Drosophila melanogaster

94 known processes

bic (Dmel_CG3644)

bicaudal

(Aliases: Dmel\CG3644,l(2)k10712,E(2)Bic,l(2)49Da,BcDNA:GM05329,Bic,BcDNA.GM05329,Btf,vr22,E(Bic),CG3644,5A,107/12,l(2)vr22)

bic biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic development via the syncytial blastoderm GO:0001700 148 0.475
tripartite regional subdivision GO:0007351 103 0.420
blastoderm segmentation GO:0007350 159 0.401
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.363
regulation of reproductive process GO:2000241 54 0.349
anterior posterior pattern specification GO:0009952 136 0.337
pole plasm oskar mrna localization GO:0045451 46 0.251
oocyte axis specification GO:0007309 108 0.228
maternal determination of anterior posterior axis embryo GO:0008358 74 0.224
anterior posterior axis specification embryo GO:0008595 103 0.212
segmentation GO:0035282 207 0.211
regulation of multi organism process GO:0043900 131 0.208
embryonic axis specification GO:0000578 107 0.191
endocytosis GO:0006897 310 0.173
Worm
anterior posterior axis specification GO:0009948 109 0.164
dorsal ventral pattern formation GO:0009953 133 0.160
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.145
small molecule metabolic process GO:0044281 305 0.142
axis specification GO:0009798 167 0.138
cell motility GO:0048870 251 0.135
Worm
pole plasm mrna localization GO:0019094 49 0.132
transcription from rna polymerase ii promoter GO:0006366 368 0.129
organonitrogen compound metabolic process GO:1901564 318 0.123
oocyte development GO:0048599 124 0.121
embryonic pattern specification GO:0009880 174 0.118
embryo development ending in birth or egg hatching GO:0009792 152 0.117
positive regulation of developmental process GO:0051094 143 0.115
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.114
mitotic spindle organization GO:0007052 220 0.108
positive regulation of transcription dna templated GO:0045893 266 0.105
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.103
mitochondrion organization GO:0007005 65 0.103
oocyte construction GO:0007308 112 0.098
regulation of cell development GO:0060284 215 0.098
negative regulation of signaling GO:0023057 219 0.095
vesicle mediated transport GO:0016192 381 0.094
Worm
regulation of pole plasm oskar mrna localization GO:0007317 27 0.089
regulation of molecular function GO:0065009 217 0.089
regulation of cellular component biogenesis GO:0044087 201 0.087
pole plasm rna localization GO:0007316 52 0.085
cellular catabolic process GO:0044248 372 0.084
positive regulation of cellular biosynthetic process GO:0031328 316 0.083
regulation of behavior GO:0050795 75 0.082
spindle organization GO:0007051 253 0.082
positive regulation of rna biosynthetic process GO:1902680 266 0.081
cell proliferation GO:0008283 299 0.080
body morphogenesis GO:0010171 2 0.080
Worm
regulation of developmental growth GO:0048638 174 0.074
programmed cell death GO:0012501 257 0.073
Worm
associative learning GO:0008306 65 0.072
regulation of epithelial cell differentiation GO:0030856 4 0.066
positive regulation of nucleic acid templated transcription GO:1903508 266 0.065
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.063
positive regulation of macromolecule metabolic process GO:0010604 405 0.063
axon guidance GO:0007411 233 0.062
developmental growth GO:0048589 280 0.060
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.060
regulation of cellular localization GO:0060341 136 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.059
oocyte anterior posterior axis specification GO:0007314 72 0.059
organic substance catabolic process GO:1901575 308 0.058
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.056
regulation of programmed cell death GO:0043067 152 0.056
Worm
ameboidal type cell migration GO:0001667 151 0.056
regulation of oocyte development GO:0060281 27 0.056
regulation of multicellular organism growth GO:0040014 40 0.055
response to light stimulus GO:0009416 124 0.054
protein complex biogenesis GO:0070271 201 0.052
positive regulation of biosynthetic process GO:0009891 316 0.052
response to other organism GO:0051707 293 0.052
oocyte differentiation GO:0009994 145 0.052
catabolic process GO:0009056 409 0.051
immune system process GO:0002376 347 0.050
single organism catabolic process GO:0044712 228 0.048
response to temperature stimulus GO:0009266 106 0.048
cell death GO:0008219 279 0.047
Worm
enzyme linked receptor protein signaling pathway GO:0007167 179 0.047
cell division GO:0051301 248 0.047
regionalization GO:0003002 416 0.047
chromosome organization GO:0051276 360 0.047
phosphorylation GO:0016310 294 0.046
axonogenesis GO:0007409 290 0.046
regulation of cell death GO:0010941 173 0.046
Worm
cell maturation GO:0048469 144 0.046
eye development GO:0001654 323 0.044
macromolecular complex assembly GO:0065003 256 0.043
positive regulation of gene expression GO:0010628 290 0.041
cellular response to organic substance GO:0071310 132 0.041
cellular protein catabolic process GO:0044257 83 0.041
heterocycle catabolic process GO:0046700 166 0.040
regulation of catabolic process GO:0009894 170 0.040
purine nucleoside triphosphate metabolic process GO:0009144 119 0.039
central nervous system development GO:0007417 201 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.038
chromatin modification GO:0016568 147 0.038
positive regulation of rna metabolic process GO:0051254 271 0.037
epithelial cell differentiation GO:0030855 322 0.037
negative regulation of gene expression GO:0010629 387 0.037
positive regulation of molecular function GO:0044093 136 0.037
regulation of cellular catabolic process GO:0031329 157 0.036
nuclear division GO:0000280 332 0.036
cellular amine metabolic process GO:0044106 12 0.036
immune effector process GO:0002252 98 0.035
nucleoside triphosphate catabolic process GO:0009143 108 0.035
wing disc morphogenesis GO:0007472 344 0.035
rna localization GO:0006403 115 0.034
ribonucleoside metabolic process GO:0009119 127 0.034
intracellular mrna localization GO:0008298 66 0.034
synaptic transmission GO:0007268 288 0.034
nucleoside phosphate metabolic process GO:0006753 162 0.033
positive regulation of developmental growth GO:0048639 62 0.033
establishment of localization in cell GO:0051649 402 0.033
Yeast
tissue migration GO:0090130 155 0.033
neurological system process GO:0050877 358 0.033
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
multicellular organismal reproductive behavior GO:0033057 110 0.032
cellular amino acid metabolic process GO:0006520 61 0.031
appendage development GO:0048736 401 0.031
ribonucleotide catabolic process GO:0009261 109 0.031
cellular nitrogen compound catabolic process GO:0044270 165 0.031
cellular macromolecular complex assembly GO:0034622 153 0.031
developmental maturation GO:0021700 172 0.031
single organism cellular localization GO:1902580 180 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.031
embryonic morphogenesis GO:0048598 206 0.030
axon development GO:0061564 297 0.030
glycosyl compound metabolic process GO:1901657 127 0.030
regulation of protein metabolic process GO:0051246 256 0.030
establishment or maintenance of cell polarity GO:0007163 167 0.030
nucleotide catabolic process GO:0009166 109 0.030
rna processing GO:0006396 147 0.029
purine ribonucleotide metabolic process GO:0009150 145 0.029
regulation of cell maturation GO:1903429 27 0.029
regulation of apoptotic process GO:0042981 130 0.029
Worm
neuromuscular junction development GO:0007528 149 0.029
epidermis development GO:0008544 65 0.029
cellular macromolecule catabolic process GO:0044265 136 0.029
gonad development GO:0008406 50 0.028
Worm
oxoacid metabolic process GO:0043436 103 0.028
post embryonic appendage morphogenesis GO:0035120 385 0.028
compound eye development GO:0048749 307 0.028
melanin metabolic process GO:0006582 47 0.027
negative regulation of cellular biosynthetic process GO:0031327 277 0.027
purine nucleotide catabolic process GO:0006195 109 0.027
macromolecule catabolic process GO:0009057 161 0.027
regulation of mitotic cell cycle GO:0007346 190 0.027
imaginal disc pattern formation GO:0007447 91 0.027
response to carbon dioxide GO:0010037 4 0.026
organic acid metabolic process GO:0006082 103 0.026
regulation of catalytic activity GO:0050790 185 0.026
establishment of organelle localization GO:0051656 122 0.026
regulation of epithelial cell proliferation GO:0050678 4 0.026
protein catabolic process GO:0030163 101 0.025
purine containing compound metabolic process GO:0072521 155 0.025
nucleoside metabolic process GO:0009116 127 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
positive regulation of multicellular organism growth GO:0040018 21 0.025
guanosine containing compound catabolic process GO:1901069 74 0.024
appendage morphogenesis GO:0035107 397 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
kidney epithelium development GO:0072073 3 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
organophosphate catabolic process GO:0046434 112 0.023
mesenchymal cell differentiation GO:0048762 1 0.023
protein transport GO:0015031 155 0.023
Yeast
nucleoside catabolic process GO:0009164 112 0.022
detection of stimulus GO:0051606 156 0.022
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.022
photoreceptor cell development GO:0042461 96 0.022
chromatin organization GO:0006325 207 0.022
positive regulation of antimicrobial humoral response GO:0002760 28 0.022
chemical homeostasis GO:0048878 92 0.022
immune response GO:0006955 246 0.021
negative regulation of cell cycle process GO:0010948 109 0.021
apoptotic process GO:0006915 159 0.021
Worm
regulation of response to external stimulus GO:0032101 115 0.021
response to organic substance GO:0010033 284 0.021
protein modification process GO:0036211 438 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
purine containing compound catabolic process GO:0072523 112 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
regulation of phosphate metabolic process GO:0019220 210 0.020
nuclear transport GO:0051169 72 0.020
epithelial cell development GO:0002064 274 0.020
proteolysis GO:0006508 192 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
synapse organization GO:0050808 196 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
multicellular organism growth GO:0035264 46 0.020
learning GO:0007612 75 0.019
secondary metabolic process GO:0019748 75 0.019
actin filament based process GO:0030029 220 0.019
pronuclear migration GO:0035046 4 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
pole plasm assembly GO:0007315 61 0.019
response to abiotic stimulus GO:0009628 341 0.019
sensory perception GO:0007600 196 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
cell cycle phase transition GO:0044770 140 0.019
mitotic nuclear division GO:0007067 213 0.019
regulation of embryonic development GO:0045995 68 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
regulation of cell differentiation GO:0045595 302 0.018
camera type eye development GO:0043010 4 0.018
rhodopsin mediated signaling pathway GO:0016056 21 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
determination of adult lifespan GO:0008340 137 0.018
positive regulation of growth GO:0045927 75 0.018
negative regulation of rna metabolic process GO:0051253 251 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
regulation of hydrolase activity GO:0051336 97 0.017
organelle localization GO:0051640 148 0.017
reproductive behavior GO:0019098 122 0.017
neuron projection guidance GO:0097485 241 0.017
rna splicing via transesterification reactions GO:0000375 73 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
cell migration GO:0016477 238 0.017
Worm
chemosensory behavior GO:0007635 106 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
organelle fission GO:0048285 340 0.017
epithelial cell migration GO:0010631 148 0.017
olfactory learning GO:0008355 56 0.016
regulation of locomotion GO:0040012 42 0.016
regulation of rna splicing GO:0043484 69 0.016
defense response GO:0006952 300 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
response to radiation GO:0009314 155 0.016
regulation of transport GO:0051049 181 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
cognition GO:0050890 141 0.016
homeostatic process GO:0042592 199 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.015
single organism intracellular transport GO:1902582 207 0.015
Yeast
negative regulation of cell communication GO:0010648 223 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
localization of cell GO:0051674 257 0.015
Worm
purine ribonucleotide catabolic process GO:0009154 109 0.015
chromatin remodeling GO:0006338 72 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
aromatic compound catabolic process GO:0019439 166 0.015
organophosphate metabolic process GO:0019637 195 0.015
limb morphogenesis GO:0035108 1 0.015
protein maturation GO:0051604 71 0.015
cortical cytoskeleton organization GO:0030865 29 0.015
biological adhesion GO:0022610 138 0.014
signal release GO:0023061 49 0.014
single organism behavior GO:0044708 391 0.014
intracellular transport GO:0046907 228 0.014
Yeast
protein localization GO:0008104 284 0.014
mitotic spindle elongation GO:0000022 81 0.014
retina development in camera type eye GO:0060041 4 0.014
phototransduction visible light GO:0007603 27 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.014
nucleotide metabolic process GO:0009117 161 0.014
compound eye morphogenesis GO:0001745 249 0.014
regulation of embryonic pattern specification GO:1902875 27 0.014
regulation of production of molecular mediator of immune response GO:0002700 44 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
memory GO:0007613 94 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
developmental programmed cell death GO:0010623 138 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
multicellular organismal aging GO:0010259 140 0.013
organelle assembly GO:0070925 198 0.013
humoral immune response GO:0006959 117 0.013
response to biotic stimulus GO:0009607 294 0.013
regulation of mrna processing GO:0050684 71 0.013
regulation of humoral immune response GO:0002920 51 0.013
regulation of cell proliferation GO:0042127 163 0.013
dorsal ventral axis specification GO:0009950 66 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
mrna metabolic process GO:0016071 124 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
sensory organ morphogenesis GO:0090596 260 0.012
smoothened signaling pathway GO:0007224 49 0.012
camera type eye morphogenesis GO:0048593 2 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
peptidyl amino acid modification GO:0018193 105 0.012
cellular macromolecule localization GO:0070727 220 0.012
anatomical structure homeostasis GO:0060249 97 0.012
regulation of cellular component size GO:0032535 98 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
phagocytosis GO:0006909 215 0.012
gtp catabolic process GO:0006184 72 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
multi multicellular organism process GO:0044706 123 0.012
phenol containing compound metabolic process GO:0018958 57 0.012
actin filament organization GO:0007015 126 0.012
limb development GO:0060173 1 0.012
regulation of meiosis GO:0040020 3 0.012
protein complex assembly GO:0006461 200 0.011
regulation of smoothened signaling pathway GO:0008589 28 0.011
amide biosynthetic process GO:0043604 42 0.011
death GO:0016265 284 0.011
Worm
carboxylic acid metabolic process GO:0019752 92 0.011
lipid metabolic process GO:0006629 121 0.011
translation GO:0006412 69 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
protein processing GO:0016485 68 0.011
molting cycle chitin based cuticle GO:0007591 56 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
response to external biotic stimulus GO:0043207 293 0.011
sleep GO:0030431 49 0.011
regulation of immune effector process GO:0002697 52 0.011
negative regulation of organelle organization GO:0010639 56 0.011
asymmetric protein localization GO:0008105 33 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
learning or memory GO:0007611 141 0.011
cytoplasm organization GO:0007028 64 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
Yeast
autophagy GO:0006914 108 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.010
regulation of cell cycle GO:0051726 291 0.010
taxis GO:0042330 304 0.010
regulation of nuclear division GO:0051783 58 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
regulation of neurotransmitter levels GO:0001505 38 0.010

bic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.021
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010