Drosophila melanogaster

37 known processes

Miro (Dmel_CG5410)

Mitochondrial Rho

(Aliases: miro,CG5410,B682,dmiro,Dmel\CG5410,dMiro,DmMiro)

Miro biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron neuron synaptic transmission GO:0007270 14 0.858
chemical homeostasis GO:0048878 92 0.721
catabolic process GO:0009056 409 0.685
regulation of cellular component biogenesis GO:0044087 201 0.478
cell proliferation GO:0008283 299 0.476
proteolysis GO:0006508 192 0.458
regulation of protein metabolic process GO:0051246 256 0.449
response to abiotic stimulus GO:0009628 341 0.415
response to radiation GO:0009314 155 0.327
small molecule metabolic process GO:0044281 305 0.305
growth GO:0040007 359 0.299
regulation of multicellular organismal development GO:2000026 414 0.276
positive regulation of cellular component organization GO:0051130 156 0.276
protein modification by small protein conjugation or removal GO:0070647 106 0.270
establishment of localization in cell GO:0051649 402 0.267
positive regulation of biosynthetic process GO:0009891 316 0.250
regulation of organelle organization GO:0033043 196 0.234
synaptic transmission GO:0007268 288 0.229
epithelial cell migration GO:0010631 148 0.209
atp metabolic process GO:0046034 49 0.180
single organism behavior GO:0044708 391 0.180
regulation of cell development GO:0060284 215 0.173
protein localization GO:0008104 284 0.173
ribose phosphate metabolic process GO:0019693 145 0.171
neuroblast proliferation GO:0007405 74 0.167
mitochondrion organization GO:0007005 65 0.163
Human
regulation of cell differentiation GO:0045595 302 0.160
death GO:0016265 284 0.160
Human
eye development GO:0001654 323 0.158
regulation of synapse structure and activity GO:0050803 128 0.153
regulation of cell cycle GO:0051726 291 0.153
response to light stimulus GO:0009416 124 0.151
gliogenesis GO:0042063 80 0.150
regulation of molecular function GO:0065009 217 0.149
ribonucleotide metabolic process GO:0009259 145 0.141
regulation of localization GO:0032879 275 0.139
organelle localization GO:0051640 148 0.136
positive regulation of proteolysis GO:0045862 52 0.133
cellular catabolic process GO:0044248 372 0.130
regulation of catalytic activity GO:0050790 185 0.126
cell motility GO:0048870 251 0.124
cellular amine metabolic process GO:0044106 12 0.121
purine containing compound metabolic process GO:0072521 155 0.119
developmental programmed cell death GO:0010623 138 0.115
regulation of nervous system development GO:0051960 248 0.112
glycerophospholipid metabolic process GO:0006650 23 0.110
organic substance catabolic process GO:1901575 308 0.108
intracellular transport GO:0046907 228 0.107
Human
positive regulation of transport GO:0051050 92 0.105
epithelium migration GO:0090132 148 0.105
cell division GO:0051301 248 0.104
positive regulation of signaling GO:0023056 243 0.101
locomotory behavior GO:0007626 176 0.100
organonitrogen compound metabolic process GO:1901564 318 0.099
adult behavior GO:0030534 137 0.098
regulation of transport GO:0051049 181 0.097
positive regulation of cell communication GO:0010647 250 0.097
oxoacid metabolic process GO:0043436 103 0.097
cell death GO:0008219 279 0.094
Human
protein ubiquitination GO:0016567 70 0.094
regulation of cellular localization GO:0060341 136 0.093
phosphorylation GO:0016310 294 0.092
regulation of proteolysis GO:0030162 87 0.092
nucleoside phosphate metabolic process GO:0006753 162 0.091
regulation of neurogenesis GO:0050767 158 0.088
protein k48 linked ubiquitination GO:0070936 3 0.088
epithelial cell differentiation GO:0030855 322 0.087
single organism cellular localization GO:1902580 180 0.086
Human
protein modification by small protein conjugation GO:0032446 79 0.086
cellular macromolecule localization GO:0070727 220 0.085
positive regulation of organelle organization GO:0010638 65 0.084
regulation of cell cycle phase transition GO:1901987 130 0.083
protein maturation GO:0051604 71 0.080
cellular protein catabolic process GO:0044257 83 0.079
regionalization GO:0003002 416 0.078
regulation of cell morphogenesis GO:0022604 163 0.077
lipid localization GO:0010876 54 0.076
homeostatic process GO:0042592 199 0.075
Human
regulation of cell cycle process GO:0010564 181 0.074
ubiquitin dependent protein catabolic process GO:0006511 78 0.073
carboxylic acid metabolic process GO:0019752 92 0.072
positive regulation of developmental process GO:0051094 143 0.071
programmed cell death GO:0012501 257 0.071
Human
asymmetric cell division GO:0008356 37 0.069
regulation of cysteine type endopeptidase activity GO:2000116 27 0.066
organophosphate metabolic process GO:0019637 195 0.065
regulation of cell death GO:0010941 173 0.063
nucleotide metabolic process GO:0009117 161 0.063
lipid storage GO:0019915 38 0.063
regulation of peptidase activity GO:0052547 39 0.062
carbohydrate derivative metabolic process GO:1901135 217 0.062
single organism intracellular transport GO:1902582 207 0.062
Human
neurological system process GO:0050877 358 0.062
positive regulation of response to stimulus GO:0048584 323 0.061
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.061
regulation of anatomical structure size GO:0090066 163 0.059
immune system process GO:0002376 347 0.059
protein modification process GO:0036211 438 0.058
aromatic compound catabolic process GO:0019439 166 0.057
actin filament based process GO:0030029 220 0.057
modification dependent macromolecule catabolic process GO:0043632 79 0.056
maintenance of location GO:0051235 73 0.053
cell cycle phase transition GO:0044770 140 0.053
macromolecule catabolic process GO:0009057 161 0.052
negative regulation of catalytic activity GO:0043086 42 0.051
negative regulation of cell cycle process GO:0010948 109 0.050
regulation of secretion by cell GO:1903530 39 0.050
chaeta development GO:0022416 97 0.050
single organism membrane organization GO:0044802 93 0.049
Human
negative regulation of molecular function GO:0044092 51 0.049
central nervous system development GO:0007417 201 0.048
dendrite morphogenesis GO:0048813 199 0.048
protein complex assembly GO:0006461 200 0.047
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.047
regulation of cellular protein metabolic process GO:0032268 243 0.047
taxis GO:0042330 304 0.046
vesicle mediated transport GO:0016192 381 0.046
protein transport GO:0015031 155 0.046
establishment of mitochondrion localization GO:0051654 7 0.045
regulation of phosphate metabolic process GO:0019220 210 0.045
regulation of actin filament based process GO:0032970 42 0.045
nucleocytoplasmic transport GO:0006913 72 0.045
autophagy GO:0006914 108 0.045
membrane organization GO:0061024 112 0.044
Human
localization of cell GO:0051674 257 0.044
regulation of membrane potential GO:0042391 35 0.042
synaptic vesicle transport GO:0048489 50 0.042
purine ribonucleoside catabolic process GO:0046130 112 0.041
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.041
regulation of cellular amine metabolic process GO:0033238 3 0.040
response to alcohol GO:0097305 95 0.040
epidermis development GO:0008544 65 0.039
regulation of cellular component movement GO:0051270 42 0.039
negative regulation of programmed cell death GO:0043069 72 0.038
negative regulation of response to stimulus GO:0048585 258 0.038
protein catabolic process GO:0030163 101 0.038
circulatory system development GO:0072359 82 0.038
cell migration GO:0016477 238 0.037
cell fate determination GO:0001709 91 0.037
tube development GO:0035295 244 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.036
synaptic vesicle recycling GO:0036465 28 0.036
positive regulation of rna biosynthetic process GO:1902680 266 0.036
regulation of mitochondrial fission GO:0090140 7 0.036
proteasomal protein catabolic process GO:0010498 59 0.036
glycerolipid metabolic process GO:0046486 34 0.036
vesicle organization GO:0016050 44 0.035
cell cell junction assembly GO:0007043 38 0.035
dorsal ventral axis specification GO:0009950 66 0.035
defense response to bacterium GO:0042742 178 0.035
cellular protein localization GO:0034613 160 0.035
response to oxygen containing compound GO:1901700 200 0.034
purine containing compound catabolic process GO:0072523 112 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.034
regulation of dendrite morphogenesis GO:0048814 28 0.034
microtubule based transport GO:0010970 42 0.033
Human
regulation of neuron projection development GO:0010975 69 0.033
border follicle cell migration GO:0007298 113 0.033
positive regulation of signal transduction GO:0009967 223 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
dendrite development GO:0016358 204 0.033
regulation of necrotic cell death GO:0010939 1 0.033
nuclear division GO:0000280 332 0.032
hair cell differentiation GO:0035315 47 0.032
anterograde axon cargo transport GO:0008089 6 0.032
tissue migration GO:0090130 155 0.031
regulation of secretion GO:0051046 44 0.031
regulation of mitotic cell cycle phase transition GO:1901990 130 0.031
organic substance transport GO:0071702 257 0.031
regulation of lipid metabolic process GO:0019216 15 0.030
stem cell proliferation GO:0072089 88 0.030
ameboidal type cell migration GO:0001667 151 0.030
mitochondrion degradation GO:0000422 8 0.030
positive regulation of intracellular signal transduction GO:1902533 116 0.029
regulation of mitotic cell cycle GO:0007346 190 0.029
nucleobase containing compound catabolic process GO:0034655 165 0.029
energy taxis GO:0009453 21 0.029
actin cytoskeleton organization GO:0030036 206 0.029
protein targeting GO:0006605 64 0.029
purine ribonucleoside metabolic process GO:0046128 127 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.028
regulation of cell proliferation GO:0042127 163 0.028
protein complex biogenesis GO:0070271 201 0.028
organic acid metabolic process GO:0006082 103 0.028
positive regulation of catabolic process GO:0009896 105 0.028
ribonucleoside metabolic process GO:0009119 127 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
negative regulation of neuron death GO:1901215 18 0.027
negative regulation of cell cycle phase transition GO:1901988 103 0.027
developmental growth GO:0048589 280 0.026
apoptotic process GO:0006915 159 0.026
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
regulation of catabolic process GO:0009894 170 0.026
response to organic substance GO:0010033 284 0.026
regulation of programmed cell death GO:0043067 152 0.026
positive regulation of cell death GO:0010942 69 0.026
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.026
response to ethanol GO:0045471 59 0.026
cation homeostasis GO:0055080 51 0.026
regulation of immune system process GO:0002682 176 0.025
gland development GO:0048732 191 0.025
protein phosphorylation GO:0006468 169 0.025
single organism biosynthetic process GO:0044711 206 0.025
regulation of response to nutrient levels GO:0032107 18 0.025
organelle fission GO:0048285 340 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
establishment of protein localization GO:0045184 163 0.024
negative regulation of apoptotic process GO:0043066 63 0.024
developmental growth involved in morphogenesis GO:0060560 65 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
lipid metabolic process GO:0006629 121 0.024
regulation of vesicle mediated transport GO:0060627 59 0.024
nucleoside metabolic process GO:0009116 127 0.023
negative regulation of kinase activity GO:0033673 16 0.023
modification dependent protein catabolic process GO:0019941 78 0.023
negative regulation of signaling GO:0023057 219 0.023
regulation of protein ubiquitination GO:0031396 22 0.022
negative regulation of protein metabolic process GO:0051248 85 0.022
ion homeostasis GO:0050801 55 0.022
epithelial cell development GO:0002064 274 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
establishment of vesicle localization GO:0051650 51 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
regulation of neuron differentiation GO:0045664 103 0.022
cell fate specification GO:0001708 71 0.022
salivary gland development GO:0007431 162 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
adult locomotory behavior GO:0008344 76 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
regulation of multi organism process GO:0043900 131 0.021
negative regulation of developmental process GO:0051093 201 0.021
regulation of humoral immune response GO:0002920 51 0.021
sensory organ morphogenesis GO:0090596 260 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
cellular amide metabolic process GO:0043603 80 0.021
appendage morphogenesis GO:0035107 397 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
glial cell differentiation GO:0010001 35 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
mitochondrion distribution GO:0048311 10 0.020
cellular protein modification process GO:0006464 438 0.020
organophosphate catabolic process GO:0046434 112 0.020
protein localization to organelle GO:0033365 82 0.020
single organism catabolic process GO:0044712 228 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
macroautophagy GO:0016236 42 0.019
response to other organism GO:0051707 293 0.019
phospholipid metabolic process GO:0006644 23 0.019
molting cycle GO:0042303 56 0.019
g protein coupled receptor signaling pathway GO:0007186 136 0.019
nucleoside triphosphate catabolic process GO:0009143 108 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
dna replication GO:0006260 48 0.019
translation GO:0006412 69 0.018
lipid modification GO:0030258 24 0.018
salivary gland cell autophagic cell death GO:0035071 83 0.018
protein processing GO:0016485 68 0.018
organophosphate biosynthetic process GO:0090407 46 0.018
actin filament organization GO:0007015 126 0.018
dna metabolic process GO:0006259 227 0.018
regulation of neuron apoptotic process GO:0043523 16 0.017
positive regulation of dendrite morphogenesis GO:0050775 9 0.017
regulation of cell division GO:0051302 72 0.017
negative regulation of phosphorus metabolic process GO:0010563 45 0.017
secretion by cell GO:0032940 101 0.017
positive regulation of mitotic cell cycle GO:0045931 34 0.017
learning GO:0007612 75 0.017
golgi organization GO:0007030 66 0.017
forebrain development GO:0030900 2 0.017
phosphatidylinositol mediated signaling GO:0048015 4 0.017
regulation of actin filament bundle assembly GO:0032231 8 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
cellular response to nutrient levels GO:0031669 62 0.017
gland morphogenesis GO:0022612 145 0.016
regulation of synaptic transmission GO:0050804 69 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
cytoplasmic transport GO:0016482 130 0.016
mitochondrial fusion GO:0008053 7 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
peripheral nervous system development GO:0007422 52 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
positive regulation of secretion by cell GO:1903532 20 0.016
signal release GO:0023061 49 0.016
regulation of epithelial cell proliferation GO:0050678 4 0.016
purine nucleotide biosynthetic process GO:0006164 29 0.016
positive regulation of protein catabolic process GO:0045732 34 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.015
regulation of cellular protein catabolic process GO:1903362 44 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of phosphatase activity GO:0010921 3 0.015
ovarian follicle cell migration GO:0007297 121 0.015
response to external biotic stimulus GO:0043207 293 0.015
regulation of macroautophagy GO:0016241 15 0.015
salivary gland morphogenesis GO:0007435 145 0.015
macromolecular complex assembly GO:0065003 256 0.014
chromosome organization GO:0051276 360 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
intracellular signal transduction GO:0035556 300 0.014
negative regulation of signal transduction GO:0009968 206 0.014
reproductive system development GO:0061458 74 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
response to nutrient levels GO:0031667 114 0.014
inositol lipid mediated signaling GO:0048017 4 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
mitochondrial fission GO:0000266 8 0.014
neurotrophin signaling pathway GO:0038179 2 0.014
regulation of meiosis GO:0040020 3 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.014
regulation of protein catabolic process GO:0042176 55 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.013
positive regulation of endocytosis GO:0045807 22 0.013
retina development in camera type eye GO:0060041 4 0.013
negative regulation of growth GO:0045926 84 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
negative regulation of gene expression GO:0010629 387 0.013
regulation of protein complex assembly GO:0043254 42 0.013
regulation of apoptotic process GO:0042981 130 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
synaptic vesicle endocytosis GO:0048488 28 0.013
regulation of mitochondrial fusion GO:0010635 5 0.013
tube morphogenesis GO:0035239 191 0.013
cell type specific apoptotic process GO:0097285 38 0.013
necrotic cell death GO:0070265 1 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
actin polymerization or depolymerization GO:0008154 31 0.013
regulation of protein localization GO:0032880 76 0.013
regulation of hydrolase activity GO:0051336 97 0.013
nucleotide catabolic process GO:0009166 109 0.013
synaptic vesicle localization GO:0097479 53 0.012
segmentation GO:0035282 207 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
negative regulation of cell death GO:0060548 81 0.012
negative regulation of phosphate metabolic process GO:0045936 45 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
endomembrane system organization GO:0010256 119 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
neuroblast division GO:0055057 35 0.012
cell maturation GO:0048469 144 0.012
cellular protein complex assembly GO:0043623 71 0.012
epidermal cell differentiation GO:0009913 51 0.012
nuclear transport GO:0051169 72 0.012
cellular homeostasis GO:0019725 80 0.012
Human
regulation of developmental growth GO:0048638 174 0.012
cytoskeleton dependent intracellular transport GO:0030705 44 0.012
Human
glycosyl compound catabolic process GO:1901658 112 0.012
negative regulation of proteolysis GO:0045861 31 0.012
hemopoiesis GO:0030097 46 0.012
regulation of proteasomal protein catabolic process GO:0061136 39 0.011
regulation of nuclear division GO:0051783 58 0.011
amine metabolic process GO:0009308 12 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
erk1 and erk2 cascade GO:0070371 39 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
positive regulation of jun kinase activity GO:0043507 4 0.011
actin filament based movement GO:0030048 26 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
developmental maturation GO:0021700 172 0.011
brain development GO:0007420 120 0.011
positive regulation of molecular function GO:0044093 136 0.011
mitotic cell cycle embryonic GO:0045448 38 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
protein heterooligomerization GO:0051291 4 0.011
regulation of response to stress GO:0080134 200 0.011
regulation of growth GO:0040008 233 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
actin filament polymerization GO:0030041 27 0.010
actin mediated cell contraction GO:0070252 21 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
camera type eye development GO:0043010 4 0.010
regulation of endocytosis GO:0030100 37 0.010
glial cell development GO:0021782 27 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
histolysis GO:0007559 102 0.010
peptide metabolic process GO:0006518 80 0.010

Miro disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
synucleinopathy DOID:0050890 0 0.117
central nervous system disease DOID:331 0 0.117
disease of anatomical entity DOID:7 0 0.117
neurodegenerative disease DOID:1289 0 0.117
nervous system disease DOID:863 0 0.117
parkinson s disease DOID:14330 0 0.117
cancer DOID:162 0 0.042
disease of cellular proliferation DOID:14566 0 0.042
organ system cancer DOID:0050686 0 0.042
musculoskeletal system disease DOID:17 0 0.020