Drosophila melanogaster

40 known processes

HmgD (Dmel_CG17950)

High mobility group protein D

(Aliases: Dm-HMG-D100,hmg-D,dHMG-D,HMGD,CG17950,HMG-D,anon-EST:Liang-1.9,clone 1.9,Hmg-D,Dmel\CG17950,HMG-D100,HMG D)

HmgD biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin silencing GO:0006342 76 0.815
negative regulation of gene expression epigenetic GO:0045814 77 0.730
negative regulation of cellular biosynthetic process GO:0031327 277 0.646
protein complex biogenesis GO:0070271 201 0.550
regulation of gene expression epigenetic GO:0040029 128 0.511
macromolecular complex assembly GO:0065003 256 0.434
negative regulation of rna metabolic process GO:0051253 251 0.377
negative regulation of gene expression GO:0010629 387 0.348
negative regulation of rna biosynthetic process GO:1902679 240 0.343
mrna metabolic process GO:0016071 124 0.334
mitotic spindle organization GO:0007052 220 0.332
chromatin organization GO:0006325 207 0.299
gene silencing GO:0016458 138 0.292
cellular macromolecular complex assembly GO:0034622 153 0.291
chromosome organization GO:0051276 360 0.276
dna metabolic process GO:0006259 227 0.270
dna conformation change GO:0071103 105 0.264
protein complex assembly GO:0006461 200 0.245
organelle fission GO:0048285 340 0.240
single organism behavior GO:0044708 391 0.232
mitotic cell cycle embryonic GO:0045448 38 0.230
response to abiotic stimulus GO:0009628 341 0.215
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.209
mitotic nuclear division GO:0007067 213 0.195
mitotic cell cycle phase transition GO:0044772 138 0.192
regulation of gene silencing GO:0060968 63 0.185
dna packaging GO:0006323 91 0.166
cellular protein complex assembly GO:0043623 71 0.153
mrna processing GO:0006397 104 0.147
chromatin assembly GO:0031497 48 0.144
heterochromatin organization GO:0070828 25 0.137
dna repair GO:0006281 54 0.135
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.133
tissue morphogenesis GO:0048729 297 0.132
organonitrogen compound metabolic process GO:1901564 318 0.132
regulation of cytoskeleton organization GO:0051493 89 0.129
negative regulation of cellular metabolic process GO:0031324 382 0.124
regulation of multicellular organismal development GO:2000026 414 0.122
regulation of mitotic cell cycle GO:0007346 190 0.118
regulation of organelle organization GO:0033043 196 0.117
protein polymerization GO:0051258 42 0.115
rna processing GO:0006396 147 0.115
actin nucleation GO:0045010 8 0.115
intracellular transport GO:0046907 228 0.114
cellular response to abiotic stimulus GO:0071214 58 0.112
positive regulation of protein metabolic process GO:0051247 128 0.110
response to temperature stimulus GO:0009266 106 0.104
regulation of cellular component biogenesis GO:0044087 201 0.103
negative regulation of nucleic acid templated transcription GO:1903507 240 0.102
negative regulation of biosynthetic process GO:0009890 277 0.100
embryo development ending in birth or egg hatching GO:0009792 152 0.100
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.096
cell cycle phase transition GO:0044770 140 0.093
oxoacid metabolic process GO:0043436 103 0.089
protein modification process GO:0036211 438 0.088
actin filament organization GO:0007015 126 0.087
cellular response to dna damage stimulus GO:0006974 223 0.084
spindle organization GO:0007051 253 0.083
mitotic sister chromatid segregation GO:0000070 87 0.083
rna splicing via transesterification reactions GO:0000375 73 0.082
learning GO:0007612 75 0.079
gland development GO:0048732 191 0.078
positive regulation of proteolysis GO:0045862 52 0.076
negative regulation of cellular component organization GO:0051129 108 0.076
organic acid metabolic process GO:0006082 103 0.071
positive regulation of developmental process GO:0051094 143 0.070
positive regulation of macromolecule metabolic process GO:0010604 405 0.068
regulation of protein complex assembly GO:0043254 42 0.068
nucleobase containing small molecule metabolic process GO:0055086 174 0.067
regulation of chromatin silencing GO:0031935 36 0.067
muscle organ development GO:0007517 127 0.066
organic substance catabolic process GO:1901575 308 0.062
adult behavior GO:0030534 137 0.062
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.061
regulation of protein metabolic process GO:0051246 256 0.060
sensory organ morphogenesis GO:0090596 260 0.059
sister chromatid segregation GO:0000819 92 0.058
regulation of cell cycle process GO:0010564 181 0.057
alternative mrna splicing via spliceosome GO:0000380 60 0.057
multicellular organismal reproductive behavior GO:0033057 110 0.056
chromatin assembly or disassembly GO:0006333 52 0.056
taxis GO:0042330 304 0.056
nucleoside phosphate metabolic process GO:0006753 162 0.055
carboxylic acid metabolic process GO:0019752 92 0.055
mrna splicing via spliceosome GO:0000398 73 0.055
histolysis GO:0007559 102 0.054
regulation of mrna processing GO:0050684 71 0.053
cellular response to sterol depletion GO:0071501 3 0.051
positive regulation of catalytic activity GO:0043085 118 0.050
g1 s transition of mitotic cell cycle GO:0000082 31 0.050
gland morphogenesis GO:0022612 145 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.049
salivary gland morphogenesis GO:0007435 145 0.049
positive regulation of biosynthetic process GO:0009891 316 0.047
regulation of transport GO:0051049 181 0.047
protein localization GO:0008104 284 0.046
macromolecule methylation GO:0043414 45 0.044
regulation of cell cycle GO:0051726 291 0.042
nuclear division GO:0000280 332 0.041
regulation of mrna splicing via spliceosome GO:0048024 64 0.041
regulation of mitotic cell cycle embryonic GO:0009794 11 0.040
cellular amino acid metabolic process GO:0006520 61 0.039
feeding behavior GO:0007631 50 0.038
positive regulation of cellular component organization GO:0051130 156 0.038
positive regulation of cellular protein metabolic process GO:0032270 118 0.037
locomotory behavior GO:0007626 176 0.037
autophagic cell death GO:0048102 83 0.036
nitrogen compound transport GO:0071705 85 0.036
arp2 3 complex mediated actin nucleation GO:0034314 3 0.036
guanosine containing compound catabolic process GO:1901069 74 0.036
rna splicing GO:0008380 83 0.036
regulation of intracellular signal transduction GO:1902531 236 0.036
regulation of mitotic cell cycle phase transition GO:1901990 130 0.036
actin filament polymerization GO:0030041 27 0.035
muscle structure development GO:0061061 224 0.035
protein complex localization GO:0031503 4 0.034
small molecule metabolic process GO:0044281 305 0.034
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.034
organic cyclic compound catabolic process GO:1901361 168 0.034
microtubule organizing center organization GO:0031023 168 0.034
wing disc dorsal ventral pattern formation GO:0048190 47 0.033
methylation GO:0032259 47 0.033
nucleoside triphosphate metabolic process GO:0009141 120 0.033
protein methylation GO:0006479 43 0.033
regulation of actin cytoskeleton organization GO:0032956 42 0.033
salivary gland cell autophagic cell death GO:0035071 83 0.033
chromatin modification GO:0016568 147 0.032
compound eye development GO:0048749 307 0.032
wing disc pattern formation GO:0035222 66 0.032
olfactory behavior GO:0042048 97 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.031
posttranscriptional gene silencing GO:0016441 46 0.031
regulation of cellular protein metabolic process GO:0032268 243 0.031
spindle assembly GO:0051225 80 0.031
regulation of apoptotic process GO:0042981 130 0.030
lateral inhibition GO:0046331 206 0.030
ribose phosphate metabolic process GO:0019693 145 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.029
cell division GO:0051301 248 0.029
intracellular signal transduction GO:0035556 300 0.029
cellular protein modification process GO:0006464 438 0.029
meiotic cell cycle GO:0051321 171 0.028
nucleotide metabolic process GO:0009117 161 0.028
eye morphogenesis GO:0048592 260 0.028
regulation of embryonic development GO:0045995 68 0.028
response to organic substance GO:0010033 284 0.028
organic substance transport GO:0071702 257 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.027
regulation of cellular amine metabolic process GO:0033238 3 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
positive regulation of actin filament polymerization GO:0030838 11 0.026
regionalization GO:0003002 416 0.026
regulation of hydrolase activity GO:0051336 97 0.026
negative regulation of response to external stimulus GO:0032102 22 0.025
negative regulation of transcription dna templated GO:0045892 237 0.025
salivary gland development GO:0007431 162 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.024
eye development GO:0001654 323 0.024
reproductive structure development GO:0048608 74 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.024
histone methylation GO:0016571 40 0.024
mesenchymal cell differentiation GO:0048762 1 0.023
positive regulation of organelle organization GO:0010638 65 0.023
negative regulation of cell cycle GO:0045786 116 0.023
regulation of synapse assembly GO:0051963 94 0.023
regulation of actin filament based process GO:0032970 42 0.023
neuron migration GO:0001764 5 0.023
actin cytoskeleton organization GO:0030036 206 0.023
regulation of catalytic activity GO:0050790 185 0.023
dorsal ventral pattern formation GO:0009953 133 0.023
positive regulation of gene expression GO:0010628 290 0.022
transcription from rna polymerase ii promoter GO:0006366 368 0.022
mesenchymal cell development GO:0014031 1 0.022
protein alkylation GO:0008213 43 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
regulation of cellular response to stress GO:0080135 89 0.022
photoreceptor cell differentiation GO:0046530 170 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.021
regulation of ras protein signal transduction GO:0046578 93 0.021
histone lysine methylation GO:0034968 32 0.021
establishment of localization in cell GO:0051649 402 0.021
establishment of mitotic spindle localization GO:0040001 17 0.021
response to nitrogen compound GO:1901698 90 0.020
regulation of response to stress GO:0080134 200 0.020
rna localization GO:0006403 115 0.020
salivary gland histolysis GO:0035070 88 0.020
cellular ketone metabolic process GO:0042180 24 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
response to extracellular stimulus GO:0009991 116 0.019
telencephalon development GO:0021537 2 0.019
apoptotic process GO:0006915 159 0.019
regulation of cellular localization GO:0060341 136 0.019
cell cycle g1 s phase transition GO:0044843 31 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.019
regulation of actin filament polymerization GO:0030833 25 0.019
golgi organization GO:0007030 66 0.019
glutamine metabolic process GO:0006541 4 0.019
central nervous system development GO:0007417 201 0.019
ribonucleotide metabolic process GO:0009259 145 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.018
reproductive system development GO:0061458 74 0.018
tissue death GO:0016271 102 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
regulation of mrna metabolic process GO:1903311 72 0.018
death GO:0016265 284 0.018
positive regulation of developmental growth GO:0048639 62 0.018
nucleotide catabolic process GO:0009166 109 0.018
aromatic compound catabolic process GO:0019439 166 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
response to organic cyclic compound GO:0014070 89 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
cilium morphogenesis GO:0060271 39 0.017
ncrna metabolic process GO:0034660 43 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.017
positive regulation of protein complex assembly GO:0031334 22 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
regulation of cell development GO:0060284 215 0.017
nucleosome assembly GO:0006334 35 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
single organism intracellular transport GO:1902582 207 0.016
centrosome organization GO:0051297 163 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
camera type eye development GO:0043010 4 0.016
regulation of localization GO:0032879 275 0.016
positive regulation of cell development GO:0010720 61 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
developmental programmed cell death GO:0010623 138 0.016
regulation of actin polymerization or depolymerization GO:0008064 27 0.016
retina development in camera type eye GO:0060041 4 0.016
body morphogenesis GO:0010171 2 0.016
regulation of proteasomal protein catabolic process GO:0061136 39 0.016
purine nucleoside metabolic process GO:0042278 127 0.015
dephosphorylation GO:0016311 51 0.015
cell death GO:0008219 279 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
response to radiation GO:0009314 155 0.015
negative regulation of signaling GO:0023057 219 0.015
positive regulation of signaling GO:0023056 243 0.015
positive regulation of protein modification process GO:0031401 58 0.015
neuron projection guidance GO:0097485 241 0.015
catabolic process GO:0009056 409 0.014
heterocycle catabolic process GO:0046700 166 0.014
brain development GO:0007420 120 0.014
regulation of programmed cell death GO:0043067 152 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
larval behavior GO:0030537 42 0.014
phosphorylation GO:0016310 294 0.014
sex differentiation GO:0007548 81 0.014
cellular response to organic substance GO:0071310 132 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
larval locomotory behavior GO:0008345 27 0.013
wnt signaling pathway GO:0016055 98 0.013
regulation of nervous system development GO:0051960 248 0.013
regulation of protein polymerization GO:0032271 28 0.013
epithelial cell differentiation GO:0030855 322 0.013
protein dna complex assembly GO:0065004 63 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
regulation of chromosome organization GO:0033044 64 0.013
peptidyl lysine dimethylation GO:0018027 3 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
regulation of multicellular organism growth GO:0040014 40 0.013
amine metabolic process GO:0009308 12 0.013
dendrite development GO:0016358 204 0.013
multi organism reproductive behavior GO:0044705 121 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
establishment of rna localization GO:0051236 47 0.013
actin polymerization or depolymerization GO:0008154 31 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
negative regulation of organelle organization GO:0010639 56 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
chromatin remodeling GO:0006338 72 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
regulation of glial cell differentiation GO:0045685 1 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
negative regulation of developmental process GO:0051093 201 0.012
positive regulation of signal transduction GO:0009967 223 0.012
positive regulation of cytoskeleton organization GO:0051495 21 0.012
protein phosphorylation GO:0006468 169 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
regulation of protein catabolic process GO:0042176 55 0.012
nucleic acid transport GO:0050657 46 0.011
covalent chromatin modification GO:0016569 106 0.011
response to oxygen levels GO:0070482 59 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
genitalia development GO:0048806 26 0.011
regulation of dna metabolic process GO:0051052 34 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
establishment of spindle localization GO:0051293 22 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
respiratory system development GO:0060541 213 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
head development GO:0060322 135 0.011
recombinational repair GO:0000725 13 0.011
reactive oxygen species biosynthetic process GO:1903409 0 0.010
spindle assembly involved in mitosis GO:0090307 50 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
endocytosis GO:0006897 310 0.010
response to nutrient levels GO:0031667 114 0.010
protein modification by small protein conjugation GO:0032446 79 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
reproductive behavior GO:0019098 122 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010

HmgD disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.028
disease of anatomical entity DOID:7 0 0.025
motor neuron disease DOID:231 0 0.023
central nervous system disease DOID:331 0 0.023
neurodegenerative disease DOID:1289 0 0.023
nervous system disease DOID:863 0 0.023
cancer DOID:162 0 0.010
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010