Drosophila melanogaster

163 known processes

Apc2 (Dmel_CG6193)

Adenomatous polyposis coli tumor suppressor homolog 2

(Aliases: d-APC2,Dmel\CG6193,dAPC2,E-APC,CG6193,E-APC dAPC2,apc2,dAPC2/E-APC,D-APC2,APC2,APC,dApc2)

Apc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment or maintenance of cell polarity GO:0007163 167 0.732
regionalization GO:0003002 416 0.628
transcription from rna polymerase ii promoter GO:0006366 368 0.584
Worm
epithelial cell differentiation GO:0030855 322 0.557
Mouse
epithelial cell development GO:0002064 274 0.555
blastoderm segmentation GO:0007350 159 0.532
neurological system process GO:0050877 358 0.517
embryonic pattern specification GO:0009880 174 0.473
axis specification GO:0009798 167 0.468
Mouse
actin cytoskeleton organization GO:0030036 206 0.432
oocyte axis specification GO:0007309 108 0.364
wing disc morphogenesis GO:0007472 344 0.352
wnt signaling pathway GO:0016055 98 0.316
regulation of cell differentiation GO:0045595 302 0.295
Mouse Fly
anterior posterior pattern specification GO:0009952 136 0.293
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.282
negative regulation of gene expression GO:0010629 387 0.281
Human
purine nucleoside triphosphate metabolic process GO:0009144 119 0.258
morphogenesis of an epithelium GO:0002009 276 0.256
localization of cell GO:0051674 257 0.240
negative regulation of rna metabolic process GO:0051253 251 0.231
post embryonic appendage morphogenesis GO:0035120 385 0.225
digestive system development GO:0055123 149 0.211
Worm
positive regulation of biosynthetic process GO:0009891 316 0.207
Worm
single organism cellular localization GO:1902580 180 0.206
Human
anterior posterior axis specification GO:0009948 109 0.202
regulation of immune system process GO:0002682 176 0.199
Mouse
appendage morphogenesis GO:0035107 397 0.187
tissue morphogenesis GO:0048729 297 0.185
cuticle development GO:0042335 86 0.184
glycosyl compound catabolic process GO:1901658 112 0.183
regulation of embryonic development GO:0045995 68 0.183
Worm
eye morphogenesis GO:0048592 260 0.182
Fly
protein localization GO:0008104 284 0.181
Human Mouse Worm Fly
cell maturation GO:0048469 144 0.180
positive regulation of response to stimulus GO:0048584 323 0.171
Worm
appendage development GO:0048736 401 0.169
negative regulation of developmental process GO:0051093 201 0.165
Mouse Worm Fly
ovarian follicle cell development GO:0030707 248 0.163
regulation of cellular amino acid metabolic process GO:0006521 0 0.161
Rat
regulation of pole plasm oskar mrna localization GO:0007317 27 0.156
actin filament organization GO:0007015 126 0.156
oocyte anterior posterior axis specification GO:0007314 72 0.156
regulation of cell development GO:0060284 215 0.152
Fly
segmentation GO:0035282 207 0.148
embryo development ending in birth or egg hatching GO:0009792 152 0.147
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.147
embryonic axis specification GO:0000578 107 0.146
digestive tract morphogenesis GO:0048546 127 0.145
Worm
imaginal disc derived appendage development GO:0048737 399 0.144
negative regulation of signaling GO:0023057 219 0.144
cell motility GO:0048870 251 0.142
Human Mouse Worm
oocyte construction GO:0007308 112 0.140
maternal determination of anterior posterior axis embryo GO:0008358 74 0.138
imaginal disc derived wing morphogenesis GO:0007476 337 0.138
regulation of anatomical structure morphogenesis GO:0022603 242 0.137
Mouse Worm Fly
regulation of organelle organization GO:0033043 196 0.135
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.135
regulation of mitotic cell cycle GO:0007346 190 0.134
Human Mouse
regulation of multicellular organismal development GO:2000026 414 0.134
Mouse Worm Fly
cuticle pattern formation GO:0035017 27 0.133
immune system process GO:0002376 347 0.127
Mouse
embryonic morphogenesis GO:0048598 206 0.126
establishment of planar polarity GO:0001736 87 0.121
digestive tract development GO:0048565 149 0.120
Worm
small molecule metabolic process GO:0044281 305 0.118
Rat
regulation of cellular component biogenesis GO:0044087 201 0.115
Human Mouse Fly
anterior posterior axis specification embryo GO:0008595 103 0.115
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.113
Worm
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.111
regulation of developmental growth GO:0048638 174 0.105
positive regulation of signal transduction GO:0009967 223 0.105
Worm
protein modification process GO:0036211 438 0.101
Human
cellular protein localization GO:0034613 160 0.100
Human Mouse Worm Fly
organelle localization GO:0051640 148 0.099
purine ribonucleotide catabolic process GO:0009154 109 0.097
cell proliferation GO:0008283 299 0.097
tube morphogenesis GO:0035239 191 0.097
Worm
tube development GO:0035295 244 0.095
Worm
growth GO:0040007 359 0.094
gastrulation involving germ band extension GO:0010004 36 0.094
germarium derived egg chamber formation GO:0007293 101 0.091
negative regulation of transcription dna templated GO:0045892 237 0.090
regulation of embryonic cell shape GO:0016476 30 0.090
Worm
regulation of cell cycle phase transition GO:1901987 130 0.089
Human
regulation of transport GO:0051049 181 0.088
Human
negative regulation of response to stimulus GO:0048585 258 0.088
negative regulation of signal transduction GO:0009968 206 0.088
gastrulation GO:0007369 70 0.087
Worm
compound eye development GO:0048749 307 0.086
Fly
respiratory system development GO:0060541 213 0.085
ribonucleotide metabolic process GO:0009259 145 0.085
epidermal growth factor receptor signaling pathway GO:0007173 58 0.085
mitotic spindle organization GO:0007052 220 0.084
Worm
regulation of cell adhesion GO:0030155 27 0.084
Mouse
regulation of response to stress GO:0080134 200 0.083
negative regulation of cellular metabolic process GO:0031324 382 0.080
Human Mouse
regulation of cell morphogenesis GO:0022604 163 0.080
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.078
phosphorylation GO:0016310 294 0.077
Human Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.077
developmental growth GO:0048589 280 0.076
establishment of tissue polarity GO:0007164 87 0.076
positive regulation of transport GO:0051050 92 0.076
oocyte differentiation GO:0009994 145 0.076
negative regulation of cellular biosynthetic process GO:0031327 277 0.076
positive regulation of cellular component organization GO:0051130 156 0.075
Human Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.074
single organism intracellular transport GO:1902582 207 0.074
Human Worm
negative regulation of multicellular organismal process GO:0051241 142 0.073
Mouse Worm Fly
organonitrogen compound metabolic process GO:1901564 318 0.072
Rat
cell death GO:0008219 279 0.071
Human Mouse Fly
regulation of cellular amine metabolic process GO:0033238 3 0.071
Rat
oocyte development GO:0048599 124 0.070
negative regulation of nucleic acid templated transcription GO:1903507 240 0.070
positive regulation of macromolecule metabolic process GO:0010604 405 0.068
regulation of cellular protein metabolic process GO:0032268 243 0.067
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.066
positive regulation of intracellular signal transduction GO:1902533 116 0.066
axonogenesis GO:0007409 290 0.065
axon development GO:0061564 297 0.065
positive regulation of cellular amine metabolic process GO:0033240 0 0.064
regulation of programmed cell death GO:0043067 152 0.064
Human Mouse Fly
response to biotic stimulus GO:0009607 294 0.063
instar larval development GO:0002168 55 0.063
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.063
regulation of cell cycle GO:0051726 291 0.063
Human Mouse
regulation of epithelial cell proliferation GO:0050678 4 0.062
Mouse
cytoplasm organization GO:0007028 64 0.062
tripartite regional subdivision GO:0007351 103 0.061
enzyme linked receptor protein signaling pathway GO:0007167 179 0.061
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.059
dorsal appendage formation GO:0046843 47 0.058
biological adhesion GO:0022610 138 0.058
negative regulation of cell communication GO:0010648 223 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.057
Worm
regulation of cellular localization GO:0060341 136 0.057
Human Mouse
carbohydrate derivative catabolic process GO:1901136 118 0.056
regulation of reproductive process GO:2000241 54 0.056
Mouse
establishment of localization in cell GO:0051649 402 0.055
vesicle mediated transport GO:0016192 381 0.055
Worm
proteolysis GO:0006508 192 0.055
Human Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.054
regulation of nervous system development GO:0051960 248 0.054
response to radiation GO:0009314 155 0.054
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.053
morphogenesis of embryonic epithelium GO:0016331 94 0.052
response to ionizing radiation GO:0010212 32 0.052
cellular ketone metabolic process GO:0042180 24 0.052
Rat
single organism behavior GO:0044708 391 0.052
gastrulation with mouth forming first GO:0001703 36 0.051
regulation of mapk cascade GO:0043408 92 0.051
Mouse
immune response GO:0006955 246 0.051
response to external biotic stimulus GO:0043207 293 0.051
dorsal closure GO:0007391 79 0.050
cell division GO:0051301 248 0.050
Human Mouse Worm
positive regulation of cell communication GO:0010647 250 0.050
Worm
nucleotide catabolic process GO:0009166 109 0.049
purine nucleotide catabolic process GO:0006195 109 0.049
regulation of cell death GO:0010941 173 0.049
Human Mouse Fly
regulation of molecular function GO:0065009 217 0.049
Human
stem cell proliferation GO:0072089 88 0.048
pole plasm mrna localization GO:0019094 49 0.048
response to abiotic stimulus GO:0009628 341 0.047
ribonucleoside metabolic process GO:0009119 127 0.047
heterocycle catabolic process GO:0046700 166 0.046
hindbrain development GO:0030902 2 0.046
actin filament based process GO:0030029 220 0.046
compound eye morphogenesis GO:0001745 249 0.046
Fly
positive regulation of molecular function GO:0044093 136 0.046
periodic partitioning GO:0007365 29 0.045
defense response to other organism GO:0098542 225 0.044
regulation of intracellular signal transduction GO:1902531 236 0.044
Mouse
dorsal ventral pattern formation GO:0009953 133 0.044
Mouse
organelle fission GO:0048285 340 0.043
Human Mouse
positive regulation of cell proliferation GO:0008284 47 0.042
death GO:0016265 284 0.042
Human Mouse Fly
pole plasm assembly GO:0007315 61 0.042
stem cell development GO:0048864 79 0.042
Mouse
cell cycle phase transition GO:0044770 140 0.042
Human Mouse
cognition GO:0050890 141 0.041
response to organic substance GO:0010033 284 0.041
Rat
regulation of hydrolase activity GO:0051336 97 0.041
nucleoside phosphate catabolic process GO:1901292 110 0.041
protein polymerization GO:0051258 42 0.041
Mouse
actin filament bundle organization GO:0061572 28 0.040
reproductive structure development GO:0048608 74 0.040
Mouse
mitotic cytokinesis GO:0000281 50 0.039
Human Mouse
intracellular signal transduction GO:0035556 300 0.039
Mouse
regulation of organ morphogenesis GO:2000027 78 0.039
Mouse Fly
regulation of growth GO:0040008 233 0.038
negative regulation of wnt signaling pathway GO:0030178 28 0.038
regulation of phosphorylation GO:0042325 147 0.038
Human Mouse
cell migration GO:0016477 238 0.037
Human Mouse Worm
cellular protein modification process GO:0006464 438 0.037
Human
positive regulation of organelle organization GO:0010638 65 0.037
Mouse
response to other organism GO:0051707 293 0.037
positive regulation of catabolic process GO:0009896 105 0.037
negative regulation of biosynthetic process GO:0009890 277 0.036
nuclear import GO:0051170 51 0.035
Human
cellular response to oxygen containing compound GO:1901701 79 0.035
imaginal disc derived female genitalia development GO:0007486 6 0.035
regulation of mitotic cell cycle phase transition GO:1901990 130 0.035
Human
regulation of cell cycle process GO:0010564 181 0.035
Human Mouse
organonitrogen compound catabolic process GO:1901565 128 0.035
ribonucleoside triphosphate catabolic process GO:0009203 108 0.035
positive regulation of protein metabolic process GO:0051247 128 0.035
apoptotic process GO:0006915 159 0.034
Human Mouse
regulation of phosphate metabolic process GO:0019220 210 0.034
Human Mouse
cellular protein complex assembly GO:0043623 71 0.034
Mouse
establishment of cell polarity GO:0030010 40 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.034
Worm
protein import into nucleus GO:0006606 51 0.033
Human
intracellular protein transport GO:0006886 104 0.033
Human Worm Fly
negative regulation of protein modification process GO:0031400 29 0.033
Human
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.033
camera type eye development GO:0043010 4 0.032
Mouse
protein maturation GO:0051604 71 0.032
Human
positive regulation of developmental process GO:0051094 143 0.032
Mouse
asymmetric cell division GO:0008356 37 0.032
Worm
malpighian tubule development GO:0072002 64 0.032
mesoderm development GO:0007498 78 0.032
defense response to bacterium GO:0042742 178 0.031
pole plasm rna localization GO:0007316 52 0.031
regulation of multi organism process GO:0043900 131 0.031
body morphogenesis GO:0010171 2 0.031
Worm
regulation of protein serine threonine kinase activity GO:0071900 25 0.031
Human
regulation of oocyte development GO:0060281 27 0.031
organic substance catabolic process GO:1901575 308 0.031
eggshell chorion assembly GO:0007306 66 0.031
regulation of protein metabolic process GO:0051246 256 0.030
purine containing compound catabolic process GO:0072523 112 0.029
catabolic process GO:0009056 409 0.029
purine ribonucleoside metabolic process GO:0046128 127 0.029
endocytosis GO:0006897 310 0.029
Worm
cellularization GO:0007349 90 0.029
stem cell maintenance GO:0019827 67 0.029
Mouse
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.029
single organismal cell cell adhesion GO:0016337 45 0.029
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
gene silencing GO:0016458 138 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
Human Mouse
organic cyclic compound catabolic process GO:1901361 168 0.028
nucleotide metabolic process GO:0009117 161 0.028
protein phosphorylation GO:0006468 169 0.028
Human
positive regulation of signaling GO:0023056 243 0.027
Worm
cellular response to chemical stimulus GO:0070887 199 0.027
Rat
eggshell formation GO:0030703 105 0.027
organic substance transport GO:0071702 257 0.027
Human Worm Fly
positive regulation of phosphorylation GO:0042327 87 0.027
positive regulation of immune system process GO:0002684 68 0.027
positive regulation of immune response GO:0050778 63 0.027
chromosome segregation GO:0007059 157 0.027
Human Mouse
ribonucleoside triphosphate metabolic process GO:0009199 119 0.027
ribonucleotide catabolic process GO:0009261 109 0.027
regulation of wnt signaling pathway GO:0030111 68 0.026
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.026
learning or memory GO:0007611 141 0.026
regulation of bmp signaling pathway GO:0030510 23 0.026
regulation of intracellular protein transport GO:0033157 46 0.026
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.026
establishment of organelle localization GO:0051656 122 0.025
regulation of cell shape GO:0008360 113 0.025
Worm
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.025
mitotic nuclear division GO:0007067 213 0.025
Human Mouse
single organism catabolic process GO:0044712 228 0.025
Human Mouse
phenol containing compound metabolic process GO:0018958 57 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
mitotic cell cycle phase transition GO:0044772 138 0.025
Human Mouse
positive regulation of multi organism process GO:0043902 40 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
nucleoside triphosphate metabolic process GO:0009141 120 0.025
purine ribonucleoside catabolic process GO:0046130 112 0.025
regulation of innate immune response GO:0045088 71 0.025
taxis GO:0042330 304 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
Worm
nucleoside catabolic process GO:0009164 112 0.024
cell fate specification GO:0001708 71 0.024
Worm
cellular nitrogen compound catabolic process GO:0044270 165 0.024
bmp signaling pathway GO:0030509 27 0.024
aromatic compound catabolic process GO:0019439 166 0.024
dna metabolic process GO:0006259 227 0.024
programmed cell death GO:0012501 257 0.024
Human Mouse Fly
regulation of nucleocytoplasmic transport GO:0046822 35 0.024
Human
oxoacid metabolic process GO:0043436 103 0.023
Rat
head development GO:0060322 135 0.023
sensory organ morphogenesis GO:0090596 260 0.023
Fly
regulation of protein modification process GO:0031399 112 0.023
Human
regulation of embryonic pattern specification GO:1902875 27 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
dorsal ventral axis specification GO:0009950 66 0.023
reproductive system development GO:0061458 74 0.023
Mouse
epidermis development GO:0008544 65 0.023
Mouse
protein targeting GO:0006605 64 0.023
Human
positive regulation of protein modification process GO:0031401 58 0.023
protein localization to nucleus GO:0034504 55 0.023
Human
mapk cascade GO:0000165 107 0.023
Mouse
head involution GO:0008258 35 0.023
cellular catabolic process GO:0044248 372 0.023
Human Mouse
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
negative regulation of molecular function GO:0044092 51 0.023
Human
purine ribonucleotide metabolic process GO:0009150 145 0.023
regulation of localization GO:0032879 275 0.022
Human Mouse Worm
response to bacterium GO:0009617 198 0.022
renal system development GO:0072001 72 0.022
Mouse
spindle organization GO:0007051 253 0.022
Worm
ribonucleoside catabolic process GO:0042454 112 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.022
purine containing compound metabolic process GO:0072521 155 0.022
regulation of defense response to bacterium GO:1900424 30 0.022
defense response to fungus GO:0050832 48 0.022
negative regulation of cell cell adhesion GO:0022408 8 0.022
regulation of toll signaling pathway GO:0008592 17 0.022
cytokinesis GO:0000910 90 0.021
Human Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
Worm
negative regulation of cell cycle process GO:0010948 109 0.021
Human
non canonical wnt signaling pathway GO:0035567 8 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
Rat
purine nucleoside catabolic process GO:0006152 112 0.021
positive regulation of cell cycle GO:0045787 43 0.021
actin filament bundle assembly GO:0051017 26 0.021
secondary metabolic process GO:0019748 75 0.021
morphogenesis of a polarized epithelium GO:0001738 93 0.020
protein complex assembly GO:0006461 200 0.020
Human Mouse Fly
positive regulation of jun kinase activity GO:0043507 4 0.020
immune response regulating signaling pathway GO:0002764 2 0.020
ventral furrow formation GO:0007370 17 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
Rat
antimicrobial peptide biosynthetic process GO:0002777 38 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.020
positive regulation of protein phosphorylation GO:0001934 34 0.020
cell substrate adhesion GO:0031589 10 0.020
defense response to gram negative bacterium GO:0050829 94 0.020
nuclear transport GO:0051169 72 0.020
Human Worm
development of primary sexual characteristics GO:0045137 50 0.020
secretion by cell GO:0032940 101 0.020
anatomical structure homeostasis GO:0060249 97 0.020
Mouse
ameboidal type cell migration GO:0001667 151 0.019
camera type eye morphogenesis GO:0048593 2 0.019
organophosphate catabolic process GO:0046434 112 0.019
single organism nuclear import GO:1902593 51 0.019
Human
regulation of phosphatase activity GO:0010921 3 0.019
regulation of transposition GO:0010528 13 0.019
negative regulation of cell cycle GO:0045786 116 0.019
Human
response to light stimulus GO:0009416 124 0.019
developmental maturation GO:0021700 172 0.019
developmental pigmentation GO:0048066 68 0.019
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
regulation of catalytic activity GO:0050790 185 0.019
Human
positive regulation of protein transport GO:0051222 37 0.019
positive regulation of mapk cascade GO:0043410 63 0.018
positive regulation of gene expression GO:0010628 290 0.018
Worm
regulation of catabolic process GO:0009894 170 0.018
regulation of cell maturation GO:1903429 27 0.018
oocyte microtubule cytoskeleton organization GO:0016325 35 0.018
nuclear division GO:0000280 332 0.018
Human Mouse
negative regulation of cell death GO:0060548 81 0.018
Mouse Fly
sensory perception GO:0007600 196 0.018
long term memory GO:0007616 62 0.018
muscle organ development GO:0007517 127 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
chorion containing eggshell formation GO:0007304 105 0.018
toll signaling pathway GO:0008063 25 0.018
protein transport GO:0015031 155 0.017
Human Worm Fly
somatic stem cell division GO:0048103 37 0.017
protein import GO:0017038 55 0.017
Human
intracellular mrna localization GO:0008298 66 0.017
meiotic nuclear division GO:0007126 151 0.017
cytoskeleton dependent cytokinesis GO:0061640 81 0.017
Human Mouse
cell adhesion GO:0007155 136 0.017
regulation of cellular response to oxidative stress GO:1900407 4 0.017
regulation of intracellular transport GO:0032386 64 0.017
Human
canonical wnt signaling pathway GO:0060070 21 0.017
Human Mouse
positive regulation of melanization defense response GO:0035008 1 0.017
open tracheal system development GO:0007424 204 0.017
regulation of response to external stimulus GO:0032101 115 0.017
epithelial cell migration GO:0010631 148 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.016
positive regulation of intracellular transport GO:0032388 42 0.016
response to growth factor GO:0070848 31 0.016
Rat
innate immune response GO:0045087 144 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
Mouse Fly
regulation of cell junction assembly GO:1901888 2 0.016
segment polarity determination GO:0007367 25 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
nucleus localization GO:0051647 34 0.016
protein targeting to nucleus GO:0044744 51 0.016
Human
mesenchymal cell differentiation GO:0048762 1 0.016
endodermal cell fate commitment GO:0001711 3 0.016
Worm
nucleoside metabolic process GO:0009116 127 0.016
regulation of cell division GO:0051302 72 0.016
Human Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.016
peptidyl threonine modification GO:0018210 3 0.016
molting cycle GO:0042303 56 0.015
positive regulation of stem cell differentiation GO:2000738 3 0.015
regulation of response to biotic stimulus GO:0002831 63 0.015
regulation of immune response GO:0050776 118 0.015
positive regulation of cell cycle process GO:0090068 28 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
Human Mouse
regulation of gene expression epigenetic GO:0040029 128 0.015
kidney development GO:0001822 3 0.015
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.014
regulation of compound eye pigmentation GO:0048076 7 0.014
cell cycle arrest GO:0007050 4 0.014
Human
regulation of actin filament based process GO:0032970 42 0.014
actin mediated cell contraction GO:0070252 21 0.014
negative regulation of nervous system development GO:0051961 92 0.014
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.014
meiosis i GO:0007127 59 0.014
regulation of cell cell adhesion GO:0022407 21 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
Worm
response to organic cyclic compound GO:0014070 89 0.014
fertilization GO:0009566 26 0.014
regulation of jnk cascade GO:0046328 40 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
Worm
positive regulation of antimicrobial peptide production GO:0002225 28 0.014
regulation of cell proliferation GO:0042127 163 0.014
Human Mouse
regulation of cell motility GO:2000145 23 0.014
Human Mouse Worm
response to oxygen containing compound GO:1901700 200 0.014
Rat
macromolecular complex assembly GO:0065003 256 0.014
Human Mouse Fly
regulation of cellular component movement GO:0051270 42 0.014
Human Mouse Worm
positive regulation of mitotic cell cycle GO:0045931 34 0.014
cell junction assembly GO:0034329 42 0.014
ras protein signal transduction GO:0007265 88 0.014
regulation of secretion GO:0051046 44 0.014
positive regulation of secretion GO:0051047 22 0.014
stem cell division GO:0017145 69 0.014
regulation of organ growth GO:0046620 42 0.013
regulation of defense response GO:0031347 102 0.013
activation of jun kinase activity GO:0007257 3 0.013
eye development GO:0001654 323 0.013
Mouse Fly
cellular amine metabolic process GO:0044106 12 0.013
Rat
melanin metabolic process GO:0006582 47 0.013
cell cell junction assembly GO:0007043 38 0.013
immune response activating signal transduction GO:0002757 2 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
axon guidance GO:0007411 233 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.013
neuromuscular junction development GO:0007528 149 0.013
larval development GO:0002164 104 0.013
spindle localization GO:0051653 22 0.013
regulation of developmental pigmentation GO:0048070 24 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
Worm
pole plasm protein localization GO:0007318 10 0.013
lateral inhibition GO:0046331 206 0.012
regulation of microtubule based process GO:0032886 49 0.012
Human Mouse
actin polymerization or depolymerization GO:0008154 31 0.012
establishment of spindle localization GO:0051293 22 0.012
erbb signaling pathway GO:0038127 58 0.012
negative regulation of developmental growth GO:0048640 64 0.012
substrate dependent cell migration GO:0006929 3 0.012
regulation of ion transport GO:0043269 39 0.012
intracellular transport GO:0046907 228 0.012
Human Worm Fly
regulation of protein phosphorylation GO:0001932 64 0.012
Human
cellular protein catabolic process GO:0044257 83 0.012
Human Mouse
myoblast fusion GO:0007520 43 0.012
positive regulation of protein binding GO:0032092 1 0.012
regulation of synapse assembly GO:0051963 94 0.012
defense response GO:0006952 300 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
Human Worm
guanosine containing compound catabolic process GO:1901069 74 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
Human
unidimensional cell growth GO:0009826 15 0.012
sister chromatid segregation GO:0000819 92 0.012
Human Mouse
posttranscriptional gene silencing by rna GO:0035194 45 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
regulation of locomotion GO:0040012 42 0.012
Human Mouse Worm
nucleoside triphosphate catabolic process GO:0009143 108 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
Worm
cellular macromolecule catabolic process GO:0044265 136 0.012
Human Mouse
cellular response to endogenous stimulus GO:0071495 80 0.011
Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
jnk cascade GO:0007254 50 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
spermatogenesis GO:0007283 200 0.011
regulation of neurogenesis GO:0050767 158 0.011
pronuclear migration GO:0035046 4 0.011
epithelium migration GO:0090132 148 0.011
epithelial cell morphogenesis GO:0003382 25 0.011
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
Mouse
immune effector process GO:0002252 98 0.011
positive regulation of kinase activity GO:0033674 25 0.011
regulation of neuron differentiation GO:0045664 103 0.011
pole plasm oskar mrna localization GO:0045451 46 0.011
regulation of protein localization GO:0032880 76 0.011
Human Mouse
response to lipopolysaccharide GO:0032496 4 0.011

Apc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.017
Human
disease of cellular proliferation DOID:14566 0 0.017
Human
organ system cancer DOID:0050686 0 0.012
Human