|
|
dna metabolic process
|
GO:0006259 |
227 |
0.999
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
116 |
0.997
|
Human Zebrafish Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
16 |
0.996
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
103 |
0.995
|
Human Mouse |
|
|
chromosome organization
|
GO:0051276 |
360 |
0.994
|
Human Mouse |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.993
|
Human Zebrafish Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
223 |
0.991
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
27 |
0.991
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.985
|
Mouse |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.984
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.984
|
Human Zebrafish Mouse |
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.982
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
11 |
0.977
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.977
|
Human Zebrafish Mouse |
|
|
response to radiation
|
GO:0009314 |
155 |
0.970
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.967
|
Human Zebrafish Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.960
|
Human Mouse |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
109 |
0.959
|
Human Mouse |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.954
|
|
|
|
response to organic substance
|
GO:0010033 |
284 |
0.950
|
Zebrafish Mouse |
|
|
programmed cell death
|
GO:0012501 |
257 |
0.945
|
|
|
|
double strand break repair
|
GO:0006302 |
26 |
0.944
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
130 |
0.936
|
Human Mouse |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
109 |
0.928
|
Human Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.927
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
88 |
0.923
|
Human Mouse |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
74 |
0.920
|
Human Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
36 |
0.912
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.908
|
Human Mouse |
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.899
|
|
|
|
axonogenesis
|
GO:0007409 |
290 |
0.895
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.893
|
Zebrafish Mouse Worm |
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.891
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.888
|
Human Zebrafish Mouse |
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.879
|
Mouse |
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.875
|
Human Zebrafish Mouse |
|
|
neuron death
|
GO:0070997 |
27 |
0.869
|
Zebrafish Mouse |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.861
|
|
|
|
cell growth
|
GO:0016049 |
108 |
0.857
|
Human |
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.852
|
Human Zebrafish Mouse |
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.852
|
|
|
|
telomere organization
|
GO:0032200 |
21 |
0.849
|
|
|
|
regulation of macroautophagy
|
GO:0016241 |
15 |
0.842
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.841
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
128 |
0.837
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.837
|
Mouse |
|
|
axon development
|
GO:0061564 |
297 |
0.821
|
|
|
|
dna packaging
|
GO:0006323 |
91 |
0.815
|
Human |
|
|
catabolic process
|
GO:0009056 |
409 |
0.815
|
|
|
|
positive regulation of macroautophagy
|
GO:0016239 |
8 |
0.804
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
59 |
0.799
|
Worm |
|
|
gene silencing
|
GO:0016458 |
138 |
0.796
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.795
|
|
|
|
ectopic germ cell programmed cell death
|
GO:0035234 |
8 |
0.789
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
75 |
0.785
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.775
|
Human Mouse |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
3 |
0.773
|
Human Zebrafish Mouse |
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.772
|
Human Zebrafish Mouse |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
103 |
0.771
|
Human Mouse |
|
|
protein modification process
|
GO:0036211 |
438 |
0.771
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
124 |
0.769
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.766
|
Human Mouse |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.766
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
28 |
0.766
|
Human |
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.744
|
Human Mouse |
|
|
chromatin modification
|
GO:0016568 |
147 |
0.740
|
Mouse |
|
|
death
|
GO:0016265 |
284 |
0.736
|
|
|
|
organelle fission
|
GO:0048285 |
340 |
0.731
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.728
|
|
|
|
immune response
|
GO:0006955 |
246 |
0.726
|
Mouse |
|
|
autophagy
|
GO:0006914 |
108 |
0.713
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
213 |
0.705
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
18 |
0.700
|
Mouse |
|
|
proteolysis
|
GO:0006508 |
192 |
0.697
|
|
|
|
dna repair
|
GO:0006281 |
54 |
0.682
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
130 |
0.682
|
Human Mouse |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.668
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
89 |
0.666
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
24 |
0.657
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.653
|
Human Zebrafish Mouse |
|
|
telomere maintenance
|
GO:0000723 |
21 |
0.649
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
58 |
0.638
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
75 |
0.638
|
Human Mouse |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.634
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.626
|
Human Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
79 |
0.624
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.623
|
|
|
|
growth
|
GO:0040007 |
359 |
0.622
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
81 |
0.618
|
Human Mouse |
|
|
response to ionizing radiation
|
GO:0010212 |
32 |
0.617
|
|
|
|
cellular response to organic substance
|
GO:0071310 |
132 |
0.613
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
136 |
0.608
|
|
|
|
histone modification
|
GO:0016570 |
106 |
0.603
|
Mouse |
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.590
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.586
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.583
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.571
|
Human Mouse |
|
|
brain development
|
GO:0007420 |
120 |
0.562
|
Mouse |
|
|
dna integrity checkpoint
|
GO:0031570 |
81 |
0.557
|
Human Zebrafish Mouse |
|
|
cell death
|
GO:0008219 |
279 |
0.550
|
|
|
|
regulation of cell division
|
GO:0051302 |
72 |
0.547
|
Zebrafish Mouse |
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.544
|
|
|
|
dna conformation change
|
GO:0071103 |
105 |
0.543
|
Human |
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.542
|
|
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.541
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
16 |
0.539
|
Zebrafish Mouse |
|
|
regulation of neuron death
|
GO:1901214 |
26 |
0.536
|
Zebrafish Mouse |
|
|
taxis
|
GO:0042330 |
304 |
0.530
|
|
|
|
organelle localization
|
GO:0051640 |
148 |
0.526
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.524
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
83 |
0.519
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
39 |
0.515
|
|
|
|
response to uv
|
GO:0009411 |
24 |
0.511
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.505
|
|
|
|
gliogenesis
|
GO:0042063 |
80 |
0.503
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.500
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.497
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.493
|
Zebrafish Mouse |
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
77 |
0.491
|
|
|
|
chemotaxis
|
GO:0006935 |
249 |
0.488
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.487
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
97 |
0.474
|
Zebrafish |
|
|
apoptotic process
|
GO:0006915 |
159 |
0.473
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
38 |
0.467
|
Human Zebrafish Mouse |
|
|
regulation of chromosome organization
|
GO:0033044 |
64 |
0.465
|
Mouse |
|
|
chromatin silencing
|
GO:0006342 |
76 |
0.464
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.463
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.462
|
|
|
|
eggshell formation
|
GO:0030703 |
105 |
0.455
|
|
|
|
nuclear division
|
GO:0000280 |
332 |
0.454
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.453
|
Human Mouse |
|
|
homeostatic process
|
GO:0042592 |
199 |
0.449
|
Zebrafish Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.447
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.429
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.427
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.423
|
|
|
|
chorion containing eggshell formation
|
GO:0007304 |
105 |
0.423
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.422
|
Mouse |
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.413
|
Human Zebrafish Mouse |
|
|
developmental growth
|
GO:0048589 |
280 |
0.412
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
132 |
0.398
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.379
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
95 |
0.374
|
Human Zebrafish Mouse |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
26 |
0.373
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
57 |
0.372
|
Mouse |
|
|
compound eye development
|
GO:0048749 |
307 |
0.372
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
58 |
0.368
|
|
|
|
cell cycle arrest
|
GO:0007050 |
4 |
0.368
|
Human Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
87 |
0.366
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
25 |
0.363
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.363
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
27 |
0.356
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
15 |
0.353
|
|
|
|
regulation of response to extracellular stimulus
|
GO:0032104 |
18 |
0.349
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.346
|
Human Zebrafish Mouse |
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
5 |
0.345
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
13 |
0.341
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
78 |
0.331
|
Human Zebrafish Mouse |
|
|
regulation of mitosis
|
GO:0007088 |
56 |
0.327
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
4 |
0.326
|
Zebrafish |
|
|
spindle organization
|
GO:0007051 |
253 |
0.322
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.316
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
65 |
0.308
|
Human Mouse |
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.308
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.306
|
|
|
|
innate immune response
|
GO:0045087 |
144 |
0.305
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.305
|
Human Zebrafish Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
157 |
0.304
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
62 |
0.304
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
108 |
0.302
|
|
|
|
germ cell migration
|
GO:0008354 |
43 |
0.301
|
|
|
|
translation
|
GO:0006412 |
69 |
0.299
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.298
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
52 |
0.291
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
65 |
0.289
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
34 |
0.289
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.287
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
69 |
0.286
|
|
|
|
cell motility
|
GO:0048870 |
251 |
0.284
|
|
|
|
recombinational repair
|
GO:0000725 |
13 |
0.280
|
|
|
|
positive regulation of response to extracellular stimulus
|
GO:0032106 |
8 |
0.280
|
|
|
|
central nervous system development
|
GO:0007417 |
201 |
0.279
|
Zebrafish Mouse |
|
|
negative regulation of organelle organization
|
GO:0010639 |
56 |
0.273
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
78 |
0.272
|
|
|
|
regionalization
|
GO:0003002 |
416 |
0.268
|
Mouse |
|
|
cellular response to starvation
|
GO:0009267 |
61 |
0.266
|
|
|
|
cellular response to gamma radiation
|
GO:0071480 |
10 |
0.264
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
23 |
0.262
|
Human Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
35 |
0.260
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
29 |
0.252
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
42 |
0.249
|
|
|
|
response to oxidative stress
|
GO:0006979 |
86 |
0.249
|
Human Mouse Worm |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
54 |
0.246
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
66 |
0.243
|
|
|
|
protein catabolic process
|
GO:0030163 |
101 |
0.240
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
17 |
0.238
|
Zebrafish Mouse |
|
|
dendrite morphogenesis
|
GO:0048813 |
199 |
0.235
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
90 |
0.234
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.232
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.227
|
|
|
|
regulation of translation
|
GO:0006417 |
56 |
0.224
|
|
|
|
centrosome cycle
|
GO:0007098 |
137 |
0.223
|
|
|
|
eye development
|
GO:0001654 |
323 |
0.223
|
|
|
|
telomere capping
|
GO:0016233 |
11 |
0.223
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.220
|
|
|
|
defense response
|
GO:0006952 |
300 |
0.219
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
140 |
0.218
|
|
|
|
dorsal closure
|
GO:0007391 |
79 |
0.216
|
|
|
|
regulation of transport
|
GO:0051049 |
181 |
0.216
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
72 |
0.206
|
Human Mouse |
|
|
dendrite development
|
GO:0016358 |
204 |
0.206
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
108 |
0.204
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
69 |
0.198
|
|
|
|
locomotory behavior
|
GO:0007626 |
176 |
0.195
|
|
|
|
cell proliferation
|
GO:0008283 |
299 |
0.194
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.193
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.191
|
Mouse |
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.189
|
|
|
|
chromosome segregation
|
GO:0007059 |
157 |
0.186
|
Worm |
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.185
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
200 |
0.184
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
39 |
0.182
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.181
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.179
|
|
|
|
neuron projection guidance
|
GO:0097485 |
241 |
0.178
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
18 |
0.177
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.177
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
20 |
0.176
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.174
|
|
|
|
organ growth
|
GO:0035265 |
56 |
0.174
|
|
|
|
cellular response to radiation
|
GO:0071478 |
52 |
0.172
|
|
|
|
pigmentation
|
GO:0043473 |
75 |
0.171
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
87 |
0.171
|
Mouse |
|
|
positive regulation of response to nutrient levels
|
GO:0032109 |
8 |
0.167
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.167
|
Mouse |
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.165
|
Human |
|
|
dna recombination
|
GO:0006310 |
32 |
0.165
|
|
|
|
aging
|
GO:0007568 |
143 |
0.162
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
1 |
0.161
|
|
|
|
response to x ray
|
GO:0010165 |
8 |
0.161
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
7 |
0.158
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
106 |
0.158
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
151 |
0.158
|
|
|
|
localization of cell
|
GO:0051674 |
257 |
0.157
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
51 |
0.157
|
Mouse |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
13 |
0.156
|
Human Mouse |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
14 |
0.155
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
63 |
0.153
|
Human Mouse |
|
|
microtubule organizing center organization
|
GO:0031023 |
168 |
0.148
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
163 |
0.145
|
Mouse |
|
|
mitotic spindle organization
|
GO:0007052 |
220 |
0.144
|
|
|
|
regulation of cell growth
|
GO:0001558 |
43 |
0.144
|
Human |
|
|
stress activated mapk cascade
|
GO:0051403 |
52 |
0.142
|
Mouse |
|
|
developmental programmed cell death
|
GO:0010623 |
138 |
0.142
|
|
|
|
regulation of response to nutrient levels
|
GO:0032107 |
18 |
0.137
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
69 |
0.137
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.137
|
|
|
|
response to inorganic substance
|
GO:0010035 |
44 |
0.135
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
78 |
0.135
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.134
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
45 |
0.134
|
|
|
|
compound eye morphogenesis
|
GO:0001745 |
249 |
0.132
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
80 |
0.131
|
|
|
|
regulation of autophagy
|
GO:0010506 |
62 |
0.131
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
50 |
0.131
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
79 |
0.130
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.129
|
|
|
|
developmental pigmentation
|
GO:0048066 |
68 |
0.128
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
23 |
0.128
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
58 |
0.128
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.128
|
Mouse |
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
139 |
0.126
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
2 |
0.123
|
|
|
|
dna double strand break processing
|
GO:0000729 |
3 |
0.122
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
64 |
0.121
|
Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
71 |
0.120
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
4 |
0.119
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
10 |
0.119
|
Human Mouse |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
59 |
0.118
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
68 |
0.117
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.116
|
|
|
|
jnk cascade
|
GO:0007254 |
50 |
0.114
|
Mouse |
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.114
|
Mouse |
|
|
regulation of growth
|
GO:0040008 |
233 |
0.113
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
21 |
0.112
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.112
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
151 |
0.111
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
24 |
0.110
|
|
|
|
eggshell chorion assembly
|
GO:0007306 |
66 |
0.109
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
166 |
0.108
|
|
|
|
centrosome organization
|
GO:0051297 |
163 |
0.104
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.101
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
83 |
0.101
|
|
|
|
spermatogenesis
|
GO:0007283 |
200 |
0.100
|
Zebrafish |
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.099
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
1 |
0.098
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
170 |
0.098
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
6 |
0.098
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.096
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
179 |
0.095
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
16 |
0.094
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
79 |
0.094
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
36 |
0.094
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
108 |
0.094
|
|
|
|
neurological system process
|
GO:0050877 |
358 |
0.094
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.092
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.091
|
Zebrafish |
|
|
regulation of chromatin organization
|
GO:1902275 |
32 |
0.089
|
Mouse |
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.088
|
|
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.088
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
44 |
0.086
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.086
|
Mouse |
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.086
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.085
|
Human |
|
|
response to alkaloid
|
GO:0043279 |
26 |
0.085
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
47 |
0.084
|
|
|
|
rna splicing
|
GO:0008380 |
83 |
0.083
|
|
|
|
chromatin remodeling
|
GO:0006338 |
72 |
0.082
|
Mouse |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
13 |
0.081
|
Human Mouse |
|
|
oxoacid metabolic process
|
GO:0043436 |
103 |
0.081
|
|
|
|
camera type eye development
|
GO:0043010 |
4 |
0.080
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
42 |
0.080
|
Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.078
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
37 |
0.078
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
106 |
0.078
|
Mouse |
|
|
compound eye retinal cell programmed cell death
|
GO:0046667 |
23 |
0.078
|
|
|
|
single organism behavior
|
GO:0044708 |
391 |
0.078
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
1 |
0.078
|
Zebrafish Mouse |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.077
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
166 |
0.076
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
165 |
0.076
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.075
|
|
|
|
response to alcohol
|
GO:0097305 |
95 |
0.075
|
|
|
|
protein acetylation
|
GO:0006473 |
39 |
0.075
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
137 |
0.073
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
87 |
0.073
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.072
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
92 |
0.072
|
|
|
|
protein ubiquitination
|
GO:0016567 |
70 |
0.072
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
5 |
0.071
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
94 |
0.071
|
Mouse |
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
63 |
0.071
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.071
|
|
|
|
response to starvation
|
GO:0042594 |
97 |
0.071
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.071
|
Mouse |
|
|
regulation of jnk cascade
|
GO:0046328 |
40 |
0.071
|
Mouse |
|
|
double strand break repair via synthesis dependent strand annealing
|
GO:0045003 |
6 |
0.070
|
|
|
|
mitochondrion organization
|
GO:0007005 |
65 |
0.068
|
Human Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
145 |
0.068
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.068
|
|
|
|
reproductive system development
|
GO:0061458 |
74 |
0.067
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
80 |
0.067
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
58 |
0.066
|
Mouse |
|
|
sex differentiation
|
GO:0007548 |
81 |
0.066
|
Mouse |
|
|
phenol containing compound metabolic process
|
GO:0018958 |
57 |
0.065
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
44 |
0.065
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.065
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
116 |
0.064
|
Human Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.063
|
Mouse |
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.063
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.062
|
Human Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.062
|
Mouse |
|
|
regulation of response to external stimulus
|
GO:0032101 |
115 |
0.062
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
78 |
0.062
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.062
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
46 |
0.061
|
|
|
|
response to superoxide
|
GO:0000303 |
3 |
0.061
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
55 |
0.060
|
Mouse |
|
|
positive regulation of catabolic process
|
GO:0009896 |
105 |
0.060
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
108 |
0.060
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
112 |
0.060
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.060
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.060
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
31 |
0.060
|
Human Mouse |
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.059
|
|
|
|
positive regulation of execution phase of apoptosis
|
GO:1900119 |
4 |
0.059
|
|
|
|
cell division
|
GO:0051301 |
248 |
0.058
|
Zebrafish Mouse |
|
|
positive regulation of catalytic activity
|
GO:0043085 |
118 |
0.058
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
14 |
0.058
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.057
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
51 |
0.057
|
|
|
|
histolysis
|
GO:0007559 |
102 |
0.056
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
89 |
0.056
|
|
|
|
rna processing
|
GO:0006396 |
147 |
0.055
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
64 |
0.055
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
53 |
0.054
|
|
|
|
response to oxygen radical
|
GO:0000305 |
3 |
0.054
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
58 |
0.053
|
Human Zebrafish Worm |
|
|
regulation of hydrolase activity
|
GO:0051336 |
97 |
0.053
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.052
|
|
|
|
response to purine containing compound
|
GO:0014074 |
12 |
0.052
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
89 |
0.052
|
|
|
|
nuclear migration
|
GO:0007097 |
20 |
0.051
|
|
|
|
kidney development
|
GO:0001822 |
3 |
0.051
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
4 |
0.051
|
|
|
|
secretion
|
GO:0046903 |
109 |
0.051
|
Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
55 |
0.049
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
26 |
0.049
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
75 |
0.049
|
|
|
|
compound eye photoreceptor development
|
GO:0042051 |
78 |
0.049
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.049
|
|
|
|
regulation of cell size
|
GO:0008361 |
63 |
0.048
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
51 |
0.048
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
16 |
0.048
|
Mouse |
|
|
gonad development
|
GO:0008406 |
50 |
0.047
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
53 |
0.047
|
|
|
|
cell fate specification
|
GO:0001708 |
71 |
0.047
|
|
|
|
secretion by cell
|
GO:0032940 |
101 |
0.047
|
|
|
|
regulation of protein stability
|
GO:0031647 |
43 |
0.047
|
|
|
|
response to nutrient levels
|
GO:0031667 |
114 |
0.046
|
|
|
|
positive regulation of autophagy
|
GO:0010508 |
21 |
0.045
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
34 |
0.045
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
109 |
0.045
|
|
|
|
tube development
|
GO:0035295 |
244 |
0.044
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
127 |
0.044
|
Mouse |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.044
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
127 |
0.044
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
28 |
0.044
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.043
|
|
|
|
positive regulation of growth
|
GO:0045927 |
75 |
0.043
|
|
|
|
response to hypoxia
|
GO:0001666 |
53 |
0.043
|
Human Zebrafish Worm |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
17 |
0.043
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
98 |
0.043
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.043
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
174 |
0.043
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
63 |
0.042
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
24 |
0.042
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
64 |
0.042
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
70 |
0.042
|
|
|
|
glial cell migration
|
GO:0008347 |
31 |
0.042
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
18 |
0.042
|
Mouse |
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.042
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
28 |
0.041
|
|
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.041
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
168 |
0.041
|
|
|
|
regulation of protein transport
|
GO:0051223 |
57 |
0.040
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
17 |
0.040
|
|
|
|
chemical homeostasis
|
GO:0048878 |
92 |
0.039
|
Mouse |
|
|
rhythmic process
|
GO:0048511 |
106 |
0.039
|
|
|
|
multi organism behavior
|
GO:0051705 |
175 |
0.039
|
|
|
|
negative regulation of chromosome segregation
|
GO:0051985 |
14 |
0.039
|
|
|
|
respiratory system development
|
GO:0060541 |
213 |
0.039
|
|
|
|
dorsal appendage formation
|
GO:0046843 |
47 |
0.038
|
|
|
|
mitochondrial fusion
|
GO:0008053 |
7 |
0.038
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
78 |
0.037
|
|
|
|
response to drug
|
GO:0042493 |
17 |
0.037
|
Human Mouse |
|
|
compound eye photoreceptor cell differentiation
|
GO:0001751 |
140 |
0.037
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
46 |
0.037
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
116 |
0.037
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
19 |
0.037
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
45 |
0.037
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
4 |
0.036
|
|
|
|
dna replication
|
GO:0006260 |
48 |
0.036
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
29 |
0.036
|
Mouse |
|
|
germarium derived oocyte fate determination
|
GO:0007294 |
26 |
0.036
|
|
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
38 |
0.036
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
32 |
0.035
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
8 |
0.035
|
Human |
|
|
digestive system development
|
GO:0055123 |
149 |
0.035
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
41 |
0.035
|
Mouse |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
127 |
0.035
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
1 |
0.034
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
108 |
0.034
|
|
|
|
spermatid development
|
GO:0007286 |
98 |
0.034
|
|
|
|
response to gamma radiation
|
GO:0010332 |
17 |
0.033
|
|
|
|
response to bacterium
|
GO:0009617 |
198 |
0.033
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
119 |
0.033
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
103 |
0.033
|
|
|
|
telencephalon development
|
GO:0021537 |
2 |
0.032
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
8 |
0.032
|
Human Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
5 |
0.032
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
47 |
0.032
|
|
|
|
axis specification
|
GO:0009798 |
167 |
0.032
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
50 |
0.032
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
22 |
0.032
|
Human Mouse |
|
|
secondary metabolic process
|
GO:0019748 |
75 |
0.032
|
|
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
34 |
0.032
|
|
|
|
developmental maturation
|
GO:0021700 |
172 |
0.032
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
25 |
0.031
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
3 |
0.031
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
15 |
0.031
|
|
|
|
response to lipid
|
GO:0033993 |
38 |
0.031
|
|
|
|
cell adhesion
|
GO:0007155 |
136 |
0.031
|
|
|
|
response to hormone
|
GO:0009725 |
45 |
0.031
|
|
|
|
response to acid chemical
|
GO:0001101 |
25 |
0.030
|
|
|
|
response to other organism
|
GO:0051707 |
293 |
0.030
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
4 |
0.030
|
Mouse |
|
|
appendage development
|
GO:0048736 |
401 |
0.030
|
Mouse |
|
|
cellular macromolecule localization
|
GO:0070727 |
220 |
0.030
|
|
