Drosophila melanogaster

93 known processes

ns2 (Dmel_CG6501)

nucleostemin 2

(Aliases: Dmel\CG6501,dmNS2,CG6501,Ngp1,Ngp,NS2)

ns2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 147 0.308
rna splicing GO:0008380 83 0.219
negative regulation of gene expression GO:0010629 387 0.186
appendage development GO:0048736 401 0.157
regulation of multi organism process GO:0043900 131 0.142
negative regulation of signal transduction GO:0009968 206 0.141
endocytosis GO:0006897 310 0.127
negative regulation of cell communication GO:0010648 223 0.127
catabolic process GO:0009056 409 0.110
appendage morphogenesis GO:0035107 397 0.108
regulation of cellular component biogenesis GO:0044087 201 0.108
rna catabolic process GO:0006401 37 0.102
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.089
negative regulation of biosynthetic process GO:0009890 277 0.086
nucleobase containing compound catabolic process GO:0034655 165 0.085
regulation of apoptotic process GO:0042981 130 0.084
stem cell development GO:0048864 79 0.083
negative regulation of response to stimulus GO:0048585 258 0.083
protein modification process GO:0036211 438 0.077
positive regulation of rna metabolic process GO:0051254 271 0.073
negative regulation of cellular biosynthetic process GO:0031327 277 0.068
axon guidance GO:0007411 233 0.067
cell cycle phase transition GO:0044770 140 0.066
regulation of mitotic cell cycle phase transition GO:1901990 130 0.066
regulation of cell death GO:0010941 173 0.065
chemical homeostasis GO:0048878 92 0.065
positive regulation of cellular biosynthetic process GO:0031328 316 0.064
imaginal disc derived appendage development GO:0048737 399 0.062
stem cell differentiation GO:0048863 117 0.062
cellular macromolecule catabolic process GO:0044265 136 0.060
positive regulation of rna biosynthetic process GO:1902680 266 0.059
negative regulation of signaling GO:0023057 219 0.058
regulation of mitotic cell cycle GO:0007346 190 0.056
regulation of cell cycle GO:0051726 291 0.055
regulation of cell differentiation GO:0045595 302 0.055
regulation of gene expression epigenetic GO:0040029 128 0.054
morphogenesis of an epithelium GO:0002009 276 0.054
cellular catabolic process GO:0044248 372 0.054
negative regulation of cell differentiation GO:0045596 143 0.054
wing disc morphogenesis GO:0007472 344 0.054
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.054
mrna catabolic process GO:0006402 33 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.052
positive regulation of signaling GO:0023056 243 0.051
immune response GO:0006955 246 0.051
negative regulation of nucleic acid templated transcription GO:1903507 240 0.050
cellular protein modification process GO:0006464 438 0.050
positive regulation of nucleic acid templated transcription GO:1903508 266 0.049
protein complex biogenesis GO:0070271 201 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.048
mrna metabolic process GO:0016071 124 0.047
protein localization GO:0008104 284 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.045
regulation of multicellular organismal development GO:2000026 414 0.045
negative regulation of transcription dna templated GO:0045892 237 0.044
rrna processing GO:0006364 3 0.044
death GO:0016265 284 0.044
cytoskeleton dependent cytokinesis GO:0061640 81 0.044
macromolecule catabolic process GO:0009057 161 0.043
developmental growth GO:0048589 280 0.042
mitotic cytokinesis GO:0000281 50 0.042
cell death GO:0008219 279 0.041
negative regulation of developmental process GO:0051093 201 0.041
ncrna metabolic process GO:0034660 43 0.041
salivary gland development GO:0007431 162 0.041
regulation of proteolysis GO:0030162 87 0.041
programmed cell death GO:0012501 257 0.040
exocrine system development GO:0035272 162 0.040
negative regulation of rna biosynthetic process GO:1902679 240 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.040
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.039
positive regulation of endopeptidase activity GO:0010950 26 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.039
regulation of programmed cell death GO:0043067 152 0.039
multi organism behavior GO:0051705 175 0.038
regulation of developmental growth GO:0048638 174 0.038
regulation of cell cycle process GO:0010564 181 0.037
macromolecular complex assembly GO:0065003 256 0.037
apoptotic process involved in development GO:1902742 20 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
protein complex assembly GO:0006461 200 0.037
organelle localization GO:0051640 148 0.037
protein modification by small protein conjugation or removal GO:0070647 106 0.036
organonitrogen compound metabolic process GO:1901564 318 0.036
imaginal disc derived appendage morphogenesis GO:0035114 395 0.036
mitotic cell cycle phase transition GO:0044772 138 0.035
columnar cuboidal epithelial cell development GO:0002066 249 0.035
regulation of wnt signaling pathway GO:0030111 68 0.035
nucleocytoplasmic transport GO:0006913 72 0.035
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.035
proteolysis GO:0006508 192 0.034
nuclear transport GO:0051169 72 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.033
intracellular signal transduction GO:0035556 300 0.033
regionalization GO:0003002 416 0.033
cellular macromolecular complex assembly GO:0034622 153 0.033
neuron projection guidance GO:0097485 241 0.033
salivary gland morphogenesis GO:0007435 145 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
mrna processing GO:0006397 104 0.032
regulation of cell development GO:0060284 215 0.032
protein modification by small protein conjugation GO:0032446 79 0.032
regulation of response to stress GO:0080134 200 0.032
regulation of transport GO:0051049 181 0.031
gland development GO:0048732 191 0.031
mesenchymal cell differentiation GO:0048762 1 0.031
nuclear import GO:0051170 51 0.031
regulation of cell proliferation GO:0042127 163 0.031
establishment of localization in cell GO:0051649 402 0.031
nuclear division GO:0000280 332 0.031
aging GO:0007568 143 0.030
regulation of defense response GO:0031347 102 0.030
axon development GO:0061564 297 0.030
defense response GO:0006952 300 0.030
positive regulation of cell communication GO:0010647 250 0.030
immune system process GO:0002376 347 0.030
ribosomal large subunit biogenesis GO:0042273 1 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
dendrite morphogenesis GO:0048813 199 0.028
heterocycle catabolic process GO:0046700 166 0.028
apoptotic process GO:0006915 159 0.028
intracellular transport GO:0046907 228 0.028
sodium dependent phosphate transport GO:0044341 2 0.028
oviposition GO:0018991 19 0.027
purine containing compound metabolic process GO:0072521 155 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
regulation of innate immune response GO:0045088 71 0.027
chromatin silencing GO:0006342 76 0.027
cell migration GO:0016477 238 0.027
nucleosome assembly GO:0006334 35 0.027
response to other organism GO:0051707 293 0.026
negative regulation of cell cycle phase transition GO:1901988 103 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.026
organic acid metabolic process GO:0006082 103 0.026
protein maturation GO:0051604 71 0.026
positive regulation of signal transduction GO:0009967 223 0.026
mitotic g2 m transition checkpoint GO:0044818 70 0.026
cellular protein localization GO:0034613 160 0.026
regulation of catabolic process GO:0009894 170 0.026
positive regulation of stem cell differentiation GO:2000738 3 0.026
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.025
multicellular organismal reproductive behavior GO:0033057 110 0.025
organophosphate metabolic process GO:0019637 195 0.025
regulation of localization GO:0032879 275 0.025
positive regulation of transcription dna templated GO:0045893 266 0.024
response to ionizing radiation GO:0010212 32 0.024
body morphogenesis GO:0010171 2 0.024
chromatin assembly or disassembly GO:0006333 52 0.024
regulation of endopeptidase activity GO:0052548 36 0.024
positive regulation of gene expression GO:0010628 290 0.024
stem cell maintenance GO:0019827 67 0.024
multi multicellular organism process GO:0044706 123 0.024
regulation of response to biotic stimulus GO:0002831 63 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
regulation of cellular localization GO:0060341 136 0.023
negative regulation of cellular catabolic process GO:0031330 34 0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
negative regulation of apoptotic process GO:0043066 63 0.023
mesenchymal cell development GO:0014031 1 0.023
cell division GO:0051301 248 0.023
photoreceptor cell differentiation GO:0046530 170 0.023
single organism behavior GO:0044708 391 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
regulation of protein localization GO:0032880 76 0.022
response to organic substance GO:0010033 284 0.022
single organism intracellular transport GO:1902582 207 0.022
tissue morphogenesis GO:0048729 297 0.022
regulation of organ morphogenesis GO:2000027 78 0.022
regulation of reproductive process GO:2000241 54 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
determination of adult lifespan GO:0008340 137 0.021
axonogenesis GO:0007409 290 0.021
chromosome organization GO:0051276 360 0.021
regulation of protein transport GO:0051223 57 0.021
negative regulation of cell cycle GO:0045786 116 0.021
localization of cell GO:0051674 257 0.020
vesicle mediated transport GO:0016192 381 0.020
cytoplasmic transport GO:0016482 130 0.020
mitotic dna damage checkpoint GO:0044773 74 0.020
cellular amide metabolic process GO:0043603 80 0.020
negative regulation of mitotic cell cycle GO:0045930 109 0.020
protein transport GO:0015031 155 0.019
spindle organization GO:0007051 253 0.019
cell motility GO:0048870 251 0.019
homeostatic process GO:0042592 199 0.019
regulation of synapse structure and activity GO:0050803 128 0.019
positive regulation of developmental process GO:0051094 143 0.019
cellular response to ionizing radiation GO:0071479 15 0.019
regulation of cell division GO:0051302 72 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
central nervous system development GO:0007417 201 0.019
small molecule metabolic process GO:0044281 305 0.019
meiotic cell cycle GO:0051321 171 0.019
histolysis GO:0007559 102 0.019
cytokinesis GO:0000910 90 0.019
cellular response to organic substance GO:0071310 132 0.019
growth GO:0040007 359 0.018
camera type eye development GO:0043010 4 0.018
adult behavior GO:0030534 137 0.018
regulation of response to nutrient levels GO:0032107 18 0.018
cell cycle checkpoint GO:0000075 95 0.018
negative regulation of programmed cell death GO:0043069 72 0.018
regulation of nervous system development GO:0051960 248 0.018
organic substance transport GO:0071702 257 0.018
sister chromatid segregation GO:0000819 92 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
protein catabolic process GO:0030163 101 0.018
regulation of catalytic activity GO:0050790 185 0.018
protein processing GO:0016485 68 0.018
ribonucleoprotein complex biogenesis GO:0022613 31 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
forebrain development GO:0030900 2 0.017
gland morphogenesis GO:0022612 145 0.017
segmentation GO:0035282 207 0.017
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.017
bmp signaling pathway GO:0030509 27 0.017
dendrite development GO:0016358 204 0.017
gene silencing GO:0016458 138 0.017
chromatin organization GO:0006325 207 0.017
regulation of response to external stimulus GO:0032101 115 0.017
phagocytosis GO:0006909 215 0.017
positive regulation of developmental growth GO:0048639 62 0.017
cell type specific apoptotic process GO:0097285 38 0.017
tissue death GO:0016271 102 0.016
skeletal muscle fiber development GO:0048741 3 0.016
establishment of protein localization GO:0045184 163 0.016
synapse organization GO:0050808 196 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
nurse cell apoptotic process GO:0045476 17 0.016
synapse assembly GO:0007416 143 0.016
establishment of organelle localization GO:0051656 122 0.016
tissue migration GO:0090130 155 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
regulation of cellular protein catabolic process GO:1903362 44 0.016
cellular macromolecule localization GO:0070727 220 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
regulation of gene silencing GO:0060968 63 0.016
regulation of epithelial cell proliferation GO:0050678 4 0.016
organic substance catabolic process GO:1901575 308 0.015
response to bacterium GO:0009617 198 0.015
defense response to bacterium GO:0042742 178 0.015
hemopoiesis GO:0030097 46 0.015
blastoderm segmentation GO:0007350 159 0.015
epithelial cell differentiation GO:0030855 322 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.015
g2 m transition of mitotic cell cycle GO:0000086 19 0.015
regulation of cellular response to stress GO:0080135 89 0.015
lipid homeostasis GO:0055088 33 0.015
nephron development GO:0072006 3 0.015
negative regulation of response to external stimulus GO:0032102 22 0.015
eye pigmentation GO:0048069 43 0.015
mitotic nuclear division GO:0007067 213 0.015
dna metabolic process GO:0006259 227 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
branch fusion open tracheal system GO:0035147 17 0.015
regulation of hydrolase activity GO:0051336 97 0.015
regulation of malpighian tubule diameter GO:0035297 3 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
regulation of organelle organization GO:0033043 196 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
epithelial cell migration GO:0010631 148 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.014
dna damage checkpoint GO:0000077 78 0.014
neuromuscular synaptic transmission GO:0007274 67 0.014
epithelium migration GO:0090132 148 0.014
protein acylation GO:0043543 42 0.014
regulation of protein complex disassembly GO:0043244 29 0.013
nephron epithelium morphogenesis GO:0072088 3 0.013
regulation of nuclear division GO:0051783 58 0.013
ovarian follicle cell migration GO:0007297 121 0.013
synaptic transmission GO:0007268 288 0.013
regulation of peptidase activity GO:0052547 39 0.013
compound eye development GO:0048749 307 0.013
developmental programmed cell death GO:0010623 138 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.013
connective tissue development GO:0061448 3 0.013
protein import GO:0017038 55 0.013
intracellular protein transport GO:0006886 104 0.013
response to abiotic stimulus GO:0009628 341 0.013
ovarian follicle cell development GO:0030707 248 0.013
sex differentiation GO:0007548 81 0.013
innate immune response GO:0045087 144 0.013
protein ubiquitination GO:0016567 70 0.013
positive regulation of multicellular organism growth GO:0040018 21 0.012
spinal cord development GO:0021510 1 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
negative regulation of defense response GO:0031348 35 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
defense response to other organism GO:0098542 225 0.012
telencephalon development GO:0021537 2 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
negative regulation of autophagy GO:0010507 16 0.012
kidney epithelium development GO:0072073 3 0.012
regulation of dna metabolic process GO:0051052 34 0.012
negative regulation of growth GO:0045926 84 0.012
regulation of neurogenesis GO:0050767 158 0.012
rna localization GO:0006403 115 0.012
morphogenesis of follicular epithelium GO:0016333 36 0.012
retina development in camera type eye GO:0060041 4 0.012
tube morphogenesis GO:0035239 191 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
multicellular organism growth GO:0035264 46 0.012
regulation of response to extracellular stimulus GO:0032104 18 0.012
response to endogenous stimulus GO:0009719 119 0.012
protein targeting to nucleus GO:0044744 51 0.012
negative regulation of transcription regulatory region dna binding GO:2000678 3 0.012
chromatin modification GO:0016568 147 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.012
regulation of cellular response to growth factor stimulus GO:0090287 13 0.012
oocyte axis specification GO:0007309 108 0.012
mitotic sister chromatid segregation GO:0000070 87 0.011
regulation of molecular function GO:0065009 217 0.011
open tracheal system development GO:0007424 204 0.011
negative regulation of molecular function GO:0044092 51 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.011
cell growth GO:0016049 108 0.011
kidney development GO:0001822 3 0.011
compound eye morphogenesis GO:0001745 249 0.011
ras protein signal transduction GO:0007265 88 0.011
dna packaging GO:0006323 91 0.011
organelle fission GO:0048285 340 0.011
regulation of bmp signaling pathway GO:0030510 23 0.011
lipid localization GO:0010876 54 0.011
mitotic spindle organization GO:0007052 220 0.011
macromolecular complex disassembly GO:0032984 37 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
pole plasm oskar mrna localization GO:0045451 46 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
regulation of chromatin silencing GO:0031935 36 0.011
negative regulation of cell death GO:0060548 81 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
dna conformation change GO:0071103 105 0.011
multi organism reproductive behavior GO:0044705 121 0.011
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
meiosis ii GO:0007135 23 0.010
inter male aggressive behavior GO:0002121 60 0.010
cellular response to external stimulus GO:0071496 66 0.010
axis specification GO:0009798 167 0.010
negative regulation of catabolic process GO:0009895 36 0.010
regulation of nucleocytoplasmic transport GO:0046822 35 0.010
cellular response to gamma radiation GO:0071480 10 0.010
antimicrobial peptide biosynthetic process GO:0002777 38 0.010
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.010
histone exchange GO:0043486 21 0.010
response to glucose GO:0009749 2 0.010
larval development GO:0002164 104 0.010
male gamete generation GO:0048232 201 0.010
gastrulation GO:0007369 70 0.010

ns2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
central nervous system disease DOID:331 0 0.023
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
organ system cancer DOID:0050686 0 0.022
neurodegenerative disease DOID:1289 0 0.011
musculoskeletal system cancer DOID:0060100 0 0.010