Drosophila melanogaster

41 known processes

Saf-B (Dmel_CG6995)

Scaffold attachment factor B

(Aliases: CG6995,SAF-B,saf-b,cg6995,Dmel\CG6995,LD22822)

Saf-B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular biosynthetic process GO:0031328 316 0.284
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.264
ras protein signal transduction GO:0007265 88 0.216
positive regulation of rna metabolic process GO:0051254 271 0.170
negative regulation of gene expression epigenetic GO:0045814 77 0.167
mrna metabolic process GO:0016071 124 0.159
positive regulation of nucleic acid templated transcription GO:1903508 266 0.157
intracellular signal transduction GO:0035556 300 0.145
body morphogenesis GO:0010171 2 0.142
positive regulation of rna biosynthetic process GO:1902680 266 0.133
positive regulation of transcription dna templated GO:0045893 266 0.127
regulation of small gtpase mediated signal transduction GO:0051056 93 0.117
transcription from rna polymerase ii promoter GO:0006366 368 0.116
imaginal disc derived appendage development GO:0048737 399 0.114
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.110
dendrite development GO:0016358 204 0.106
negative regulation of rna biosynthetic process GO:1902679 240 0.104
endocytosis GO:0006897 310 0.103
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.094
positive regulation of signaling GO:0023056 243 0.089
negative regulation of transcription dna templated GO:0045892 237 0.086
carbohydrate derivative catabolic process GO:1901136 118 0.085
regulation of mrna splicing via spliceosome GO:0048024 64 0.084
small gtpase mediated signal transduction GO:0007264 88 0.083
regulation of ras protein signal transduction GO:0046578 93 0.083
regulation of mrna metabolic process GO:1903311 72 0.082
mrna splicing via spliceosome GO:0000398 73 0.079
cell division GO:0051301 248 0.079
regulation of cell morphogenesis GO:0022604 163 0.078
regulation of gene expression epigenetic GO:0040029 128 0.078
regulation of rna splicing GO:0043484 69 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.073
compound eye development GO:0048749 307 0.072
positive regulation of developmental process GO:0051094 143 0.069
meiotic cell cycle GO:0051321 171 0.069
regulation of phosphorus metabolic process GO:0051174 210 0.069
positive regulation of cell communication GO:0010647 250 0.066
multicellular organismal reproductive behavior GO:0033057 110 0.065
positive regulation of signal transduction GO:0009967 223 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.064
positive regulation of intracellular signal transduction GO:1902533 116 0.061
positive regulation of biosynthetic process GO:0009891 316 0.060
organonitrogen compound metabolic process GO:1901564 318 0.059
negative regulation of gene expression GO:0010629 387 0.057
cellular response to organic substance GO:0071310 132 0.056
localization of cell GO:0051674 257 0.056
single organism behavior GO:0044708 391 0.056
vesicle mediated transport GO:0016192 381 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.055
chromatin silencing GO:0006342 76 0.055
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.055
negative regulation of nucleic acid templated transcription GO:1903507 240 0.055
purine containing compound metabolic process GO:0072521 155 0.054
response to organic cyclic compound GO:0014070 89 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.053
small molecule metabolic process GO:0044281 305 0.052
eye development GO:0001654 323 0.052
negative regulation of cellular metabolic process GO:0031324 382 0.052
embryo development ending in birth or egg hatching GO:0009792 152 0.051
negative regulation of rna metabolic process GO:0051253 251 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.049
negative regulation of multicellular organismal process GO:0051241 142 0.049
response to organic substance GO:0010033 284 0.048
intracellular protein transport GO:0006886 104 0.047
nucleoside metabolic process GO:0009116 127 0.047
regulation of phosphate metabolic process GO:0019220 210 0.047
cell death GO:0008219 279 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.045
negative regulation of biosynthetic process GO:0009890 277 0.044
cell migration GO:0016477 238 0.043
purine nucleoside metabolic process GO:0042278 127 0.043
regulation of mapk cascade GO:0043408 92 0.043
positive regulation of phosphate metabolic process GO:0045937 139 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.042
nucleotide metabolic process GO:0009117 161 0.042
regulation of erk1 and erk2 cascade GO:0070372 39 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.041
cellular nitrogen compound catabolic process GO:0044270 165 0.040
regulation of intracellular signal transduction GO:1902531 236 0.038
wing disc morphogenesis GO:0007472 344 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
cell motility GO:0048870 251 0.038
positive regulation of gene expression GO:0010628 290 0.037
positive regulation of ras protein signal transduction GO:0046579 43 0.037
response to endogenous stimulus GO:0009719 119 0.036
negative regulation of signaling GO:0023057 219 0.036
multi organism behavior GO:0051705 175 0.035
cellular macromolecule localization GO:0070727 220 0.035
dna templated transcription elongation GO:0006354 18 0.035
multi organism reproductive behavior GO:0044705 121 0.034
nucleoside triphosphate catabolic process GO:0009143 108 0.034
heterocycle catabolic process GO:0046700 166 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.032
regulation of protein localization GO:0032880 76 0.031
enzyme linked receptor protein signaling pathway GO:0007167 179 0.031
positive regulation of phosphorus metabolic process GO:0010562 139 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
death GO:0016265 284 0.030
signal transduction by phosphorylation GO:0023014 107 0.030
regulation of organelle organization GO:0033043 196 0.030
mapk cascade GO:0000165 107 0.030
glycosyl compound metabolic process GO:1901657 127 0.029
ribonucleotide metabolic process GO:0009259 145 0.028
purine nucleoside triphosphate metabolic process GO:0009144 119 0.028
peptidyl amino acid modification GO:0018193 105 0.028
imaginal disc derived leg morphogenesis GO:0007480 80 0.028
single organism catabolic process GO:0044712 228 0.028
ribonucleoside metabolic process GO:0009119 127 0.028
regulation of programmed cell death GO:0043067 152 0.027
stem cell development GO:0048864 79 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
ribose phosphate metabolic process GO:0019693 145 0.027
rna splicing GO:0008380 83 0.027
hematopoietic stem cell differentiation GO:0060218 1 0.026
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.026
erk1 and erk2 cascade GO:0070371 39 0.026
regulation of cell differentiation GO:0045595 302 0.026
aromatic compound catabolic process GO:0019439 166 0.026
g2 dna damage checkpoint GO:0031572 69 0.026
catabolic process GO:0009056 409 0.025
negative regulation of signal transduction GO:0009968 206 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
single organism cellular localization GO:1902580 180 0.025
regulation of cell cycle process GO:0010564 181 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
regulation of cell proliferation GO:0042127 163 0.024
purine nucleoside catabolic process GO:0006152 112 0.024
regulation of phosphorylation GO:0042325 147 0.024
reproductive behavior GO:0019098 122 0.024
regulation of mrna processing GO:0050684 71 0.023
ribonucleoside catabolic process GO:0042454 112 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
regulation of molecular function GO:0065009 217 0.022
chromatin remodeling GO:0006338 72 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
cellular catabolic process GO:0044248 372 0.022
positive regulation of mapk cascade GO:0043410 63 0.021
cell proliferation GO:0008283 299 0.021
regulation of cell division GO:0051302 72 0.021
establishment of localization in cell GO:0051649 402 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
cellular response to chemical stimulus GO:0070887 199 0.020
phagocytosis GO:0006909 215 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
negative regulation of developmental process GO:0051093 201 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.019
multi multicellular organism process GO:0044706 123 0.019
larval development GO:0002164 104 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
cell adhesion GO:0007155 136 0.018
gene silencing by rna GO:0031047 57 0.018
organophosphate metabolic process GO:0019637 195 0.018
development of primary sexual characteristics GO:0045137 50 0.017
programmed cell death GO:0012501 257 0.017
mrna processing GO:0006397 104 0.017
genitalia development GO:0048806 26 0.017
reproductive structure development GO:0048608 74 0.017
dendrite morphogenesis GO:0048813 199 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
cellular ketone metabolic process GO:0042180 24 0.017
protein transport GO:0015031 155 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
protein localization GO:0008104 284 0.016
organic substance transport GO:0071702 257 0.016
regulation of cellular localization GO:0060341 136 0.016
appendage development GO:0048736 401 0.016
regulation of neurogenesis GO:0050767 158 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
hindbrain development GO:0030902 2 0.015
nucleoside catabolic process GO:0009164 112 0.015
methylation GO:0032259 47 0.015
regulation of localization GO:0032879 275 0.015
phosphorylation GO:0016310 294 0.015
nucleotide catabolic process GO:0009166 109 0.015
regulation of chromatin modification GO:1903308 28 0.015
peptidyl lysine methylation GO:0018022 16 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
response to oxygen containing compound GO:1901700 200 0.014
macromolecular complex assembly GO:0065003 256 0.014
nuclear division GO:0000280 332 0.014
histone h3 k4 methylation GO:0051568 16 0.014
purine nucleoside monophosphate metabolic process GO:0009126 50 0.014
positive regulation of molecular function GO:0044093 136 0.014
positive regulation of growth GO:0045927 75 0.014
response to abiotic stimulus GO:0009628 341 0.014
aging GO:0007568 143 0.014
organic substance catabolic process GO:1901575 308 0.013
regulation of developmental growth GO:0048638 174 0.013
taxis GO:0042330 304 0.013
appendage morphogenesis GO:0035107 397 0.013
cellular response to hormone stimulus GO:0032870 44 0.013
regulation of catalytic activity GO:0050790 185 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
gonad development GO:0008406 50 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
organic acid metabolic process GO:0006082 103 0.013
positive regulation of small gtpase mediated signal transduction GO:0051057 43 0.013
peptidyl lysine modification GO:0018205 57 0.013
response to temperature stimulus GO:0009266 106 0.012
chromatin organization GO:0006325 207 0.012
rna catabolic process GO:0006401 37 0.012
regulation of calcium ion transmembrane transport GO:1903169 2 0.012
gene silencing GO:0016458 138 0.012
reproductive system development GO:0061458 74 0.012
regulation of chromatin silencing GO:0031935 36 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
epidermal growth factor receptor signaling pathway GO:0007173 58 0.012
mitotic nuclear division GO:0007067 213 0.012
tube development GO:0035295 244 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
gtp metabolic process GO:0046039 72 0.012
eye morphogenesis GO:0048592 260 0.012
cellular response to insulin stimulus GO:0032869 28 0.012
peptidyl lysine trimethylation GO:0018023 6 0.011
protein localization to organelle GO:0033365 82 0.011
organophosphate catabolic process GO:0046434 112 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
single organism intracellular transport GO:1902582 207 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
chromatin modification GO:0016568 147 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of growth GO:0040008 233 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
regulation of nuclear division GO:0051783 58 0.011
jak stat cascade GO:0007259 49 0.010
histone methylation GO:0016571 40 0.010
establishment of protein localization GO:0045184 163 0.010
regulation of cell development GO:0060284 215 0.010
oviposition GO:0018991 19 0.010
sensory organ morphogenesis GO:0090596 260 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
aromatic amino acid family metabolic process GO:0009072 3 0.010
regulation of dna templated transcription elongation GO:0032784 17 0.010
response to nitrogen compound GO:1901698 90 0.010
regulation of nervous system development GO:0051960 248 0.010
regulation of cell shape GO:0008360 113 0.010

Saf-B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.048
disease of cellular proliferation DOID:14566 0 0.048
disease of anatomical entity DOID:7 0 0.039
organ system cancer DOID:0050686 0 0.031
nervous system disease DOID:863 0 0.018