Drosophila melanogaster

25 known processes

Spat (Dmel_CG3926)

Serine pyruvate aminotransferase

(Aliases: spa,Dm-Spat,CG3926,spat,Dmel\CG3926)

Spat biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling involved in cell fate commitment GO:0045168 210 0.118
cell proliferation GO:0008283 299 0.087
lateral inhibition GO:0046331 206 0.078
catabolic process GO:0009056 409 0.076
innate immune response GO:0045087 144 0.074
organonitrogen compound metabolic process GO:1901564 318 0.069
Yeast Rat
male gamete generation GO:0048232 201 0.067
organic substance catabolic process GO:1901575 308 0.060
neurological system process GO:0050877 358 0.058
response to external biotic stimulus GO:0043207 293 0.054
organic substance transport GO:0071702 257 0.054
regulation of behavior GO:0050795 75 0.053
nucleus organization GO:0006997 45 0.051
small molecule metabolic process GO:0044281 305 0.050
nucleobase containing small molecule metabolic process GO:0055086 174 0.040
tissue death GO:0016271 102 0.039
cellular catabolic process GO:0044248 372 0.037
response to glucose GO:0009749 2 0.037
kidney development GO:0001822 3 0.037
organic acid metabolic process GO:0006082 103 0.036
spermatogenesis GO:0007283 200 0.036
immune response GO:0006955 246 0.036
peptide metabolic process GO:0006518 80 0.033
wing disc morphogenesis GO:0007472 344 0.033
response to biotic stimulus GO:0009607 294 0.033
response to other organism GO:0051707 293 0.032
proteolysis GO:0006508 192 0.030
response to organic substance GO:0010033 284 0.030
Rat
histolysis GO:0007559 102 0.029
defense response to other organism GO:0098542 225 0.029
immune system process GO:0002376 347 0.029
defense response GO:0006952 300 0.028
cellularization GO:0007349 90 0.028
regulation of heart contraction GO:0008016 21 0.028
heart process GO:0003015 37 0.027
salivary gland morphogenesis GO:0007435 145 0.026
purine containing compound metabolic process GO:0072521 155 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
cell death GO:0008219 279 0.026
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
neurotransmitter catabolic process GO:0042135 1 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
s adenosylmethionine cycle GO:0033353 3 0.025
regulation of multi organism process GO:0043900 131 0.025
rhythmic behavior GO:0007622 76 0.024
salivary gland development GO:0007431 162 0.024
organonitrogen compound catabolic process GO:1901565 128 0.024
gland development GO:0048732 191 0.024
response to abiotic stimulus GO:0009628 341 0.023
ribonucleoside metabolic process GO:0009119 127 0.023
negative regulation of gene expression GO:0010629 387 0.023
circadian behavior GO:0048512 76 0.023
purine nucleoside metabolic process GO:0042278 127 0.023
spermatid development GO:0007286 98 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
biological adhesion GO:0022610 138 0.023
salivary gland histolysis GO:0035070 88 0.022
appendage morphogenesis GO:0035107 397 0.022
ion transport GO:0006811 145 0.022
exocrine system development GO:0035272 162 0.022
positive regulation of biosynthetic process GO:0009891 316 0.021
sperm individualization GO:0007291 48 0.021
salivary gland cell autophagic cell death GO:0035071 83 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
cell migration GO:0016477 238 0.020
cellular protein modification process GO:0006464 438 0.020
epithelial cell development GO:0002064 274 0.020
protein modification process GO:0036211 438 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
regulation of circadian rhythm GO:0042752 49 0.020
localization of cell GO:0051674 257 0.019
cellular amide metabolic process GO:0043603 80 0.019
fat soluble vitamin metabolic process GO:0006775 1 0.019
intracellular transport GO:0046907 228 0.019
appendage development GO:0048736 401 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
single organism catabolic process GO:0044712 228 0.019
monocarboxylic acid transport GO:0015718 3 0.019
death GO:0016265 284 0.019
homeostatic process GO:0042592 199 0.019
multicellular organismal reproductive behavior GO:0033057 110 0.018
response to monosaccharide GO:0034284 4 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
programmed cell death GO:0012501 257 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
Yeast Rat
synaptic transmission GO:0007268 288 0.018
circulatory system process GO:0003013 37 0.018
gland morphogenesis GO:0022612 145 0.018
heart morphogenesis GO:0003007 32 0.018
regulation of heart rate GO:0002027 11 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
single organism behavior GO:0044708 391 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
heart contraction GO:0060047 26 0.018
secretion GO:0046903 109 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
wound healing GO:0042060 75 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
nucleoside metabolic process GO:0009116 127 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
autophagic cell death GO:0048102 83 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
rhythmic process GO:0048511 106 0.017
cellular amine metabolic process GO:0044106 12 0.017
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
water homeostasis GO:0030104 3 0.016
cellular response to extracellular stimulus GO:0031668 64 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
Yeast Rat
cell motility GO:0048870 251 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
hormone catabolic process GO:0042447 3 0.016
regulation of circadian sleep wake cycle GO:0042749 25 0.016
regionalization GO:0003002 416 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
amine metabolic process GO:0009308 12 0.015
macromolecule catabolic process GO:0009057 161 0.015
nucleotide metabolic process GO:0009117 161 0.015
establishment of localization in cell GO:0051649 402 0.015
urogenital system development GO:0001655 72 0.015
macromolecular complex assembly GO:0065003 256 0.015
oxoacid metabolic process GO:0043436 103 0.015
developmental programmed cell death GO:0010623 138 0.014
negative regulation of signaling GO:0023057 219 0.014
epithelial cell differentiation GO:0030855 322 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
chromosome segregation GO:0007059 157 0.014
telencephalon development GO:0021537 2 0.014
response to virus GO:0009615 28 0.014
acid secretion GO:0046717 1 0.014
transmembrane transport GO:0055085 139 0.014
positive regulation of gene expression GO:0010628 290 0.014
negative regulation of cell communication GO:0010648 223 0.014
ethanolamine containing compound metabolic process GO:0042439 4 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
positive regulation of cell communication GO:0010647 250 0.014
intracellular signal transduction GO:0035556 300 0.014
organelle fission GO:0048285 340 0.014
sleep GO:0030431 49 0.013
tissue migration GO:0090130 155 0.013
single organism intracellular transport GO:1902582 207 0.013
developmental growth GO:0048589 280 0.013
negative regulation of signal transduction GO:0009968 206 0.013
spermatid differentiation GO:0048515 114 0.013
connective tissue development GO:0061448 3 0.013
compound eye development GO:0048749 307 0.013
response to endogenous stimulus GO:0009719 119 0.013
Rat
organophosphate metabolic process GO:0019637 195 0.013
compound eye morphogenesis GO:0001745 249 0.013
establishment of protein localization GO:0045184 163 0.013
regulation of localization GO:0032879 275 0.013
dna metabolic process GO:0006259 227 0.013
spindle organization GO:0007051 253 0.013
chromosome organization GO:0051276 360 0.013
immune effector process GO:0002252 98 0.013
cellular response to chemical stimulus GO:0070887 199 0.012
body morphogenesis GO:0010171 2 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
response to bacterium GO:0009617 198 0.012
mating behavior GO:0007617 106 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
epithelial cell migration GO:0010631 148 0.012
regulation of immune system process GO:0002682 176 0.012
nitrogen compound transport GO:0071705 85 0.012
secondary metabolic process GO:0019748 75 0.012
hormone metabolic process GO:0042445 33 0.012
defense response to bacterium GO:0042742 178 0.012
chromatin modification GO:0016568 147 0.012
positive regulation of cell motility GO:2000147 3 0.012
insecticide catabolic process GO:0046701 1 0.012
humoral immune response GO:0006959 117 0.012
circadian sleep wake cycle sleep GO:0050802 23 0.012
organelle assembly GO:0070925 198 0.012
multi organism reproductive behavior GO:0044705 121 0.012
regulation of anatomical structure size GO:0090066 163 0.012
ovarian follicle cell migration GO:0007297 121 0.012
nuclear division GO:0000280 332 0.012
single organism biosynthetic process GO:0044711 206 0.012
Yeast Rat
regulation of molecular function GO:0065009 217 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
positive regulation of signal transduction GO:0009967 223 0.011
regulation of cell death GO:0010941 173 0.011
protein complex biogenesis GO:0070271 201 0.011
protein localization GO:0008104 284 0.011
regulation of immune response GO:0050776 118 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
neuron projection guidance GO:0097485 241 0.011
eye development GO:0001654 323 0.011
mating GO:0007618 120 0.011
renal system development GO:0072001 72 0.011
response to oxygen containing compound GO:1901700 200 0.011
Rat
circadian sleep wake cycle process GO:0022410 24 0.011
androgen metabolic process GO:0008209 1 0.011
production of molecular mediator of immune response GO:0002440 46 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
developmental maturation GO:0021700 172 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
lipid metabolic process GO:0006629 121 0.011
cellular ketone metabolic process GO:0042180 24 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
cellular response to external stimulus GO:0071496 66 0.011
reproductive behavior GO:0019098 122 0.011
chemotaxis GO:0006935 249 0.011
ras protein signal transduction GO:0007265 88 0.011
phosphorylation GO:0016310 294 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
blood circulation GO:0008015 26 0.010
mapk cascade GO:0000165 107 0.010
circadian sleep wake cycle GO:0042745 28 0.010
male mating behavior GO:0060179 70 0.010
anatomical structure homeostasis GO:0060249 97 0.010
phagocytosis GO:0006909 215 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
positive regulation of response to stimulus GO:0048584 323 0.010
cardiovascular system development GO:0072358 82 0.010
regulation of antimicrobial humoral response GO:0002759 50 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
axonogenesis GO:0007409 290 0.010
epithelium migration GO:0090132 148 0.010
cellular response to starvation GO:0009267 61 0.010

Spat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.037
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.014
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
cardiovascular system disease DOID:1287 0 0.012
disease of metabolism DOID:0014667 0 0.010
acquired metabolic disease DOID:0060158 0 0.010