Drosophila melanogaster

51 known processes

dp (Dmel_CG33196)

dumpy

(Aliases: CG15637,CR33195,l(2)24Fd,Dmel\CG33196,CG31724,CG31725,CG31726,CG31727,DP,CG33000,CG33086,olv[D],SP460,CG31968,CG31966,BcDNA:SD02173,CG31964,CG31965,Dp,CT35799,CG33196,Mur24F,CG31967)

dp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eggshell chorion assembly GO:0007306 66 0.916
cell motility GO:0048870 251 0.744
epithelial cell migration GO:0010631 148 0.642
tissue migration GO:0090130 155 0.528
negative regulation of cell communication GO:0010648 223 0.468
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.445
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.440
chromosome organization GO:0051276 360 0.430
epithelium migration GO:0090132 148 0.356
oocyte development GO:0048599 124 0.352
anatomical structure homeostasis GO:0060249 97 0.324
oocyte microtubule cytoskeleton organization GO:0016325 35 0.309
oocyte differentiation GO:0009994 145 0.299
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.291
cell migration GO:0016477 238 0.284
transcription from rna polymerase ii promoter GO:0006366 368 0.272
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.270
establishment or maintenance of cell polarity GO:0007163 167 0.268
regulation of proteasomal protein catabolic process GO:0061136 39 0.266
circadian rhythm GO:0007623 105 0.236
dorsal appendage formation GO:0046843 47 0.232
germarium derived egg chamber formation GO:0007293 101 0.232
cell division GO:0051301 248 0.224
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.224
cuticle development GO:0042335 86 0.212
ameboidal type cell migration GO:0001667 151 0.188
ovarian follicle cell migration GO:0007297 121 0.188
morphogenesis of an epithelium GO:0002009 276 0.184
ovarian follicle cell development GO:0030707 248 0.176
cellular protein modification process GO:0006464 438 0.170
molting cycle GO:0042303 56 0.161
actin filament organization GO:0007015 126 0.159
segmentation GO:0035282 207 0.155
mapk cascade GO:0000165 107 0.145
regulation of cellular component biogenesis GO:0044087 201 0.145
regulation of multicellular organismal development GO:2000026 414 0.144
anterior posterior pattern specification GO:0009952 136 0.142
positive regulation of rna metabolic process GO:0051254 271 0.136
columnar cuboidal epithelial cell development GO:0002066 249 0.133
post embryonic appendage morphogenesis GO:0035120 385 0.131
morphogenesis of a branching epithelium GO:0061138 45 0.129
positive regulation of transcription dna templated GO:0045893 266 0.128
modification dependent protein catabolic process GO:0019941 78 0.125
sex differentiation GO:0007548 81 0.122
open tracheal system development GO:0007424 204 0.120
positive regulation of biosynthetic process GO:0009891 316 0.117
oocyte construction GO:0007308 112 0.111
wnt signaling pathway GO:0016055 98 0.103
cell maturation GO:0048469 144 0.099
branching morphogenesis of an epithelial tube GO:0048754 45 0.099
cell proliferation GO:0008283 299 0.094
reproductive structure development GO:0048608 74 0.094
positive regulation of gene expression GO:0010628 290 0.093
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.088
positive regulation of nucleic acid templated transcription GO:1903508 266 0.082
axon guidance GO:0007411 233 0.082
negative regulation of cell cycle GO:0045786 116 0.080
ubiquitin dependent protein catabolic process GO:0006511 78 0.079
eye development GO:0001654 323 0.071
developmental maturation GO:0021700 172 0.070
negative regulation of cell differentiation GO:0045596 143 0.069
pole plasm mrna localization GO:0019094 49 0.068
chromosome segregation GO:0007059 157 0.063
oocyte axis specification GO:0007309 108 0.063
cellular protein localization GO:0034613 160 0.062
regulation of anatomical structure size GO:0090066 163 0.062
negative regulation of signaling GO:0023057 219 0.061
organ growth GO:0035265 56 0.060
epithelial cell differentiation GO:0030855 322 0.058
negative regulation of signal transduction GO:0009968 206 0.058
tissue morphogenesis GO:0048729 297 0.057
positive regulation of cellular biosynthetic process GO:0031328 316 0.057
regulation of phosphatase activity GO:0010921 3 0.056
determination of adult lifespan GO:0008340 137 0.056
regulation of imaginal disc derived wing size GO:0044719 20 0.055
negative regulation of gene expression GO:0010629 387 0.055
gonad development GO:0008406 50 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.055
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.053
embryonic pattern specification GO:0009880 174 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
positive regulation of rna biosynthetic process GO:1902680 266 0.051
protein complex assembly GO:0006461 200 0.049
chemosensory behavior GO:0007635 106 0.049
appendage morphogenesis GO:0035107 397 0.048
border follicle cell migration GO:0007298 113 0.048
programmed cell death GO:0012501 257 0.048
negative regulation of cardioblast differentiation GO:0051892 7 0.045
defense response GO:0006952 300 0.045
response to extracellular stimulus GO:0009991 116 0.044
neuron projection guidance GO:0097485 241 0.043
localization of cell GO:0051674 257 0.043
regulation of nervous system development GO:0051960 248 0.041
cellular macromolecule catabolic process GO:0044265 136 0.040
regulation of cell cycle process GO:0010564 181 0.040
branching involved in open tracheal system development GO:0060446 45 0.040
morphogenesis of follicular epithelium GO:0016333 36 0.039
response to bacterium GO:0009617 198 0.038
embryo development ending in birth or egg hatching GO:0009792 152 0.038
meiotic cell cycle GO:0051321 171 0.037
response to nutrient levels GO:0031667 114 0.036
nuclear division GO:0000280 332 0.036
wound healing GO:0042060 75 0.036
morphogenesis of a branching structure GO:0001763 45 0.035
cellular protein complex assembly GO:0043623 71 0.035
proteolysis GO:0006508 192 0.035
genitalia development GO:0048806 26 0.035
meiotic cell cycle process GO:1903046 132 0.035
epithelial cell migration open tracheal system GO:0007427 32 0.034
specification of organ identity GO:0010092 3 0.034
oocyte dorsal ventral axis specification GO:0007310 34 0.034
protein modification process GO:0036211 438 0.034
cellular protein catabolic process GO:0044257 83 0.033
regulation of cell division GO:0051302 72 0.033
regulation of reproductive process GO:2000241 54 0.032
homeostatic process GO:0042592 199 0.032
molting cycle chitin based cuticle GO:0007591 56 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.031
catabolic process GO:0009056 409 0.030
cellular component assembly involved in morphogenesis GO:0010927 151 0.030
regulation of programmed cell death GO:0043067 152 0.029
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.029
protein modification by small protein conjugation GO:0032446 79 0.029
regulation of cell differentiation GO:0045595 302 0.029
positive regulation of developmental growth GO:0048639 62 0.029
regulation of apoptotic process GO:0042981 130 0.029
developmental growth GO:0048589 280 0.028
regulation of wnt signaling pathway GO:0030111 68 0.028
single organism cellular localization GO:1902580 180 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.027
respiratory system development GO:0060541 213 0.026
cellular response to chemical stimulus GO:0070887 199 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
nuclear import GO:0051170 51 0.025
eggshell formation GO:0030703 105 0.025
developmental programmed cell death GO:0010623 138 0.025
mitotic nuclear division GO:0007067 213 0.025
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.024
dorsal ventral pattern formation GO:0009953 133 0.024
nephron development GO:0072006 3 0.024
regulation of cell development GO:0060284 215 0.024
regionalization GO:0003002 416 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
regulation of cell cycle GO:0051726 291 0.024
apoptotic signaling pathway GO:0097190 27 0.024
protein complex biogenesis GO:0070271 201 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
wing disc morphogenesis GO:0007472 344 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
protein modification by small protein conjugation or removal GO:0070647 106 0.022
organelle fission GO:0048285 340 0.022
cellular macromolecular complex assembly GO:0034622 153 0.022
nucleocytoplasmic transport GO:0006913 72 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
melanin metabolic process GO:0006582 47 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
developmental growth involved in morphogenesis GO:0060560 65 0.021
regulation of mapk cascade GO:0043408 92 0.021
synapse organization GO:0050808 196 0.020
connective tissue development GO:0061448 3 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
cellular response to endogenous stimulus GO:0071495 80 0.020
oocyte anterior posterior axis specification GO:0007314 72 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
reproductive system development GO:0061458 74 0.019
macromolecular complex assembly GO:0065003 256 0.019
maternal determination of anterior posterior axis embryo GO:0008358 74 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.019
regulation of actin cytoskeleton organization GO:0032956 42 0.019
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.019
canonical wnt signaling pathway GO:0060070 21 0.019
phagocytosis GO:0006909 215 0.019
stem cell development GO:0048864 79 0.018
protein localization GO:0008104 284 0.018
nephron epithelium morphogenesis GO:0072088 3 0.018
response to other organism GO:0051707 293 0.018
macromolecule catabolic process GO:0009057 161 0.018
dna metabolic process GO:0006259 227 0.018
regulation of apoptotic signaling pathway GO:2001233 10 0.018
stem cell maintenance GO:0019827 67 0.018
epithelial cell development GO:0002064 274 0.017
negative regulation of transcription factor import into nucleus GO:0042992 4 0.017
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
phosphorylation GO:0016310 294 0.016
defense response to fungus GO:0050832 48 0.016
regulation of cellular protein catabolic process GO:1903362 44 0.016
protein ubiquitination GO:0016567 70 0.016
cellular response to decreased oxygen levels GO:0036294 30 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
vesicle mediated transport GO:0016192 381 0.016
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.016
axis specification GO:0009798 167 0.016
regulation of myotube differentiation GO:0010830 6 0.015
cellular catabolic process GO:0044248 372 0.015
innate immune response GO:0045087 144 0.015
neuron recognition GO:0008038 101 0.015
cell death GO:0008219 279 0.015
response to external biotic stimulus GO:0043207 293 0.015
imaginal disc derived leg segmentation GO:0036011 26 0.015
regulation of cellular catabolic process GO:0031329 157 0.014
single organism cell adhesion GO:0098602 47 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
defense response to bacterium GO:0042742 178 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
hindbrain development GO:0030902 2 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 6 0.014
neural precursor cell proliferation GO:0061351 75 0.014
cell recognition GO:0008037 102 0.014
regulation of circadian rhythm GO:0042752 49 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.014
axonogenesis GO:0007409 290 0.013
chorion containing eggshell formation GO:0007304 105 0.013
muscle tissue morphogenesis GO:0060415 2 0.013
regulation of cell cycle checkpoint GO:1901976 2 0.013
multi organism behavior GO:0051705 175 0.013
organic substance catabolic process GO:1901575 308 0.013
organic acid metabolic process GO:0006082 103 0.013
protein localization to organelle GO:0033365 82 0.013
regulation of cell death GO:0010941 173 0.012
biological adhesion GO:0022610 138 0.012
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.012
membrane organization GO:0061024 112 0.012
chromatin organization GO:0006325 207 0.012
meiotic chromosome movement towards spindle pole GO:0016344 1 0.012
intracellular protein transport GO:0006886 104 0.012
regulation of proteolysis GO:0030162 87 0.012
compound eye development GO:0048749 307 0.012
anterior posterior axis specification GO:0009948 109 0.012
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
cell cycle arrest GO:0007050 4 0.011
generation of precursor metabolites and energy GO:0006091 42 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.011
notch signaling pathway GO:0007219 120 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
regulation of organ growth GO:0046620 42 0.011
positive regulation of protein modification process GO:0031401 58 0.011
negative regulation of nucleotide metabolic process GO:0045980 4 0.011
protein catabolic process GO:0030163 101 0.011
stress granule disassembly GO:0035617 1 0.011
tube development GO:0035295 244 0.011
cellular response to external stimulus GO:0071496 66 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
regulation of developmental growth GO:0048638 174 0.011
mesenchymal cell development GO:0014031 1 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
tube morphogenesis GO:0035239 191 0.010
stem cell differentiation GO:0048863 117 0.010
positive regulation of binding GO:0051099 4 0.010
response to nitrogen compound GO:1901698 90 0.010
negative regulation of notch signaling pathway GO:0045746 41 0.010
jnk cascade GO:0007254 50 0.010
organonitrogen compound metabolic process GO:1901564 318 0.010
cell cycle phase transition GO:0044770 140 0.010
cellular macromolecule localization GO:0070727 220 0.010

dp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.016
syndrome DOID:225 0 0.011