Drosophila melanogaster

79 known processes

Spindly (Dmel_CG15415)

CG15415 gene product from transcript CG15415-RB

(Aliases: CG15415,Dmel\CG15415)

Spindly biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle phase transition GO:1901987 130 0.328
organelle fission GO:0048285 340 0.166
negative regulation of mitotic cell cycle GO:0045930 109 0.147
regulation of cell cycle process GO:0010564 181 0.127
regulation of mitotic cell cycle GO:0007346 190 0.122
mitotic dna integrity checkpoint GO:0044774 75 0.117
mitotic nuclear division GO:0007067 213 0.102
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.101
negative regulation of cell cycle process GO:0010948 109 0.100
negative regulation of cellular metabolic process GO:0031324 382 0.098
cellular response to dna damage stimulus GO:0006974 223 0.097
cell cycle checkpoint GO:0000075 95 0.096
negative regulation of cell cycle GO:0045786 116 0.094
cell cycle phase transition GO:0044770 140 0.092
mitotic cell cycle checkpoint GO:0007093 88 0.090
imaginal disc derived appendage morphogenesis GO:0035114 395 0.090
negative regulation of biosynthetic process GO:0009890 277 0.088
chromosome segregation GO:0007059 157 0.085
dna damage checkpoint GO:0000077 78 0.077
dna integrity checkpoint GO:0031570 81 0.074
mitotic dna damage checkpoint GO:0044773 74 0.072
regulation of cell differentiation GO:0045595 302 0.069
regulation of cell cycle GO:0051726 291 0.069
cellular catabolic process GO:0044248 372 0.069
negative regulation of gene expression GO:0010629 387 0.067
regionalization GO:0003002 416 0.066
negative regulation of cell cycle phase transition GO:1901988 103 0.062
post embryonic appendage morphogenesis GO:0035120 385 0.060
appendage development GO:0048736 401 0.059
nuclear division GO:0000280 332 0.059
mitotic cell cycle phase transition GO:0044772 138 0.058
appendage morphogenesis GO:0035107 397 0.057
body morphogenesis GO:0010171 2 0.055
regulation of localization GO:0032879 275 0.055
imaginal disc derived appendage development GO:0048737 399 0.054
protein modification process GO:0036211 438 0.052
eye development GO:0001654 323 0.050
regulation of mitotic cell cycle phase transition GO:1901990 130 0.047
macromolecular complex assembly GO:0065003 256 0.047
response to abiotic stimulus GO:0009628 341 0.043
spindle organization GO:0007051 253 0.042
cellular protein modification process GO:0006464 438 0.041
organic substance catabolic process GO:1901575 308 0.040
establishment of localization in cell GO:0051649 402 0.039
negative regulation of cellular component organization GO:0051129 108 0.037
negative regulation of cellular biosynthetic process GO:0031327 277 0.036
mitotic g2 m transition checkpoint GO:0044818 70 0.035
endocytosis GO:0006897 310 0.034
mitotic sister chromatid segregation GO:0000070 87 0.034
negative regulation of nucleic acid templated transcription GO:1903507 240 0.033
chromosome organization GO:0051276 360 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.033
regulation of multicellular organismal development GO:2000026 414 0.033
g2 dna damage checkpoint GO:0031572 69 0.032
response to other organism GO:0051707 293 0.032
vesicle mediated transport GO:0016192 381 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.031
single organism catabolic process GO:0044712 228 0.031
protein dna complex subunit organization GO:0071824 86 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.031
regulation of nervous system development GO:0051960 248 0.031
death GO:0016265 284 0.031
dna metabolic process GO:0006259 227 0.031
mitotic g2 dna damage checkpoint GO:0007095 69 0.030
wing disc morphogenesis GO:0007472 344 0.030
negative regulation of transcription dna templated GO:0045892 237 0.030
single organism biosynthetic process GO:0044711 206 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.029
regulation of microtubule based process GO:0032886 49 0.028
negative regulation of organelle organization GO:0010639 56 0.028
regulation of programmed cell death GO:0043067 152 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
cell death GO:0008219 279 0.028
organic substance transport GO:0071702 257 0.026
response to biotic stimulus GO:0009607 294 0.026
endomembrane system organization GO:0010256 119 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
regulation of microtubule cytoskeleton organization GO:0070507 41 0.026
epithelial cell development GO:0002064 274 0.026
organonitrogen compound metabolic process GO:1901564 318 0.026
nucleobase containing compound catabolic process GO:0034655 165 0.025
tube development GO:0035295 244 0.025
catabolic process GO:0009056 409 0.025
response to radiation GO:0009314 155 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.024
response to external biotic stimulus GO:0043207 293 0.024
regulation of organelle organization GO:0033043 196 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.024
mitotic spindle organization GO:0007052 220 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
regulation of neurogenesis GO:0050767 158 0.024
dna replication GO:0006260 48 0.024
negative regulation of response to stimulus GO:0048585 258 0.023
cellular protein localization GO:0034613 160 0.023
female meiotic division GO:0007143 70 0.023
eye morphogenesis GO:0048592 260 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
dna conformation change GO:0071103 105 0.023
morphogenesis of an epithelium GO:0002009 276 0.023
aromatic compound catabolic process GO:0019439 166 0.022
negative regulation of molecular function GO:0044092 51 0.022
heterocycle catabolic process GO:0046700 166 0.022
response to organic substance GO:0010033 284 0.022
regulation of transport GO:0051049 181 0.022
regulation of gene silencing GO:0060968 63 0.022
actin cytoskeleton organization GO:0030036 206 0.022
intracellular signal transduction GO:0035556 300 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
gene silencing GO:0016458 138 0.021
compound eye development GO:0048749 307 0.021
response to light stimulus GO:0009416 124 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
organophosphate metabolic process GO:0019637 195 0.020
neuron projection guidance GO:0097485 241 0.020
programmed cell death GO:0012501 257 0.020
purine nucleotide metabolic process GO:0006163 146 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
microtubule organizing center organization GO:0031023 168 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
apoptotic process GO:0006915 159 0.019
positive regulation of response to stimulus GO:0048584 323 0.018
cellular ketone metabolic process GO:0042180 24 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
posttranscriptional gene silencing GO:0016441 46 0.018
organelle assembly GO:0070925 198 0.018
positive regulation of signaling GO:0023056 243 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
centrosome duplication GO:0051298 121 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
taxis GO:0042330 304 0.018
meiotic cell cycle GO:0051321 171 0.018
growth GO:0040007 359 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
negative regulation of cell communication GO:0010648 223 0.018
small molecule metabolic process GO:0044281 305 0.018
meiotic chromosome segregation GO:0045132 59 0.018
negative regulation of developmental process GO:0051093 201 0.017
phagocytosis GO:0006909 215 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
camera type eye development GO:0043010 4 0.017
telencephalon development GO:0021537 2 0.017
negative regulation of cell death GO:0060548 81 0.017
embryonic morphogenesis GO:0048598 206 0.017
cell proliferation GO:0008283 299 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
dna repair GO:0006281 54 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
adult behavior GO:0030534 137 0.016
g protein coupled receptor signaling pathway GO:0007186 136 0.016
protein localization to chromatin GO:0071168 3 0.016
protein dna complex assembly GO:0065004 63 0.016
forebrain development GO:0030900 2 0.016
meiotic cell cycle process GO:1903046 132 0.016
tube morphogenesis GO:0035239 191 0.016
negative regulation of programmed cell death GO:0043069 72 0.016
golgi organization GO:0007030 66 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
regulation of hydrolase activity GO:0051336 97 0.016
epithelial cell differentiation GO:0030855 322 0.016
microtubule polymerization or depolymerization GO:0031109 39 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
sister chromatid segregation GO:0000819 92 0.016
axon development GO:0061564 297 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
positive regulation of gene expression GO:0010628 290 0.015
centrosome cycle GO:0007098 137 0.015
proteolysis GO:0006508 192 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
cell adhesion GO:0007155 136 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
negative regulation of nervous system development GO:0051961 92 0.015
stem cell differentiation GO:0048863 117 0.015
cellular amine metabolic process GO:0044106 12 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
protein catabolic process GO:0030163 101 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
regulation of cellular catabolic process GO:0031329 157 0.014
nitrogen compound transport GO:0071705 85 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
chemotaxis GO:0006935 249 0.014
regulation of molecular function GO:0065009 217 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
organelle localization GO:0051640 148 0.014
ovarian follicle cell development GO:0030707 248 0.014
immune system process GO:0002376 347 0.014
response to oxygen containing compound GO:1901700 200 0.014
lateral inhibition GO:0046331 206 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
response to organophosphorus GO:0046683 2 0.014
neurological system process GO:0050877 358 0.014
peptidyl amino acid modification GO:0018193 105 0.014
spindle assembly GO:0051225 80 0.014
negative regulation of signal transduction GO:0009968 206 0.014
dna packaging GO:0006323 91 0.014
regulation of response to stress GO:0080134 200 0.014
regulation of catabolic process GO:0009894 170 0.014
establishment of organelle localization GO:0051656 122 0.014
regulation of growth GO:0040008 233 0.014
regulation of apoptotic process GO:0042981 130 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
defense response GO:0006952 300 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
phosphorylation GO:0016310 294 0.013
notch signaling pathway GO:0007219 120 0.013
purine containing compound catabolic process GO:0072523 112 0.013
circulatory system development GO:0072359 82 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
sensory organ morphogenesis GO:0090596 260 0.013
nucleotide metabolic process GO:0009117 161 0.013
ras protein signal transduction GO:0007265 88 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
purine containing compound metabolic process GO:0072521 155 0.012
digestive tract development GO:0048565 149 0.012
positive regulation of cell communication GO:0010647 250 0.012
negative regulation of neurogenesis GO:0050768 53 0.012
negative regulation of signaling GO:0023057 219 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
actin filament based process GO:0030029 220 0.012
embryonic organ development GO:0048568 50 0.012
regulation of cell death GO:0010941 173 0.012
organophosphate catabolic process GO:0046434 112 0.012
regulation of cell development GO:0060284 215 0.012
amine metabolic process GO:0009308 12 0.012
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
cell motility GO:0048870 251 0.012
negative regulation of catalytic activity GO:0043086 42 0.012
regulation of mitosis GO:0007088 56 0.012
response to bacterium GO:0009617 198 0.012
regulation of catalytic activity GO:0050790 185 0.012
negative regulation of cell division GO:0051782 17 0.012
cytoplasmic transport GO:0016482 130 0.012
intracellular transport GO:0046907 228 0.011
axon guidance GO:0007411 233 0.011
negative regulation of microtubule depolymerization GO:0007026 21 0.011
leg disc morphogenesis GO:0007478 80 0.011
embryonic pattern specification GO:0009880 174 0.011
hindbrain development GO:0030902 2 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
positive regulation of signal transduction GO:0009967 223 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
heart development GO:0007507 82 0.011
spermatogenesis GO:0007283 200 0.011
regulation of developmental growth GO:0048638 174 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
positive regulation of cell development GO:0010720 61 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
intracellular protein transport GO:0006886 104 0.011
nucleoside catabolic process GO:0009164 112 0.011
protein transport GO:0015031 155 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
biological adhesion GO:0022610 138 0.011
tissue morphogenesis GO:0048729 297 0.011
chromosome separation GO:0051304 42 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.010
aging GO:0007568 143 0.010
chaeta development GO:0022416 97 0.010
multicellular organismal reproductive behavior GO:0033057 110 0.010
positive regulation of developmental process GO:0051094 143 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
axis specification GO:0009798 167 0.010
mitotic sister chromatid separation GO:0051306 30 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
connective tissue development GO:0061448 3 0.010
defense response to other organism GO:0098542 225 0.010
chromatin silencing GO:0006342 76 0.010
mrna processing GO:0006397 104 0.010
protein phosphorylation GO:0006468 169 0.010

Spindly disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.019