Drosophila melanogaster

2 known processes

alpha-Est2 (Dmel_CG2505)

alpha-Esterase-2

(Aliases: aE2,Alpha-Est2,CG2505,DmalphaE2,alphaE2,B,Dmel\CG2505,alpha-EST2)

alpha-Est2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mating GO:0007618 120 0.292
Fly
female mating behavior GO:0060180 30 0.123
reproductive behavior GO:0019098 122 0.122
Fly
multi organism reproductive behavior GO:0044705 121 0.114
Fly
multi organism behavior GO:0051705 175 0.111
Fly
response to biotic stimulus GO:0009607 294 0.097
Fly
compound eye development GO:0048749 307 0.091
response to organophosphorus GO:0046683 2 0.088
Fly
response to external biotic stimulus GO:0043207 293 0.087
Fly
response to bacterium GO:0009617 198 0.086
compound eye morphogenesis GO:0001745 249 0.084
eye development GO:0001654 323 0.079
steroid catabolic process GO:0006706 1 0.078
proteolysis GO:0006508 192 0.075
small molecule metabolic process GO:0044281 305 0.072
Fly
mating behavior GO:0007617 106 0.072
Fly
defense response to other organism GO:0098542 225 0.068
Fly
eye morphogenesis GO:0048592 260 0.068
sensory organ morphogenesis GO:0090596 260 0.068
single organism catabolic process GO:0044712 228 0.067
Fly
multi multicellular organism process GO:0044706 123 0.065
Fly
negative regulation of female receptivity GO:0007621 14 0.063
secondary metabolic process GO:0019748 75 0.061
catabolic process GO:0009056 409 0.059
Fly
defense response GO:0006952 300 0.059
Fly
organonitrogen compound metabolic process GO:1901564 318 0.058
Fly
anion homeostasis GO:0055081 3 0.058
cellular catabolic process GO:0044248 372 0.055
Fly
organic substance catabolic process GO:1901575 308 0.054
Fly
response to other organism GO:0051707 293 0.054
Fly
multicellular organismal reproductive behavior GO:0033057 110 0.053
Fly
xenobiotic catabolic process GO:0042178 1 0.050
organic acid metabolic process GO:0006082 103 0.050
organonitrogen compound catabolic process GO:1901565 128 0.050
Fly
single organism biosynthetic process GO:0044711 206 0.049
oxoacid metabolic process GO:0043436 103 0.046
carboxylic acid metabolic process GO:0019752 92 0.046
lipid metabolic process GO:0006629 121 0.045
androgen metabolic process GO:0008209 1 0.045
response to organic substance GO:0010033 284 0.044
Fly
cell recognition GO:0008037 102 0.043
Fly
fat soluble vitamin metabolic process GO:0006775 1 0.043
neurological system process GO:0050877 358 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.042
Fly
vitamin metabolic process GO:0006766 2 0.041
pigment metabolic process GO:0042440 84 0.040
response to abiotic stimulus GO:0009628 341 0.040
Fly
positive regulation of lipid storage GO:0010884 4 0.039
imaginal disc derived appendage development GO:0048737 399 0.038
Fly
medium chain fatty acid metabolic process GO:0051791 1 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.037
Fly
secondary metabolite catabolic process GO:0090487 1 0.037
organic hydroxy compound metabolic process GO:1901615 83 0.036
Fly
appendage development GO:0048736 401 0.036
Fly
detection of chemical stimulus GO:0009593 93 0.036
regulation of female receptivity GO:0045924 24 0.035
polyol biosynthetic process GO:0046173 3 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
Fly
cellular amino acid metabolic process GO:0006520 61 0.034
vitamin biosynthetic process GO:0009110 1 0.034
kidney development GO:0001822 3 0.034
gland development GO:0048732 191 0.034
detection of stimulus GO:0051606 156 0.033
appendage morphogenesis GO:0035107 397 0.033
Fly
cellular response to lipopolysaccharide GO:0071222 3 0.033
single organism behavior GO:0044708 391 0.032
cell death GO:0008219 279 0.032
regulation of localization GO:0032879 275 0.031
taxis GO:0042330 304 0.031
Fly
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.031
ethanolamine containing compound metabolic process GO:0042439 4 0.031
Fly
cellular ketone metabolic process GO:0042180 24 0.030
immune response GO:0006955 246 0.030
vesicle mediated transport GO:0016192 381 0.030
insecticide metabolic process GO:0017143 2 0.030
lauric acid metabolic process GO:0048252 1 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
wing disc morphogenesis GO:0007472 344 0.030
Fly
organic cyclic compound catabolic process GO:1901361 168 0.030
defense response to bacterium GO:0042742 178 0.029
tissue death GO:0016271 102 0.029
organic substance transport GO:0071702 257 0.029
death GO:0016265 284 0.029
chemotaxis GO:0006935 249 0.029
Fly
regulation of female receptivity post mating GO:0046008 17 0.029
response to temperature stimulus GO:0009266 106 0.028
cholesterol transport GO:0030301 2 0.028
programmed cell death GO:0012501 257 0.027
neuron projection guidance GO:0097485 241 0.027
Fly
establishment of localization in cell GO:0051649 402 0.027
response to nutrient levels GO:0031667 114 0.027
salivary gland development GO:0007431 162 0.027
developmental programmed cell death GO:0010623 138 0.027
insecticide catabolic process GO:0046701 1 0.027
response to lipopolysaccharide GO:0032496 4 0.026
salivary gland morphogenesis GO:0007435 145 0.026
sensory perception of smell GO:0007608 80 0.026
innate immune response GO:0045087 144 0.026
endocytosis GO:0006897 310 0.026
immune system process GO:0002376 347 0.025
steroid metabolic process GO:0008202 20 0.025
axon development GO:0061564 297 0.025
Fly
phagocytosis GO:0006909 215 0.025
toxin catabolic process GO:0009407 1 0.025
toxin metabolic process GO:0009404 2 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
regulation of lipid storage GO:0010883 22 0.025
fat soluble vitamin biosynthetic process GO:0042362 1 0.025
regionalization GO:0003002 416 0.025
Fly
salivary gland cell autophagic cell death GO:0035071 83 0.025
sensory perception of chemical stimulus GO:0007606 116 0.024
histolysis GO:0007559 102 0.024
response to oxygen containing compound GO:1901700 200 0.024
sensory perception GO:0007600 196 0.024
response to extracellular stimulus GO:0009991 116 0.024
steroid biosynthetic process GO:0006694 16 0.024
hormone catabolic process GO:0042447 3 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
developmental growth GO:0048589 280 0.024
cellular lipid metabolic process GO:0044255 83 0.023
exocrine system development GO:0035272 162 0.023
hormone metabolic process GO:0042445 33 0.023
acetylcholine catabolic process GO:0006581 1 0.023
Fly
organelle fission GO:0048285 340 0.023
Fly
regulation of anatomical structure size GO:0090066 163 0.023
Fly
protein modification process GO:0036211 438 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
body morphogenesis GO:0010171 2 0.022
organic hydroxy compound biosynthetic process GO:1901617 21 0.022
axon guidance GO:0007411 233 0.022
Fly
homeostatic process GO:0042592 199 0.022
biological adhesion GO:0022610 138 0.022
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.022
gland morphogenesis GO:0022612 145 0.022
heterocycle catabolic process GO:0046700 166 0.022
camera type eye development GO:0043010 4 0.022
regulation of transport GO:0051049 181 0.022
growth GO:0040007 359 0.022
epithelial cell differentiation GO:0030855 322 0.021
Fly
single organism intracellular transport GO:1902582 207 0.021
response to light stimulus GO:0009416 124 0.021
Fly
protein localization GO:0008104 284 0.021
positive regulation of gene expression GO:0010628 290 0.021
cellular protein modification process GO:0006464 438 0.021
cellular response to radiation GO:0071478 52 0.021
cellular amine metabolic process GO:0044106 12 0.021
Fly
regulation of catalytic activity GO:0050790 185 0.021
regulation of molecular function GO:0065009 217 0.020
cellular macromolecule localization GO:0070727 220 0.020
regulation of developmental growth GO:0048638 174 0.020
macromolecular complex assembly GO:0065003 256 0.020
lateral inhibition GO:0046331 206 0.020
autophagic cell death GO:0048102 83 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
oxidation reduction process GO:0055114 123 0.020
pigmentation GO:0043473 75 0.020
lipid localization GO:0010876 54 0.020
Fly
drinking behavior GO:0042756 2 0.019
aging GO:0007568 143 0.019
Fly
intracellular protein transmembrane transport GO:0065002 4 0.019
maintenance of location GO:0051235 73 0.019
Fly
immune effector process GO:0002252 98 0.019
detection of external stimulus GO:0009581 66 0.019
response to fungus GO:0009620 50 0.019
open tracheal system development GO:0007424 204 0.019
Fly
axonogenesis GO:0007409 290 0.019
Fly
positive regulation of cell communication GO:0010647 250 0.019
intracellular signal transduction GO:0035556 300 0.019
lipid catabolic process GO:0016042 21 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
nuclear division GO:0000280 332 0.018
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
cell proliferation GO:0008283 299 0.018
response to organic cyclic compound GO:0014070 89 0.018
protein transmembrane transport GO:0071806 4 0.018
negative regulation of gene expression GO:0010629 387 0.018
terpenoid metabolic process GO:0006721 7 0.018
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.018
respiratory system development GO:0060541 213 0.018
Fly
epithelial cell development GO:0002064 274 0.018
Fly
response to organonitrogen compound GO:0010243 75 0.018
response to glucose GO:0009749 2 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
intracellular transport GO:0046907 228 0.018
response to radiation GO:0009314 155 0.018
Fly
amine metabolic process GO:0009308 12 0.017
Fly
detection of abiotic stimulus GO:0009582 66 0.017
protein transport GO:0015031 155 0.017
lipid biosynthetic process GO:0008610 46 0.017
chromosome segregation GO:0007059 157 0.017
Fly
positive regulation of signal transduction GO:0009967 223 0.017
response to mercury ion GO:0046689 3 0.017
positive regulation of signaling GO:0023056 243 0.017
acetylcholine metabolic process GO:0008291 2 0.017
Fly
salivary gland histolysis GO:0035070 88 0.017
eye pigment metabolic process GO:0042441 33 0.017
spermatid differentiation GO:0048515 114 0.017
Fly
adult behavior GO:0030534 137 0.017
male gamete generation GO:0048232 201 0.017
Fly
purine containing compound metabolic process GO:0072521 155 0.017
synaptic transmission GO:0007268 288 0.017
Fly
acylglycerol catabolic process GO:0046464 3 0.016
cellular response to organic substance GO:0071310 132 0.016
regulation of growth GO:0040008 233 0.016
response to starvation GO:0042594 97 0.016
triglyceride catabolic process GO:0019433 3 0.016
cellular response to biotic stimulus GO:0071216 4 0.016
cellular hormone metabolic process GO:0034754 23 0.016
aggressive behavior GO:0002118 63 0.016
hormone biosynthetic process GO:0042446 20 0.016
benzene containing compound metabolic process GO:0042537 3 0.016
neuron recognition GO:0008038 101 0.016
Fly
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
small molecule biosynthetic process GO:0044283 37 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
apoptotic process GO:0006915 159 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
Fly
pigment biosynthetic process GO:0046148 36 0.015
organelle assembly GO:0070925 198 0.015
developmental pigmentation GO:0048066 68 0.015
monocarboxylic acid transport GO:0015718 3 0.015
regulation of cell cycle GO:0051726 291 0.015
forebrain development GO:0030900 2 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
pigment metabolic process involved in pigmentation GO:0043474 33 0.015
lipid storage GO:0019915 38 0.015
Fly
motor neuron axon guidance GO:0008045 58 0.015
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
response to nitrogen compound GO:1901698 90 0.015
cellular homeostasis GO:0019725 80 0.015
encapsulation of foreign target GO:0035010 38 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
positive regulation of cell migration GO:0030335 2 0.015
neurotransmitter catabolic process GO:0042135 1 0.015
Fly
glycerolipid catabolic process GO:0046503 3 0.014
chromosome organization GO:0051276 360 0.014
sterol homeostasis GO:0055092 4 0.014
detection of visible light GO:0009584 38 0.014
protein complex assembly GO:0006461 200 0.014
cell motility GO:0048870 251 0.014
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.014
cellularization GO:0007349 90 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
neutral lipid biosynthetic process GO:0046460 2 0.014
protein complex biogenesis GO:0070271 201 0.014
defense response to gram negative bacterium GO:0050829 94 0.014
ion transport GO:0006811 145 0.014
phosphorylation GO:0016310 294 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
gene silencing GO:0016458 138 0.014
mitotic nuclear division GO:0007067 213 0.014
regulation of vesicle mediated transport GO:0060627 59 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
axis specification GO:0009798 167 0.014
interspecies interaction between organisms GO:0044419 16 0.014
establishment of protein localization GO:0045184 163 0.014
immune response activating signal transduction GO:0002757 2 0.014
cellular response to abiotic stimulus GO:0071214 58 0.014
amine catabolic process GO:0009310 1 0.014
Fly
isoprenoid metabolic process GO:0006720 8 0.014
aromatic compound catabolic process GO:0019439 166 0.014
phototransduction visible light GO:0007603 27 0.014
cellular response to oxygen containing compound GO:1901701 79 0.014
ovarian follicle cell development GO:0030707 248 0.013
Fly
eye pigment biosynthetic process GO:0006726 32 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
localization of cell GO:0051674 257 0.013
Fly
chemical homeostasis GO:0048878 92 0.013
regulation of cell death GO:0010941 173 0.013
cellular protein localization GO:0034613 160 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
positive regulation of molecular function GO:0044093 136 0.013
nucleoside metabolic process GO:0009116 127 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
positive regulation of cell motility GO:2000147 3 0.013
neurotransmitter metabolic process GO:0042133 2 0.013
Fly
negative regulation of signaling GO:0023057 219 0.013
secretion GO:0046903 109 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
negative regulation of cell communication GO:0010648 223 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
connective tissue development GO:0061448 3 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
phenol containing compound metabolic process GO:0018958 57 0.013
feeding behavior GO:0007631 50 0.013
tissue morphogenesis GO:0048729 297 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of response to stress GO:0080134 200 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
ras protein signal transduction GO:0007265 88 0.012
blood circulation GO:0008015 26 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
spermatogenesis GO:0007283 200 0.012
Fly
nucleotide metabolic process GO:0009117 161 0.012
regulation of catabolic process GO:0009894 170 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
estrogen metabolic process GO:0008210 1 0.012
choline catabolic process GO:0042426 1 0.012
Fly
cholesterol homeostasis GO:0042632 3 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
macromolecule catabolic process GO:0009057 161 0.012
synaptic target recognition GO:0008039 45 0.012
Fly
epithelial cell migration GO:0010631 148 0.012
Fly
phagocytosis recognition GO:0006910 1 0.012
regulation of endocytosis GO:0030100 37 0.012
sleep GO:0030431 49 0.012
negative regulation of female receptivity post mating GO:0045434 12 0.012
circadian rhythm GO:0007623 105 0.012
transmembrane transport GO:0055085 139 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
storage protein import into fat body GO:0015032 2 0.012
negative regulation of signal transduction GO:0009968 206 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
developmental maturation GO:0021700 172 0.012
melanization defense response GO:0035006 45 0.012
regulation of cell proliferation GO:0042127 163 0.012
choline metabolic process GO:0019695 1 0.011
Fly
regulation of hormone levels GO:0010817 40 0.011
segmentation GO:0035282 207 0.011
limb development GO:0060173 1 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
carbohydrate metabolic process GO:0005975 82 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
rna processing GO:0006396 147 0.011
tube development GO:0035295 244 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
alpha amino acid metabolic process GO:1901605 20 0.011
intracellular protein transmembrane import GO:0044743 4 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
small molecule catabolic process GO:0044282 21 0.011
Fly
regulation of system process GO:0044057 36 0.011
spermatid development GO:0007286 98 0.011
cell adhesion GO:0007155 136 0.011
Fly
alcohol metabolic process GO:0006066 25 0.011
Fly
dorsal ventral pattern formation GO:0009953 133 0.011
negative regulation of developmental process GO:0051093 201 0.011
regulation of tube size GO:0035150 46 0.011
Fly
establishment of blood nerve barrier GO:0008065 2 0.011
Fly
blastoderm segmentation GO:0007350 159 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
rhythmic process GO:0048511 106 0.011
organic hydroxy compound catabolic process GO:1901616 4 0.011
Fly
very long chain fatty acid metabolic process GO:0000038 4 0.011
response to copper ion GO:0046688 4 0.011
melanotic encapsulation of foreign target GO:0035011 30 0.011
neutral lipid catabolic process GO:0046461 3 0.011
positive regulation of catabolic process GO:0009896 105 0.011
detection of external biotic stimulus GO:0098581 2 0.011
male mating behavior GO:0060179 70 0.011
Fly
purine nucleotide metabolic process GO:0006163 146 0.011
hindbrain development GO:0030902 2 0.011
regulation of blood circulation GO:1903522 21 0.011
response to hexose GO:0009746 3 0.011
regulation of organelle organization GO:0033043 196 0.011
mitotic spindle organization GO:0007052 220 0.011
regulation of sequestering of triglyceride GO:0010889 3 0.011
cell migration GO:0016477 238 0.011
Fly
circulatory system process GO:0003013 37 0.011
regulation of protein metabolic process GO:0051246 256 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
intracellular protein transport GO:0006886 104 0.011
camera type eye morphogenesis GO:0048593 2 0.011
retina development in camera type eye GO:0060041 4 0.011
multicellular organismal aging GO:0010259 140 0.011
Fly
negative regulation of rna metabolic process GO:0051253 251 0.011
detection of light stimulus GO:0009583 58 0.011
notch signaling pathway GO:0007219 120 0.010
monocarboxylic acid metabolic process GO:0032787 29 0.010
wound healing GO:0042060 75 0.010
protein import GO:0017038 55 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
melanin metabolic process GO:0006582 47 0.010
defense response to fungus GO:0050832 48 0.010
positive regulation of lipid metabolic process GO:0045834 4 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
cell division GO:0051301 248 0.010
circadian sleep wake cycle GO:0042745 28 0.010
telencephalon development GO:0021537 2 0.010
response to monosaccharide GO:0034284 4 0.010
response to endogenous stimulus GO:0009719 119 0.010
ameboidal type cell migration GO:0001667 151 0.010
Fly
positive regulation of rna metabolic process GO:0051254 271 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
regulation of lipid transport GO:0032368 3 0.010
mrna metabolic process GO:0016071 124 0.010
chaeta development GO:0022416 97 0.010
dna metabolic process GO:0006259 227 0.010

alpha-Est2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
hypertension DOID:10763 0 0.043
artery disease DOID:0050828 0 0.043
vascular disease DOID:178 0 0.043
essential hypertension DOID:10825 0 0.043
cardiovascular system disease DOID:1287 0 0.043
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
neurodegenerative disease DOID:1289 0 0.011
musculoskeletal system disease DOID:17 0 0.011