Drosophila melanogaster

141 known processes

cdc23 (Dmel_CG2508)

CG2508 gene product from transcript CG2508-RA

(Aliases: CG2508-PA,CG2508,Cdc23,38C.54,Apc8,Dmel\CG2508)

cdc23 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.630
modification dependent macromolecule catabolic process GO:0043632 79 0.320
ubiquitin dependent protein catabolic process GO:0006511 78 0.317
sister chromatid segregation GO:0000819 92 0.279
organelle fission GO:0048285 340 0.262
dna metabolic process GO:0006259 227 0.246
regulation of chromosome organization GO:0033044 64 0.214
mitotic sister chromatid separation GO:0051306 30 0.200
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.200
ovarian follicle cell development GO:0030707 248 0.197
gene silencing GO:0016458 138 0.193
eggshell formation GO:0030703 105 0.182
regulation of organelle organization GO:0033043 196 0.168
cellular protein modification process GO:0006464 438 0.166
protein ubiquitination GO:0016567 70 0.154
regulation of cell cycle phase transition GO:1901987 130 0.146
positive regulation of macromolecule metabolic process GO:0010604 405 0.146
imaginal disc derived appendage development GO:0048737 399 0.136
protein modification process GO:0036211 438 0.134
axonogenesis GO:0007409 290 0.128
mitotic nuclear division GO:0007067 213 0.126
appendage development GO:0048736 401 0.119
regulation of cell cycle process GO:0010564 181 0.116
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.116
cell cycle phase transition GO:0044770 140 0.116
chromosome separation GO:0051304 42 0.114
negative regulation of cellular biosynthetic process GO:0031327 277 0.109
mitotic cytokinesis GO:0000281 50 0.108
modification dependent protein catabolic process GO:0019941 78 0.107
cellular protein catabolic process GO:0044257 83 0.106
cellular macromolecule catabolic process GO:0044265 136 0.102
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.100
appendage morphogenesis GO:0035107 397 0.098
negative regulation of biosynthetic process GO:0009890 277 0.096
meiotic cell cycle GO:0051321 171 0.094
meiotic nuclear division GO:0007126 151 0.090
transcription from rna polymerase ii promoter GO:0006366 368 0.088
protein modification by small protein conjugation or removal GO:0070647 106 0.088
post embryonic appendage morphogenesis GO:0035120 385 0.088
mitotic spindle organization GO:0007052 220 0.087
telomere organization GO:0032200 21 0.086
regulation of cell division GO:0051302 72 0.086
protein modification by small protein conjugation GO:0032446 79 0.085
chromosome segregation GO:0007059 157 0.084
mitotic spindle elongation GO:0000022 81 0.083
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.081
spermatogenesis GO:0007283 200 0.081
positive regulation of cellular component organization GO:0051130 156 0.080
organonitrogen compound metabolic process GO:1901564 318 0.078
mitotic sister chromatid segregation GO:0000070 87 0.078
nuclear division GO:0000280 332 0.077
negative regulation of gene expression GO:0010629 387 0.076
regulation of mitosis GO:0007088 56 0.074
response to organic substance GO:0010033 284 0.073
catabolic process GO:0009056 409 0.070
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.067
wing disc morphogenesis GO:0007472 344 0.066
negative regulation of cellular metabolic process GO:0031324 382 0.064
regulation of mitotic sister chromatid separation GO:0010965 28 0.059
axon development GO:0061564 297 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.057
imaginal disc derived appendage morphogenesis GO:0035114 395 0.056
regulation of cellular protein metabolic process GO:0032268 243 0.055
macromolecule catabolic process GO:0009057 161 0.054
proteolysis GO:0006508 192 0.054
protein localization GO:0008104 284 0.053
organelle assembly GO:0070925 198 0.053
chromatin organization GO:0006325 207 0.053
regulation of cell cycle GO:0051726 291 0.053
homeostatic process GO:0042592 199 0.051
small molecule metabolic process GO:0044281 305 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.051
regulation of sister chromatid segregation GO:0033045 28 0.050
single organism catabolic process GO:0044712 228 0.049
regulation of protein catabolic process GO:0042176 55 0.047
macromolecular complex assembly GO:0065003 256 0.047
regulation of mitotic cell cycle phase transition GO:1901990 130 0.043
endocytosis GO:0006897 310 0.043
regulation of dna metabolic process GO:0051052 34 0.042
cellularization GO:0007349 90 0.041
positive regulation of nucleic acid templated transcription GO:1903508 266 0.041
regulation of proteasomal protein catabolic process GO:0061136 39 0.041
positive regulation of cellular biosynthetic process GO:0031328 316 0.041
reproductive system development GO:0061458 74 0.041
cell cycle checkpoint GO:0000075 95 0.041
cellular protein complex assembly GO:0043623 71 0.041
phosphorylation GO:0016310 294 0.040
negative regulation of cell cycle phase transition GO:1901988 103 0.040
positive regulation of protein catabolic process GO:0045732 34 0.040
cellular response to dna damage stimulus GO:0006974 223 0.040
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.039
histone modification GO:0016570 106 0.039
negative regulation of nucleic acid templated transcription GO:1903507 240 0.039
spindle organization GO:0007051 253 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
regulation of protein metabolic process GO:0051246 256 0.038
dna damage checkpoint GO:0000077 78 0.038
microtubule depolymerization GO:0007019 25 0.037
ameboidal type cell migration GO:0001667 151 0.037
dna packaging GO:0006323 91 0.036
meiotic cell cycle process GO:1903046 132 0.036
ncrna metabolic process GO:0034660 43 0.036
defense response GO:0006952 300 0.036
metaphase anaphase transition of cell cycle GO:0044784 28 0.036
cellular macromolecular complex assembly GO:0034622 153 0.035
macromolecular complex disassembly GO:0032984 37 0.035
protein complex assembly GO:0006461 200 0.035
regulation of protein complex disassembly GO:0043244 29 0.035
spindle midzone assembly GO:0051255 4 0.035
regulation of proteolysis GO:0030162 87 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.034
regulation of cellular protein catabolic process GO:1903362 44 0.033
regulation of mitotic cell cycle GO:0007346 190 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
eye development GO:0001654 323 0.031
cellular response to abiotic stimulus GO:0071214 58 0.031
mitotic metaphase plate congression GO:0007080 13 0.031
spindle assembly GO:0051225 80 0.031
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.031
protein complex biogenesis GO:0070271 201 0.031
sex differentiation GO:0007548 81 0.030
establishment of organelle localization GO:0051656 122 0.030
protein phosphorylation GO:0006468 169 0.029
oxoacid metabolic process GO:0043436 103 0.029
single fertilization GO:0007338 24 0.029
reproductive structure development GO:0048608 74 0.029
positive regulation of gene expression GO:0010628 290 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
humoral immune response GO:0006959 117 0.028
gland development GO:0048732 191 0.028
regulation of nuclear division GO:0051783 58 0.028
axon guidance GO:0007411 233 0.028
negative regulation of transcription dna templated GO:0045892 237 0.028
multi organism behavior GO:0051705 175 0.027
meiotic chromosome segregation GO:0045132 59 0.027
dendrite development GO:0016358 204 0.027
columnar cuboidal epithelial cell development GO:0002066 249 0.027
transmembrane transport GO:0055085 139 0.027
negative regulation of dna dependent dna replication GO:2000104 2 0.027
positive regulation of proteolysis GO:0045862 52 0.027
regionalization GO:0003002 416 0.027
metaphase plate congression GO:0051310 19 0.027
morphogenesis of an epithelium GO:0002009 276 0.027
Fly
protein catabolic process GO:0030163 101 0.027
regulation of response to stress GO:0080134 200 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
dna replication GO:0006260 48 0.026
organic substance catabolic process GO:1901575 308 0.026
organic acid metabolic process GO:0006082 103 0.026
pole cell development GO:0007277 26 0.025
cytokinesis GO:0000910 90 0.025
epithelial cell development GO:0002064 274 0.025
regulation of phosphate metabolic process GO:0019220 210 0.025
positive regulation of cellular catabolic process GO:0031331 95 0.025
protein localization to organelle GO:0033365 82 0.025
organelle localization GO:0051640 148 0.025
negative regulation of cell death GO:0060548 81 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.025
chromatin modification GO:0016568 147 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.024
positive regulation of catabolic process GO:0009896 105 0.024
programmed cell death GO:0012501 257 0.024
regulation of multi organism process GO:0043900 131 0.024
regulation of protein modification process GO:0031399 112 0.023
tube morphogenesis GO:0035239 191 0.023
regulation of neurogenesis GO:0050767 158 0.023
establishment of chromosome localization GO:0051303 20 0.023
regulation of mitotic sister chromatid segregation GO:0033047 28 0.023
response to abiotic stimulus GO:0009628 341 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.022
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.022
dendrite morphogenesis GO:0048813 199 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
regulation of molecular function GO:0065009 217 0.022
cell division GO:0051301 248 0.022
response to oxygen containing compound GO:1901700 200 0.022
regulation of meiosis GO:0040020 3 0.022
immune system process GO:0002376 347 0.021
open tracheal system development GO:0007424 204 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.021
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.021
negative regulation of protein depolymerization GO:1901880 23 0.021
epithelial cell differentiation GO:0030855 322 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
cellular ketone metabolic process GO:0042180 24 0.021
organic substance transport GO:0071702 257 0.020
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.020
regulation of catalytic activity GO:0050790 185 0.020
negative regulation of mitotic cell cycle GO:0045930 109 0.020
compound eye morphogenesis GO:0001745 249 0.020
regulation of cellular catabolic process GO:0031329 157 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
regulation of protein depolymerization GO:1901879 27 0.020
regulation of gene silencing GO:0060968 63 0.020
axis specification GO:0009798 167 0.020
g2 dna damage checkpoint GO:0031572 69 0.020
mitotic chromosome condensation GO:0007076 22 0.020
cell death GO:0008219 279 0.019
regulation of microtubule depolymerization GO:0031114 24 0.019
localization of cell GO:0051674 257 0.019
response to other organism GO:0051707 293 0.019
tissue morphogenesis GO:0048729 297 0.019
Fly
regulation of chromosome segregation GO:0051983 32 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
organophosphate metabolic process GO:0019637 195 0.019
negative regulation of cell cycle process GO:0010948 109 0.019
regulation of cell differentiation GO:0045595 302 0.019
mrna processing GO:0006397 104 0.019
wound healing GO:0042060 75 0.019
positive regulation of cell cycle process GO:0090068 28 0.019
positive regulation of transcription dna templated GO:0045893 266 0.018
positive regulation of cellular protein catabolic process GO:1903364 24 0.018
establishment of localization in cell GO:0051649 402 0.018
intracellular signal transduction GO:0035556 300 0.018
positive regulation of mitotic cell cycle GO:0045931 34 0.018
ras protein signal transduction GO:0007265 88 0.018
centrosome cycle GO:0007098 137 0.018
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.018
sensory organ morphogenesis GO:0090596 260 0.018
rna processing GO:0006396 147 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.018
regulation of localization GO:0032879 275 0.018
cellular protein complex disassembly GO:0043624 35 0.017
female meiotic division GO:0007143 70 0.017
double strand break repair GO:0006302 26 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
spindle assembly involved in mitosis GO:0090307 50 0.017
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.017
cellular catabolic process GO:0044248 372 0.017
covalent chromatin modification GO:0016569 106 0.017
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.017
dna conformation change GO:0071103 105 0.017
negative regulation of microtubule depolymerization GO:0007026 21 0.017
regulation of microtubule cytoskeleton organization GO:0070507 41 0.017
peptidyl amino acid modification GO:0018193 105 0.017
developmental programmed cell death GO:0010623 138 0.017
cellular response to organic substance GO:0071310 132 0.017
regulation of catabolic process GO:0009894 170 0.016
cell fate determination GO:0001709 91 0.016
negative regulation of cell communication GO:0010648 223 0.016
positive regulation of cell cycle GO:0045787 43 0.016
anatomical structure homeostasis GO:0060249 97 0.016
gene silencing by rna GO:0031047 57 0.016
non sensory hair organization GO:0035316 47 0.016
nuclear body organization GO:0030575 6 0.016
development of primary sexual characteristics GO:0045137 50 0.016
mitotic cell cycle checkpoint GO:0007093 88 0.016
nucleotide catabolic process GO:0009166 109 0.016
positive regulation of cell division GO:0051781 16 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
response to radiation GO:0009314 155 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
nucleus organization GO:0006997 45 0.015
cellular macromolecule localization GO:0070727 220 0.015
sensory perception GO:0007600 196 0.015
positive regulation of molecular function GO:0044093 136 0.015
multi organism reproductive behavior GO:0044705 121 0.015
spermatid development GO:0007286 98 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
negative regulation of developmental process GO:0051093 201 0.015
ion transport GO:0006811 145 0.015
taxis GO:0042330 304 0.015
regulation of multicellular organismal development GO:2000026 414 0.014
Fly
protein depolymerization GO:0051261 31 0.014
segmentation GO:0035282 207 0.014
defense response to bacterium GO:0042742 178 0.014
neuron projection guidance GO:0097485 241 0.014
regulation of cellular response to stress GO:0080135 89 0.014
metal ion transport GO:0030001 74 0.014
chemotaxis GO:0006935 249 0.014
protein dna complex subunit organization GO:0071824 86 0.014
kinetochore organization GO:0051383 9 0.014
body morphogenesis GO:0010171 2 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
histolysis GO:0007559 102 0.013
heart process GO:0003015 37 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
positive regulation of transport GO:0051050 92 0.013
positive regulation of signaling GO:0023056 243 0.013
pole cell formation GO:0007279 19 0.013
negative regulation of protein complex disassembly GO:0043242 23 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
apoptotic process GO:0006915 159 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
regulation of spindle organization GO:0090224 17 0.013
negative regulation of signal transduction GO:0009968 206 0.013
regulation of immune response GO:0050776 118 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
actin cytoskeleton organization GO:0030036 206 0.013
microtubule organizing center organization GO:0031023 168 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
anterior posterior axis specification GO:0009948 109 0.013
regulation of chromatin organization GO:1902275 32 0.013
nicotinamide nucleotide metabolic process GO:0046496 2 0.013
positive regulation of chromosome segregation GO:0051984 10 0.013
wnt signaling pathway GO:0016055 98 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
tissue death GO:0016271 102 0.012
regulation of transport GO:0051049 181 0.012
actin mediated cell contraction GO:0070252 21 0.012
cellular protein localization GO:0034613 160 0.012
salivary gland histolysis GO:0035070 88 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
actin filament based process GO:0030029 220 0.012
wing disc pattern formation GO:0035222 66 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
response to light stimulus GO:0009416 124 0.012
developmental maturation GO:0021700 172 0.012
embryonic pattern specification GO:0009880 174 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
male meiosis GO:0007140 52 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
dna biosynthetic process GO:0071897 24 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
telomere maintenance GO:0000723 21 0.012
growth GO:0040007 359 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
response to external biotic stimulus GO:0043207 293 0.012
regulation of defense response GO:0031347 102 0.012
mrna metabolic process GO:0016071 124 0.012
regulation of cell proliferation GO:0042127 163 0.012
synaptic transmission GO:0007268 288 0.012
cell proliferation GO:0008283 299 0.012
phagocytosis GO:0006909 215 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
response to biotic stimulus GO:0009607 294 0.011
negative regulation of cytoskeleton organization GO:0051494 30 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
cation transport GO:0006812 110 0.011
exocrine system development GO:0035272 162 0.011
mitotic spindle midzone assembly GO:0051256 1 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
digestive tract development GO:0048565 149 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
cell maturation GO:0048469 144 0.011
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.011
protein complex disassembly GO:0043241 36 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
regulation of immune system process GO:0002682 176 0.011
rna localization GO:0006403 115 0.011
maintenance of location GO:0051235 73 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
compound eye development GO:0048749 307 0.011
single organism cellular localization GO:1902580 180 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
cellular homeostasis GO:0019725 80 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
karyosome formation GO:0030717 22 0.010
establishment of planar polarity GO:0001736 87 0.010
Fly
regulation of nervous system development GO:0051960 248 0.010
protein processing GO:0016485 68 0.010
secretion by cell GO:0032940 101 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
male pronucleus assembly GO:0035039 6 0.010
response to nitrogen compound GO:1901698 90 0.010
cellular response to radiation GO:0071478 52 0.010
positive regulation of multi organism process GO:0043902 40 0.010
salivary gland development GO:0007431 162 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010

cdc23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.011