Drosophila melanogaster

45 known processes

moi (Dmel_CG42350)

modigliani

(Aliases: tlu,Dmel\CG42350,CG42350,0967/13,l(3)S096713,l(3)CB02140,Dromel_CG31241_FBtr0083570_dtl_uORF,Dtl uORF,DTLu)

moi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.500
telomere capping GO:0016233 11 0.499
immune system process GO:0002376 347 0.238
locomotory behavior GO:0007626 176 0.234
homeostatic process GO:0042592 199 0.168
regulation of multicellular organismal development GO:2000026 414 0.168
chromosome organization GO:0051276 360 0.165
immune response GO:0006955 246 0.136
cell cell signaling involved in cell fate commitment GO:0045168 210 0.136
regulation of nervous system development GO:0051960 248 0.120
regulation of cell death GO:0010941 173 0.118
regulation of anatomical structure morphogenesis GO:0022603 242 0.118
localization of cell GO:0051674 257 0.118
cell adhesion GO:0007155 136 0.097
adult locomotory behavior GO:0008344 76 0.089
gene silencing GO:0016458 138 0.085
positive regulation of response to stimulus GO:0048584 323 0.084
posttranscriptional gene silencing GO:0016441 46 0.082
regulation of neurogenesis GO:0050767 158 0.081
axon cargo transport GO:0008088 29 0.080
regulation of gene expression epigenetic GO:0040029 128 0.079
cell death GO:0008219 279 0.078
negative regulation of gene expression GO:0010629 387 0.077
positive regulation of immune response GO:0050778 63 0.075
biological adhesion GO:0022610 138 0.073
death GO:0016265 284 0.073
cation transmembrane transport GO:0098655 88 0.073
intracellular signal transduction GO:0035556 300 0.073
neurological system process GO:0050877 358 0.072
lateral inhibition GO:0046331 206 0.071
sensory perception GO:0007600 196 0.069
gene silencing by rna GO:0031047 57 0.069
dna metabolic process GO:0006259 227 0.068
secretion GO:0046903 109 0.068
posttranscriptional gene silencing by rna GO:0035194 45 0.067
eye morphogenesis GO:0048592 260 0.067
metal ion transport GO:0030001 74 0.067
posttranscriptional regulation of gene expression GO:0010608 145 0.063
eye photoreceptor cell differentiation GO:0001754 145 0.061
central nervous system development GO:0007417 201 0.059
transition metal ion homeostasis GO:0055076 17 0.056
positive regulation of cell communication GO:0010647 250 0.056
regulation of cell differentiation GO:0045595 302 0.055
regulation of immune response GO:0050776 118 0.055
border follicle cell migration GO:0007298 113 0.055
inorganic cation transmembrane transport GO:0098662 61 0.054
cytoskeleton dependent intracellular transport GO:0030705 44 0.054
programmed cell death GO:0012501 257 0.054
zinc ion homeostasis GO:0055069 6 0.053
gland development GO:0048732 191 0.052
anatomical structure homeostasis GO:0060249 97 0.051
apoptotic process GO:0006915 159 0.051
muscle structure development GO:0061061 224 0.051
regulation of programmed cell death GO:0043067 152 0.049
oxoacid metabolic process GO:0043436 103 0.049
ion transport GO:0006811 145 0.048
adult behavior GO:0030534 137 0.048
protein modification process GO:0036211 438 0.048
regulation of immune system process GO:0002682 176 0.048
positive regulation of rna metabolic process GO:0051254 271 0.047
establishment of localization in cell GO:0051649 402 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.045
chemical homeostasis GO:0048878 92 0.044
regulation of dendrite development GO:0050773 37 0.044
regulation of cellular ketone metabolic process GO:0010565 3 0.044
epithelial cell differentiation GO:0030855 322 0.043
gene silencing by mirna GO:0035195 22 0.043
cell motility GO:0048870 251 0.042
cellular macromolecular complex assembly GO:0034622 153 0.042
regulation of neuron differentiation GO:0045664 103 0.042
positive regulation of signaling GO:0023056 243 0.042
cellular protein modification process GO:0006464 438 0.041
dorsal ventral pattern formation GO:0009953 133 0.041
notch signaling pathway GO:0007219 120 0.040
metal ion homeostasis GO:0055065 44 0.040
response to organic substance GO:0010033 284 0.038
eye development GO:0001654 323 0.038
sensory organ morphogenesis GO:0090596 260 0.038
mapk cascade GO:0000165 107 0.038
developmental growth GO:0048589 280 0.037
cellular amino acid metabolic process GO:0006520 61 0.037
small molecule metabolic process GO:0044281 305 0.036
positive regulation of immune system process GO:0002684 68 0.036
negative regulation of programmed cell death GO:0043069 72 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.034
regulation of phosphorylation GO:0042325 147 0.034
negative regulation of apoptotic process GO:0043066 63 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.034
axon development GO:0061564 297 0.033
carbohydrate derivative biosynthetic process GO:1901137 85 0.033
response to oxygen containing compound GO:1901700 200 0.033
response to oxidative stress GO:0006979 86 0.033
regulation of cell shape GO:0008360 113 0.032
positive regulation of defense response GO:0031349 59 0.032
endomembrane system organization GO:0010256 119 0.032
negative regulation of cell differentiation GO:0045596 143 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
response to biotic stimulus GO:0009607 294 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.031
regulation of apoptotic process GO:0042981 130 0.031
mesoderm development GO:0007498 78 0.031
phosphorylation GO:0016310 294 0.030
compound eye development GO:0048749 307 0.030
regulation of cellular amine metabolic process GO:0033238 3 0.030
positive regulation of developmental process GO:0051094 143 0.030
negative regulation of neurogenesis GO:0050768 53 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
sensory perception of chemical stimulus GO:0007606 116 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
cardiovascular system development GO:0072358 82 0.029
regulation of intracellular signal transduction GO:1902531 236 0.028
regionalization GO:0003002 416 0.028
axis specification GO:0009798 167 0.028
regulation of cell projection organization GO:0031344 92 0.027
appendage development GO:0048736 401 0.027
cellular ketone metabolic process GO:0042180 24 0.027
cell migration GO:0016477 238 0.027
embryonic development via the syncytial blastoderm GO:0001700 148 0.026
establishment of protein localization GO:0045184 163 0.026
immune response activating signal transduction GO:0002757 2 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
immune response regulating signaling pathway GO:0002764 2 0.025
positive regulation of histone deacetylation GO:0031065 2 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.025
positive regulation of protein metabolic process GO:0051247 128 0.024
regulation of protein metabolic process GO:0051246 256 0.024
signal transduction by phosphorylation GO:0023014 107 0.024
detection of chemical stimulus GO:0009593 93 0.024
single organism carbohydrate metabolic process GO:0044723 72 0.024
head involution GO:0008258 35 0.024
dna conformation change GO:0071103 105 0.024
response to external biotic stimulus GO:0043207 293 0.024
response to alcohol GO:0097305 95 0.024
negative regulation of biosynthetic process GO:0009890 277 0.023
inorganic ion transmembrane transport GO:0098660 73 0.023
glycoprotein biosynthetic process GO:0009101 41 0.023
r7 cell differentiation GO:0045466 43 0.023
positive regulation of cell development GO:0010720 61 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
macromolecular complex assembly GO:0065003 256 0.022
chemotaxis GO:0006935 249 0.022
detection of stimulus GO:0051606 156 0.022
tissue morphogenesis GO:0048729 297 0.022
telomere organization GO:0032200 21 0.022
positive regulation of phosphorylation GO:0042327 87 0.022
single organism biosynthetic process GO:0044711 206 0.022
positive regulation of signal transduction GO:0009967 223 0.022
camera type eye development GO:0043010 4 0.022
regulation of developmental growth GO:0048638 174 0.022
microtubule based movement GO:0007018 51 0.021
transition metal ion transport GO:0000041 16 0.021
cellular response to organic substance GO:0071310 132 0.021
defense response GO:0006952 300 0.021
single organism cellular localization GO:1902580 180 0.021
cellular amine metabolic process GO:0044106 12 0.020
catecholamine biosynthetic process GO:0042423 3 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
positive regulation of molecular function GO:0044093 136 0.020
regulation of growth GO:0040008 233 0.020
compound eye morphogenesis GO:0001745 249 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
regulation of cell morphogenesis GO:0022604 163 0.020
germ band shortening GO:0007390 19 0.020
regulation of transport GO:0051049 181 0.020
chaeta development GO:0022416 97 0.019
hindbrain development GO:0030902 2 0.019
vesicle mediated transport GO:0016192 381 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
golgi organization GO:0007030 66 0.019
amine metabolic process GO:0009308 12 0.019
cation transport GO:0006812 110 0.019
cellular catabolic process GO:0044248 372 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
negative regulation of cell development GO:0010721 62 0.019
lymph gland development GO:0048542 28 0.019
chromatin assembly or disassembly GO:0006333 52 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
organic hydroxy compound biosynthetic process GO:1901617 21 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
microtubule based transport GO:0010970 42 0.018
connective tissue development GO:0061448 3 0.018
organic hydroxy compound metabolic process GO:1901615 83 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
immune system development GO:0002520 57 0.018
salivary gland morphogenesis GO:0007435 145 0.018
response to radiation GO:0009314 155 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
developmental growth involved in morphogenesis GO:0060560 65 0.018
circulatory system development GO:0072359 82 0.018
sensory organ precursor cell fate determination GO:0016360 19 0.018
embryonic morphogenesis GO:0048598 206 0.018
rna processing GO:0006396 147 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
cell fate specification GO:0001708 71 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
organelle fission GO:0048285 340 0.017
synaptic transmission GO:0007268 288 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
regulation of molecular function GO:0065009 217 0.017
regulation of defense response GO:0031347 102 0.017
divalent inorganic cation homeostasis GO:0072507 29 0.017
negative regulation of cell communication GO:0010648 223 0.017
forebrain development GO:0030900 2 0.017
regulation of mapk cascade GO:0043408 92 0.017
mitochondrion organization GO:0007005 65 0.017
negative regulation of neuron death GO:1901215 18 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
regulation of response to stress GO:0080134 200 0.016
gland morphogenesis GO:0022612 145 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
ovarian follicle cell migration GO:0007297 121 0.016
response to extracellular stimulus GO:0009991 116 0.016
regulation of transferase activity GO:0051338 58 0.016
salivary gland cell autophagic cell death GO:0035071 83 0.016
response to bacterium GO:0009617 198 0.016
organic substance transport GO:0071702 257 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
protein phosphorylation GO:0006468 169 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
regulation of wound healing GO:0061041 13 0.015
protein localization GO:0008104 284 0.015
regulation of innate immune response GO:0045088 71 0.015
negative regulation of signal transduction GO:0009968 206 0.015
telomere maintenance GO:0000723 21 0.015
cholesterol homeostasis GO:0042632 3 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
positive regulation of cell death GO:0010942 69 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
regulation of localization GO:0032879 275 0.015
peptidyl amino acid modification GO:0018193 105 0.015
cellular amide metabolic process GO:0043603 80 0.015
imaginal disc fusion GO:0046528 19 0.014
aging GO:0007568 143 0.014
carbohydrate metabolic process GO:0005975 82 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
molting cycle chitin based cuticle GO:0007591 56 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
positive regulation of protein phosphorylation GO:0001934 34 0.014
regulation of protein stability GO:0031647 43 0.014
cell fate determination GO:0001709 91 0.014
regulation of catalytic activity GO:0050790 185 0.014
segmentation GO:0035282 207 0.014
salivary gland histolysis GO:0035070 88 0.014
smoothened signaling pathway GO:0007224 49 0.014
glycoprotein metabolic process GO:0009100 41 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
regulation of catabolic process GO:0009894 170 0.014
embryonic axis specification GO:0000578 107 0.014
somatic muscle development GO:0007525 66 0.014
immune effector process GO:0002252 98 0.014
endoderm formation GO:0001706 3 0.014
extracellular matrix organization GO:0030198 32 0.014
organic substance catabolic process GO:1901575 308 0.013
negative regulation of nervous system development GO:0051961 92 0.013
response to other organism GO:0051707 293 0.013
catabolic process GO:0009056 409 0.013
single organism intracellular transport GO:1902582 207 0.013
copper ion homeostasis GO:0055070 7 0.013
cardiocyte differentiation GO:0035051 29 0.013
negative regulation of notch signaling pathway GO:0045746 41 0.013
developmental programmed cell death GO:0010623 138 0.013
signal transduction in response to dna damage GO:0042770 3 0.013
regulation of kinase activity GO:0043549 53 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
cell type specific apoptotic process GO:0097285 38 0.013
regulation of cell development GO:0060284 215 0.013
aromatic compound catabolic process GO:0019439 166 0.013
autophagic cell death GO:0048102 83 0.013
negative regulation of cell death GO:0060548 81 0.012
protein transport GO:0015031 155 0.012
single organism behavior GO:0044708 391 0.012
aromatic amino acid family metabolic process GO:0009072 3 0.012
sensory perception of sound GO:0007605 56 0.012
endoplasmic reticulum organization GO:0007029 13 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
vitamin metabolic process GO:0006766 2 0.012
axon guidance GO:0007411 233 0.012
cellular macromolecule localization GO:0070727 220 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
genital disc development GO:0035215 44 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
peptidyl threonine modification GO:0018210 3 0.012
body morphogenesis GO:0010171 2 0.012
response to growth factor GO:0070848 31 0.011
dorsal closure GO:0007391 79 0.011
morphogenesis of a polarized epithelium GO:0001738 93 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
larval development GO:0002164 104 0.011
transmembrane transport GO:0055085 139 0.011
epithelial cell development GO:0002064 274 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
response to lipopolysaccharide GO:0032496 4 0.011
limb development GO:0060173 1 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
nitrogen compound transport GO:0071705 85 0.011
intracellular transport GO:0046907 228 0.011
growth GO:0040007 359 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
secretion by cell GO:0032940 101 0.011
protein complex biogenesis GO:0070271 201 0.011
oocyte axis specification GO:0007309 108 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
carbohydrate homeostasis GO:0033500 12 0.011
pole plasm mrna localization GO:0019094 49 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
peptidyl tyrosine modification GO:0018212 24 0.011
positive regulation of nervous system development GO:0051962 69 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.010
axonogenesis GO:0007409 290 0.010
response to ionizing radiation GO:0010212 32 0.010
protein modification by small protein removal GO:0070646 28 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
regulation of embryonic development GO:0045995 68 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
defense response to other organism GO:0098542 225 0.010
defense response to gram negative bacterium GO:0050829 94 0.010
protein secretion GO:0009306 45 0.010
histolysis GO:0007559 102 0.010
regulation of epidermal cell differentiation GO:0045604 3 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
salivary gland development GO:0007431 162 0.010
imaginal disc growth GO:0007446 37 0.010

moi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
disease of cellular proliferation DOID:14566 0 0.016
central nervous system disease DOID:331 0 0.013
nervous system disease DOID:863 0 0.013
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013