Drosophila melanogaster

41 known processes

pps (Dmel_CG6525)

protein partner of snf

(Aliases: CG6525,SPP,spp,Spp,Dmel\CG6525)

pps biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.091
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.075
chromatin modification GO:0016568 147 0.069
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.069
positive regulation of rna biosynthetic process GO:1902680 266 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.066
positive regulation of nucleic acid templated transcription GO:1903508 266 0.065
rna processing GO:0006396 147 0.064
positive regulation of cellular biosynthetic process GO:0031328 316 0.060
cellular catabolic process GO:0044248 372 0.059
positive regulation of biosynthetic process GO:0009891 316 0.059
regulation of protein metabolic process GO:0051246 256 0.057
regulation of response to stress GO:0080134 200 0.056
regionalization GO:0003002 416 0.054
carbohydrate derivative metabolic process GO:1901135 217 0.049
vesicle mediated transport GO:0016192 381 0.049
mrna metabolic process GO:0016071 124 0.047
wing disc morphogenesis GO:0007472 344 0.047
small molecule metabolic process GO:0044281 305 0.046
response to external biotic stimulus GO:0043207 293 0.046
purine ribonucleotide metabolic process GO:0009150 145 0.046
chromosome organization GO:0051276 360 0.045
phosphorylation GO:0016310 294 0.044
cellular macromolecular complex assembly GO:0034622 153 0.042
humoral immune response GO:0006959 117 0.042
organonitrogen compound metabolic process GO:1901564 318 0.042
establishment of localization in cell GO:0051649 402 0.041
catabolic process GO:0009056 409 0.040
positive regulation of transcription dna templated GO:0045893 266 0.040
macromolecular complex assembly GO:0065003 256 0.040
cellular protein modification process GO:0006464 438 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.038
organic acid metabolic process GO:0006082 103 0.037
cell death GO:0008219 279 0.036
positive regulation of rna metabolic process GO:0051254 271 0.036
imaginal disc derived appendage morphogenesis GO:0035114 395 0.035
compound eye morphogenesis GO:0001745 249 0.035
chromatin organization GO:0006325 207 0.035
response to other organism GO:0051707 293 0.034
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.033
organophosphate metabolic process GO:0019637 195 0.032
protein complex biogenesis GO:0070271 201 0.032
peptidyl amino acid modification GO:0018193 105 0.032
response to oxygen containing compound GO:1901700 200 0.032
response to biotic stimulus GO:0009607 294 0.031
ribonucleotide metabolic process GO:0009259 145 0.031
positive regulation of gene expression GO:0010628 290 0.031
compound eye development GO:0048749 307 0.030
nucleobase containing compound catabolic process GO:0034655 165 0.030
death GO:0016265 284 0.030
ribonucleoside monophosphate catabolic process GO:0009158 39 0.030
protein complex assembly GO:0006461 200 0.029
embryonic pattern specification GO:0009880 174 0.029
oxoacid metabolic process GO:0043436 103 0.029
lateral inhibition GO:0046331 206 0.029
developmental programmed cell death GO:0010623 138 0.029
covalent chromatin modification GO:0016569 106 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
mrna processing GO:0006397 104 0.028
organic substance catabolic process GO:1901575 308 0.028
single organism catabolic process GO:0044712 228 0.027
regulation of immune system process GO:0002682 176 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
negative regulation of nucleic acid templated transcription GO:1903507 240 0.027
protein modification process GO:0036211 438 0.027
response to abiotic stimulus GO:0009628 341 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
appendage morphogenesis GO:0035107 397 0.026
single organism intracellular transport GO:1902582 207 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
aromatic compound catabolic process GO:0019439 166 0.025
cellular amine metabolic process GO:0044106 12 0.025
histone modification GO:0016570 106 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
cell migration GO:0016477 238 0.024
regulation of cell differentiation GO:0045595 302 0.024
organic substance transport GO:0071702 257 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
intracellular signal transduction GO:0035556 300 0.024
rna splicing GO:0008380 83 0.024
regulation of localization GO:0032879 275 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
cytoplasmic transport GO:0016482 130 0.024
carboxylic acid metabolic process GO:0019752 92 0.023
ribonucleoside triphosphate catabolic process GO:0009203 108 0.023
anterior posterior pattern specification GO:0009952 136 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
forebrain development GO:0030900 2 0.023
nucleotide metabolic process GO:0009117 161 0.023
blastoderm segmentation GO:0007350 159 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
regulation of molecular function GO:0065009 217 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
atp metabolic process GO:0046034 49 0.022
central nervous system development GO:0007417 201 0.022
dna packaging GO:0006323 91 0.022
protein phosphorylation GO:0006468 169 0.022
rna localization GO:0006403 115 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
positive regulation of programmed cell death GO:0043068 62 0.021
nuclear transport GO:0051169 72 0.021
protein localization GO:0008104 284 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
sensory organ morphogenesis GO:0090596 260 0.021
eye photoreceptor cell development GO:0042462 81 0.021
brain development GO:0007420 120 0.021
defense response to bacterium GO:0042742 178 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
establishment of protein localization GO:0045184 163 0.021
multicellular organismal aging GO:0010259 140 0.020
response to bacterium GO:0009617 198 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.020
autophagy GO:0006914 108 0.020
localization of cell GO:0051674 257 0.020
connective tissue development GO:0061448 3 0.020
spindle organization GO:0007051 253 0.020
nucleocytoplasmic transport GO:0006913 72 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
exocrine system development GO:0035272 162 0.020
positive regulation of cell communication GO:0010647 250 0.020
salivary gland morphogenesis GO:0007435 145 0.019
segmentation GO:0035282 207 0.019
aging GO:0007568 143 0.019
protein alkylation GO:0008213 43 0.019
intracellular transport GO:0046907 228 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
endocytosis GO:0006897 310 0.019
eye development GO:0001654 323 0.019
programmed cell death GO:0012501 257 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
regulation of protein modification process GO:0031399 112 0.019
regulation of transport GO:0051049 181 0.019
appendage development GO:0048736 401 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.018
eye morphogenesis GO:0048592 260 0.018
regulation of cell cycle GO:0051726 291 0.018
positive regulation of signaling GO:0023056 243 0.018
regulation of response to external stimulus GO:0032101 115 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
gland development GO:0048732 191 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
regulation of cellular localization GO:0060341 136 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
body morphogenesis GO:0010171 2 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
regulation of cellular response to stress GO:0080135 89 0.018
cellular macromolecule localization GO:0070727 220 0.018
antimicrobial humoral response GO:0019730 99 0.018
regulation of multi organism process GO:0043900 131 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
defense response to other organism GO:0098542 225 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.017
multi organism behavior GO:0051705 175 0.017
salivary gland development GO:0007431 162 0.017
regulation of programmed cell death GO:0043067 152 0.017
mitotic spindle organization GO:0007052 220 0.017
chromatin remodeling GO:0006338 72 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
regulation of organelle organization GO:0033043 196 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
photoreceptor cell development GO:0042461 96 0.017
negative regulation of gene expression GO:0010629 387 0.017
cellular amino acid metabolic process GO:0006520 61 0.016
regulation of immune effector process GO:0002697 52 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
amine metabolic process GO:0009308 12 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
autophagic cell death GO:0048102 83 0.016
histone methylation GO:0016571 40 0.016
camera type eye development GO:0043010 4 0.016
proteolysis GO:0006508 192 0.016
single organism biosynthetic process GO:0044711 206 0.016
positive regulation of signal transduction GO:0009967 223 0.016
purine nucleoside monophosphate metabolic process GO:0009126 50 0.016
neurological system process GO:0050877 358 0.016
single organism cellular localization GO:1902580 180 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
rna 3 end processing GO:0031123 45 0.016
histone h3 k4 methylation GO:0051568 16 0.016
compound eye photoreceptor development GO:0042051 78 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
heterocycle catabolic process GO:0046700 166 0.015
gland morphogenesis GO:0022612 145 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
determination of adult lifespan GO:0008340 137 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
male gamete generation GO:0048232 201 0.015
cell motility GO:0048870 251 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
organophosphate catabolic process GO:0046434 112 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
purine containing compound metabolic process GO:0072521 155 0.015
dna metabolic process GO:0006259 227 0.015
phagocytosis GO:0006909 215 0.015
organelle fission GO:0048285 340 0.015
actin filament based process GO:0030029 220 0.015
positive regulation of transport GO:0051050 92 0.015
multi multicellular organism process GO:0044706 123 0.015
regulation of cellular amide metabolic process GO:0034248 39 0.015
glycosyl compound catabolic process GO:1901658 112 0.014
regulation of phosphorylation GO:0042325 147 0.014
positive regulation of proteolysis GO:0045862 52 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
ameboidal type cell migration GO:0001667 151 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
multi organism reproductive behavior GO:0044705 121 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
regulation of catalytic activity GO:0050790 185 0.014
regulation of cell shape GO:0008360 113 0.014
ras protein signal transduction GO:0007265 88 0.014
regulation of cell death GO:0010941 173 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
jak stat cascade GO:0007259 49 0.014
regulation of cell cycle process GO:0010564 181 0.014
nucleoside metabolic process GO:0009116 127 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
mitotic nuclear division GO:0007067 213 0.014
protein transport GO:0015031 155 0.013
negative regulation of developmental process GO:0051093 201 0.013
pole plasm assembly GO:0007315 61 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
axis specification GO:0009798 167 0.013
response to lipopolysaccharide GO:0032496 4 0.013
reproductive behavior GO:0019098 122 0.013
negative regulation of signaling GO:0023057 219 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
immune effector process GO:0002252 98 0.013
peptide biosynthetic process GO:0043043 42 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
regulation of apoptotic process GO:0042981 130 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
positive regulation of cell death GO:0010942 69 0.013
spermatogenesis GO:0007283 200 0.013
nuclear division GO:0000280 332 0.013
signal transduction in response to dna damage GO:0042770 3 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
protein maturation GO:0051604 71 0.012
peptidyl lysine modification GO:0018205 57 0.012
cellular protein complex assembly GO:0043623 71 0.012
nucleosome organization GO:0034728 59 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
response to ecdysone GO:0035075 34 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
macromolecule methylation GO:0043414 45 0.012
cellular protein localization GO:0034613 160 0.012
apoptotic process GO:0006915 159 0.012
salivary gland histolysis GO:0035070 88 0.012
regulation of proteolysis GO:0030162 87 0.012
histolysis GO:0007559 102 0.012
regulation of chromatin modification GO:1903308 28 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
regulation of anatomical structure size GO:0090066 163 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
response to sterol GO:0036314 34 0.012
response to organic substance GO:0010033 284 0.012
antimicrobial peptide production GO:0002775 46 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
response to organophosphorus GO:0046683 2 0.012
tissue morphogenesis GO:0048729 297 0.012
phenol containing compound metabolic process GO:0018958 57 0.012
positive regulation of peptidase activity GO:0010952 29 0.012
negative regulation of cell communication GO:0010648 223 0.012
head development GO:0060322 135 0.012
peptidyl lysine acetylation GO:0018394 39 0.012
regulation of protein complex assembly GO:0043254 42 0.012
epithelial cell differentiation GO:0030855 322 0.011
dendrite development GO:0016358 204 0.011
nucleoside catabolic process GO:0009164 112 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
response to temperature stimulus GO:0009266 106 0.011
response to heat GO:0009408 63 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.011
regulation of chromatin organization GO:1902275 32 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
organelle localization GO:0051640 148 0.011
regulation of cellular component size GO:0032535 98 0.011
single organism behavior GO:0044708 391 0.011
cell cycle phase transition GO:0044770 140 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
response to oxygen levels GO:0070482 59 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
dendrite morphogenesis GO:0048813 199 0.011
growth GO:0040007 359 0.011
endomembrane system organization GO:0010256 119 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
negative regulation of cell death GO:0060548 81 0.011
immune system process GO:0002376 347 0.011
actin cytoskeleton organization GO:0030036 206 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
regulation of chromosome organization GO:0033044 64 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
tissue migration GO:0090130 155 0.011
regulation of developmental growth GO:0048638 174 0.010
negative regulation of cell cycle phase transition GO:1901988 103 0.010
stem cell maintenance GO:0019827 67 0.010
innate immune response GO:0045087 144 0.010
regulation of antimicrobial peptide production GO:0002784 44 0.010
negative regulation of signal transduction GO:0009968 206 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
positive regulation of apoptotic process GO:0043065 47 0.010
regulation of humoral immune response GO:0002920 51 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
synaptic transmission GO:0007268 288 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
developmental maturation GO:0021700 172 0.010
regulation of hydrolase activity GO:0051336 97 0.010
response to alcohol GO:0097305 95 0.010

pps disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.012