Drosophila melanogaster

80 known processes

HP1c (Dmel_CG6990)

CG6990 gene product from transcript CG6990-RA

(Aliases: hp1c,HP1,CG6990,HP1C,Hp1c,Dmel\CG6990)

HP1c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.531
Fly
negative regulation of rna metabolic process GO:0051253 251 0.422
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.391
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.368
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.356
negative regulation of biosynthetic process GO:0009890 277 0.355
mrna cis splicing via spliceosome GO:0045292 1 0.335
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.308
Fly
chromatin modification GO:0016568 147 0.305
Fly
chromatin organization GO:0006325 207 0.284
Fly
positive regulation of transcription dna templated GO:0045893 266 0.207
Fly
positive regulation of rna metabolic process GO:0051254 271 0.195
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.195
Fly
negative regulation of gene expression GO:0010629 387 0.194
negative regulation of cellular biosynthetic process GO:0031327 277 0.190
transcription from rna polymerase ii promoter GO:0006366 368 0.189
positive regulation of biosynthetic process GO:0009891 316 0.181
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.178
negative regulation of cellular metabolic process GO:0031324 382 0.173
peptidyl lysine modification GO:0018205 57 0.155
Fly
regulation of cell cycle GO:0051726 291 0.147
negative regulation of transcription dna templated GO:0045892 237 0.147
cell death GO:0008219 279 0.145
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.144
Fly
regulation of cell differentiation GO:0045595 302 0.138
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.126
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.123
Fly
programmed cell death GO:0012501 257 0.110
Fly
regulation of apoptotic process GO:0042981 130 0.108
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.099
Fly
histone modification GO:0016570 106 0.091
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.086
positive regulation of gene expression GO:0010628 290 0.078
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.076
Fly
rna splicing via transesterification reactions GO:0000375 73 0.072
organelle assembly GO:0070925 198 0.071
establishment of localization in cell GO:0051649 402 0.070
organelle fission GO:0048285 340 0.065
mrna metabolic process GO:0016071 124 0.064
small molecule metabolic process GO:0044281 305 0.064
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.062
rna splicing GO:0008380 83 0.060
catabolic process GO:0009056 409 0.060
regulation of meiosis GO:0040020 3 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.057
regulation of multicellular organismal development GO:2000026 414 0.056
death GO:0016265 284 0.053
Fly
cellular catabolic process GO:0044248 372 0.049
chromatin remodeling GO:0006338 72 0.048
Fly
cellular protein modification process GO:0006464 438 0.046
Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.045
regulation of protein metabolic process GO:0051246 256 0.044
Fly
nucleocytoplasmic transport GO:0006913 72 0.043
organic substance catabolic process GO:1901575 308 0.043
mrna processing GO:0006397 104 0.040
actin filament based process GO:0030029 220 0.040
negative regulation of cell differentiation GO:0045596 143 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.038
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.036
Fly
immune system process GO:0002376 347 0.036
cellular response to dna damage stimulus GO:0006974 223 0.036
negative regulation of nucleic acid templated transcription GO:1903507 240 0.035
cytoplasmic transport GO:0016482 130 0.035
regulation of cell death GO:0010941 173 0.034
Fly
regulation of cell cycle process GO:0010564 181 0.033
meiotic cell cycle GO:0051321 171 0.033
macromolecular complex assembly GO:0065003 256 0.032
Fly
oocyte differentiation GO:0009994 145 0.031
negative regulation of developmental process GO:0051093 201 0.031
cellular macromolecule localization GO:0070727 220 0.030
response to organic substance GO:0010033 284 0.028
protein modification process GO:0036211 438 0.028
Fly
regionalization GO:0003002 416 0.028
mrna splicing via spliceosome GO:0000398 73 0.028
regulation of phosphate metabolic process GO:0019220 210 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
nuclear division GO:0000280 332 0.027
regulation of catabolic process GO:0009894 170 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
apoptotic process GO:0006915 159 0.026
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.026
regulation of programmed cell death GO:0043067 152 0.025
Fly
imaginal disc derived appendage development GO:0048737 399 0.025
wing disc morphogenesis GO:0007472 344 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
spinal cord development GO:0021510 1 0.023
regulation of catalytic activity GO:0050790 185 0.023
nuclear transport GO:0051169 72 0.023
peptidyl amino acid modification GO:0018193 105 0.023
Fly
single organism catabolic process GO:0044712 228 0.023
regulation of organelle organization GO:0033043 196 0.023
Fly
intracellular signal transduction GO:0035556 300 0.022
regulation of molecular function GO:0065009 217 0.022
oxoacid metabolic process GO:0043436 103 0.022
phosphorylation GO:0016310 294 0.022
intracellular transport GO:0046907 228 0.021
regulation of dna templated transcription elongation GO:0032784 17 0.021
ras protein signal transduction GO:0007265 88 0.021
dna templated transcription elongation GO:0006354 18 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
mitotic cell cycle checkpoint GO:0007093 88 0.020
regulation of hydrolase activity GO:0051336 97 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
negative regulation of cell death GO:0060548 81 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
cell cycle checkpoint GO:0000075 95 0.019
histone methylation GO:0016571 40 0.019
Fly
atp dependent chromatin remodeling GO:0043044 22 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
Fly
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
aromatic compound catabolic process GO:0019439 166 0.018
peptidyl lysine acetylation GO:0018394 39 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
mitotic dna damage checkpoint GO:0044773 74 0.018
camera type eye development GO:0043010 4 0.017
positive regulation of molecular function GO:0044093 136 0.017
rna localization GO:0006403 115 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
heterocycle catabolic process GO:0046700 166 0.017
peptidyl lysine methylation GO:0018022 16 0.017
Fly
cellular protein localization GO:0034613 160 0.017
response to abiotic stimulus GO:0009628 341 0.017
regulation of mitotic cell cycle GO:0007346 190 0.016
appendage morphogenesis GO:0035107 397 0.016
macromolecule catabolic process GO:0009057 161 0.016
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
organic substance transport GO:0071702 257 0.015
regulation of chromatin modification GO:1903308 28 0.015
Fly
actin cytoskeleton organization GO:0030036 206 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
Fly
single organism behavior GO:0044708 391 0.015
regulation of histone modification GO:0031056 20 0.015
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.014
regulation of cell division GO:0051302 72 0.014
histone acetylation GO:0016573 38 0.014
internal peptidyl lysine acetylation GO:0018393 38 0.014
embryonic pattern specification GO:0009880 174 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
cell motility GO:0048870 251 0.014
nucleosome organization GO:0034728 59 0.013
protein dna complex subunit organization GO:0071824 86 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
mrna catabolic process GO:0006402 33 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
positive regulation of organelle organization GO:0010638 65 0.012
Fly
cellular macromolecular complex assembly GO:0034622 153 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
Fly
protein localization to nucleus GO:0034504 55 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
rna processing GO:0006396 147 0.012
internal protein amino acid acetylation GO:0006475 38 0.012
single organism cellular localization GO:1902580 180 0.012
cell division GO:0051301 248 0.012
cell proliferation GO:0008283 299 0.012
dna integrity checkpoint GO:0031570 81 0.011
amine metabolic process GO:0009308 12 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
protein phosphorylation GO:0006468 169 0.011
negative regulation of molecular function GO:0044092 51 0.011
regulation of immune system process GO:0002682 176 0.011
regulation of protein modification process GO:0031399 112 0.011
Fly
covalent chromatin modification GO:0016569 106 0.011
Fly
organic acid metabolic process GO:0006082 103 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
protein localization GO:0008104 284 0.011
nucleobase containing compound transport GO:0015931 56 0.011
cellular amine metabolic process GO:0044106 12 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
nitrogen compound transport GO:0071705 85 0.011
mitotic spindle organization GO:0007052 220 0.011
mitotic cell cycle phase transition GO:0044772 138 0.010
nuclear export GO:0051168 24 0.010
microtubule organizing center organization GO:0031023 168 0.010
dna metabolic process GO:0006259 227 0.010
Fly
negative regulation of response to stimulus GO:0048585 258 0.010
response to oxygen containing compound GO:1901700 200 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
positive regulation of protein modification process GO:0031401 58 0.010
Fly
regulation of phosphorylation GO:0042325 147 0.010
neurological system process GO:0050877 358 0.010
endomembrane system organization GO:0010256 119 0.010
protein localization to organelle GO:0033365 82 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
eye development GO:0001654 323 0.010

HP1c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.013