Drosophila melanogaster

111 known processes

Ube3a (Dmel_CG6190)

Ubiquitin protein ligase E3A

(Aliases: Dmel\CG6190,dUBE3A,UBE3A,As,dube3a,AS,CG6190,das,Dube3a,dube3A)

Ube3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification process GO:0036211 438 0.836
cellular protein modification process GO:0006464 438 0.803
protein modification by small protein conjugation or removal GO:0070647 106 0.639
positive regulation of response to stimulus GO:0048584 323 0.473
Mouse
cellular protein catabolic process GO:0044257 83 0.442
regulation of protein metabolic process GO:0051246 256 0.417
protein ubiquitination GO:0016567 70 0.357
apoptotic process GO:0006915 159 0.325
chemosensory behavior GO:0007635 106 0.300
negative regulation of cell death GO:0060548 81 0.269
regulation of anatomical structure morphogenesis GO:0022603 242 0.264
transcription from rna polymerase ii promoter GO:0006366 368 0.257
Mouse
negative regulation of gene expression GO:0010629 387 0.249
carbohydrate derivative metabolic process GO:1901135 217 0.245
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.241
sensory organ morphogenesis GO:0090596 260 0.234
regulation of cellular ketone metabolic process GO:0010565 3 0.211
regulation of programmed cell death GO:0043067 152 0.210
protein localization GO:0008104 284 0.205
regulation of cellular protein metabolic process GO:0032268 243 0.199
small molecule metabolic process GO:0044281 305 0.198
appendage morphogenesis GO:0035107 397 0.196
response to light stimulus GO:0009416 124 0.187
response to radiation GO:0009314 155 0.185
circadian rhythm GO:0007623 105 0.179
learning or memory GO:0007611 141 0.175
protein modification by small protein conjugation GO:0032446 79 0.174
fertilization GO:0009566 26 0.171
Mouse
appendage development GO:0048736 401 0.171
posttranscriptional regulation of gene expression GO:0010608 145 0.171
neurological system process GO:0050877 358 0.167
morphogenesis of an epithelium GO:0002009 276 0.158
positive regulation of macromolecule metabolic process GO:0010604 405 0.158
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.147
response to abiotic stimulus GO:0009628 341 0.145
long term memory GO:0007616 62 0.141
positive regulation of protein metabolic process GO:0051247 128 0.139
positive regulation of cell communication GO:0010647 250 0.139
Mouse
organic substance transport GO:0071702 257 0.135
cell death GO:0008219 279 0.130
modification dependent macromolecule catabolic process GO:0043632 79 0.129
protein transport GO:0015031 155 0.128
intracellular transport GO:0046907 228 0.128
negative regulation of cellular metabolic process GO:0031324 382 0.128
glycosyl compound metabolic process GO:1901657 127 0.127
negative regulation of apoptotic process GO:0043066 63 0.127
negative regulation of signal transduction GO:0009968 206 0.127
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.124
Mouse
ribonucleotide catabolic process GO:0009261 109 0.122
positive regulation of nucleic acid templated transcription GO:1903508 266 0.121
Mouse
gravitaxis GO:0042332 26 0.118
eye morphogenesis GO:0048592 260 0.112
detection of stimulus GO:0051606 156 0.112
central nervous system development GO:0007417 201 0.109
ribonucleoside metabolic process GO:0009119 127 0.108
oxoacid metabolic process GO:0043436 103 0.107
notch signaling pathway GO:0007219 120 0.106
organophosphate catabolic process GO:0046434 112 0.104
organophosphate metabolic process GO:0019637 195 0.104
negative regulation of neuron apoptotic process GO:0043524 14 0.102
eye development GO:0001654 323 0.101
purine containing compound metabolic process GO:0072521 155 0.101
wing disc morphogenesis GO:0007472 344 0.101
ubiquitin dependent protein catabolic process GO:0006511 78 0.099
programmed cell death GO:0012501 257 0.099
organic acid metabolic process GO:0006082 103 0.098
organonitrogen compound metabolic process GO:1901564 318 0.098
establishment of localization in cell GO:0051649 402 0.095
regulation of cell death GO:0010941 173 0.093
post embryonic appendage morphogenesis GO:0035120 385 0.090
cell proliferation GO:0008283 299 0.088
single organism intracellular transport GO:1902582 207 0.088
centrosome duplication GO:0051298 121 0.087
protein complex assembly GO:0006461 200 0.086
regulation of intracellular signal transduction GO:1902531 236 0.084
Mouse
photoreceptor cell differentiation GO:0046530 170 0.084
protein deubiquitination GO:0016579 17 0.083
negative regulation of molecular function GO:0044092 51 0.083
olfactory learning GO:0008355 56 0.082
negative regulation of programmed cell death GO:0043069 72 0.081
carboxylic acid metabolic process GO:0019752 92 0.080
purine nucleoside catabolic process GO:0006152 112 0.079
dendrite morphogenesis GO:0048813 199 0.077
tissue morphogenesis GO:0048729 297 0.077
positive regulation of biosynthetic process GO:0009891 316 0.076
Mouse
microtubule organizing center organization GO:0031023 168 0.076
purine ribonucleotide metabolic process GO:0009150 145 0.074
sperm mitochondrion organization GO:0030382 7 0.074
nucleus organization GO:0006997 45 0.073
regulation of cellular localization GO:0060341 136 0.073
cellular macromolecule localization GO:0070727 220 0.072
purine nucleoside metabolic process GO:0042278 127 0.072
compound eye development GO:0048749 307 0.072
organic substance catabolic process GO:1901575 308 0.070
nucleoside triphosphate catabolic process GO:0009143 108 0.070
ribose phosphate metabolic process GO:0019693 145 0.069
nucleoside metabolic process GO:0009116 127 0.068
atp metabolic process GO:0046034 49 0.067
positive regulation of signal transduction GO:0009967 223 0.064
Mouse
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.064
negative regulation of cellular protein metabolic process GO:0032269 85 0.063
gene silencing by mirna GO:0035195 22 0.063
cellular nitrogen compound catabolic process GO:0044270 165 0.063
organelle fission GO:0048285 340 0.063
regulation of protein modification process GO:0031399 112 0.062
locomotory behavior GO:0007626 176 0.062
phosphorylation GO:0016310 294 0.060
chromosome organization GO:0051276 360 0.060
spermatogenesis GO:0007283 200 0.059
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.059
regulation of mitochondrial fusion GO:0010635 5 0.059
purine ribonucleoside metabolic process GO:0046128 127 0.059
locomotor rhythm GO:0045475 56 0.057
catabolic process GO:0009056 409 0.057
ribonucleoside triphosphate catabolic process GO:0009203 108 0.057
regulation of localization GO:0032879 275 0.057
intracellular protein transport GO:0006886 104 0.056
nucleoside triphosphate metabolic process GO:0009141 120 0.056
regulation of protein catabolic process GO:0042176 55 0.055
positive regulation of phosphate metabolic process GO:0045937 139 0.055
cellular response to dna damage stimulus GO:0006974 223 0.055
ventral furrow formation GO:0007370 17 0.054
regulation of apoptotic process GO:0042981 130 0.054
protein phosphorylation GO:0006468 169 0.054
tube development GO:0035295 244 0.053
imaginal disc derived appendage development GO:0048737 399 0.053
autophagy GO:0006914 108 0.052
nucleotide catabolic process GO:0009166 109 0.051
brain development GO:0007420 120 0.051
positive regulation of gene expression GO:0010628 290 0.051
Mouse
mesenchymal cell differentiation GO:0048762 1 0.050
protein localization to organelle GO:0033365 82 0.050
establishment of protein localization GO:0045184 163 0.050
single organism behavior GO:0044708 391 0.050
gene silencing GO:0016458 138 0.050
negative regulation of response to stimulus GO:0048585 258 0.049
taxis GO:0042330 304 0.049
nucleobase containing compound catabolic process GO:0034655 165 0.049
cellular amino acid metabolic process GO:0006520 61 0.049
aromatic compound catabolic process GO:0019439 166 0.049
amine metabolic process GO:0009308 12 0.049
regulation of endocytosis GO:0030100 37 0.049
proteasomal protein catabolic process GO:0010498 59 0.047
nucleoside phosphate metabolic process GO:0006753 162 0.047
regulation of nervous system development GO:0051960 248 0.046
purine ribonucleoside catabolic process GO:0046130 112 0.046
ribonucleoside triphosphate metabolic process GO:0009199 119 0.046
enzyme linked receptor protein signaling pathway GO:0007167 179 0.046
secretion GO:0046903 109 0.046
positive regulation of rna metabolic process GO:0051254 271 0.045
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.045
regulation of catabolic process GO:0009894 170 0.045
positive regulation of signaling GO:0023056 243 0.045
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.044
compound eye morphogenesis GO:0001745 249 0.044
olfactory behavior GO:0042048 97 0.044
nuclear import GO:0051170 51 0.043
phagocytosis GO:0006909 215 0.043
circadian behavior GO:0048512 76 0.043
imaginal disc derived appendage morphogenesis GO:0035114 395 0.043
head development GO:0060322 135 0.042
protein modification by small protein removal GO:0070646 28 0.041
regulation of catalytic activity GO:0050790 185 0.041
negative regulation of neuron death GO:1901215 18 0.041
regulation of receptor mediated endocytosis GO:0048259 9 0.040
positive regulation of rna biosynthetic process GO:1902680 266 0.040
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.040
regulation of notch signaling pathway GO:0008593 100 0.040
female meiotic division GO:0007143 70 0.040
regulation of cellular amine metabolic process GO:0033238 3 0.040
regulation of molecular function GO:0065009 217 0.039
cognition GO:0050890 141 0.039
purine ribonucleotide catabolic process GO:0009154 109 0.039
regulation of gene expression epigenetic GO:0040029 128 0.038
death GO:0016265 284 0.038
cellularization GO:0007349 90 0.038
vesicle mediated transport GO:0016192 381 0.038
Mouse
regulation of protein stability GO:0031647 43 0.038
purine containing compound catabolic process GO:0072523 112 0.037
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.037
response to external biotic stimulus GO:0043207 293 0.037
regulation of erbb signaling pathway GO:1901184 42 0.037
membrane budding GO:0006900 4 0.037
nucleotide metabolic process GO:0009117 161 0.037
endocytosis GO:0006897 310 0.037
Mouse
histolysis GO:0007559 102 0.037
glycoprotein metabolic process GO:0009100 41 0.036
regulation of protein phosphorylation GO:0001932 64 0.036
positive regulation of phosphorylation GO:0042327 87 0.036
posttranscriptional gene silencing GO:0016441 46 0.035
gastrulation with mouth forming first GO:0001703 36 0.035
dna metabolic process GO:0006259 227 0.035
signal transduction by phosphorylation GO:0023014 107 0.035
cell type specific apoptotic process GO:0097285 38 0.035
nuclear transport GO:0051169 72 0.034
protein import GO:0017038 55 0.034
establishment of protein localization to organelle GO:0072594 62 0.034
neuron apoptotic process GO:0051402 17 0.033
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
protein catabolic process GO:0030163 101 0.033
membrane organization GO:0061024 112 0.032
response to alcohol GO:0097305 95 0.032
cellular macromolecule catabolic process GO:0044265 136 0.032
ribonucleotide metabolic process GO:0009259 145 0.032
regulation of transport GO:0051049 181 0.032
nucleoside monophosphate metabolic process GO:0009123 52 0.032
heterocycle catabolic process GO:0046700 166 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
chromatin modification GO:0016568 147 0.032
purine nucleoside triphosphate metabolic process GO:0009144 119 0.031
organonitrogen compound catabolic process GO:1901565 128 0.031
defense response to virus GO:0051607 23 0.031
regulation of cellular catabolic process GO:0031329 157 0.031
mapk cascade GO:0000165 107 0.031
mitochondrion organization GO:0007005 65 0.030
translation GO:0006412 69 0.030
regulation of phosphorylation GO:0042325 147 0.030
molting cycle GO:0042303 56 0.030
single organism nuclear import GO:1902593 51 0.030
cellular protein localization GO:0034613 160 0.030
single organism cellular localization GO:1902580 180 0.030
nucleoside phosphate catabolic process GO:1901292 110 0.030
modification dependent protein catabolic process GO:0019941 78 0.030
regulation of phosphorus metabolic process GO:0051174 210 0.030
protein targeting GO:0006605 64 0.029
response to virus GO:0009615 28 0.029
germarium derived female germ line cyst formation GO:0030727 42 0.029
single organism catabolic process GO:0044712 228 0.029
regulation of protein import into nucleus GO:0042306 28 0.029
multicellular organism growth GO:0035264 46 0.029
compound eye photoreceptor cell differentiation GO:0001751 140 0.029
cellular amine metabolic process GO:0044106 12 0.028
telomere organization GO:0032200 21 0.028
posttranscriptional gene silencing by rna GO:0035194 45 0.028
regulation of establishment of protein localization GO:0070201 61 0.028
glycosyl compound catabolic process GO:1901658 112 0.028
mitotic cytokinesis GO:0000281 50 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.028
negative regulation of response to oxidative stress GO:1902883 1 0.028
epidermal growth factor receptor signaling pathway GO:0007173 58 0.027
negative regulation of cellular biosynthetic process GO:0031327 277 0.027
mesenchymal cell development GO:0014031 1 0.027
negative regulation of signaling GO:0023057 219 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.027
protein localization to nucleus GO:0034504 55 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.026
tube morphogenesis GO:0035239 191 0.026
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.026
serotonin metabolic process GO:0042428 2 0.026
cellular protein complex assembly GO:0043623 71 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
response to gravity GO:0009629 26 0.025
sensory perception GO:0007600 196 0.025
regulation of mitochondrial fission GO:0090140 7 0.025
telomere maintenance GO:0000723 21 0.025
macromolecule catabolic process GO:0009057 161 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
positive regulation of protein catabolic process GO:0045732 34 0.025
peptidyl amino acid modification GO:0018193 105 0.024
negative regulation of cellular response to oxidative stress GO:1900408 1 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
digestive system development GO:0055123 149 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 51 0.024
defense response GO:0006952 300 0.024
protein targeting to nucleus GO:0044744 51 0.024
gastrulation involving germ band extension GO:0010004 36 0.024
negative regulation of catalytic activity GO:0043086 42 0.024
synapse organization GO:0050808 196 0.024
regulation of cell proliferation GO:0042127 163 0.024
positive regulation of cellular catabolic process GO:0031331 95 0.023
tissue death GO:0016271 102 0.023
proteolysis GO:0006508 192 0.023
purine nucleoside triphosphate catabolic process GO:0009146 108 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
mitotic g2 m transition checkpoint GO:0044818 70 0.023
regulation of embryonic development GO:0045995 68 0.023
regulation of protein kinase activity GO:0045859 51 0.023
nucleocytoplasmic transport GO:0006913 72 0.022
endomembrane system organization GO:0010256 119 0.022
response to oxidative stress GO:0006979 86 0.022
response to organic substance GO:0010033 284 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.022
developmental programmed cell death GO:0010623 138 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.022
carbohydrate derivative biosynthetic process GO:1901137 85 0.022
regulation of protein localization GO:0032880 76 0.022
response to oxygen containing compound GO:1901700 200 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
carbohydrate metabolic process GO:0005975 82 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.021
positive regulation of protein localization to nucleus GO:1900182 21 0.021
epithelial tube morphogenesis GO:0060562 88 0.021
chaeta development GO:0022416 97 0.021
cellular catabolic process GO:0044248 372 0.021
positive regulation of multicellular organismal process GO:0051240 143 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
Mouse
protein complex biogenesis GO:0070271 201 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
oocyte microtubule cytoskeleton organization GO:0016325 35 0.021
mrna metabolic process GO:0016071 124 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
Mouse
developmental maturation GO:0021700 172 0.020
positive regulation of catabolic process GO:0009896 105 0.020
positive regulation of transcription dna templated GO:0045893 266 0.020
Mouse
regulation of kinase activity GO:0043549 53 0.020
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.020
regulation of synapse structure and activity GO:0050803 128 0.020
nucleoside catabolic process GO:0009164 112 0.020
determination of adult lifespan GO:0008340 137 0.019
regulation of growth GO:0040008 233 0.019
regulation of protein ubiquitination GO:0031396 22 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
female germ line cyst formation GO:0048135 42 0.019
connective tissue development GO:0061448 3 0.019
glycoprotein biosynthetic process GO:0009101 41 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
single organism biosynthetic process GO:0044711 206 0.019
immune response GO:0006955 246 0.018
regulation of cytoplasmic transport GO:1903649 47 0.018
ras protein signal transduction GO:0007265 88 0.018
organelle assembly GO:0070925 198 0.018
negative regulation of cell development GO:0010721 62 0.018
anatomical structure homeostasis GO:0060249 97 0.018
localization of cell GO:0051674 257 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
peptidyl tyrosine modification GO:0018212 24 0.018
axoneme assembly GO:0035082 18 0.018
multicellular organismal aging GO:0010259 140 0.018
oocyte dorsal ventral axis specification GO:0007310 34 0.018
sulfur compound metabolic process GO:0006790 59 0.018
histone modification GO:0016570 106 0.018
dendrite development GO:0016358 204 0.017
intracellular signal transduction GO:0035556 300 0.017
Mouse
response to lipopolysaccharide GO:0032496 4 0.017
purine nucleoside monophosphate metabolic process GO:0009126 50 0.017
molting cycle chitin based cuticle GO:0007591 56 0.017
cellular homeostasis GO:0019725 80 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
regulation of response to external stimulus GO:0032101 115 0.017
actin mediated cell contraction GO:0070252 21 0.017
negative regulation of erbb signaling pathway GO:1901185 29 0.017
detection of external stimulus GO:0009581 66 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
immune effector process GO:0002252 98 0.016
mitochondrial fusion GO:0008053 7 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
cytoplasmic microtubule organization GO:0031122 22 0.016
mitochondrion localization GO:0051646 17 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.016
negative regulation of protein modification process GO:0031400 29 0.016
extracellular structure organization GO:0043062 46 0.016
positive regulation of neurotransmitter transport GO:0051590 2 0.016
embryonic morphogenesis GO:0048598 206 0.016
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
pigmentation GO:0043473 75 0.016
kidney development GO:0001822 3 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
response to wounding GO:0009611 94 0.015
positive regulation of mapk cascade GO:0043410 63 0.015
neuron death GO:0070997 27 0.015
associative learning GO:0008306 65 0.015
forebrain development GO:0030900 2 0.015
protein processing GO:0016485 68 0.015
catecholamine biosynthetic process GO:0042423 3 0.015
pole plasm mrna localization GO:0019094 49 0.015
sensory perception of mechanical stimulus GO:0050954 72 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
Mouse
nitrogen compound transport GO:0071705 85 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
embryonic pattern specification GO:0009880 174 0.015
response to superoxide GO:0000303 3 0.015
gtp metabolic process GO:0046039 72 0.015
tyrosine metabolic process GO:0006570 1 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
rhythmic behavior GO:0007622 76 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
rna 3 end processing GO:0031123 45 0.015
double strand break repair GO:0006302 26 0.014
regulation of synapse structural plasticity GO:0051823 3 0.014
response to other organism GO:0051707 293 0.014
regulation of multi organism process GO:0043900 131 0.014
negative regulation of nervous system development GO:0051961 92 0.014
regulation of organelle organization GO:0033043 196 0.014
actin filament polymerization GO:0030041 27 0.014
covalent chromatin modification GO:0016569 106 0.014
mitochondrial fission GO:0000266 8 0.014
positive regulation of transport GO:0051050 92 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
spindle assembly GO:0051225 80 0.014
jnk cascade GO:0007254 50 0.014
protein dna complex subunit organization GO:0071824 86 0.014
nucleoside monophosphate catabolic process GO:0009125 39 0.014
regulation of hydrolase activity GO:0051336 97 0.014
digestive tract development GO:0048565 149 0.013
interspecies interaction between organisms GO:0044419 16 0.013
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.013
positive regulation of protein modification process GO:0031401 58 0.013
positive regulation of molecular function GO:0044093 136 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.013
imaginal disc growth GO:0007446 37 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
induction of programmed cell death by hormones GO:0035081 12 0.013
chemical homeostasis GO:0048878 92 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.013
positive regulation of cell death GO:0010942 69 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
rhythmic process GO:0048511 106 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
regulation of protein localization to nucleus GO:1900180 29 0.012
regulation of vesicle mediated transport GO:0060627 59 0.012
glutamate secretion GO:0014047 1 0.012
dopamine metabolic process GO:0042417 7 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
regulation of intracellular protein transport GO:0033157 46 0.012
regulation of mapk cascade GO:0043408 92 0.012
gtp catabolic process GO:0006184 72 0.012
negative regulation of proteolysis GO:0045861 31 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
regulation of response to oxidative stress GO:1902882 4 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
membrane lipid metabolic process GO:0006643 22 0.012
salivary gland development GO:0007431 162 0.012
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.012
cell projection assembly GO:0030031 94 0.012
small rna loading onto risc GO:0070922 6 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.012
positive regulation of immune response GO:0050778 63 0.012
negative regulation of protein phosphorylation GO:0001933 17 0.012
body morphogenesis GO:0010171 2 0.012
regulation of proteolysis GO:0030162 87 0.012
regulation of pole plasm oskar mrna localization GO:0007317 27 0.012
atp catabolic process GO:0006200 38 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.011
sex differentiation GO:0007548 81 0.011
Mouse
larval development GO:0002164 104 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
male gamete generation GO:0048232 201 0.011
mrna processing GO:0006397 104 0.011
segmentation GO:0035282 207 0.011
peptidyl tyrosine phosphorylation GO:0018108 24 0.011
regulation of protein transport GO:0051223 57 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
positive regulation of protein transport GO:0051222 37 0.011
regulation of transferase activity GO:0051338 58 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.011
response to dsrna GO:0043331 15 0.011
purine nucleoside monophosphate catabolic process GO:0009128 38 0.011
regionalization GO:0003002 416 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
Mouse
vesicle organization GO:0016050 44 0.011
regulation of response to stress GO:0080134 200 0.011
protein heterooligomerization GO:0051291 4 0.011
response to endoplasmic reticulum stress GO:0034976 28 0.011
positive regulation of immune system process GO:0002684 68 0.011
induction of programmed cell death by ecdysone GO:0035078 12 0.011
regulation of multicellular organism growth GO:0040014 40 0.011
regulation of intracellular transport GO:0032386 64 0.011
germ line cyst formation GO:0048134 44 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
macromolecular complex assembly GO:0065003 256 0.010
detection of abiotic stimulus GO:0009582 66 0.010
protein maturation GO:0051604 71 0.010
learning GO:0007612 75 0.010
regulation of gtpase activity GO:0043087 44 0.010
ribonucleoside monophosphate catabolic process GO:0009158 39 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.010
necrotic cell death GO:0070265 1 0.010
erk1 and erk2 cascade GO:0070371 39 0.010

Ube3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.186
nervous system disease DOID:863 0 0.048
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036
bone disease DOID:0080001 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
cardiovascular system disease DOID:1287 0 0.013
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011