Drosophila melanogaster

30 known processes

agt (Dmel_CG1303)

O-6-alkylguanine-DNA alkyltransferase

(Aliases: BG:DS00004.10,Agt,Dmel\CG1303,DmAGT,CG1303)

agt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.060
small molecule metabolic process GO:0044281 305 0.054
neurological system process GO:0050877 358 0.051
cellular catabolic process GO:0044248 372 0.049
catabolic process GO:0009056 409 0.046
response to abiotic stimulus GO:0009628 341 0.039
organic substance catabolic process GO:1901575 308 0.038
response to biotic stimulus GO:0009607 294 0.037
sensory perception GO:0007600 196 0.037
defense response GO:0006952 300 0.036
carboxylic acid metabolic process GO:0019752 92 0.033
organic cyclic compound catabolic process GO:1901361 168 0.033
establishment of localization in cell GO:0051649 402 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
steroid catabolic process GO:0006706 1 0.032
immune response GO:0006955 246 0.031
response to external biotic stimulus GO:0043207 293 0.031
response to other organism GO:0051707 293 0.031
vesicle mediated transport GO:0016192 381 0.030
negative regulation of response to stimulus GO:0048585 258 0.029
regulation of cell differentiation GO:0045595 302 0.029
single organism catabolic process GO:0044712 228 0.029
immune system process GO:0002376 347 0.029
positive regulation of signaling GO:0023056 243 0.028
endocytosis GO:0006897 310 0.028
defense response to other organism GO:0098542 225 0.028
defense response to bacterium GO:0042742 178 0.028
oxoacid metabolic process GO:0043436 103 0.028
xenobiotic catabolic process GO:0042178 1 0.027
amine metabolic process GO:0009308 12 0.027
response to bacterium GO:0009617 198 0.027
response to lipopolysaccharide GO:0032496 4 0.026
central nervous system development GO:0007417 201 0.026
response to organic substance GO:0010033 284 0.025
nucleotide metabolic process GO:0009117 161 0.025
organic acid metabolic process GO:0006082 103 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
positive regulation of cell communication GO:0010647 250 0.024
homeostatic process GO:0042592 199 0.024
forebrain development GO:0030900 2 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
response to organophosphorus GO:0046683 2 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
intracellular transport GO:0046907 228 0.024
cellular ketone metabolic process GO:0042180 24 0.023
innate immune response GO:0045087 144 0.023
aromatic compound catabolic process GO:0019439 166 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
phosphorylation GO:0016310 294 0.023
single organism behavior GO:0044708 391 0.023
compound eye development GO:0048749 307 0.022
organophosphate metabolic process GO:0019637 195 0.022
appendage development GO:0048736 401 0.022
sensory perception of chemical stimulus GO:0007606 116 0.022
phagocytosis GO:0006909 215 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
regulation of catalytic activity GO:0050790 185 0.021
purine ribonucleoside metabolic process GO:0046128 127 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
defense response to gram negative bacterium GO:0050829 94 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
brain development GO:0007420 120 0.020
regulation of immune response GO:0050776 118 0.020
positive regulation of signal transduction GO:0009967 223 0.020
heterocycle catabolic process GO:0046700 166 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
axon guidance GO:0007411 233 0.020
organic substance transport GO:0071702 257 0.020
chromosome organization GO:0051276 360 0.020
negative regulation of gene expression GO:0010629 387 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
regulation of immune system process GO:0002682 176 0.020
regulation of cell cycle GO:0051726 291 0.020
head development GO:0060322 135 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
protein modification process GO:0036211 438 0.019
anatomical structure homeostasis GO:0060249 97 0.019
single organism intracellular transport GO:1902582 207 0.019
body morphogenesis GO:0010171 2 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
neuron projection guidance GO:0097485 241 0.019
programmed cell death GO:0012501 257 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
regulation of response to stress GO:0080134 200 0.019
response to oxygen containing compound GO:1901700 200 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
regulation of cell development GO:0060284 215 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
organelle fission GO:0048285 340 0.019
sensory perception of smell GO:0007608 80 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
purine containing compound metabolic process GO:0072521 155 0.018
chaeta development GO:0022416 97 0.018
rna processing GO:0006396 147 0.018
macromolecular complex assembly GO:0065003 256 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
single organism biosynthetic process GO:0044711 206 0.018
cellular protein modification process GO:0006464 438 0.018
regulation of nervous system development GO:0051960 248 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
appendage morphogenesis GO:0035107 397 0.018
mrna metabolic process GO:0016071 124 0.018
regulation of defense response GO:0031347 102 0.018
transmembrane transport GO:0055085 139 0.018
intracellular signal transduction GO:0035556 300 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
wing disc morphogenesis GO:0007472 344 0.017
death GO:0016265 284 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
response to monosaccharide GO:0034284 4 0.017
response to hexose GO:0009746 3 0.017
response to mercury ion GO:0046689 3 0.017
telencephalon development GO:0021537 2 0.017
regulation of molecular function GO:0065009 217 0.017
nuclear division GO:0000280 332 0.017
eye morphogenesis GO:0048592 260 0.017
regulation of localization GO:0032879 275 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
protein localization GO:0008104 284 0.016
regulation of protein metabolic process GO:0051246 256 0.016
cytoplasmic transport GO:0016482 130 0.016
mrna processing GO:0006397 104 0.016
cell division GO:0051301 248 0.016
response to nutrient levels GO:0031667 114 0.016
eye development GO:0001654 323 0.016
vitamin metabolic process GO:0006766 2 0.016
peptide metabolic process GO:0006518 80 0.016
response to extracellular stimulus GO:0009991 116 0.016
taxis GO:0042330 304 0.016
nucleoside metabolic process GO:0009116 127 0.016
locomotory behavior GO:0007626 176 0.016
gland development GO:0048732 191 0.016
immune response activating signal transduction GO:0002757 2 0.016
positive regulation of catalytic activity GO:0043085 118 0.015
growth GO:0040007 359 0.015
lipid metabolic process GO:0006629 121 0.015
macromolecule catabolic process GO:0009057 161 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
nucleoside catabolic process GO:0009164 112 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
organophosphate catabolic process GO:0046434 112 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
camera type eye development GO:0043010 4 0.015
regulation of cell death GO:0010941 173 0.015
dendrite development GO:0016358 204 0.015
response to endogenous stimulus GO:0009719 119 0.015
developmental growth GO:0048589 280 0.015
anion homeostasis GO:0055081 3 0.015
cellular amine metabolic process GO:0044106 12 0.015
positive regulation of molecular function GO:0044093 136 0.015
compound eye morphogenesis GO:0001745 249 0.014
toxin catabolic process GO:0009407 1 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
purine containing compound catabolic process GO:0072523 112 0.014
regulation of innate immune response GO:0045088 71 0.014
chemotaxis GO:0006935 249 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
regulation of programmed cell death GO:0043067 152 0.014
response to radiation GO:0009314 155 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
cell death GO:0008219 279 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
regulation of cell cycle process GO:0010564 181 0.014
male gamete generation GO:0048232 201 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
positive regulation of cell motility GO:2000147 3 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
vitamin biosynthetic process GO:0009110 1 0.014
regionalization GO:0003002 416 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
small gtpase mediated signal transduction GO:0007264 88 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
response to glucose GO:0009749 2 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
detection of chemical stimulus GO:0009593 93 0.013
rna splicing via transesterification reactions GO:0000375 73 0.013
regulation of transport GO:0051049 181 0.013
regulation of neurogenesis GO:0050767 158 0.013
hormone catabolic process GO:0042447 3 0.013
negative regulation of developmental process GO:0051093 201 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
positive regulation of cell migration GO:0030335 2 0.013
nitrogen compound transport GO:0071705 85 0.013
segmentation GO:0035282 207 0.013
single organism cellular localization GO:1902580 180 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
androgen metabolic process GO:0008209 1 0.013
negative regulation of signaling GO:0023057 219 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
glutathione metabolic process GO:0006749 37 0.012
adult behavior GO:0030534 137 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
cell adhesion GO:0007155 136 0.012
apoptotic process GO:0006915 159 0.012
spindle organization GO:0007051 253 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
dna metabolic process GO:0006259 227 0.012
open tracheal system development GO:0007424 204 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
axon development GO:0061564 297 0.012
protein complex assembly GO:0006461 200 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
detection of stimulus GO:0051606 156 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
ras protein signal transduction GO:0007265 88 0.012
negative regulation of signal transduction GO:0009968 206 0.012
cellular amide metabolic process GO:0043603 80 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of anatomical structure size GO:0090066 163 0.012
nuclear transport GO:0051169 72 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
toxin metabolic process GO:0009404 2 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
nucleotide catabolic process GO:0009166 109 0.012
epithelial cell development GO:0002064 274 0.012
meiotic cell cycle process GO:1903046 132 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
cellular macromolecule localization GO:0070727 220 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
cellular homeostasis GO:0019725 80 0.012
biological adhesion GO:0022610 138 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
protein phosphorylation GO:0006468 169 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
epithelial cell differentiation GO:0030855 322 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
axonogenesis GO:0007409 290 0.012
rna splicing GO:0008380 83 0.012
lateral inhibition GO:0046331 206 0.011
cellular protein localization GO:0034613 160 0.011
dendrite morphogenesis GO:0048813 199 0.011
response to starvation GO:0042594 97 0.011
protein complex biogenesis GO:0070271 201 0.011
cellular response to organic substance GO:0071310 132 0.011
regulation of cellular localization GO:0060341 136 0.011
response to copper ion GO:0046688 4 0.011
secretion GO:0046903 109 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
developmental programmed cell death GO:0010623 138 0.011
regulation of mrna processing GO:0050684 71 0.011
ion transport GO:0006811 145 0.011
cellular lipid metabolic process GO:0044255 83 0.011
salivary gland development GO:0007431 162 0.011
establishment of protein localization GO:0045184 163 0.011
regulation of phosphorylation GO:0042325 147 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
cellular response to ethanol GO:0071361 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
salivary gland morphogenesis GO:0007435 145 0.011
protein transport GO:0015031 155 0.011
proteolysis GO:0006508 192 0.011
polyol biosynthetic process GO:0046173 3 0.011
negative regulation of cell communication GO:0010648 223 0.011
response to nitrogen compound GO:1901698 90 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
regulation of rna splicing GO:0043484 69 0.011
regulation of growth GO:0040008 233 0.011
embryonic pattern specification GO:0009880 174 0.011
somatic muscle development GO:0007525 66 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
chemical homeostasis GO:0048878 92 0.011
multi organism behavior GO:0051705 175 0.011
positive regulation of gene expression GO:0010628 290 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
cell cycle phase transition GO:0044770 140 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
respiratory system development GO:0060541 213 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
negative regulation of homeostatic process GO:0032845 2 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
response to organonitrogen compound GO:0010243 75 0.010
cation transport GO:0006812 110 0.010
activation of innate immune response GO:0002218 4 0.010
rna localization GO:0006403 115 0.010
kidney development GO:0001822 3 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
carbohydrate metabolic process GO:0005975 82 0.010
mitotic nuclear division GO:0007067 213 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010

agt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.017
cardiovascular system disease DOID:1287 0 0.016
artery disease DOID:0050828 0 0.015
vascular disease DOID:178 0 0.015
hypertension DOID:10763 0 0.014
essential hypertension DOID:10825 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014