Drosophila melanogaster

45 known processes

Pde6 (Dmel_CG8279)

Phosphodiesterase 6

(Aliases: PDE6,DmPDE5/6,DmPDE6,CG8279,Dmel\CG8279)

Pde6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 136 0.088
small molecule metabolic process GO:0044281 305 0.049
response to organic substance GO:0010033 284 0.047
organonitrogen compound metabolic process GO:1901564 318 0.042
protein modification process GO:0036211 438 0.042
neurological system process GO:0050877 358 0.041
single organism behavior GO:0044708 391 0.039
vesicle mediated transport GO:0016192 381 0.038
cellular protein modification process GO:0006464 438 0.037
imaginal disc derived wing morphogenesis GO:0007476 337 0.036
single organism biosynthetic process GO:0044711 206 0.036
appendage development GO:0048736 401 0.035
positive regulation of phosphate metabolic process GO:0045937 139 0.035
phosphorylation GO:0016310 294 0.035
regulation of phosphate metabolic process GO:0019220 210 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
positive regulation of biosynthetic process GO:0009891 316 0.034
appendage morphogenesis GO:0035107 397 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
defense response GO:0006952 300 0.034
response to other organism GO:0051707 293 0.033
regulation of multicellular organismal development GO:2000026 414 0.033
cellular response to organic substance GO:0071310 132 0.033
response to abiotic stimulus GO:0009628 341 0.032
cellular catabolic process GO:0044248 372 0.032
Rat
endocytosis GO:0006897 310 0.032
lipid metabolic process GO:0006629 121 0.032
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
post embryonic appendage morphogenesis GO:0035120 385 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
multi organism behavior GO:0051705 175 0.031
organophosphate metabolic process GO:0019637 195 0.030
body morphogenesis GO:0010171 2 0.029
organic substance catabolic process GO:1901575 308 0.029
Rat
cellular response to chemical stimulus GO:0070887 199 0.029
regulation of response to external stimulus GO:0032101 115 0.029
wing disc morphogenesis GO:0007472 344 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
Fly
homeostatic process GO:0042592 199 0.028
negative regulation of response to stimulus GO:0048585 258 0.028
response to external biotic stimulus GO:0043207 293 0.028
response to lipopolysaccharide GO:0032496 4 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
catabolic process GO:0009056 409 0.028
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.028
regulation of localization GO:0032879 275 0.028
cell death GO:0008219 279 0.028
establishment of localization in cell GO:0051649 402 0.028
positive regulation of gene expression GO:0010628 290 0.027
intracellular signal transduction GO:0035556 300 0.027
forebrain development GO:0030900 2 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
organic substance transport GO:0071702 257 0.027
cation transport GO:0006812 110 0.026
organonitrogen compound biosynthetic process GO:1901566 117 0.026
oxoacid metabolic process GO:0043436 103 0.026
mating GO:0007618 120 0.026
immune system process GO:0002376 347 0.026
organic acid metabolic process GO:0006082 103 0.026
multi multicellular organism process GO:0044706 123 0.026
response to monosaccharide GO:0034284 4 0.026
cellular lipid metabolic process GO:0044255 83 0.026
response to biotic stimulus GO:0009607 294 0.026
regionalization GO:0003002 416 0.026
regulation of defense response GO:0031347 102 0.025
death GO:0016265 284 0.025
positive regulation of cell migration GO:0030335 2 0.025
regulation of catalytic activity GO:0050790 185 0.025
male mating behavior GO:0060179 70 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
response to glucose GO:0009749 2 0.025
neuropeptide signaling pathway GO:0007218 45 0.025
courtship behavior GO:0007619 68 0.025
lateral inhibition GO:0046331 206 0.024
Fly
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.024
behavioral response to ethanol GO:0048149 49 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
defense response to other organism GO:0098542 225 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
phagocytosis GO:0006909 215 0.024
positive regulation of cell communication GO:0010647 250 0.023
response to oxygen containing compound GO:1901700 200 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
developmental growth GO:0048589 280 0.023
immune response GO:0006955 246 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
regulation of developmental growth GO:0048638 174 0.022
programmed cell death GO:0012501 257 0.022
single organism catabolic process GO:0044712 228 0.022
Rat
nucleoside phosphate metabolic process GO:0006753 162 0.022
transcription from rna polymerase ii promoter GO:0006366 368 0.022
positive regulation of signal transduction GO:0009967 223 0.022
regulation of response to stress GO:0080134 200 0.022
chaeta development GO:0022416 97 0.022
ion transport GO:0006811 145 0.022
positive regulation of rna metabolic process GO:0051254 271 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
nucleotide metabolic process GO:0009117 161 0.021
regulation of transport GO:0051049 181 0.021
chemotaxis GO:0006935 249 0.021
growth GO:0040007 359 0.021
xenobiotic catabolic process GO:0042178 1 0.021
sensory perception of chemical stimulus GO:0007606 116 0.021
protein localization GO:0008104 284 0.021
response to endogenous stimulus GO:0009719 119 0.021
cellular ketone metabolic process GO:0042180 24 0.021
positive regulation of cell motility GO:2000147 3 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
regulation of cell differentiation GO:0045595 302 0.021
vitamin biosynthetic process GO:0009110 1 0.021
sensory perception GO:0007600 196 0.020
regulation of molecular function GO:0065009 217 0.020
regulation of nervous system development GO:0051960 248 0.020
negative regulation of gene expression GO:0010629 387 0.020
response to organophosphorus GO:0046683 2 0.020
response to organic cyclic compound GO:0014070 89 0.020
steroid catabolic process GO:0006706 1 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
connective tissue development GO:0061448 3 0.020
epithelial cell differentiation GO:0030855 322 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
immune response activating signal transduction GO:0002757 2 0.020
positive regulation of signaling GO:0023056 243 0.020
medium chain fatty acid metabolic process GO:0051791 1 0.020
gland development GO:0048732 191 0.020
hormone catabolic process GO:0042447 3 0.020
central nervous system development GO:0007417 201 0.020
kidney development GO:0001822 3 0.020
endomembrane system organization GO:0010256 119 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.019
purine containing compound metabolic process GO:0072521 155 0.019
developmental programmed cell death GO:0010623 138 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
peptide metabolic process GO:0006518 80 0.019
regulation of growth GO:0040008 233 0.019
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
camera type eye development GO:0043010 4 0.019
response to bacterium GO:0009617 198 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of immune response GO:0050776 118 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
regulation of cell cycle GO:0051726 291 0.018
response to nutrient levels GO:0031667 114 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
camp biosynthetic process GO:0006171 17 0.018
positive regulation of molecular function GO:0044093 136 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
Rat
salivary gland morphogenesis GO:0007435 145 0.018
detection of chemical stimulus GO:0009593 93 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
salivary gland development GO:0007431 162 0.018
single organism intracellular transport GO:1902582 207 0.018
locomotory behavior GO:0007626 176 0.017
organelle assembly GO:0070925 198 0.017
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
regulation of multi organism process GO:0043900 131 0.017
regulation of immune system process GO:0002682 176 0.017
membrane organization GO:0061024 112 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
single organism membrane organization GO:0044802 93 0.017
heterocycle catabolic process GO:0046700 166 0.017
Rat
protein transport GO:0015031 155 0.017
amine metabolic process GO:0009308 12 0.017
male courtship behavior GO:0008049 63 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
negative regulation of developmental process GO:0051093 201 0.017
eye development GO:0001654 323 0.017
regulation of cellular localization GO:0060341 136 0.017
polyol biosynthetic process GO:0046173 3 0.017
cellular homeostasis GO:0019725 80 0.017
peptidyl proline hydroxylation GO:0019511 1 0.017
neurotransmitter metabolic process GO:0042133 2 0.017
negative regulation of signal transduction GO:0009968 206 0.016
proteolysis GO:0006508 192 0.016
organelle fission GO:0048285 340 0.016
gland morphogenesis GO:0022612 145 0.016
l amino acid import GO:0043092 2 0.016
activation of innate immune response GO:0002218 4 0.016
peptidyl amino acid modification GO:0018193 105 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
Rat
chemical homeostasis GO:0048878 92 0.016
cell proliferation GO:0008283 299 0.016
telencephalon development GO:0021537 2 0.016
cellular macromolecule localization GO:0070727 220 0.016
cyclic nucleotide metabolic process GO:0009187 28 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
regulation of catabolic process GO:0009894 170 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.016
mapk cascade GO:0000165 107 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
actin cytoskeleton organization GO:0030036 206 0.016
epithelial cell development GO:0002064 274 0.016
regulation of programmed cell death GO:0043067 152 0.016
aromatic compound catabolic process GO:0019439 166 0.016
Rat
spindle organization GO:0007051 253 0.015
metal ion transport GO:0030001 74 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
localization of cell GO:0051674 257 0.015
autophagic cell death GO:0048102 83 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
regulation of mapk cascade GO:0043408 92 0.015
negative regulation of cell communication GO:0010648 223 0.015
macromolecular complex assembly GO:0065003 256 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
hindbrain development GO:0030902 2 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
cellular protein localization GO:0034613 160 0.015
cellular amine metabolic process GO:0044106 12 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
detection of stimulus involved in sensory perception GO:0050906 92 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
positive regulation of nucleotide metabolic process GO:0045981 55 0.015
exocrine system development GO:0035272 162 0.015
cellular amide metabolic process GO:0043603 80 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
protein phosphorylation GO:0006468 169 0.015
ras protein signal transduction GO:0007265 88 0.015
monocarboxylic acid transport GO:0015718 3 0.015
regulation of organelle organization GO:0033043 196 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
Rat
response to mercury ion GO:0046689 3 0.015
neuromuscular junction development GO:0007528 149 0.014
multi organism reproductive behavior GO:0044705 121 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
Rat
synaptic transmission GO:0007268 288 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
fat soluble vitamin metabolic process GO:0006775 1 0.014
response to hexose GO:0009746 3 0.014
histolysis GO:0007559 102 0.014
apoptotic process GO:0006915 159 0.014
secondary metabolite catabolic process GO:0090487 1 0.014
response to nitrogen compound GO:1901698 90 0.014
circadian behavior GO:0048512 76 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
establishment of protein localization GO:0045184 163 0.014
tissue death GO:0016271 102 0.014
innate immune response GO:0045087 144 0.014
compound eye morphogenesis GO:0001745 249 0.014
anion homeostasis GO:0055081 3 0.014
chromosome organization GO:0051276 360 0.014
camp metabolic process GO:0046058 19 0.014
Rat Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
nuclear division GO:0000280 332 0.014
negative regulation of signaling GO:0023057 219 0.014
response to radiation GO:0009314 155 0.014
head development GO:0060322 135 0.014
developmental maturation GO:0021700 172 0.014
regulation of cell death GO:0010941 173 0.014
positive regulation of catabolic process GO:0009896 105 0.014
response to starvation GO:0042594 97 0.013
macromolecule catabolic process GO:0009057 161 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
regulation of notch signaling pathway GO:0008593 100 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
positive regulation of exocytosis GO:0045921 4 0.013
positive regulation of transport GO:0051050 92 0.013
molting cycle chitin based cuticle GO:0007591 56 0.013
taxis GO:0042330 304 0.013
axon development GO:0061564 297 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.013
metal ion homeostasis GO:0055065 44 0.013
synapse organization GO:0050808 196 0.013
single organism cellular localization GO:1902580 180 0.013
ribose phosphate biosynthetic process GO:0046390 28 0.013
limb development GO:0060173 1 0.013
salivary gland histolysis GO:0035070 88 0.013
regulation of anatomical structure size GO:0090066 163 0.013
organophosphate catabolic process GO:0046434 112 0.013
Rat
cellular ion homeostasis GO:0006873 39 0.013
regulation of phosphorylation GO:0042325 147 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
notch signaling pathway GO:0007219 120 0.013
purine containing compound biosynthetic process GO:0072522 30 0.013
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
axonogenesis GO:0007409 290 0.013
sensory perception of smell GO:0007608 80 0.013
retina development in camera type eye GO:0060041 4 0.013
tube development GO:0035295 244 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
purine containing compound catabolic process GO:0072523 112 0.013
Rat
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
toxin metabolic process GO:0009404 2 0.013
acetylcholine metabolic process GO:0008291 2 0.013
antimicrobial humoral response GO:0019730 99 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
Rat
response to alcohol GO:0097305 95 0.013
vitamin metabolic process GO:0006766 2 0.013
regulation of protein metabolic process GO:0051246 256 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
regulation of cell development GO:0060284 215 0.013
nitrogen compound transport GO:0071705 85 0.013
segmentation GO:0035282 207 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.013
cell division GO:0051301 248 0.013
response to heat GO:0009408 63 0.013
locomotor rhythm GO:0045475 56 0.013
humoral immune response GO:0006959 117 0.013
rna processing GO:0006396 147 0.013
toxin catabolic process GO:0009407 1 0.013
nucleoside catabolic process GO:0009164 112 0.013
intracellular transport GO:0046907 228 0.013
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
defense response to bacterium GO:0042742 178 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
secretion by cell GO:0032940 101 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
immune effector process GO:0002252 98 0.012
response to organonitrogen compound GO:0010243 75 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
ion transmembrane transport GO:0034220 122 0.012
detection of stimulus GO:0051606 156 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
neuron projection guidance GO:0097485 241 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
brain development GO:0007420 120 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
cellular response to ethanol GO:0071361 4 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
nucleoside metabolic process GO:0009116 127 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
rhythmic process GO:0048511 106 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
leg disc development GO:0035218 92 0.012
nephron development GO:0072006 3 0.012
gene silencing GO:0016458 138 0.012
cell cycle phase transition GO:0044770 140 0.012
eye morphogenesis GO:0048592 260 0.012
cell motility GO:0048870 251 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
axis specification GO:0009798 167 0.012
gtp catabolic process GO:0006184 72 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
compound eye development GO:0048749 307 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
adult behavior GO:0030534 137 0.012
cellular metal ion homeostasis GO:0006875 31 0.012
insecticide metabolic process GO:0017143 2 0.012
mitotic nuclear division GO:0007067 213 0.012
regulation of system process GO:0044057 36 0.012
reproductive behavior GO:0019098 122 0.012
carbohydrate metabolic process GO:0005975 82 0.012
regulation of immune effector process GO:0002697 52 0.012
dephosphorylation GO:0016311 51 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
sensory organ morphogenesis GO:0090596 260 0.012
regulation of response to biotic stimulus GO:0002831 63 0.012
cation homeostasis GO:0055080 51 0.012
olfactory behavior GO:0042048 97 0.012
rhythmic behavior GO:0007622 76 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
dendrite development GO:0016358 204 0.011
secretion GO:0046903 109 0.011
dendrite morphogenesis GO:0048813 199 0.011
open tracheal system development GO:0007424 204 0.011
chromatin modification GO:0016568 147 0.011
nephron epithelium development GO:0072009 3 0.011
response to ethanol GO:0045471 59 0.011
regulation of innate immune response GO:0045088 71 0.011
nephron tubule development GO:0072080 3 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
camera type eye morphogenesis GO:0048593 2 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
regulation of cell proliferation GO:0042127 163 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
cuticle development GO:0042335 86 0.011
cell migration GO:0016477 238 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
cellular divalent inorganic cation homeostasis GO:0072503 23 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
synapse assembly GO:0007416 143 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
triglyceride biosynthetic process GO:0019432 2 0.011
transmembrane transport GO:0055085 139 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
regulation of cell projection organization GO:0031344 92 0.011
mating behavior GO:0007617 106 0.011
spindle assembly GO:0051225 80 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
regulation of neurogenesis GO:0050767 158 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
Rat
regulation of cell cycle process GO:0010564 181 0.011
kidney morphogenesis GO:0060993 3 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of immune response GO:0050778 63 0.011
embryonic pattern specification GO:0009880 174 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
protein catabolic process GO:0030163 101 0.011
response to temperature stimulus GO:0009266 106 0.011
photoreceptor cell development GO:0042461 96 0.011
organelle localization GO:0051640 148 0.011
aggressive behavior GO:0002118 63 0.011
spermatogenesis GO:0007283 200 0.011
regulation of hydrolase activity GO:0051336 97 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
leg disc morphogenesis GO:0007478 80 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
tissue morphogenesis GO:0048729 297 0.011
amide biosynthetic process GO:0043604 42 0.011
negative regulation of developmental growth GO:0048640 64 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
Rat
pattern recognition receptor signaling pathway GO:0002221 2 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
tripartite regional subdivision GO:0007351 103 0.011
insecticide catabolic process GO:0046701 1 0.011
peptide biosynthetic process GO:0043043 42 0.011
antimicrobial peptide production GO:0002775 46 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
cognition GO:0050890 141 0.011
cellular cation homeostasis GO:0030003 38 0.011
regulation of synapse assembly GO:0051963 94 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
chemosensory behavior GO:0007635 106 0.011
neuromuscular synaptic transmission GO:0007274 67 0.011
dna metabolic process GO:0006259 227 0.011
digestive tract development GO:0048565 149 0.011
androgen metabolic process GO:0008209 1 0.011
anterior posterior pattern specification GO:0009952 136 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
negative regulation of growth GO:0045926 84 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
positive regulation of defense response GO:0031349 59 0.010
long term memory GO:0007616 62 0.010
positive regulation of developmental process GO:0051094 143 0.010
neutral lipid biosynthetic process GO:0046460 2 0.010
columnar cuboidal epithelial cell development GO:0002066 249 0.010
actin filament based process GO:0030029 220 0.010
spinal cord development GO:0021510 1 0.010
cell cell junction organization GO:0045216 55 0.010
purine ribonucleotide biosynthetic process GO:0009152 28 0.010
chromatin remodeling GO:0006338 72 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
anatomical structure homeostasis GO:0060249 97 0.010
cellular response to hormone stimulus GO:0032870 44 0.010
innate immune response activating signal transduction GO:0002758 2 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
ovarian follicle cell development GO:0030707 248 0.010
acylglycerol biosynthetic process GO:0046463 2 0.010
sensory perception of pain GO:0019233 4 0.010
determination of adult lifespan GO:0008340 137 0.010
gtp metabolic process GO:0046039 72 0.010
embryonic axis specification GO:0000578 107 0.010
tube morphogenesis GO:0035239 191 0.010

Pde6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
cardiovascular system disease DOID:1287 0 0.029
musculoskeletal system disease DOID:17 0 0.024
nervous system disease DOID:863 0 0.022
hypertension DOID:10763 0 0.021
artery disease DOID:0050828 0 0.021
vascular disease DOID:178 0 0.021
disease of metabolism DOID:0014667 0 0.019
essential hypertension DOID:10825 0 0.018
inherited metabolic disorder DOID:655 0 0.017
central nervous system disease DOID:331 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.011
organ system cancer DOID:0050686 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.010
acquired metabolic disease DOID:0060158 0 0.010