Drosophila melanogaster

202 known processes

esg (Dmel_CG3758)

escargot

(Aliases: Dmel\CG3758,l(2)4B7,4B7,br43,Esg,wiz,l(2)35Ce,l(2)br43,dgl,shof,BG:DS07851.7,l35Ce,l(2)esg,CG3758,flg,l(2)07082)

esg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
respiratory system development GO:0060541 213 0.996
cell migration GO:0016477 238 0.980
cell motility GO:0048870 251 0.977
brain development GO:0007420 120 0.961
central nervous system development GO:0007417 201 0.955
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.948
open tracheal system development GO:0007424 204 0.937
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.923
eye morphogenesis GO:0048592 260 0.907
malpighian tubule morphogenesis GO:0007443 44 0.903
Fly
eye development GO:0001654 323 0.894
Fly
compound eye development GO:0048749 307 0.888
Fly
epithelial cell migration open tracheal system GO:0007427 32 0.888
photoreceptor cell differentiation GO:0046530 170 0.886
eye photoreceptor cell differentiation GO:0001754 145 0.855
cell cell signaling involved in cell fate commitment GO:0045168 210 0.847
tube morphogenesis GO:0035239 191 0.838
embryonic morphogenesis GO:0048598 206 0.824
Zebrafish Mouse Fly
positive regulation of rna metabolic process GO:0051254 271 0.800
taxis GO:0042330 304 0.791
negative regulation of cellular biosynthetic process GO:0031327 277 0.787
neurological system process GO:0050877 358 0.783
Human Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.778
lateral inhibition GO:0046331 206 0.776
compound eye morphogenesis GO:0001745 249 0.765
stem cell proliferation GO:0072089 88 0.760
male gamete generation GO:0048232 201 0.757
negative regulation of rna metabolic process GO:0051253 251 0.735
dendrite morphogenesis GO:0048813 199 0.725
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.719
positive regulation of transcription dna templated GO:0045893 266 0.693
negative regulation of nucleic acid templated transcription GO:1903507 240 0.677
head development GO:0060322 135 0.675
transcription from rna polymerase ii promoter GO:0006366 368 0.663
r7 cell differentiation GO:0045466 43 0.629
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.629
positive regulation of nucleic acid templated transcription GO:1903508 266 0.620
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.577
negative regulation of gene expression GO:0010629 387 0.556
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.536
limb morphogenesis GO:0035108 1 0.535
regionalization GO:0003002 416 0.525
Zebrafish Mouse
axonogenesis GO:0007409 290 0.517
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.511
negative regulation of rna biosynthetic process GO:1902679 240 0.492
neuroblast proliferation GO:0007405 74 0.488
tube development GO:0035295 244 0.457
regulation of epithelial cell proliferation GO:0050678 4 0.456
Human
axon development GO:0061564 297 0.451
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.448
negative regulation of cellular metabolic process GO:0031324 382 0.447
spermatogenesis GO:0007283 200 0.428
cell proliferation GO:0008283 299 0.426
gastrulation GO:0007369 70 0.410
Zebrafish Mouse Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.404
Human Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.397
intracellular signal transduction GO:0035556 300 0.385
Human
axon guidance GO:0007411 233 0.383
negative regulation of response to stimulus GO:0048585 258 0.382
Human Mouse
regulation of immune system process GO:0002682 176 0.366
digestive tract morphogenesis GO:0048546 127 0.359
Zebrafish Mouse Fly
regulation of tube architecture open tracheal system GO:0035152 68 0.357
localization of cell GO:0051674 257 0.354
positive regulation of macromolecule metabolic process GO:0010604 405 0.325
single organism behavior GO:0044708 391 0.324
sensory organ morphogenesis GO:0090596 260 0.324
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.320
wing disc morphogenesis GO:0007472 344 0.320
mesoderm development GO:0007498 78 0.314
Zebrafish Mouse
tissue morphogenesis GO:0048729 297 0.308
appendage development GO:0048736 401 0.306
stem cell maintenance GO:0019827 67 0.306
positive regulation of biosynthetic process GO:0009891 316 0.304
developmental programmed cell death GO:0010623 138 0.303
embryo development ending in birth or egg hatching GO:0009792 152 0.302
Mouse
chitin based cuticle development GO:0040003 49 0.298
regulation of cell proliferation GO:0042127 163 0.296
Human Mouse
apoptotic process involved in morphogenesis GO:0060561 3 0.286
photoreceptor cell development GO:0042461 96 0.279
cellular protein modification process GO:0006464 438 0.270
Mouse Fly
negative regulation of biosynthetic process GO:0009890 277 0.267
immune system process GO:0002376 347 0.264
trachea development GO:0060438 29 0.263
positive regulation of rna biosynthetic process GO:1902680 266 0.259
digestive system development GO:0055123 149 0.253
Zebrafish Mouse Fly
compound eye photoreceptor development GO:0042051 78 0.250
regulation of r7 cell differentiation GO:0045676 15 0.249
regulation of nervous system development GO:0051960 248 0.249
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.247
olfactory behavior GO:0042048 97 0.242
molting cycle GO:0042303 56 0.239
Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.239
Mouse Fly
epidermis development GO:0008544 65 0.237
Mouse
cell fate determination GO:0001709 91 0.224
hindbrain development GO:0030902 2 0.220
mesenchyme development GO:0060485 9 0.215
Human Zebrafish Mouse
imaginal disc derived appendage development GO:0048737 399 0.212
biological adhesion GO:0022610 138 0.212
Human Zebrafish Mouse
positive regulation of gene expression GO:0010628 290 0.209
stem cell differentiation GO:0048863 117 0.204
cell fate specification GO:0001708 71 0.203
cell fate commitment involved in pattern specification GO:0060581 31 0.203
programmed cell death GO:0012501 257 0.197
Human Mouse
regulation of developmental growth GO:0048638 174 0.195
eye photoreceptor cell development GO:0042462 81 0.192
regulation of cell cycle process GO:0010564 181 0.189
establishment of planar polarity GO:0001736 87 0.178
camera type eye development GO:0043010 4 0.173
negative regulation of epithelial cell proliferation GO:0050680 4 0.171
Human
intracellular protein transport GO:0006886 104 0.169
Human
developmental growth GO:0048589 280 0.169
protein modification process GO:0036211 438 0.169
Mouse Fly
limb development GO:0060173 1 0.159
epithelial cell proliferation GO:0050673 15 0.153
Human
blastoderm segmentation GO:0007350 159 0.153
establishment or maintenance of cell polarity GO:0007163 167 0.153
regulation of glial cell differentiation GO:0045685 1 0.153
serotonin metabolic process GO:0042428 2 0.152
gliogenesis GO:0042063 80 0.151
homeostatic process GO:0042592 199 0.146
mushroom body development GO:0016319 70 0.146
larval development GO:0002164 104 0.137
fusion cell fate specification GO:0035156 4 0.136
cell death GO:0008219 279 0.134
Human Mouse
periodic partitioning GO:0007365 29 0.134
muscle organ development GO:0007517 127 0.133
Fly
asymmetric neuroblast division GO:0055059 33 0.132
pigmentation GO:0043473 75 0.132
chemotaxis GO:0006935 249 0.128
embryonic pattern specification GO:0009880 174 0.127
embryonic axis specification GO:0000578 107 0.127
regulation of organ morphogenesis GO:2000027 78 0.126
Mouse
dendrite development GO:0016358 204 0.125
Fly
branching involved in open tracheal system development GO:0060446 45 0.123
morphogenesis of an epithelium GO:0002009 276 0.120
small molecule metabolic process GO:0044281 305 0.118
Human
forebrain development GO:0030900 2 0.116
imaginal disc derived wing morphogenesis GO:0007476 337 0.116
nucleocytoplasmic transport GO:0006913 72 0.116
Human
morphogenesis of a polarized epithelium GO:0001738 93 0.113
chemosensory behavior GO:0007635 106 0.110
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.106
negative regulation of cell communication GO:0010648 223 0.104
Human Mouse
regulation of cell morphogenesis GO:0022604 163 0.102
Human Mouse
protein transport GO:0015031 155 0.100
Human
specification of organ identity GO:0010092 3 0.100
kidney morphogenesis GO:0060993 3 0.099
compound eye retinal cell programmed cell death GO:0046667 23 0.098
regulation of stem cell differentiation GO:2000736 14 0.098
Human Mouse
protein modification by small protein conjugation or removal GO:0070647 106 0.097
regulation of photoreceptor cell differentiation GO:0046532 34 0.097
nuclear transport GO:0051169 72 0.096
Human
mesodermal cell fate specification GO:0007501 2 0.094
developmental induction GO:0031128 3 0.094
equator specification GO:0045317 4 0.094
salivary gland morphogenesis GO:0007435 145 0.093
Mouse
segmentation GO:0035282 207 0.092
glial cell development GO:0021782 27 0.090
synapse assembly GO:0007416 143 0.089
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.089
embryonic development via the syncytial blastoderm GO:0001700 148 0.088
negative regulation of transcription dna templated GO:0045892 237 0.087
negative regulation of stem cell proliferation GO:2000647 30 0.087
Mouse
somatic stem cell division GO:0048103 37 0.087
proximal distal pattern formation GO:0009954 15 0.086
exocrine system development GO:0035272 162 0.086
Mouse
neuronal stem cell division GO:0036445 35 0.085
renal tubule development GO:0061326 64 0.085
Fly
protein phosphorylation GO:0006468 169 0.083
epithelial cell type specification open tracheal system GO:0035153 11 0.083
regulation of anatomical structure size GO:0090066 163 0.083
establishment of ommatidial planar polarity GO:0042067 49 0.082
negative regulation of cellular component organization GO:0051129 108 0.079
mesoderm morphogenesis GO:0048332 22 0.079
Zebrafish Mouse
genital disc development GO:0035215 44 0.078
skin development GO:0043588 65 0.078
Mouse
cell division GO:0051301 248 0.077
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.076
renal tubule morphogenesis GO:0061333 44 0.075
Fly
retina development in camera type eye GO:0060041 4 0.074
negative regulation of signal transduction GO:0009968 206 0.074
Human Mouse
nephron epithelium morphogenesis GO:0072088 3 0.074
developmental maturation GO:0021700 172 0.073
response to nutrient levels GO:0031667 114 0.073
Human
amine metabolic process GO:0009308 12 0.072
regulation of wnt signaling pathway GO:0030111 68 0.071
Human
cuticle development GO:0042335 86 0.070
camera type eye morphogenesis GO:0048593 2 0.070
single organismal cell cell adhesion GO:0016337 45 0.069
Human Zebrafish
ameboidal type cell migration GO:0001667 151 0.068
circulatory system development GO:0072359 82 0.067
Mouse
regulation of multicellular organismal development GO:2000026 414 0.066
Human Mouse
protein import into nucleus GO:0006606 51 0.065
Human
regulation of imaginal disc derived wing size GO:0044719 20 0.065
kidney development GO:0001822 3 0.065
digestive tract development GO:0048565 149 0.065
Zebrafish Mouse Fly
carbohydrate derivative metabolic process GO:1901135 217 0.064
establishment of protein localization to organelle GO:0072594 62 0.063
Human
nephron tubule morphogenesis GO:0072078 3 0.063
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.062
endoderm development GO:0007492 6 0.061
proteolysis GO:0006508 192 0.060
notch signaling pathway GO:0007219 120 0.059
Human Mouse
heart morphogenesis GO:0003007 32 0.058
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.058
neuroblast division GO:0055057 35 0.058
negative regulation of programmed cell death GO:0043069 72 0.057
Human Mouse
renal system development GO:0072001 72 0.057
Fly
spermatid development GO:0007286 98 0.057
sensory perception of sound GO:0007605 56 0.056
Human Mouse
chromosome organization GO:0051276 360 0.056
Mouse Fly
positive regulation of response to stimulus GO:0048584 323 0.055
negative regulation of developmental process GO:0051093 201 0.055
neural retina development GO:0003407 4 0.055
dna metabolic process GO:0006259 227 0.055
hindgut morphogenesis GO:0007442 58 0.054
Fly
glial cell differentiation GO:0010001 35 0.054
regulation of cell shape GO:0008360 113 0.054
organic substance transport GO:0071702 257 0.054
Human
urogenital system development GO:0001655 72 0.053
Fly
protein import GO:0017038 55 0.053
Human
regulation of cell death GO:0010941 173 0.052
Human Mouse
hair cell differentiation GO:0035315 47 0.052
mesenchymal cell differentiation GO:0048762 1 0.051
Human Zebrafish Mouse
eye photoreceptor cell fate commitment GO:0042706 37 0.051
ommatidial rotation GO:0016318 20 0.051
morphogenesis of embryonic epithelium GO:0016331 94 0.050
developmental growth involved in morphogenesis GO:0060560 65 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.050
embryonic epithelial tube formation GO:0001838 6 0.050
cellular homeostasis GO:0019725 80 0.050
negative regulation of multicellular organismal process GO:0051241 142 0.048
Human Mouse
tracheal outgrowth open tracheal system GO:0007426 18 0.048
negative regulation of dna endoreduplication GO:0032876 2 0.048
posttranscriptional regulation of gene expression GO:0010608 145 0.048
establishment of protein localization GO:0045184 163 0.048
Human
sensory organ precursor cell fate determination GO:0016360 19 0.048
gravitaxis GO:0042332 26 0.047
negative regulation of developmental growth GO:0048640 64 0.047
neuron projection guidance GO:0097485 241 0.046
peripheral nervous system development GO:0007422 52 0.046
regulation of growth GO:0040008 233 0.046
heart development GO:0007507 82 0.044
Mouse
sensory perception GO:0007600 196 0.044
Human Mouse
axis specification GO:0009798 167 0.044
imaginal disc derived wing vein specification GO:0007474 48 0.044
intracellular transport GO:0046907 228 0.044
Human
regulation of cell fate specification GO:0042659 27 0.044
neural precursor cell proliferation GO:0061351 75 0.043
negative regulation of canonical wnt signaling pathway GO:0090090 6 0.043
Human
epithelium migration GO:0090132 148 0.043
cell recognition GO:0008037 102 0.042
regulation of molecular function GO:0065009 217 0.042
heterocycle catabolic process GO:0046700 166 0.041
smoothened signaling pathway GO:0007224 49 0.041
establishment of tissue polarity GO:0007164 87 0.041
compound eye photoreceptor fate commitment GO:0001752 36 0.041
germ cell migration GO:0008354 43 0.040
death GO:0016265 284 0.040
Human Mouse
intracellular receptor signaling pathway GO:0030522 19 0.039
Human
positive regulation of stem cell differentiation GO:2000738 3 0.039
Human Mouse
spermatid differentiation GO:0048515 114 0.039
regulation of protein metabolic process GO:0051246 256 0.039
Mouse Fly
organic hydroxy compound metabolic process GO:1901615 83 0.038
Human
regulation of developmental pigmentation GO:0048070 24 0.038
dna dependent dna replication GO:0006261 17 0.038
cellular amino acid metabolic process GO:0006520 61 0.038
positive regulation of growth GO:0045927 75 0.038
formation of anatomical boundary GO:0048859 37 0.037
regulation of tube length open tracheal system GO:0035159 24 0.037
purine containing compound metabolic process GO:0072521 155 0.036
positive regulation of catalytic activity GO:0043085 118 0.036
neuron fate commitment GO:0048663 50 0.036
negative regulation of cell proliferation GO:0008285 69 0.036
Human Mouse
positive regulation of retinal cell programmed cell death GO:0046670 9 0.036
negative regulation of cell death GO:0060548 81 0.035
Human Mouse
positive regulation of proteolysis GO:0045862 52 0.035
epithelial tube morphogenesis GO:0060562 88 0.035
molting cycle chitin based cuticle GO:0007591 56 0.035
appendage morphogenesis GO:0035107 397 0.035
negative regulation of signaling GO:0023057 219 0.035
Human Mouse
regulation of synapse assembly GO:0051963 94 0.034
regulation of programmed cell death GO:0043067 152 0.034
Human Mouse
negative regulation of dna dependent dna replication GO:2000104 2 0.034
positive regulation of molecular function GO:0044093 136 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.033
canonical wnt signaling pathway GO:0060070 21 0.033
Human
retinal cell programmed cell death GO:0046666 25 0.033
regulation of reproductive process GO:2000241 54 0.033
Mouse
regulation of stem cell proliferation GO:0072091 40 0.032
Mouse
positive regulation of cell development GO:0010720 61 0.032
Human Mouse
epithelial tube formation GO:0072175 7 0.032
kidney epithelium development GO:0072073 3 0.032
regulation of tube size open tracheal system GO:0035151 43 0.032
neuroblast differentiation GO:0014016 29 0.031
regulation of cell development GO:0060284 215 0.031
Human Mouse
growth GO:0040007 359 0.031
negative regulation of nervous system development GO:0051961 92 0.031
cell cell junction organization GO:0045216 55 0.030
Human Mouse Fly
branching morphogenesis of an epithelial tube GO:0048754 45 0.030
terminal branching open tracheal system GO:0007430 17 0.030
cellular protein localization GO:0034613 160 0.029
Human
gland development GO:0048732 191 0.029
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.029
telencephalon development GO:0021537 2 0.029
regulation of dna metabolic process GO:0051052 34 0.028
cell migration involved in gastrulation GO:0042074 9 0.028
Zebrafish
regulation of response to dna damage stimulus GO:2001020 23 0.028
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
nuclear division GO:0000280 332 0.028
ectodermal placode morphogenesis GO:0071697 4 0.028
substrate dependent cell migration GO:0006929 3 0.028
Mouse
heart process GO:0003015 37 0.028
adult locomotory behavior GO:0008344 76 0.027
wing and notum subfield formation GO:0035309 13 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
embryonic hindgut morphogenesis GO:0048619 48 0.027
Fly
morphogenesis of a branching structure GO:0001763 45 0.027
organic hydroxy compound biosynthetic process GO:1901617 21 0.027
Human
meiotic cell cycle GO:0051321 171 0.027
dorsal closure GO:0007391 79 0.027
positive regulation of cell proliferation GO:0008284 47 0.027
protein targeting to nucleus GO:0044744 51 0.026
Human
cytoplasmic transport GO:0016482 130 0.026
Human
positive regulation of cell death GO:0010942 69 0.026
axon extension GO:0048675 32 0.026
wnt signaling pathway GO:0016055 98 0.026
Human
anterior posterior axis specification GO:0009948 109 0.026
histolysis GO:0007559 102 0.026
regulation of protein localization GO:0032880 76 0.025
Human
nucleoside catabolic process GO:0009164 112 0.025
nephron tubule formation GO:0072079 3 0.025
regulation of retinal cell programmed cell death GO:0046668 18 0.025
mitotic nuclear division GO:0007067 213 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
Mouse Fly
response to abiotic stimulus GO:0009628 341 0.025
response to gravity GO:0009629 26 0.025
genital disc sexually dimorphic development GO:0035263 4 0.025
sex differentiation GO:0007548 81 0.024
positive regulation of programmed cell death GO:0043068 62 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
Human
gastrulation with mouth forming first GO:0001703 36 0.023
Fly
negative regulation of notch signaling pathway GO:0045746 41 0.023
positive regulation of immune system process GO:0002684 68 0.022
regulation of embryonic development GO:0045995 68 0.022
Mouse
asymmetric protein localization GO:0008105 33 0.022
vesicle mediated transport GO:0016192 381 0.022
response to radiation GO:0009314 155 0.022
Mouse
negative regulation of neurogenesis GO:0050768 53 0.022
regulation of gene expression epigenetic GO:0040029 128 0.022
positive regulation of developmental process GO:0051094 143 0.022
Human Mouse
nephron development GO:0072006 3 0.022
apoptotic process GO:0006915 159 0.022
Human Mouse
neuromuscular junction development GO:0007528 149 0.022
rhythmic behavior GO:0007622 76 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
malpighian tubule development GO:0072002 64 0.021
Fly
organ growth GO:0035265 56 0.021
camera type eye photoreceptor cell differentiation GO:0060219 2 0.021
histoblast morphogenesis GO:0007488 9 0.021
positive regulation of protein metabolic process GO:0051247 128 0.021
Mouse Fly
purine ribonucleotide metabolic process GO:0009150 145 0.021
nephron epithelium development GO:0072009 3 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
aromatic compound catabolic process GO:0019439 166 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.020
male sex differentiation GO:0046661 25 0.020
regulation of protein import into nucleus GO:0042306 28 0.020
Human
compound eye cone cell differentiation GO:0042675 13 0.020
cranial nerve development GO:0021545 1 0.020
regulation of transferase activity GO:0051338 58 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.020
Human Mouse
ovarian follicle cell development GO:0030707 248 0.020
mitotic cell cycle embryonic GO:0045448 38 0.020
regulation of catalytic activity GO:0050790 185 0.020
single organism intracellular transport GO:1902582 207 0.019
Human
positive regulation of cell differentiation GO:0045597 64 0.019
Human Mouse
epidermal cell differentiation GO:0009913 51 0.019
regulation of apoptotic process GO:0042981 130 0.019
Human Mouse
positive regulation of cell communication GO:0010647 250 0.019
catabolic process GO:0009056 409 0.019
malpighian tubule tip cell differentiation GO:0061382 9 0.019
transmembrane transport GO:0055085 139 0.019
response to organic cyclic compound GO:0014070 89 0.019
Human
hemocyte differentiation GO:0042386 38 0.019
synaptic target recognition GO:0008039 45 0.019
phosphorylation GO:0016310 294 0.019
catechol containing compound biosynthetic process GO:0009713 3 0.019
organ induction GO:0001759 3 0.019
embryonic hemopoiesis GO:0035162 26 0.018
cellular response to ionizing radiation GO:0071479 15 0.018
Mouse
single organism cellular localization GO:1902580 180 0.018
Human
purine nucleoside metabolic process GO:0042278 127 0.018
asymmetric cell division GO:0008356 37 0.018
neuron recognition GO:0008038 101 0.018
torso signaling pathway GO:0008293 21 0.018
macromolecular complex assembly GO:0065003 256 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
Human Mouse
circadian rhythm GO:0007623 105 0.018
cardiovascular system development GO:0072358 82 0.018
Mouse
spiracle morphogenesis open tracheal system GO:0035277 22 0.018
cellular amine metabolic process GO:0044106 12 0.018
regulation of phosphatase activity GO:0010921 3 0.018
regulation of mitotic cell cycle GO:0007346 190 0.017
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.017
regulation of canonical wnt signaling pathway GO:0060828 15 0.017
Human
regulation of cellular protein catabolic process GO:1903362 44 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
neuroblast fate commitment GO:0014017 19 0.017
hematopoietic or lymphoid organ development GO:0048534 57 0.017
dorsal appendage formation GO:0046843 47 0.017
negative regulation of cell development GO:0010721 62 0.017
cardiac cell fate commitment GO:0060911 17 0.017
sex determination GO:0007530 18 0.017
regulation of protein kinase activity GO:0045859 51 0.017
cell adhesion GO:0007155 136 0.016
Human Zebrafish Mouse
negative regulation of cell differentiation GO:0045596 143 0.016
positive regulation of developmental growth GO:0048639 62 0.016
chromatin organization GO:0006325 207 0.016
Mouse Fly
regulation of protein modification process GO:0031399 112 0.016
Mouse Fly
phagocytosis GO:0006909 215 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
dorsal trunk growth open tracheal system GO:0035001 7 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
Human
anatomical structure homeostasis GO:0060249 97 0.016
establishment of localization in cell GO:0051649 402 0.016
Human
anterior posterior pattern specification GO:0009952 136 0.016
negative regulation of intracellular signal transduction GO:1902532 57 0.015
Human
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.015
aromatic amino acid family metabolic process GO:0009072 3 0.015
regulation of compound eye pigmentation GO:0048076 7 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
regulation of protein deacetylation GO:0090311 2 0.015
Fly
embryonic organ development GO:0048568 50 0.015
Mouse
synapse organization GO:0050808 196 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
memory GO:0007613 94 0.014
regulation of steroid metabolic process GO:0019218 2 0.014
Human
retina morphogenesis in camera type eye GO:0060042 2 0.014
positive regulation of wnt signaling pathway GO:0030177 25 0.014
cellular component disassembly GO:0022411 46 0.014
Human Mouse
regulation of nucleocytoplasmic transport GO:0046822 35 0.014
Human
mesoderm formation GO:0001707 21 0.014
Zebrafish Mouse
eye antennal disc development GO:0035214 60 0.014
protein ubiquitination GO:0016567 70 0.014
regulation of tube size GO:0035150 46 0.014
regulation of response to stress GO:0080134 200 0.014
Human
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
muscle cell development GO:0055001 50 0.014
positive regulation of immune response GO:0050778 63 0.014
regulation of hydrolase activity GO:0051336 97 0.013
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.013
regulation of heart morphogenesis GO:2000826 3 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
neuron projection extension GO:1990138 32 0.013
reproductive structure development GO:0048608 74 0.013
Mouse
regulation of establishment of protein localization GO:0070201 61 0.013
Human
negative regulation of cell fate specification GO:0009996 15 0.013
regulation of phosphorylation GO:0042325 147 0.013
circadian behavior GO:0048512 76 0.013
positive regulation of histone deacetylation GO:0031065 2 0.013
Fly
negative regulation of cardioblast differentiation GO:0051892 7 0.013
connective tissue development GO:0061448 3 0.013
Human Mouse
eye antennal disc morphogenesis GO:0007455 34 0.013
eggshell chorion assembly GO:0007306 66 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
cellular macromolecule localization GO:0070727 220 0.013
Human
positive regulation of signal transduction GO:0009967 223 0.013
circadian sleep wake cycle GO:0042745 28 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.013
cellular response to dna damage stimulus GO:0006974 223 0.012
Human
epithelial cell migration GO:0010631 148 0.012
somatic stem cell maintenance GO:0035019 14 0.012
regulation of proteolysis GO:0030162 87 0.012
protein dna complex assembly GO:0065004 63 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
organelle localization GO:0051640 148 0.012
histone modification GO:0016570 106 0.012
Mouse Fly
organ formation GO:0048645 39 0.012
rhythmic process GO:0048511 106 0.012
mitochondrion organization GO:0007005 65 0.012
stem cell development GO:0048864 79 0.012
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
negative regulation of cell cell adhesion GO:0022408 8 0.012
Human Zebrafish
endodermal cell fate commitment GO:0001711 3 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.012
Human Mouse
signal transduction in response to dna damage GO:0042770 3 0.012
Human
endoderm formation GO:0001706 3 0.012
glial cell migration GO:0008347 31 0.012
ras protein signal transduction GO:0007265 88 0.012
nephrocyte diaphragm assembly GO:0036059 3 0.012

esg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040