Drosophila melanogaster

6 known processes

Hmt-1 (Dmel_CG4225)

Heavy metal tolerance factor 1

(Aliases: hmt-1,EP(3)3387,Dmel\CG4225,CG4225)

Hmt-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 381 0.065
organonitrogen compound metabolic process GO:1901564 318 0.060
Human
small molecule metabolic process GO:0044281 305 0.057
Human
organophosphate metabolic process GO:0019637 195 0.057
Human
ion transport GO:0006811 145 0.057
cellular protein modification process GO:0006464 438 0.049
cation transmembrane transport GO:0098655 88 0.047
catabolic process GO:0009056 409 0.046
Human
single organism catabolic process GO:0044712 228 0.045
Human
carbohydrate derivative metabolic process GO:1901135 217 0.042
Human
cellular catabolic process GO:0044248 372 0.040
Human
lipid metabolic process GO:0006629 121 0.039
organic substance catabolic process GO:1901575 308 0.037
Human
organic substance transport GO:0071702 257 0.037
Human
ribonucleotide metabolic process GO:0009259 145 0.036
Human
homeostatic process GO:0042592 199 0.035
response to abiotic stimulus GO:0009628 341 0.035
transmembrane transport GO:0055085 139 0.034
Human
glycosyl compound catabolic process GO:1901658 112 0.034
Human
regulation of localization GO:0032879 275 0.033
organonitrogen compound biosynthetic process GO:1901566 117 0.031
Human
cation transport GO:0006812 110 0.029
purine ribonucleoside metabolic process GO:0046128 127 0.028
Human
spermatogenesis GO:0007283 200 0.028
nuclear division GO:0000280 332 0.028
carboxylic acid metabolic process GO:0019752 92 0.028
protein modification process GO:0036211 438 0.028
intracellular transport GO:0046907 228 0.027
metal ion transport GO:0030001 74 0.027
aromatic compound catabolic process GO:0019439 166 0.027
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.027
Human
phagocytosis GO:0006909 215 0.026
macromolecular complex assembly GO:0065003 256 0.026
ion transmembrane transport GO:0034220 122 0.026
endocytosis GO:0006897 310 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
compound eye development GO:0048749 307 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.024
Human
establishment of localization in cell GO:0051649 402 0.024
organonitrogen compound catabolic process GO:1901565 128 0.024
Human
regulation of cellular catabolic process GO:0031329 157 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
Human
response to oxygen containing compound GO:1901700 200 0.023
single organism membrane organization GO:0044802 93 0.023
glycerophospholipid metabolic process GO:0006650 23 0.023
connective tissue development GO:0061448 3 0.023
single organism intracellular transport GO:1902582 207 0.023
glycerolipid metabolic process GO:0046486 34 0.023
organophosphate catabolic process GO:0046434 112 0.022
Human
oxoacid metabolic process GO:0043436 103 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
cellular lipid metabolic process GO:0044255 83 0.022
protein modification by small protein conjugation or removal GO:0070647 106 0.022
organelle fusion GO:0048284 46 0.022
mitotic nuclear division GO:0007067 213 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
Human
positive regulation of molecular function GO:0044093 136 0.022
regulation of transport GO:0051049 181 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
Human
regulation of catabolic process GO:0009894 170 0.021
regulation of cell cycle GO:0051726 291 0.021
single organism biosynthetic process GO:0044711 206 0.021
purine containing compound catabolic process GO:0072523 112 0.021
Human
appendage morphogenesis GO:0035107 397 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.021
Human
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
Human
membrane organization GO:0061024 112 0.020
purine containing compound metabolic process GO:0072521 155 0.020
Human
response to other organism GO:0051707 293 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
Human
regulation of phosphorus metabolic process GO:0051174 210 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.020
Human
ribonucleoside metabolic process GO:0009119 127 0.020
Human
protein complex assembly GO:0006461 200 0.020
protein modification by small protein conjugation GO:0032446 79 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
Human
cell division GO:0051301 248 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
Human
cellular response to dna damage stimulus GO:0006974 223 0.019
negative regulation of signaling GO:0023057 219 0.019
regulation of programmed cell death GO:0043067 152 0.019
regulation of catalytic activity GO:0050790 185 0.019
response to external biotic stimulus GO:0043207 293 0.018
proteolysis GO:0006508 192 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
Human
ribonucleoside catabolic process GO:0042454 112 0.018
Human
developmental growth GO:0048589 280 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
organelle fission GO:0048285 340 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
cation homeostasis GO:0055080 51 0.018
death GO:0016265 284 0.018
intracellular signal transduction GO:0035556 300 0.018
protein maturation GO:0051604 71 0.018
anion transport GO:0006820 41 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
Human
sodium dependent phosphate transport GO:0044341 2 0.017
regulation of small gtpase mediated signal transduction GO:0051056 93 0.017
detection of stimulus GO:0051606 156 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
Human
cellular homeostasis GO:0019725 80 0.017
inorganic cation transmembrane transport GO:0098662 61 0.017
inorganic ion transmembrane transport GO:0098660 73 0.017
protein complex biogenesis GO:0070271 201 0.017
organic acid metabolic process GO:0006082 103 0.017
purine nucleoside catabolic process GO:0006152 112 0.017
Human
regulation of molecular function GO:0065009 217 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
Human
purine nucleoside metabolic process GO:0042278 127 0.016
Human
negative regulation of signal transduction GO:0009968 206 0.016
translation GO:0006412 69 0.016
lipid biosynthetic process GO:0008610 46 0.016
nucleotide metabolic process GO:0009117 161 0.016
Human
cellular macromolecule localization GO:0070727 220 0.016
protein localization GO:0008104 284 0.016
response to lipopolysaccharide GO:0032496 4 0.016
nucleotide catabolic process GO:0009166 109 0.016
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
Human
programmed cell death GO:0012501 257 0.015
atp metabolic process GO:0046034 49 0.015
Human
modification dependent protein catabolic process GO:0019941 78 0.015
nucleoside metabolic process GO:0009116 127 0.015
Human
cell death GO:0008219 279 0.015
regionalization GO:0003002 416 0.015
ras protein signal transduction GO:0007265 88 0.015
l amino acid import GO:0043092 2 0.015
ion homeostasis GO:0050801 55 0.015
wing disc morphogenesis GO:0007472 344 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
response to bacterium GO:0009617 198 0.014
protein catabolic process GO:0030163 101 0.014
response to organic substance GO:0010033 284 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
Human
cellular macromolecule catabolic process GO:0044265 136 0.014
heterocycle catabolic process GO:0046700 166 0.014
Human
chromosome organization GO:0051276 360 0.014
biological adhesion GO:0022610 138 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
defense response to bacterium GO:0042742 178 0.014
macromolecule catabolic process GO:0009057 161 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
Human
regulation of phosphate metabolic process GO:0019220 210 0.014
dna metabolic process GO:0006259 227 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
positive regulation of response to stimulus GO:0048584 323 0.013
response to biotic stimulus GO:0009607 294 0.013
regulation of cell death GO:0010941 173 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
cell migration GO:0016477 238 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
Human
purine ribonucleotide metabolic process GO:0009150 145 0.013
Human
phosphorylation GO:0016310 294 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
Human
nitrogen compound transport GO:0071705 85 0.013
Human
regulation of ras protein signal transduction GO:0046578 93 0.013
positive regulation of signal transduction GO:0009967 223 0.013
growth GO:0040007 359 0.013
detection of chemical stimulus GO:0009593 93 0.013
appendage development GO:0048736 401 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.012
membrane fusion GO:0061025 42 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
male gamete generation GO:0048232 201 0.012
cellular protein catabolic process GO:0044257 83 0.012
negative regulation of cell communication GO:0010648 223 0.012
positive regulation of lipid storage GO:0010884 4 0.012
endomembrane system organization GO:0010256 119 0.012
regulation of protein metabolic process GO:0051246 256 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
response to alcohol GO:0097305 95 0.012
defense response to other organism GO:0098542 225 0.012
forebrain development GO:0030900 2 0.012
metal ion homeostasis GO:0055065 44 0.012
cytoplasmic transport GO:0016482 130 0.012
compound eye morphogenesis GO:0001745 249 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
positive regulation of cell communication GO:0010647 250 0.012
chemical homeostasis GO:0048878 92 0.012
positive regulation of catabolic process GO:0009896 105 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.011
response to nutrient levels GO:0031667 114 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
protein transport GO:0015031 155 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
monocarboxylic acid transport GO:0015718 3 0.011
gland development GO:0048732 191 0.011
protein ubiquitination GO:0016567 70 0.011
phosphate ion transport GO:0006817 4 0.011
positive regulation of signaling GO:0023056 243 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
response to radiation GO:0009314 155 0.011
regulation of growth GO:0040008 233 0.011
synaptic transmission GO:0007268 288 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
maintenance of location GO:0051235 73 0.011
androgen metabolic process GO:0008209 1 0.011
regulation of organelle organization GO:0033043 196 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
body morphogenesis GO:0010171 2 0.010
nucleoside catabolic process GO:0009164 112 0.010
Human
establishment of protein localization GO:0045184 163 0.010
oocyte construction GO:0007308 112 0.010
response to organic cyclic compound GO:0014070 89 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
cellular amine metabolic process GO:0044106 12 0.010
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.010
regulation of cellular localization GO:0060341 136 0.010
ethanolamine containing compound metabolic process GO:0042439 4 0.010
regulation of anatomical structure size GO:0090066 163 0.010

Hmt-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.078
nervous system disease DOID:863 0 0.037
central nervous system disease DOID:331 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
disease of metabolism DOID:0014667 0 0.011
neurodegenerative disease DOID:1289 0 0.011
inherited metabolic disorder DOID:655 0 0.010
eye disease DOID:5614 0 0.010