|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.429
|
Human |
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.369
|
|
|
|
dna conformation change
|
GO:0071103 |
105 |
0.294
|
Human |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.248
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.187
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.170
|
Human |
|
|
mrna splicing via spliceosome
|
GO:0000398 |
73 |
0.163
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.155
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.152
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.148
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.141
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.127
|
|
|
|
gene silencing
|
GO:0016458 |
138 |
0.126
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.126
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.112
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.107
|
Human |
|
|
heterocycle catabolic process
|
GO:0046700 |
166 |
0.107
|
|
|
|
mrna metabolic process
|
GO:0016071 |
124 |
0.099
|
|
|
|
regulation of alternative mrna splicing via spliceosome
|
GO:0000381 |
60 |
0.096
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
77 |
0.087
|
|
|
|
dna packaging
|
GO:0006323 |
91 |
0.078
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
72 |
0.078
|
Human |
|
|
cell death
|
GO:0008219 |
279 |
0.071
|
Human |
|
|
translation
|
GO:0006412 |
69 |
0.070
|
|
|
|
defense response
|
GO:0006952 |
300 |
0.065
|
|
|
|
immune response
|
GO:0006955 |
246 |
0.061
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.061
|
|
|
|
negative regulation of translation
|
GO:0017148 |
28 |
0.060
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.060
|
Human |
|
|
aromatic compound catabolic process
|
GO:0019439 |
166 |
0.059
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
69 |
0.059
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
128 |
0.058
|
|
|
|
chromosome organization
|
GO:0051276 |
360 |
0.056
|
Human |
|
|
alternative mrna splicing via spliceosome
|
GO:0000380 |
60 |
0.055
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.055
|
Human |
|
|
protein modification process
|
GO:0036211 |
438 |
0.049
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.048
|
Human |
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.047
|
|
|
|
oocyte development
|
GO:0048599 |
124 |
0.046
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.044
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.044
|
Human |
|
|
phagocytosis
|
GO:0006909 |
215 |
0.042
|
|
|
|
rna processing
|
GO:0006396 |
147 |
0.042
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.040
|
|
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.039
|
|
|
|
defense response to bacterium
|
GO:0042742 |
178 |
0.039
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
86 |
0.038
|
Human |
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.038
|
|
|
|
nuclear transport
|
GO:0051169 |
72 |
0.038
|
Human |
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.038
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
171 |
0.037
|
|
|
|
neurological system process
|
GO:0050877 |
358 |
0.037
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.036
|
Human |
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.036
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.035
|
|
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.035
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.035
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
73 |
0.035
|
|
|
|
regulation of translation
|
GO:0006417 |
56 |
0.033
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.033
|
|
|
|
chromatin silencing
|
GO:0006342 |
76 |
0.032
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.031
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
206 |
0.030
|
|
|
|
segmentation
|
GO:0035282 |
207 |
0.030
|
|
|
|
homeostatic process
|
GO:0042592 |
199 |
0.030
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.029
|
Worm |
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
75 |
0.029
|
|
|
|
muscle organ development
|
GO:0007517 |
127 |
0.029
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.028
|
|
|
|
multi organism behavior
|
GO:0051705 |
175 |
0.028
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.028
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
112 |
0.027
|
|
|
|
response to bacterium
|
GO:0009617 |
198 |
0.027
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.026
|
|
|
|
intracellular transport
|
GO:0046907 |
228 |
0.026
|
Human |
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.025
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.025
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
64 |
0.025
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.025
|
|
|
|
muscle attachment
|
GO:0016203 |
36 |
0.025
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.024
|
|
|
|
organelle fission
|
GO:0048285 |
340 |
0.024
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.024
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.024
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
293 |
0.023
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.023
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
201 |
0.022
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
168 |
0.022
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
165 |
0.022
|
|
|
|
death
|
GO:0016265 |
284 |
0.021
|
Human |
|
|
regulation of mrna metabolic process
|
GO:1903311 |
72 |
0.021
|
|
|
|
histone modification
|
GO:0016570 |
106 |
0.021
|
|
|
|
larval development
|
GO:0002164 |
104 |
0.021
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.020
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.020
|
|
|
|
regulation of cell shape
|
GO:0008360 |
113 |
0.019
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.019
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.019
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
117 |
0.019
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.019
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
109 |
0.018
|
|
|
|
proteolysis
|
GO:0006508 |
192 |
0.017
|
Human |
|
|
organic substance transport
|
GO:0071702 |
257 |
0.017
|
Human |
|
|
protein alkylation
|
GO:0008213 |
43 |
0.017
|
|
|
|
macromolecule methylation
|
GO:0043414 |
45 |
0.017
|
|
|
|
embryonic organ development
|
GO:0048568 |
50 |
0.017
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.017
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
119 |
0.017
|
|
|
|
rna splicing
|
GO:0008380 |
83 |
0.016
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.016
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.016
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.016
|
Human |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.016
|
|
|
|
locomotory behavior
|
GO:0007626 |
176 |
0.015
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.015
|
Human |
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.015
|
Human |
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.015
|
Human |
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.015
|
Human |
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.015
|
|
|
|
synapse assembly
|
GO:0007416 |
143 |
0.015
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
81 |
0.014
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
71 |
0.014
|
|
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.014
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
106 |
0.014
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
88 |
0.014
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
52 |
0.014
|
Human |
|
|
dna integrity checkpoint
|
GO:0031570 |
81 |
0.014
|
|
|
|
amine metabolic process
|
GO:0009308 |
12 |
0.014
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.014
|
|
|
|
mrna processing
|
GO:0006397 |
104 |
0.014
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.013
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
42 |
0.013
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
115 |
0.013
|
|
|
|
oocyte differentiation
|
GO:0009994 |
145 |
0.013
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
174 |
0.013
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
162 |
0.013
|
|
|
|
nucleosome organization
|
GO:0034728 |
59 |
0.013
|
Human |
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
38 |
0.013
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
220 |
0.013
|
Human |
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
31 |
0.012
|
|
|
|
cellular homeostasis
|
GO:0019725 |
80 |
0.012
|
|
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.012
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
120 |
0.012
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
130 |
0.012
|
Rat |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.012
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.012
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
294 |
0.012
|
|
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.011
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.011
|
Human |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
0 |
0.011
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.011
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
1 |
0.011
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.011
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
146 |
0.011
|
|
|
|
protein polymerization
|
GO:0051258 |
42 |
0.010
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
88 |
0.010
|
|
|
|
response to other organism
|
GO:0051707 |
293 |
0.010
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.010
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
59 |
0.010
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
136 |
0.010
|
|