GO:0006959 117 0.218
nucleocytoplasmic transport GO:0006913 72 0.217
regulation of notch signaling pathway GO:0008593 100 0.216
negative regulation of developmental process GO:0051093 201 0.216
multi organism behavior GO:0051705 175 0.215
cell proliferation GO:0008283 299 0.213
Mouse
dorsal closure elongation of leading edge cells GO:0007394 10 0.207
epithelial cell migration GO:0010631 148 0.206
regulation of nervous system development GO:0051960 248 0.205
Human
actin filament polymerization GO:0030041 27 0.205
segmentation GO:0035282 207 0.204
gland development GO:0048732 191 0.203
regulation of apoptotic process GO:0042981 130 0.201
protein phosphorylation GO:0006468 169 0.199
Human Mouse
nuclear division GO:0000280 332 0.199
exocrine system development GO:0035272 162 0.198
regulation of protein localization GO:0032880 76 0.197
endocytosis GO:0006897 310 0.195
Worm
dendrite self avoidance GO:0070593 8 0.194
positive regulation of cellular protein metabolic process GO:0032270 118 0.193
Human Mouse
compound eye retinal cell programmed cell death GO:0046667 23 0.190
axis specification GO:0009798 167 0.188
body morphogenesis GO:0010171 2 0.185
Worm
death GO:0016265 284 0.185
positive regulation of protein kinase activity GO:0045860 25 0.184
Human Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.184
antimicrobial humoral response GO:0019730 99 0.182
cellular component assembly involved in morphogenesis GO:0010927 151 0.178
adherens junction organization GO:0034332 27 0.177
micropyle formation GO:0046844 4 0.176
regulation of phosphorylation GO:0042325 147 0.175
Human Mouse
dendrite morphogenesis GO:0048813 199 0.171
Human
spermatid differentiation GO:0048515 114 0.170
regulation of lamellipodium organization GO:1902743 15 0.169
regulation of response to wounding GO:1903034 19 0.168
regulation of anatomical structure morphogenesis GO:0022603 242 0.166
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.163
phagocytosis GO:0006909 215 0.161
ameboidal type cell migration GO:0001667 151 0.160
cell adhesion GO:0007155 136 0.160
Human
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.157
cytoplasmic transport GO:0016482 130 0.155
open tracheal system development GO:0007424 204 0.155
establishment of protein localization GO:0045184 163 0.154
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.154
vesicle mediated transport GO:0016192 381 0.152
Worm
response to starvation GO:0042594 97 0.146
positive regulation of catalytic activity GO:0043085 118 0.145
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.145
signal transduction by phosphorylation GO:0023014 107 0.144
imaginal disc fusion GO:0046528 19 0.141
apoptotic cell clearance GO:0043277 14 0.140
apoptotic process GO:0006915 159 0.139
notch signaling pathway GO:0007219 120 0.139
intracellular signal transduction GO:0035556 300 0.138
positive regulation of filopodium assembly GO:0051491 15 0.135
regulation of organ morphogenesis GO:2000027 78 0.133
positive regulation of response to stimulus GO:0048584 323 0.133
Human Mouse
secretion by cell GO:0032940 101 0.133
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.132
regulation of protein phosphorylation GO:0001932 64 0.132
Human Mouse
cytokinesis GO:0000910 90 0.131
immune response regulating signaling pathway GO:0002764 2 0.130
regulation of multi organism process GO:0043900 131 0.129
regulation of dendrite morphogenesis GO:0048814 28 0.127
Human
negative regulation of cellular protein metabolic process GO:0032269 85 0.125
asymmetric neuroblast division GO:0055059 33 0.124
positive regulation of mapk cascade GO:0043410 63 0.123
Human Mouse
microtubule based movement GO:0007018 51 0.123
imaginal disc derived wing hair site selection GO:0035320 4 0.122
regulation of molecular function GO:0065009 217 0.122
Human Mouse
negative regulation of protein phosphorylation GO:0001933 17 0.121
organic substance transport GO:0071702 257 0.121
melanin metabolic process GO:0006582 47 0.120
smad protein import into nucleus GO:0007184 11 0.118
regulation of actin filament length GO:0030832 27 0.118
regulation of actin filament bundle assembly GO:0032231 8 0.116
regulation of establishment of planar polarity GO:0090175 22 0.116
muscle structure development GO:0061061 224 0.115
cell growth GO:0016049 108 0.114
Worm
neuron projection extension GO:1990138 32 0.113
Worm
regulation of hydrolase activity GO:0051336 97 0.113
positive regulation of phosphorus metabolic process GO:0010562 139 0.112
Human Mouse
actin polymerization or depolymerization GO:0008154 31 0.112
positive regulation of endopeptidase activity GO:0010950 26 0.112
embryonic pattern specification GO:0009880 174 0.110
regulation of organelle organization GO:0033043 196 0.109
organic substance catabolic process GO:1901575 308 0.108
regulation of axon extension involved in axon guidance GO:0048841 4 0.105
lamellipodium organization GO:0097581 21 0.104
stem cell development GO:0048864 79 0.104
neurological system process GO:0050877 358 0.104
single organism cell adhesion GO:0098602 47 0.103
Human
enzyme linked receptor protein signaling pathway GO:0007167 179 0.103
circulatory system development GO:0072359 82 0.103
neuroblast division GO:0055057 35 0.103
cell cell adhesion GO:0098609 26 0.102
positive regulation of cellular catabolic process GO:0031331 95 0.102
hemocyte migration GO:0035099 19 0.102
developmental maturation GO:0021700 172 0.102
regulation of locomotion GO:0040012 42 0.102
Human
maintenance of cell polarity GO:0030011 18 0.101
germ line cyst formation GO:0048134 44 0.100
filopodium assembly GO:0046847 33 0.100
response to light stimulus GO:0009416 124 0.100
positive regulation of transcription dna templated GO:0045893 266 0.100
protein transport GO:0015031 155 0.099
anterior posterior axis specification embryo GO:0008595 103 0.098
cell cell junction assembly GO:0007043 38 0.096
positive regulation of biosynthetic process GO:0009891 316 0.096
negative regulation of catalytic activity GO:0043086 42 0.096
cellular protein localization GO:0034613 160 0.095
positive regulation of peptidase activity GO:0010952 29 0.094
branching involved in open tracheal system development GO:0060446 45 0.094
positive regulation of cellular biosynthetic process GO:0031328 316 0.093
dephosphorylation GO:0016311 51 0.093
regulation of immune response GO:0050776 118 0.092
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.092
cardiovascular system development GO:0072358 82 0.092
positive regulation of proteolysis GO:0045862 52 0.091
single organism intracellular transport GO:1902582 207 0.091
compound eye photoreceptor fate commitment GO:0001752 36 0.091
negative regulation of phosphorus metabolic process GO:0010563 45 0.091
epidermal growth factor receptor signaling pathway GO:0007173 58 0.089
negative regulation of signaling GO:0023057 219 0.088
organelle fission GO:0048285 340 0.088
maternal determination of anterior posterior axis embryo GO:0008358 74 0.087
maintenance of protein location GO:0045185 28 0.087
salivary gland development GO:0007431 162 0.087
tissue death GO:0016271 102 0.086
dorsal closure spreading of leading edge cells GO:0007395 4 0.086
r7 cell differentiation GO:0045466 43 0.085
regionalization GO:0003002 416 0.083
intracellular protein transport GO:0006886 104 0.083
cortical actin cytoskeleton organization GO:0030866 24 0.083
positive regulation of catabolic process GO:0009896 105 0.082
growth GO:0040007 359 0.082
Mouse Worm
negative regulation of protein metabolic process GO:0051248 85 0.082
multi multicellular organism process GO:0044706 123 0.082
Mouse
ventral furrow formation GO:0007370 17 0.081
response to biotic stimulus GO:0009607 294 0.081
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.081
regulation of embryonic cell shape GO:0016476 30 0.079
positive regulation of cell migration GO:0030335 2 0.079
positive regulation of cell communication GO:0010647 250 0.079
Human Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.078
regulation of rho protein signal transduction GO:0035023 20 0.078
purine ribonucleoside metabolic process GO:0046128 127 0.077
regulation of protein serine threonine kinase activity GO:0071900 25 0.077
Human Mouse
positive regulation of protein phosphorylation GO:0001934 34 0.076
Human Mouse
regulation of vesicle mediated transport GO:0060627 59 0.076
asymmetric protein localization GO:0008105 33 0.076
regulation of cell cell adhesion GO:0022407 21 0.076
Human
regulation of response to stress GO:0080134 200 0.075
Human Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.075
axonal fasciculation GO:0007413 12 0.075
membrane organization GO:0061024 112 0.074
glial cell migration GO:0008347 31 0.073
synaptic transmission GO:0007268 288 0.073
organelle localization GO:0051640 148 0.072
response to external biotic stimulus GO:0043207 293 0.070
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.070
regulation of developmental growth GO:0048638 174 0.069
Mouse
dorsal appendage formation GO:0046843 47 0.069
establishment of protein localization to organelle GO:0072594 62 0.069
cation transport GO:0006812 110 0.069
positive regulation of intracellular signal transduction GO:1902533 116 0.069
Human Mouse
regulation of execution phase of apoptosis GO:1900117 5 0.068
ectodermal digestive tract morphogenesis GO:0048567 7 0.068
positive regulation of rna biosynthetic process GO:1902680 266 0.068
regulation of mitotic cell cycle GO:0007346 190 0.068
establishment of cell polarity GO:0030010 40 0.067
positive regulation of cell projection organization GO:0031346 29 0.067
hematopoietic or lymphoid organ development GO:0048534 57 0.067
Mouse
regulation of immune effector process GO:0002697 52 0.066
regulation of ras protein signal transduction GO:0046578 93 0.066
extrinsic apoptotic signaling pathway GO:0097191 1 0.066
lateral inhibition GO:0046331 206 0.065
instar larval development GO:0002168 55 0.064
anterior midgut ectodermal morphogenesis GO:0007441 4 0.064
salivary gland morphogenesis GO:0007435 145 0.064
protein polymerization GO:0051258 42 0.064
negative regulation of apoptotic process GO:0043066 63 0.064
negative regulation of cell cycle GO:0045786 116 0.063
cell division GO:0051301 248 0.063
positive regulation of signaling GO:0023056 243 0.063
Human Mouse
autophagy GO:0006914 108 0.062
glycosyl compound catabolic process GO:1901658 112 0.061
response to organic substance GO:0010033 284 0.061
positive regulation of signal transduction GO:0009967 223 0.060
Human Mouse
regulation of protein modification process GO:0031399 112 0.060
Human Mouse
somatic stem cell division GO:0048103 37 0.060
malpighian tubule development GO:0072002 64 0.060
axis elongation GO:0003401 3 0.059
regulation of proteolysis GO:0030162 87 0.058
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.057
negative regulation of growth GO:0045926 84 0.057
mitotic nuclear division GO:0007067 213 0.057
protein localization to organelle GO:0033365 82 0.057
maintenance of location GO:0051235 73 0.056
Worm
epithelium migration GO:0090132 148 0.056
regulation of cell motility GO:2000145 23 0.055
Human
regulation of cell shape GO:0008360 113 0.055
anterior posterior pattern specification GO:0009952 136 0.055
spermatid development GO:0007286 98 0.054
germarium derived female germ line cyst formation GO:0030727 42 0.054
regulation of wnt signaling pathway GO:0030111 68 0.054
axon extension GO:0048675 32 0.053
Worm
ion transport GO:0006811 145 0.053
head development GO:0060322 135 0.053
regulation of mapk cascade GO:0043408 92 0.052
Human Mouse
secretion GO:0046903 109 0.052
epithelial cell cell adhesion GO:0090136 6 0.052
axon regeneration GO:0031103 8 0.051
collateral sprouting GO:0048668 3 0.051
dorsal closure amnioserosa morphology change GO:0046664 7 0.051
activation of jun kinase activity GO:0007257 3 0.051
Human Mouse
negative regulation of cell cycle process GO:0010948 109 0.051
protein targeting to nucleus GO:0044744 51 0.051
imaginal disc derived leg morphogenesis GO:0007480 80 0.051
negative regulation of cell differentiation GO:0045596 143 0.050
stress activated protein kinase signaling cascade GO:0031098 55 0.049
heterocycle catabolic process GO:0046700 166 0.049
regulation of jnk cascade GO:0046328 40 0.049
Human Mouse
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.048
cellular response to oxygen containing compound GO:1901701 79 0.048
melanization defense response GO:0035006 45 0.048
positive regulation of cytoskeleton organization GO:0051495 21 0.048
cellular response to arsenic containing substance GO:0071243 6 0.048
ovarian follicle cell migration GO:0007297 121 0.048
lipid localization GO:0010876 54 0.047
Worm
negative regulation of phosphate metabolic process GO:0045936 45 0.046
mesoderm development GO:0007498 78 0.046
renal system development GO:0072001 72 0.045
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.045
positive regulation of actin filament polymerization GO:0030838 11 0.045
negative regulation of mitotic cell cycle GO:0045930 109 0.045
oocyte microtubule cytoskeleton organization GO:0016325 35 0.045
morphogenesis of follicular epithelium GO:0016333 36 0.044
spindle organization GO:0007051 253 0.044
regulation of apoptotic signaling pathway GO:2001233 10 0.044
histolysis GO:0007559 102 0.043
regulation of synapse organization GO:0050807 110 0.043
regulation of cellular component movement GO:0051270 42 0.043
Human
centrosome organization GO:0051297 163 0.043
proteolysis GO:0006508 192 0.043
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.043
eggshell formation GO:0030703 105 0.043
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.043
lipid metabolic process GO:0006629 121 0.042
negative regulation of cellular component organization GO:0051129 108 0.042
regulation of axon extension GO:0030516 8 0.042
female germ line cyst formation GO:0048135 42 0.042
protein import into nucleus GO:0006606 51 0.042
erbb signaling pathway GO:0038127 58 0.041
hemopoiesis GO:0030097 46 0.041
Mouse
cell cycle phase transition GO:0044770 140 0.040
semaphorin plexin signaling pathway GO:0071526 4 0.040
substrate dependent cell migration GO:0006929 3 0.040
regulation of cellular component biogenesis GO:0044087 201 0.039
apical constriction involved in gastrulation GO:0003384 7 0.039
macroautophagy GO:0016236 42 0.039
regulation of protein transport GO:0051223 57 0.039
cellularization GO:0007349 90 0.038
cellular macromolecule catabolic process GO:0044265 136 0.038
nucleoside triphosphate catabolic process GO:0009143 108 0.038
negative regulation of molecular function GO:0044092 51 0.038
positive regulation of immune response GO:0050778 63 0.038
central nervous system development GO:0007417 201 0.038
macromolecule catabolic process GO:0009057 161 0.037
developmental cell growth GO:0048588 52 0.036
Worm
ribonucleoside catabolic process GO:0042454 112 0.036
cellular response to peptide hormone stimulus GO:0071375 28 0.036
sex differentiation GO:0007548 81 0.036
Worm
regulation of multicellular organismal development GO:2000026 414 0.036
mitotic cell cycle phase transition GO:0044772 138 0.036
cellular response to organic substance GO:0071310 132 0.035
positive regulation of hydrolase activity GO:0051345 78 0.035
single organism nuclear import GO:1902593 51 0.035
regulation of cell adhesion GO:0030155 27 0.035
Human
neuron fate commitment GO:0048663 50 0.035
response to virus GO:0009615 28 0.035
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.035
regulation of developmental pigmentation GO:0048070 24 0.035
regulation of behavior GO:0050795 75 0.035
dendrite development GO:0016358 204 0.035
Human
establishment of protein localization to plasma membrane GO:0090002 9 0.034
nuclear import GO:0051170 51 0.034
peripheral nervous system development GO:0007422 52 0.034
neurotransmitter transport GO:0006836 37 0.033
exocytosis GO:0006887 28 0.033
reproductive behavior GO:0019098 122 0.033
heart development GO:0007507 82 0.033
organophosphate metabolic process GO:0019637 195 0.032
nuclear transport GO:0051169 72 0.032
regulation of jun kinase activity GO:0043506 8 0.032
Human Mouse
regulation of rho gtpase activity GO:0032319 20 0.032
protein dephosphorylation GO:0006470 27 0.032
protein localization to nucleus GO:0034504 55 0.032
small molecule metabolic process GO:0044281 305 0.032
regulation of kinase activity GO:0043549 53 0.032
Human Mouse
cilium morphogenesis GO:0060271 39 0.031
single organism membrane organization GO:0044802 93 0.031
stem cell differentiation GO:0048863 117 0.031
positive regulation of transport GO:0051050 92 0.031
regulation of cell proliferation GO:0042127 163 0.031
Mouse
cellular lipid metabolic process GO:0044255 83 0.031
negative regulation of wnt signaling pathway GO:0030178 28 0.031
purine containing compound metabolic process GO:0072521 155 0.030
regulation of response to biotic stimulus GO:0002831 63 0.030
larval development GO:0002164 104 0.030
Worm
positive regulation of phosphate metabolic process GO:0045937 139 0.030
Human Mouse
defense response to fungus GO:0050832 48 0.029
negative regulation of kinase activity GO:0033673 16 0.029

msn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org