Drosophila melanogaster

15 known processes

Droj2 (Dmel_CG8863)

DnaJ-like-2

(Aliases: CG8863,anon-WO0118547.404,Dmel\CG8863)

Droj2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.657
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.592
Yeast
positive regulation of cellular biosynthetic process GO:0031328 316 0.386
transcription from rna polymerase ii promoter GO:0006366 368 0.323
catabolic process GO:0009056 409 0.277
Yeast
cellular catabolic process GO:0044248 372 0.267
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 266 0.264
response to other organism GO:0051707 293 0.241
positive regulation of biosynthetic process GO:0009891 316 0.232
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.225
negative regulation of cellular metabolic process GO:0031324 382 0.217
Human
protein modification process GO:0036211 438 0.216
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.216
macromolecular complex assembly GO:0065003 256 0.199
response to bacterium GO:0009617 198 0.189
purine ribonucleoside metabolic process GO:0046128 127 0.189
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 50 0.189
Yeast
nucleobase containing compound catabolic process GO:0034655 165 0.179
Yeast
single organism behavior GO:0044708 391 0.173
ribonucleotide metabolic process GO:0009259 145 0.173
Yeast
intracellular signal transduction GO:0035556 300 0.154
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.153
protein complex assembly GO:0006461 200 0.148
positive regulation of rna metabolic process GO:0051254 271 0.145
atp metabolic process GO:0046034 49 0.144
Yeast
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.140
Yeast
reproductive system development GO:0061458 74 0.137
regulation of cellular protein metabolic process GO:0032268 243 0.134
Human
nucleoside phosphate catabolic process GO:1901292 110 0.127
Yeast
purine ribonucleotide metabolic process GO:0009150 145 0.123
Yeast
microtubule organizing center organization GO:0031023 168 0.121
purine nucleotide catabolic process GO:0006195 109 0.118
Yeast
programmed cell death GO:0012501 257 0.116
Human
glycosyl compound catabolic process GO:1901658 112 0.116
Yeast
nucleotide metabolic process GO:0009117 161 0.112
Yeast
protein complex biogenesis GO:0070271 201 0.111
regulation of protein metabolic process GO:0051246 256 0.109
Human
organonitrogen compound metabolic process GO:1901564 318 0.108
Yeast
ribonucleoside catabolic process GO:0042454 112 0.107
Yeast
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.106
cellular protein modification process GO:0006464 438 0.106
Human
purine nucleoside metabolic process GO:0042278 127 0.104
Yeast
nucleoside metabolic process GO:0009116 127 0.103
Yeast
defense response to other organism GO:0098542 225 0.102
neurological system process GO:0050877 358 0.102
protein localization GO:0008104 284 0.100
Human Yeast
nucleoside phosphate metabolic process GO:0006753 162 0.100
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 119 0.099
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.098
Yeast
positive regulation of gene expression GO:0010628 290 0.096
cellular nitrogen compound catabolic process GO:0044270 165 0.094
Yeast
heterocycle catabolic process GO:0046700 166 0.094
Yeast
organic cyclic compound catabolic process GO:1901361 168 0.093
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 108 0.092
Yeast
death GO:0016265 284 0.091
Human
nucleoside triphosphate catabolic process GO:0009143 108 0.090
Yeast
phosphorylation GO:0016310 294 0.089
Human
nucleoside triphosphate metabolic process GO:0009141 120 0.089
Yeast
carbohydrate derivative catabolic process GO:1901136 118 0.085
Yeast
ribonucleoside metabolic process GO:0009119 127 0.083
Yeast
nucleoside monophosphate metabolic process GO:0009123 52 0.083
Yeast
nucleotide catabolic process GO:0009166 109 0.083
Yeast
organonitrogen compound biosynthetic process GO:1901566 117 0.082
negative regulation of gene expression GO:0010629 387 0.079
response to external biotic stimulus GO:0043207 293 0.078
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.078
Yeast
aromatic compound catabolic process GO:0019439 166 0.071
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.070
Yeast
positive regulation of response to stimulus GO:0048584 323 0.068
ribose phosphate metabolic process GO:0019693 145 0.067
Yeast
purine nucleotide metabolic process GO:0006163 146 0.064
Yeast
single organism catabolic process GO:0044712 228 0.064
Yeast
centrosome duplication GO:0051298 121 0.063
organonitrogen compound catabolic process GO:1901565 128 0.061
Yeast
cellular protein catabolic process GO:0044257 83 0.060
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 119 0.058
Yeast
ribonucleoside monophosphate metabolic process GO:0009161 51 0.058
Yeast
regulation of localization GO:0032879 275 0.056
Human
developmental growth GO:0048589 280 0.055
centrosome organization GO:0051297 163 0.054
defense response to bacterium GO:0042742 178 0.054
regulation of phosphorylation GO:0042325 147 0.052
Human
anatomical structure homeostasis GO:0060249 97 0.052
regulation of response to stress GO:0080134 200 0.052
Human
cellular macromolecule localization GO:0070727 220 0.051
Human Yeast
regulation of defense response GO:0031347 102 0.050
organophosphate metabolic process GO:0019637 195 0.049
Yeast
response to organic substance GO:0010033 284 0.049
Yeast
glycosyl compound metabolic process GO:1901657 127 0.049
Yeast
regulation of response to external stimulus GO:0032101 115 0.047
proteolysis GO:0006508 192 0.046
Yeast
response to biotic stimulus GO:0009607 294 0.045
defense response to gram negative bacterium GO:0050829 94 0.045
muscle cell differentiation GO:0042692 103 0.044
establishment of protein localization to organelle GO:0072594 62 0.044
Yeast
nucleosome organization GO:0034728 59 0.043
modification dependent macromolecule catabolic process GO:0043632 79 0.043
Yeast
protein catabolic process GO:0030163 101 0.042
Yeast
organelle fission GO:0048285 340 0.042
organophosphate catabolic process GO:0046434 112 0.042
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 39 0.042
Yeast
muscle structure development GO:0061061 224 0.041
negative regulation of developmental process GO:0051093 201 0.040
organic substance catabolic process GO:1901575 308 0.040
Yeast
regulation of protein modification process GO:0031399 112 0.040
Human
cellular homeostasis GO:0019725 80 0.039
positive regulation of transcription dna templated GO:0045893 266 0.039
male gamete generation GO:0048232 201 0.038
establishment of protein localization GO:0045184 163 0.038
Human Yeast
cellular response to chemical stimulus GO:0070887 199 0.038
regulation of transport GO:0051049 181 0.037
Human
camera type eye development GO:0043010 4 0.037
purine nucleoside monophosphate catabolic process GO:0009128 38 0.037
Yeast
regulation of protein localization GO:0032880 76 0.037
Human
posttranscriptional regulation of gene expression GO:0010608 145 0.036
purine nucleoside catabolic process GO:0006152 112 0.036
Yeast
cell death GO:0008219 279 0.036
Human
regulation of cell cycle GO:0051726 291 0.036
regulation of cell death GO:0010941 173 0.035
Human
regulation of mitotic cell cycle GO:0007346 190 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.035
Yeast
cell motility GO:0048870 251 0.035
response to endogenous stimulus GO:0009719 119 0.034
regulation of developmental growth GO:0048638 174 0.034
carbohydrate derivative metabolic process GO:1901135 217 0.034
Yeast
purine containing compound metabolic process GO:0072521 155 0.033
Yeast
reproductive structure development GO:0048608 74 0.033
rna catabolic process GO:0006401 37 0.032
imaginal disc derived wing morphogenesis GO:0007476 337 0.032
negative regulation of signaling GO:0023057 219 0.032
Human
modification dependent protein catabolic process GO:0019941 78 0.031
Yeast
cellular response to organic substance GO:0071310 132 0.031
centrosome cycle GO:0007098 137 0.031
production of molecular mediator of immune response GO:0002440 46 0.031
homeostatic process GO:0042592 199 0.030
body morphogenesis GO:0010171 2 0.030
single organism intracellular transport GO:1902582 207 0.028
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.028
Yeast
organic acid metabolic process GO:0006082 103 0.028
atp catabolic process GO:0006200 38 0.027
Yeast
endocytosis GO:0006897 310 0.027
negative regulation of protein metabolic process GO:0051248 85 0.027
Human
purine ribonucleotide catabolic process GO:0009154 109 0.027
Yeast
regulation of nucleocytoplasmic transport GO:0046822 35 0.027
positive regulation of protein import into nucleus GO:0042307 21 0.027
purine containing compound catabolic process GO:0072523 112 0.026
Yeast
regulation of translation GO:0006417 56 0.026
regulation of phosphate metabolic process GO:0019220 210 0.025
Human Yeast
regulation of molecular function GO:0065009 217 0.025
Human Yeast
regulation of cell division GO:0051302 72 0.025
rna interference GO:0016246 27 0.025
response to alcohol GO:0097305 95 0.025
spindle assembly GO:0051225 80 0.024
regulation of circadian rhythm GO:0042752 49 0.024
axis specification GO:0009798 167 0.024
adult behavior GO:0030534 137 0.024
mitotic cell cycle phase transition GO:0044772 138 0.024
protein phosphorylation GO:0006468 169 0.023
Human
positive regulation of cell communication GO:0010647 250 0.023
protein localization to organelle GO:0033365 82 0.023
Human Yeast
tube development GO:0035295 244 0.023
chromosome organization GO:0051276 360 0.023
positive regulation of multi organism process GO:0043902 40 0.022
ribonucleotide catabolic process GO:0009261 109 0.022
Yeast
organic substance transport GO:0071702 257 0.022
Human Yeast
protein maturation GO:0051604 71 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.022
Yeast
nucleoside monophosphate catabolic process GO:0009125 39 0.021
Yeast
determination of adult lifespan GO:0008340 137 0.021
Worm
aging GO:0007568 143 0.021
Worm
blastoderm segmentation GO:0007350 159 0.021
embryonic axis specification GO:0000578 107 0.021
positive regulation of signal transduction GO:0009967 223 0.021
protein targeting to nucleus GO:0044744 51 0.021
positive regulation of apoptotic signaling pathway GO:2001235 4 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
Human Yeast
regulation of cell proliferation GO:0042127 163 0.021
apoptotic signaling pathway GO:0097190 27 0.021
apoptotic process GO:0006915 159 0.021
Human
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
regulation of meiosis GO:0040020 3 0.020
mrna processing GO:0006397 104 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.020
Yeast
locomotory behavior GO:0007626 176 0.020
negative regulation of cell communication GO:0010648 223 0.020
Human
nuclear import GO:0051170 51 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
sex differentiation GO:0007548 81 0.019
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.019
positive regulation of immune response GO:0050778 63 0.019
lipid localization GO:0010876 54 0.019
regulation of protein import into nucleus GO:0042306 28 0.019
cell cycle phase transition GO:0044770 140 0.019
antimicrobial humoral response GO:0019730 99 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
Human
antimicrobial peptide production GO:0002775 46 0.018
nucleoside catabolic process GO:0009164 112 0.018
Yeast
defense response GO:0006952 300 0.018
regulation of catalytic activity GO:0050790 185 0.018
Human Yeast
response to temperature stimulus GO:0009266 106 0.017
epithelial cell differentiation GO:0030855 322 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
anterior posterior axis specification GO:0009948 109 0.017
protein import into nucleus GO:0006606 51 0.017
cell division GO:0051301 248 0.017
negative regulation of molecular function GO:0044092 51 0.017
Human
intracellular protein transport GO:0006886 104 0.017
Yeast
mapk cascade GO:0000165 107 0.017
Human
mitotic cell cycle checkpoint GO:0007093 88 0.017
response to extracellular stimulus GO:0009991 116 0.017
connective tissue development GO:0061448 3 0.017
circadian behavior GO:0048512 76 0.016
mitotic nuclear division GO:0007067 213 0.016
positive regulation of protein localization to nucleus GO:1900182 21 0.016
response to radiation GO:0009314 155 0.016
olfactory behavior GO:0042048 97 0.016
protein localization to nucleus GO:0034504 55 0.016
actin filament based process GO:0030029 220 0.016
regulation of immune system process GO:0002682 176 0.016
protein dna complex subunit organization GO:0071824 86 0.016
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.016
cytoplasmic microtubule organization GO:0031122 22 0.016
g1 s transition of mitotic cell cycle GO:0000082 31 0.016
regulation of synaptic transmission GO:0050804 69 0.016
sensory perception GO:0007600 196 0.016
positive regulation of signaling GO:0023056 243 0.015
development of primary sexual characteristics GO:0045137 50 0.015
protein k48 linked ubiquitination GO:0070936 3 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
vesicle mediated transport GO:0016192 381 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
Yeast
regulation of hemocyte proliferation GO:0035206 37 0.015
rna splicing GO:0008380 83 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
anterior posterior pattern specification GO:0009952 136 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
cellular protein complex assembly GO:0043623 71 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
Yeast
compound eye morphogenesis GO:0001745 249 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
regulation of neuron death GO:1901214 26 0.014
response to lipopolysaccharide GO:0032496 4 0.014
regulation of protein localization to nucleus GO:1900180 29 0.013
negative regulation of growth GO:0045926 84 0.013
growth GO:0040007 359 0.013
localization of cell GO:0051674 257 0.013
regulation of immune effector process GO:0002697 52 0.013
mrna 3 end processing GO:0031124 28 0.013
negative regulation of signal transduction GO:0009968 206 0.013
Human
macromolecule catabolic process GO:0009057 161 0.013
Yeast
positive regulation of transport GO:0051050 92 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
circulatory system development GO:0072359 82 0.013
small molecule metabolic process GO:0044281 305 0.013
Yeast
compound eye development GO:0048749 307 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
circadian rhythm GO:0007623 105 0.013
cellular response to endogenous stimulus GO:0071495 80 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
Human
regulation of cellular catabolic process GO:0031329 157 0.012
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.012
Yeast
regulation of programmed cell death GO:0043067 152 0.012
Human
tube morphogenesis GO:0035239 191 0.012
regulation of immune response GO:0050776 118 0.012
negative regulation of cell cycle GO:0045786 116 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
Yeast
cellular protein localization GO:0034613 160 0.012
Human Yeast
embryonic pattern specification GO:0009880 174 0.012
striated muscle cell differentiation GO:0051146 90 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
spindle assembly involved in mitosis GO:0090307 50 0.012
genitalia development GO:0048806 26 0.012
negative regulation of binding GO:0051100 5 0.012
regulation of production of molecular mediator of immune response GO:0002700 44 0.012
intracellular transport GO:0046907 228 0.012
Yeast
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
single organism cellular localization GO:1902580 180 0.012
Yeast
regulation of organelle organization GO:0033043 196 0.012
positive regulation of immune system process GO:0002684 68 0.011
nuclear division GO:0000280 332 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
response to nutrient levels GO:0031667 114 0.011
single organism nuclear import GO:1902593 51 0.011
gonad development GO:0008406 50 0.011
establishment of localization in cell GO:0051649 402 0.011
Yeast
kidney development GO:0001822 3 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
Yeast
larval development GO:0002164 104 0.011
regulation of apoptotic process GO:0042981 130 0.011
Human
amide biosynthetic process GO:0043604 42 0.011
chemotaxis GO:0006935 249 0.011
eye development GO:0001654 323 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
regulation of rna splicing GO:0043484 69 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
Human
immune effector process GO:0002252 98 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
alternative mrna splicing via spliceosome GO:0000380 60 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
Human
chemosensory behavior GO:0007635 106 0.011
protein import GO:0017038 55 0.011
Yeast
response to abiotic stimulus GO:0009628 341 0.010
protein processing GO:0016485 68 0.010
regulation of cell cycle process GO:0010564 181 0.010
maintenance of location GO:0051235 73 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
Yeast
signal release GO:0023061 49 0.010
positive regulation of translation GO:0045727 12 0.010
negative regulation of catalytic activity GO:0043086 42 0.010
Human
regulation of hydrolase activity GO:0051336 97 0.010
Yeast
response to organonitrogen compound GO:0010243 75 0.010

Droj2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.428
nervous system disease DOID:863 0 0.108
motor neuron disease DOID:231 0 0.070
central nervous system disease DOID:331 0 0.070
neurodegenerative disease DOID:1289 0 0.070
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.028