Drosophila melanogaster

5 known processes

CG42640 (Dmel_CG42640)

CG42640 gene product from transcript CG42640-RA

(Aliases: proPO59,Dox-A3,CG2952,DmePPO3,Dmel\CG42640,PPO3,Dmel_CG2952,Pro-PO3)

CG42640 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 381 0.064
response to monosaccharide GO:0034284 4 0.057
transition metal ion transport GO:0000041 16 0.055
organonitrogen compound metabolic process GO:1901564 318 0.051
establishment of localization in cell GO:0051649 402 0.047
small molecule metabolic process GO:0044281 305 0.042
transmembrane transport GO:0055085 139 0.041
cellular catabolic process GO:0044248 372 0.041
cell proliferation GO:0008283 299 0.040
ion transport GO:0006811 145 0.040
catabolic process GO:0009056 409 0.039
adult behavior GO:0030534 137 0.038
transcription from rna polymerase ii promoter GO:0006366 368 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.037
positive regulation of nucleic acid templated transcription GO:1903508 266 0.036
metal ion transport GO:0030001 74 0.036
negative regulation of gene expression GO:0010629 387 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
organic substance transport GO:0071702 257 0.035
transition metal ion homeostasis GO:0055076 17 0.034
g protein coupled receptor signaling pathway GO:0007186 136 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.033
kidney development GO:0001822 3 0.033
neurological system process GO:0050877 358 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
purine containing compound metabolic process GO:0072521 155 0.031
regulation of cellular amine metabolic process GO:0033238 3 0.031
endocytosis GO:0006897 310 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
positive regulation of gene expression GO:0010628 290 0.030
response to hexose GO:0009746 3 0.030
response to glucose GO:0009749 2 0.030
organic substance catabolic process GO:1901575 308 0.029
cation transport GO:0006812 110 0.028
wing disc morphogenesis GO:0007472 344 0.028
protein modification process GO:0036211 438 0.027
appendage development GO:0048736 401 0.027
locomotory behavior GO:0007626 176 0.027
response to organic substance GO:0010033 284 0.027
single organism behavior GO:0044708 391 0.027
cation transmembrane transport GO:0098655 88 0.027
regulation of localization GO:0032879 275 0.026
nucleobase containing compound catabolic process GO:0034655 165 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
positive regulation of biosynthetic process GO:0009891 316 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
epithelial cell differentiation GO:0030855 322 0.024
regulation of cell differentiation GO:0045595 302 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
regulation of protein metabolic process GO:0051246 256 0.024
regulation of cell cycle GO:0051726 291 0.024
negative regulation of calcium ion import GO:0090281 2 0.024
response to oxygen containing compound GO:1901700 200 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
cellular protein modification process GO:0006464 438 0.023
negative regulation of rna metabolic process GO:0051253 251 0.023
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
phosphorylation GO:0016310 294 0.023
chemical homeostasis GO:0048878 92 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
appendage morphogenesis GO:0035107 397 0.023
single organism catabolic process GO:0044712 228 0.023
oxoacid metabolic process GO:0043436 103 0.022
aromatic compound catabolic process GO:0019439 166 0.022
phagocytosis GO:0006909 215 0.022
macromolecular complex assembly GO:0065003 256 0.022
response to lipopolysaccharide GO:0032496 4 0.022
cellular ketone metabolic process GO:0042180 24 0.022
ion homeostasis GO:0050801 55 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
heterocycle catabolic process GO:0046700 166 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
organonitrogen compound biosynthetic process GO:1901566 117 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
establishment or maintenance of cell polarity GO:0007163 167 0.021
intracellular signal transduction GO:0035556 300 0.021
regulation of cell proliferation GO:0042127 163 0.021
inorganic cation transmembrane transport GO:0098662 61 0.021
single organism biosynthetic process GO:0044711 206 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
forebrain development GO:0030900 2 0.020
cell death GO:0008219 279 0.020
ion transmembrane transport GO:0034220 122 0.020
response to nutrient levels GO:0031667 114 0.020
negative regulation of cell differentiation GO:0045596 143 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
homeostatic process GO:0042592 199 0.020
positive regulation of signaling GO:0023056 243 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
regulation of programmed cell death GO:0043067 152 0.020
immune system process GO:0002376 347 0.020
embryonic pattern specification GO:0009880 174 0.019
determination of adult lifespan GO:0008340 137 0.019
cell division GO:0051301 248 0.019
regulation of cell cycle process GO:0010564 181 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
adult locomotory behavior GO:0008344 76 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
organelle fission GO:0048285 340 0.019
regulation of transport GO:0051049 181 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.018
organic acid metabolic process GO:0006082 103 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
nucleoside triphosphate metabolic process GO:0009141 120 0.018
axis specification GO:0009798 167 0.018
peptide metabolic process GO:0006518 80 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
regulation of vesicle mediated transport GO:0060627 59 0.018
macromolecule catabolic process GO:0009057 161 0.018
proteolysis GO:0006508 192 0.018
cellular amine metabolic process GO:0044106 12 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
regulation of epithelial cell proliferation GO:0050678 4 0.018
body morphogenesis GO:0010171 2 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
regionalization GO:0003002 416 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
positive regulation of cell communication GO:0010647 250 0.017
phenol containing compound metabolic process GO:0018958 57 0.017
endomembrane system organization GO:0010256 119 0.017
organophosphate metabolic process GO:0019637 195 0.017
response to alcohol GO:0097305 95 0.017
compound eye morphogenesis GO:0001745 249 0.017
secretion by cell GO:0032940 101 0.017
sterol homeostasis GO:0055092 4 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
regulation of catalytic activity GO:0050790 185 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
chromosome organization GO:0051276 360 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
death GO:0016265 284 0.016
single organism intracellular transport GO:1902582 207 0.016
secretion GO:0046903 109 0.016
nitrogen compound transport GO:0071705 85 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
response to abiotic stimulus GO:0009628 341 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
response to extracellular stimulus GO:0009991 116 0.016
regulation of immune system process GO:0002682 176 0.016
connective tissue development GO:0061448 3 0.016
stem cell differentiation GO:0048863 117 0.016
l amino acid import GO:0043092 2 0.016
response to biotic stimulus GO:0009607 294 0.016
inorganic ion transmembrane transport GO:0098660 73 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
cell motility GO:0048870 251 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
carbohydrate metabolic process GO:0005975 82 0.016
negative regulation of signal transduction GO:0009968 206 0.016
positive regulation of signal transduction GO:0009967 223 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
cytoplasmic transport GO:0016482 130 0.015
nucleotide metabolic process GO:0009117 161 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
metal ion homeostasis GO:0055065 44 0.015
response to bacterium GO:0009617 198 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
regulation of hydrolase activity GO:0051336 97 0.015
aging GO:0007568 143 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
protein phosphorylation GO:0006468 169 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
protein transport GO:0015031 155 0.014
epithelial cell development GO:0002064 274 0.014
compound eye development GO:0048749 307 0.014
camera type eye development GO:0043010 4 0.014
apoptotic process GO:0006915 159 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
cholesterol homeostasis GO:0042632 3 0.014
growth GO:0040007 359 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
regulation of cell death GO:0010941 173 0.014
eye development GO:0001654 323 0.014
blastoderm segmentation GO:0007350 159 0.014
response to external biotic stimulus GO:0043207 293 0.014
defense response GO:0006952 300 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
programmed cell death GO:0012501 257 0.014
taxis GO:0042330 304 0.014
intracellular transport GO:0046907 228 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
cholesterol transport GO:0030301 2 0.014
production of molecular mediator of immune response GO:0002440 46 0.014
response to wounding GO:0009611 94 0.014
regulation of cell development GO:0060284 215 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.013
positive regulation of transport GO:0051050 92 0.013
nucleoside metabolic process GO:0009116 127 0.013
skeletal muscle fiber development GO:0048741 3 0.013
exocrine system development GO:0035272 162 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
male gamete generation GO:0048232 201 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
cellular homeostasis GO:0019725 80 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
nuclear division GO:0000280 332 0.013
regulation of proteolysis GO:0030162 87 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
regulation of molecular function GO:0065009 217 0.013
protein localization GO:0008104 284 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
amide biosynthetic process GO:0043604 42 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
retina development in camera type eye GO:0060041 4 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
spermatogenesis GO:0007283 200 0.013
multicellular organismal aging GO:0010259 140 0.013
eye morphogenesis GO:0048592 260 0.013
innate immune response GO:0045087 144 0.013
zinc ion transport GO:0006829 5 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
cation homeostasis GO:0055080 51 0.013
chromatin modification GO:0016568 147 0.013
protein processing GO:0016485 68 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
tube morphogenesis GO:0035239 191 0.012
gene silencing GO:0016458 138 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
cellular transition metal ion homeostasis GO:0046916 9 0.012
developmental programmed cell death GO:0010623 138 0.012
amine metabolic process GO:0009308 12 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
actin cytoskeleton organization GO:0030036 206 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
regulation of apoptotic process GO:0042981 130 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
anterior posterior axis specification GO:0009948 109 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
gastrulation involving germ band extension GO:0010004 36 0.012
digestive tract development GO:0048565 149 0.012
positive regulation of developmental process GO:0051094 143 0.012
response to copper ion GO:0046688 4 0.012
antimicrobial humoral response GO:0019730 99 0.012
regulation of lipid transport GO:0032368 3 0.012
ovarian follicle cell development GO:0030707 248 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.012
anterior posterior pattern specification GO:0009952 136 0.012
response to other organism GO:0051707 293 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
chromatin remodeling GO:0006338 72 0.012
nucleoside catabolic process GO:0009164 112 0.012
digestive tract morphogenesis GO:0048546 127 0.012
positive regulation of cell migration GO:0030335 2 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
response to radiation GO:0009314 155 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
negative regulation of developmental process GO:0051093 201 0.011
immune response activating signal transduction GO:0002757 2 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
response to starvation GO:0042594 97 0.011
regulation of catabolic process GO:0009894 170 0.011
ras protein signal transduction GO:0007265 88 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
regulation of phosphorylation GO:0042325 147 0.011
gastrulation with mouth forming first GO:0001703 36 0.011
kidney morphogenesis GO:0060993 3 0.011
ameboidal type cell migration GO:0001667 151 0.011
central nervous system development GO:0007417 201 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
mesenchymal cell development GO:0014031 1 0.011
sensory perception of smell GO:0007608 80 0.011
endoderm formation GO:0001706 3 0.011
mitotic spindle organization GO:0007052 220 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
organophosphate catabolic process GO:0046434 112 0.011
hemopoiesis GO:0030097 46 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
chemosensory behavior GO:0007635 106 0.011
cellular cation homeostasis GO:0030003 38 0.011
photoreceptor cell development GO:0042461 96 0.011
negative regulation of cell communication GO:0010648 223 0.011
cell cycle checkpoint GO:0000075 95 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
regulation of organelle organization GO:0033043 196 0.011
dna metabolic process GO:0006259 227 0.011
dna integrity checkpoint GO:0031570 81 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
associative learning GO:0008306 65 0.011
purine containing compound catabolic process GO:0072523 112 0.011
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.011
erbb signaling pathway GO:0038127 58 0.011
protein maturation GO:0051604 71 0.011
cellular response to organic substance GO:0071310 132 0.010
mitotic nuclear division GO:0007067 213 0.010
positive regulation of catabolic process GO:0009896 105 0.010
spindle organization GO:0007051 253 0.010
immune response GO:0006955 246 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
regulation of secretion GO:0051046 44 0.010
regulation of immune response GO:0050776 118 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
hormone catabolic process GO:0042447 3 0.010
sensory organ morphogenesis GO:0090596 260 0.010
imaginal disc pattern formation GO:0007447 91 0.010
zinc ion transmembrane transport GO:0071577 5 0.010
regulation of organ morphogenesis GO:2000027 78 0.010
humoral immune response GO:0006959 117 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
segmentation GO:0035282 207 0.010
regulation of response to stress GO:0080134 200 0.010
regulation of mapk cascade GO:0043408 92 0.010
cellular response to dna damage stimulus GO:0006974 223 0.010
positive regulation of cell differentiation GO:0045597 64 0.010
antimicrobial peptide production GO:0002775 46 0.010
gland morphogenesis GO:0022612 145 0.010

CG42640 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.066
acquired metabolic disease DOID:0060158 0 0.066
diabetes mellitus DOID:9351 0 0.040
carbohydrate metabolism disease DOID:0050013 0 0.040
glucose metabolism disease DOID:4194 0 0.040
type 2 diabetes mellitus DOID:9352 0 0.040
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.013
cardiovascular system disease DOID:1287 0 0.012
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.010