Drosophila melanogaster

26 known processes

Aps (Dmel_CG6391)

CG6391 gene product from transcript CG6391-RC

(Aliases: Dmel\CG6391,anon-WO0118547.266,CG6391)

Aps biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.211
small molecule metabolic process GO:0044281 305 0.177
cell division GO:0051301 248 0.168
cell proliferation GO:0008283 299 0.118
regulation of response to stress GO:0080134 200 0.112
organic substance catabolic process GO:1901575 308 0.105
Yeast
nucleoside phosphate metabolic process GO:0006753 162 0.105
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.100
response to biotic stimulus GO:0009607 294 0.100
dna metabolic process GO:0006259 227 0.097
heterocycle catabolic process GO:0046700 166 0.096
Yeast
brain development GO:0007420 120 0.091
programmed cell death GO:0012501 257 0.086
head development GO:0060322 135 0.083
chromosome organization GO:0051276 360 0.081
negative regulation of developmental process GO:0051093 201 0.081
cellular catabolic process GO:0044248 372 0.080
Yeast
protein modification process GO:0036211 438 0.075
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.073
cellular response to light stimulus GO:0071482 37 0.072
regulation of intracellular signal transduction GO:1902531 236 0.071
regulation of multicellular organismal development GO:2000026 414 0.071
nucleosome assembly GO:0006334 35 0.071
death GO:0016265 284 0.069
intracellular signal transduction GO:0035556 300 0.068
cellular nitrogen compound catabolic process GO:0044270 165 0.067
Yeast
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.067
purine ribonucleotide metabolic process GO:0009150 145 0.067
appendage development GO:0048736 401 0.066
negative regulation of transcription dna templated GO:0045892 237 0.065
stem cell differentiation GO:0048863 117 0.062
organic substance transport GO:0071702 257 0.062
negative regulation of gene expression GO:0010629 387 0.061
regulation of neurogenesis GO:0050767 158 0.061
chromatin assembly GO:0031497 48 0.061
macromolecular complex assembly GO:0065003 256 0.060
negative regulation of cellular biosynthetic process GO:0031327 277 0.060
lateral inhibition GO:0046331 206 0.060
organonitrogen compound metabolic process GO:1901564 318 0.060
chromatin assembly or disassembly GO:0006333 52 0.059
rna processing GO:0006396 147 0.059
negative regulation of biosynthetic process GO:0009890 277 0.059
mrna splicing via spliceosome GO:0000398 73 0.057
response to other organism GO:0051707 293 0.057
aromatic compound catabolic process GO:0019439 166 0.056
Yeast
nucleobase containing compound catabolic process GO:0034655 165 0.055
Yeast
regulation of cellular localization GO:0060341 136 0.053
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.053
response to abiotic stimulus GO:0009628 341 0.052
response to external biotic stimulus GO:0043207 293 0.052
gliogenesis GO:0042063 80 0.051
appendage morphogenesis GO:0035107 397 0.051
regulation of multi organism process GO:0043900 131 0.050
dna packaging GO:0006323 91 0.049
digestive tract development GO:0048565 149 0.049
regulation of phosphorus metabolic process GO:0051174 210 0.049
post embryonic appendage morphogenesis GO:0035120 385 0.049
endocytosis GO:0006897 310 0.049
positive regulation of response to stimulus GO:0048584 323 0.047
nucleosome organization GO:0034728 59 0.047
imaginal disc derived wing morphogenesis GO:0007476 337 0.047
imaginal disc derived appendage development GO:0048737 399 0.046
regulation of immune system process GO:0002682 176 0.046
cellular protein modification process GO:0006464 438 0.045
nucleobase containing small molecule metabolic process GO:0055086 174 0.045
protein ubiquitination GO:0016567 70 0.043
negative regulation of rna biosynthetic process GO:1902679 240 0.041
positive regulation of nervous system development GO:0051962 69 0.041
regulation of localization GO:0032879 275 0.040
mrna metabolic process GO:0016071 124 0.039
regulation of mrna processing GO:0050684 71 0.038
positive regulation of signal transduction GO:0009967 223 0.038
nucleotide metabolic process GO:0009117 161 0.037
gene silencing by rna GO:0031047 57 0.037
ribonucleoside metabolic process GO:0009119 127 0.037
purine nucleotide metabolic process GO:0006163 146 0.037
ribose phosphate metabolic process GO:0019693 145 0.037
establishment of localization in cell GO:0051649 402 0.036
regulation of mrna splicing via spliceosome GO:0048024 64 0.036
regulation of nervous system development GO:0051960 248 0.035
wing disc morphogenesis GO:0007472 344 0.035
aggressive behavior GO:0002118 63 0.035
regulation of rna splicing GO:0043484 69 0.034
regulation of cell differentiation GO:0045595 302 0.034
carbohydrate derivative metabolic process GO:1901135 217 0.034
guanosine containing compound metabolic process GO:1901068 74 0.034
regulation of immune response GO:0050776 118 0.033
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
neurological system process GO:0050877 358 0.032
regulation of protein modification process GO:0031399 112 0.032
negative regulation of cell communication GO:0010648 223 0.032
negative regulation of cellular metabolic process GO:0031324 382 0.032
immune system process GO:0002376 347 0.032
regulation of protein metabolic process GO:0051246 256 0.032
cell motility GO:0048870 251 0.031
regulation of cell development GO:0060284 215 0.031
negative regulation of signal transduction GO:0009968 206 0.031
immune response GO:0006955 246 0.031
ribonucleotide metabolic process GO:0009259 145 0.031
positive regulation of signaling GO:0023056 243 0.030
protein modification by small protein conjugation GO:0032446 79 0.030
positive regulation of catalytic activity GO:0043085 118 0.030
response to oxygen containing compound GO:1901700 200 0.030
purine nucleoside metabolic process GO:0042278 127 0.030
negative regulation of response to stimulus GO:0048585 258 0.030
defense response to other organism GO:0098542 225 0.030
leg disc development GO:0035218 92 0.029
cellularization GO:0007349 90 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
cellular response to radiation GO:0071478 52 0.029
positive regulation of hydrolase activity GO:0051345 78 0.029
regulation of pole plasm oskar mrna localization GO:0007317 27 0.029
regulation of synapse assembly GO:0051963 94 0.029
glial cell migration GO:0008347 31 0.029
organophosphate metabolic process GO:0019637 195 0.028
response to alcohol GO:0097305 95 0.028
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
cellular component assembly involved in morphogenesis GO:0010927 151 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
synapse assembly GO:0007416 143 0.028
cytoplasmic transport GO:0016482 130 0.028
intracellular transport GO:0046907 228 0.028
negative regulation of cellular component organization GO:0051129 108 0.028
central nervous system development GO:0007417 201 0.027
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.027
organic cyclic compound catabolic process GO:1901361 168 0.027
Yeast
behavioral response to ethanol GO:0048149 49 0.027
ribonucleotide catabolic process GO:0009261 109 0.027
mrna processing GO:0006397 104 0.027
cell migration GO:0016477 238 0.027
nucleoside phosphate catabolic process GO:1901292 110 0.027
Yeast
dna conformation change GO:0071103 105 0.027
ribonucleoside triphosphate metabolic process GO:0009199 119 0.027
protein modification by small protein conjugation or removal GO:0070647 106 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
purine nucleoside triphosphate catabolic process GO:0009146 108 0.026
cell death GO:0008219 279 0.026
nucleoside metabolic process GO:0009116 127 0.025
regulation of molecular function GO:0065009 217 0.025
positive regulation of biosynthetic process GO:0009891 316 0.025
regulation of cell cycle GO:0051726 291 0.024
regulation of response to external stimulus GO:0032101 115 0.024
positive regulation of cell communication GO:0010647 250 0.024
adult behavior GO:0030534 137 0.024
purine nucleoside catabolic process GO:0006152 112 0.024
nucleotide catabolic process GO:0009166 109 0.024
Yeast
neuroblast proliferation GO:0007405 74 0.024
amine metabolic process GO:0009308 12 0.024
response to decreased oxygen levels GO:0036293 58 0.023
nucleoside catabolic process GO:0009164 112 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
glycosyl compound catabolic process GO:1901658 112 0.022
rna splicing via transesterification reactions GO:0000375 73 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
glycosyl compound metabolic process GO:1901657 127 0.022
catabolic process GO:0009056 409 0.022
Yeast
regulation of protein kinase activity GO:0045859 51 0.022
detection of stimulus GO:0051606 156 0.022
germarium derived egg chamber formation GO:0007293 101 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
regulation of phosphorylation GO:0042325 147 0.022
stem cell division GO:0017145 69 0.022
defense response GO:0006952 300 0.022
phagocytosis GO:0006909 215 0.022
response to organic substance GO:0010033 284 0.021
negative regulation of signaling GO:0023057 219 0.021
localization of cell GO:0051674 257 0.021
purine ribonucleoside metabolic process GO:0046128 127 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
chromatin organization GO:0006325 207 0.021
regulation of cytoskeleton organization GO:0051493 89 0.020
response to hypoxia GO:0001666 53 0.020
positive regulation of immune system process GO:0002684 68 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
regulation of axon extension involved in axon guidance GO:0048841 4 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
gtp metabolic process GO:0046039 72 0.020
leg disc morphogenesis GO:0007478 80 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
developmental maturation GO:0021700 172 0.020
negative regulation of protein metabolic process GO:0051248 85 0.020
body morphogenesis GO:0010171 2 0.019
rna splicing GO:0008380 83 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
axon development GO:0061564 297 0.019
gtp catabolic process GO:0006184 72 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
embryonic heart tube development GO:0035050 22 0.019
ras protein signal transduction GO:0007265 88 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
macromolecule catabolic process GO:0009057 161 0.019
regulation of cell cycle process GO:0010564 181 0.019
mapk cascade GO:0000165 107 0.019
regulation of mrna metabolic process GO:1903311 72 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
chemotaxis GO:0006935 249 0.019
regulation of oocyte development GO:0060281 27 0.019
methylation GO:0032259 47 0.018
dendrite development GO:0016358 204 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
cellular amine metabolic process GO:0044106 12 0.018
purine containing compound metabolic process GO:0072521 155 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
protein dna complex subunit organization GO:0071824 86 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
locomotory behavior GO:0007626 176 0.018
vesicle mediated transport GO:0016192 381 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
single organism biosynthetic process GO:0044711 206 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
neuronal stem cell division GO:0036445 35 0.017
apoptotic process GO:0006915 159 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
establishment of protein localization GO:0045184 163 0.017
regulation of organelle organization GO:0033043 196 0.016
segmentation GO:0035282 207 0.016
regulation of hydrolase activity GO:0051336 97 0.016
mesenchymal cell development GO:0014031 1 0.016
positive regulation of mitotic cell cycle GO:0045931 34 0.016
chromatin modification GO:0016568 147 0.016
histone modification GO:0016570 106 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
negative regulation of immune system process GO:0002683 50 0.016
positive regulation of developmental process GO:0051094 143 0.016
centrosome organization GO:0051297 163 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
single organism catabolic process GO:0044712 228 0.016
Yeast
positive regulation of cellular component organization GO:0051130 156 0.016
oocyte differentiation GO:0009994 145 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
posttranscriptional gene silencing GO:0016441 46 0.016
regulation of neuron differentiation GO:0045664 103 0.016
regulation of behavior GO:0050795 75 0.016
drinking behavior GO:0042756 2 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
response to sterol GO:0036314 34 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of innate immune response GO:0045088 71 0.015
regulation of transport GO:0051049 181 0.015
dendrite morphogenesis GO:0048813 199 0.015
cellular protein localization GO:0034613 160 0.015
tube morphogenesis GO:0035239 191 0.015
meiotic cell cycle GO:0051321 171 0.015
ovarian follicle cell development GO:0030707 248 0.015
protein localization GO:0008104 284 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
alternative mrna splicing via spliceosome GO:0000380 60 0.015
epithelial cell differentiation GO:0030855 322 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
multicellular organismal aging GO:0010259 140 0.014
muscle cell differentiation GO:0042692 103 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
mating GO:0007618 120 0.014
regulation of nucleocytoplasmic transport GO:0046822 35 0.014
cellular response to decreased oxygen levels GO:0036294 30 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
response to ethanol GO:0045471 59 0.014
determination of adult lifespan GO:0008340 137 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.014
microtubule organizing center organization GO:0031023 168 0.014
phosphorylation GO:0016310 294 0.014
negative regulation of response to external stimulus GO:0032102 22 0.014
renal filtration cell differentiation GO:0061318 12 0.014
neuron projection guidance GO:0097485 241 0.013
homeostatic process GO:0042592 199 0.013
embryonic pattern specification GO:0009880 174 0.013
germ line stem cell maintenance GO:0030718 50 0.013
organelle localization GO:0051640 148 0.013
purine containing compound catabolic process GO:0072523 112 0.013
regulation of embryonic development GO:0045995 68 0.013
muscle organ development GO:0007517 127 0.013
rna localization GO:0006403 115 0.013
response to radiation GO:0009314 155 0.013
immune response activating signal transduction GO:0002757 2 0.013
regulation of defense response GO:0031347 102 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
regulation of apoptotic process GO:0042981 130 0.013
positive regulation of catabolic process GO:0009896 105 0.013
eye morphogenesis GO:0048592 260 0.013
oxoacid metabolic process GO:0043436 103 0.013
Yeast
asymmetric neuroblast division GO:0055059 33 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
cellular macromolecule localization GO:0070727 220 0.013
inter male aggressive behavior GO:0002121 60 0.013
regulation of cellular response to stress GO:0080135 89 0.012
respiratory system development GO:0060541 213 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
neuroblast division GO:0055057 35 0.012
mitotic spindle organization GO:0007052 220 0.012
response to oxygen levels GO:0070482 59 0.012
actin cytoskeleton organization GO:0030036 206 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
rhythmic behavior GO:0007622 76 0.012
regulation of proteolysis GO:0030162 87 0.012
translation GO:0006412 69 0.012
mitotic nuclear division GO:0007067 213 0.012
circadian rhythm GO:0007623 105 0.012
single organism intracellular transport GO:1902582 207 0.012
negative regulation of nervous system development GO:0051961 92 0.012
protein complex assembly GO:0006461 200 0.012
oocyte development GO:0048599 124 0.012
stem cell development GO:0048864 79 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
protein transport GO:0015031 155 0.011
regionalization GO:0003002 416 0.011
male gamete generation GO:0048232 201 0.011
response to extracellular stimulus GO:0009991 116 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
positive regulation of molecular function GO:0044093 136 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
positive regulation of cell development GO:0010720 61 0.011
neural precursor cell proliferation GO:0061351 75 0.011
aging GO:0007568 143 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
single organism behavior GO:0044708 391 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
negative regulation of developmental growth GO:0048640 64 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of lipid transport GO:0032368 3 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
cell aging GO:0007569 2 0.011
multi organism behavior GO:0051705 175 0.011
histone lysine methylation GO:0034968 32 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of dna metabolic process GO:0051052 34 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
photoreceptor cell development GO:0042461 96 0.011
organic acid metabolic process GO:0006082 103 0.011
Yeast
posttranscriptional gene silencing by rna GO:0035194 45 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
oocyte construction GO:0007308 112 0.010
negative regulation of protein phosphorylation GO:0001933 17 0.010
imaginal disc derived leg morphogenesis GO:0007480 80 0.010
protein dna complex assembly GO:0065004 63 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
rhythmic process GO:0048511 106 0.010
germ line stem cell division GO:0042078 25 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
negative regulation of defense response GO:0031348 35 0.010
humoral immune response GO:0006959 117 0.010
spermatid differentiation GO:0048515 114 0.010
regulation of actin cytoskeleton organization GO:0032956 42 0.010

Aps disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015