Drosophila melanogaster

144 known processes

thr (Dmel_CG5785)

three rows

(Aliases: anch,CG5785,ana,Dmel\CG5785,THR,Thr)

thr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell division GO:0051301 248 0.931
digestive tract development GO:0048565 149 0.857
regulation of mitosis GO:0007088 56 0.846
nuclear migration GO:0007097 20 0.832
negative regulation of cellular metabolic process GO:0031324 382 0.826
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.754
regulation of cell cycle process GO:0010564 181 0.752
embryonic morphogenesis GO:0048598 206 0.663
establishment of nucleus localization GO:0040023 26 0.616
organelle fission GO:0048285 340 0.613
oocyte maturation GO:0001556 3 0.595
mitotic sister chromatid separation GO:0051306 30 0.565
mesoderm development GO:0007498 78 0.542
nuclear division GO:0000280 332 0.536
tube morphogenesis GO:0035239 191 0.532
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.522
cellular catabolic process GO:0044248 372 0.510
chromosome separation GO:0051304 42 0.494
negative regulation of mitotic cell cycle GO:0045930 109 0.431
negative regulation of cell cycle GO:0045786 116 0.401
negative regulation of cellular biosynthetic process GO:0031327 277 0.387
centrosome cycle GO:0007098 137 0.384
centrosome duplication GO:0051298 121 0.384
regulation of cell cycle GO:0051726 291 0.342
regulation of nuclear division GO:0051783 58 0.337
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.337
chromosome segregation GO:0007059 157 0.320
head involution GO:0008258 35 0.310
spindle organization GO:0007051 253 0.308
nucleus localization GO:0051647 34 0.306
regionalization GO:0003002 416 0.304
regulation of mitotic cell cycle GO:0007346 190 0.302
sister chromatid segregation GO:0000819 92 0.293
regulation of protein metabolic process GO:0051246 256 0.292
regulation of cell division GO:0051302 72 0.288
meiotic nuclear division GO:0007126 151 0.284
cellular protein localization GO:0034613 160 0.284
catabolic process GO:0009056 409 0.279
formation of primary germ layer GO:0001704 24 0.269
organelle localization GO:0051640 148 0.250
anterior posterior pattern specification GO:0009952 136 0.238
cellular protein modification process GO:0006464 438 0.229
axis specification GO:0009798 167 0.228
hindgut development GO:0061525 58 0.226
digestive tract morphogenesis GO:0048546 127 0.218
mitotic spindle organization GO:0007052 220 0.218
digestive system development GO:0055123 149 0.201
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.200
tube development GO:0035295 244 0.200
transcription from rna polymerase ii promoter GO:0006366 368 0.199
organic substance transport GO:0071702 257 0.196
response to oxygen containing compound GO:1901700 200 0.189
regulation of chromosome organization GO:0033044 64 0.186
microtubule anchoring GO:0034453 11 0.184
regulation of organelle organization GO:0033043 196 0.184
negative regulation of cell cycle process GO:0010948 109 0.178
negative regulation of cellular protein metabolic process GO:0032269 85 0.169
regulation of mitotic cell cycle phase transition GO:1901990 130 0.168
regulation of cell cycle phase transition GO:1901987 130 0.165
cellularization GO:0007349 90 0.163
organic substance catabolic process GO:1901575 308 0.159
regulation of mitotic sister chromatid separation GO:0010965 28 0.154
digestive tract mesoderm development GO:0007502 5 0.154
microtubule organizing center organization GO:0031023 168 0.149
cellular macromolecule localization GO:0070727 220 0.144
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.144
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.139
regulation of microtubule based process GO:0032886 49 0.135
anterior posterior axis specification GO:0009948 109 0.135
regulation of cell differentiation GO:0045595 302 0.133
regulation of embryonic development GO:0045995 68 0.132
regulation of cellular protein metabolic process GO:0032268 243 0.129
epithelial tube morphogenesis GO:0060562 88 0.128
dna metabolic process GO:0006259 227 0.125
regulation of microtubule cytoskeleton organization GO:0070507 41 0.123
mitotic cell cycle checkpoint GO:0007093 88 0.122
regulation of mitotic sister chromatid segregation GO:0033047 28 0.121
meiotic cell cycle GO:0051321 171 0.120
mitotic nuclear division GO:0007067 213 0.120
single organism intracellular transport GO:1902582 207 0.118
positive regulation of signal transduction GO:0009967 223 0.115
establishment of localization in cell GO:0051649 402 0.114
regulation of catabolic process GO:0009894 170 0.114
mitotic sister chromatid segregation GO:0000070 87 0.114
centrosome organization GO:0051297 163 0.108
protein localization GO:0008104 284 0.108
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.106
cell cycle checkpoint GO:0000075 95 0.105
maintenance of location GO:0051235 73 0.100
negative regulation of protein metabolic process GO:0051248 85 0.100
negative regulation of cell cycle phase transition GO:1901988 103 0.098
malpighian tubule development GO:0072002 64 0.098
mitotic dna integrity checkpoint GO:0044774 75 0.094
intracellular signal transduction GO:0035556 300 0.093
tissue morphogenesis GO:0048729 297 0.092
negative regulation of biosynthetic process GO:0009890 277 0.091
regulation of protein kinase activity GO:0045859 51 0.088
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.088
single organism catabolic process GO:0044712 228 0.088
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.087
regulation of phosphate metabolic process GO:0019220 210 0.085
mitotic cell cycle phase transition GO:0044772 138 0.085
carboxylic acid metabolic process GO:0019752 92 0.085
developmental maturation GO:0021700 172 0.082
blastoderm segmentation GO:0007350 159 0.081
negative regulation of gene expression GO:0010629 387 0.080
regulation of multicellular organismal development GO:2000026 414 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.078
regulation of cell morphogenesis GO:0022604 163 0.076
single organism cellular localization GO:1902580 180 0.076
dna packaging GO:0006323 91 0.075
regulation of cellular catabolic process GO:0031329 157 0.074
axon development GO:0061564 297 0.074
cellular macromolecule catabolic process GO:0044265 136 0.074
protein complex assembly GO:0006461 200 0.074
embryo development ending in birth or egg hatching GO:0009792 152 0.072
regulation of cellular protein catabolic process GO:1903362 44 0.071
regulation of transport GO:0051049 181 0.071
positive regulation of biosynthetic process GO:0009891 316 0.069
organic acid metabolic process GO:0006082 103 0.068
proteasomal protein catabolic process GO:0010498 59 0.067
protein modification process GO:0036211 438 0.066
oocyte anterior posterior axis specification GO:0007314 72 0.066
phosphorylation GO:0016310 294 0.065
cell maturation GO:0048469 144 0.065
maintenance of location in cell GO:0051651 28 0.065
attachment of spindle microtubules to kinetochore GO:0008608 5 0.065
positive regulation of nucleic acid templated transcription GO:1903508 266 0.065
g2 dna damage checkpoint GO:0031572 69 0.064
asymmetric cell division GO:0008356 37 0.064
metaphase anaphase transition of cell cycle GO:0044784 28 0.064
establishment of organelle localization GO:0051656 122 0.063
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.063
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.060
protein targeting GO:0006605 64 0.059
regulation of molecular function GO:0065009 217 0.059
organonitrogen compound metabolic process GO:1901564 318 0.058
negative regulation of phosphorus metabolic process GO:0010563 45 0.058
neuronal stem cell division GO:0036445 35 0.057
protein transport GO:0015031 155 0.057
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.056
oocyte differentiation GO:0009994 145 0.056
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.056
chromosome organization GO:0051276 360 0.055
maintenance of protein location in cell GO:0032507 26 0.055
mitotic g2 m transition checkpoint GO:0044818 70 0.053
body morphogenesis GO:0010171 2 0.053
negative regulation of rna metabolic process GO:0051253 251 0.052
central nervous system development GO:0007417 201 0.052
ubiquitin dependent protein catabolic process GO:0006511 78 0.052
positive regulation of macromolecule metabolic process GO:0010604 405 0.052
response to radiation GO:0009314 155 0.052
maternal determination of anterior posterior axis embryo GO:0008358 74 0.052
establishment of protein localization GO:0045184 163 0.050
regulation of proteasomal protein catabolic process GO:0061136 39 0.050
dendrite development GO:0016358 204 0.049
intracellular protein transport GO:0006886 104 0.049
negative regulation of cell division GO:0051782 17 0.048
renal system development GO:0072001 72 0.048
dna damage checkpoint GO:0000077 78 0.048
protein localization to organelle GO:0033365 82 0.048
chromosome condensation GO:0030261 41 0.048
axonogenesis GO:0007409 290 0.048
mesoderm morphogenesis GO:0048332 22 0.047
neuroblast division GO:0055057 35 0.047
axon guidance GO:0007411 233 0.046
anterior posterior axis specification embryo GO:0008595 103 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.046
cellular response to chemical stimulus GO:0070887 199 0.046
stem cell differentiation GO:0048863 117 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.044
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.044
regulation of mitotic spindle organization GO:0060236 9 0.043
determination of adult lifespan GO:0008340 137 0.043
regulation of cell shape GO:0008360 113 0.043
negative regulation of cell cell adhesion GO:0022408 8 0.043
negative regulation of phosphorylation GO:0042326 35 0.042
regulation of anatomical structure morphogenesis GO:0022603 242 0.042
nuclear import GO:0051170 51 0.042
cell migration GO:0016477 238 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.041
cellular protein complex assembly GO:0043623 71 0.041
intercellular bridge organization GO:0043063 14 0.039
spindle checkpoint GO:0031577 11 0.039
mitotic spindle checkpoint GO:0071174 11 0.039
protein complex biogenesis GO:0070271 201 0.039
embryonic pattern specification GO:0009880 174 0.038
regulation of localization GO:0032879 275 0.038
mesoderm formation GO:0001707 21 0.038
regulation of phosphorylation GO:0042325 147 0.037
proteolysis GO:0006508 192 0.037
neuroblast fate determination GO:0007400 12 0.036
dendrite morphogenesis GO:0048813 199 0.036
cell cycle phase transition GO:0044770 140 0.036
negative regulation of rna biosynthetic process GO:1902679 240 0.036
negative regulation of cellular component organization GO:0051129 108 0.035
dna integrity checkpoint GO:0031570 81 0.035
regulation of protein localization GO:0032880 76 0.035
meiotic cell cycle process GO:1903046 132 0.035
negative regulation of signal transduction GO:0009968 206 0.034
oxoacid metabolic process GO:0043436 103 0.033
hindgut morphogenesis GO:0007442 58 0.033
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.033
eggshell formation GO:0030703 105 0.032
mitotic g2 dna damage checkpoint GO:0007095 69 0.032
cytoplasmic transport GO:0016482 130 0.032
negative regulation of organelle organization GO:0010639 56 0.032
regulation of protein catabolic process GO:0042176 55 0.032
regulation of catalytic activity GO:0050790 185 0.032
cellular protein catabolic process GO:0044257 83 0.032
protein phosphorylation GO:0006468 169 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
taxis GO:0042330 304 0.031
regulation of phosphorus metabolic process GO:0051174 210 0.031
phagocytosis GO:0006909 215 0.031
aging GO:0007568 143 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.030
regulation of chromatin binding GO:0035561 3 0.030
negative regulation of proteolysis GO:0045861 31 0.030
mitotic spindle assembly checkpoint GO:0007094 11 0.030
embryonic axis specification GO:0000578 107 0.029
sensory organ morphogenesis GO:0090596 260 0.029
regulation of multi organism process GO:0043900 131 0.029
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.028
macromolecule catabolic process GO:0009057 161 0.028
dna conformation change GO:0071103 105 0.028
regulation of kinase activity GO:0043549 53 0.027
locomotory behavior GO:0007626 176 0.027
brain development GO:0007420 120 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
regulation of chromosome segregation GO:0051983 32 0.027
regulation of intracellular signal transduction GO:1902531 236 0.027
chorion containing eggshell formation GO:0007304 105 0.027
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.026
activation of rac gtpase activity GO:0032863 3 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
negative regulation of intracellular signal transduction GO:1902532 57 0.026
cellular amino acid metabolic process GO:0006520 61 0.025
protein catabolic process GO:0030163 101 0.025
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.025
wnt signaling pathway GO:0016055 98 0.025
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.025
regulation of cellular localization GO:0060341 136 0.024
positive regulation of transcription factor import into nucleus GO:0042993 19 0.024
endomembrane system organization GO:0010256 119 0.024
response to organic substance GO:0010033 284 0.024
growth GO:0040007 359 0.024
apoptotic process GO:0006915 159 0.024
regulation of response to stress GO:0080134 200 0.024
negative regulation of developmental process GO:0051093 201 0.024
positive regulation of gene expression GO:0010628 290 0.024
negative regulation of transcription dna templated GO:0045892 237 0.024
modification dependent protein catabolic process GO:0019941 78 0.024
mitotic dna damage checkpoint GO:0044773 74 0.024
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.023
cytoskeleton dependent intracellular transport GO:0030705 44 0.023
regulation of cytoskeleton organization GO:0051493 89 0.023
regulation of organ morphogenesis GO:2000027 78 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
negative regulation of phosphate metabolic process GO:0045936 45 0.022
mitotic spindle stabilization GO:0043148 6 0.022
positive regulation of mitotic cell cycle GO:0045931 34 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
response to wounding GO:0009611 94 0.022
cytoskeleton dependent cytokinesis GO:0061640 81 0.022
ovarian follicle cell development GO:0030707 248 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.022
oocyte development GO:0048599 124 0.022
developmental growth involved in morphogenesis GO:0060560 65 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.021
urogenital system development GO:0001655 72 0.021
reproductive system development GO:0061458 74 0.020
small molecule metabolic process GO:0044281 305 0.020
neuroblast fate commitment GO:0014017 19 0.020
macromolecular complex assembly GO:0065003 256 0.020
tripartite regional subdivision GO:0007351 103 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.020
single organism nuclear import GO:1902593 51 0.020
segmentation GO:0035282 207 0.020
regulation of response to external stimulus GO:0032101 115 0.020
eye morphogenesis GO:0048592 260 0.019
regulation of reproductive process GO:2000241 54 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
cardiovascular system development GO:0072358 82 0.019
regulation of cell cell adhesion GO:0022407 21 0.019
mapk cascade GO:0000165 107 0.019
chemical homeostasis GO:0048878 92 0.019
epithelial cell differentiation GO:0030855 322 0.019
compound eye development GO:0048749 307 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
positive regulation of cell cycle GO:0045787 43 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
malpighian tubule morphogenesis GO:0007443 44 0.019
dna replication GO:0006260 48 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
positive regulation of developmental process GO:0051094 143 0.018
regulation of nervous system development GO:0051960 248 0.018
single organism biosynthetic process GO:0044711 206 0.018
regulation of chromatin silencing GO:0031935 36 0.018
establishment of cell polarity GO:0030010 40 0.017
protein import GO:0017038 55 0.017
male gamete generation GO:0048232 201 0.017
intracellular transport GO:0046907 228 0.017
meiotic g2 mi transition GO:0008315 3 0.017
positive regulation of molecular function GO:0044093 136 0.017
reproductive structure development GO:0048608 74 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
pole cell formation GO:0007279 19 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
positive regulation of signaling GO:0023056 243 0.017
positive regulation of developmental growth GO:0048639 62 0.017
developmental programmed cell death GO:0010623 138 0.017
ras protein signal transduction GO:0007265 88 0.017
vesicle mediated transport GO:0016192 381 0.016
protein targeting to nucleus GO:0044744 51 0.016
adult locomotory behavior GO:0008344 76 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.016
gene silencing GO:0016458 138 0.016
regulation of cytoplasmic transport GO:1903649 47 0.016
mitotic cell cycle embryonic GO:0045448 38 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
heterocycle catabolic process GO:0046700 166 0.016
regulation of neuron differentiation GO:0045664 103 0.016
programmed cell death GO:0012501 257 0.016
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.016
response to endogenous stimulus GO:0009719 119 0.016
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.016
response to organic cyclic compound GO:0014070 89 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
regulation of sister chromatid cohesion GO:0007063 2 0.016
endocytosis GO:0006897 310 0.016
cell motility GO:0048870 251 0.016
response to sterol GO:0036314 34 0.016
cellular response to organic substance GO:0071310 132 0.015
positive regulation of cell communication GO:0010647 250 0.015
cellular amine metabolic process GO:0044106 12 0.015
developmental growth GO:0048589 280 0.015
actin filament based process GO:0030029 220 0.015
glial cell development GO:0021782 27 0.015
regulation of transferase activity GO:0051338 58 0.014
nuclear transport GO:0051169 72 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
medulla oblongata development GO:0021550 2 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
localization of cell GO:0051674 257 0.014
eye development GO:0001654 323 0.014
myofibril assembly GO:0030239 36 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cell death GO:0008219 279 0.014
protein localization to nucleus GO:0034504 55 0.014
forebrain development GO:0030900 2 0.014
adult behavior GO:0030534 137 0.014
positive regulation of cdc42 gtpase activity GO:0043089 2 0.013
antimicrobial humoral response GO:0019730 99 0.013
negative regulation of cellular catabolic process GO:0031330 34 0.013
positive regulation of nucleotide catabolic process GO:0030813 46 0.013
nucleotide catabolic process GO:0009166 109 0.013
cellular ketone metabolic process GO:0042180 24 0.013
chromosome movement towards spindle pole GO:0051305 4 0.013
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 13 0.013
appendage morphogenesis GO:0035107 397 0.013
negative regulation of cell communication GO:0010648 223 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
amine metabolic process GO:0009308 12 0.013
regulation of dna metabolic process GO:0051052 34 0.012
pole cell development GO:0007277 26 0.012
ovulation GO:0030728 4 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
stem cell development GO:0048864 79 0.012
cell cycle dna replication GO:0044786 23 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.012
spermatogenesis GO:0007283 200 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
epithelial cell development GO:0002064 274 0.012
renal tubule development GO:0061326 64 0.012
positive regulation of neuron differentiation GO:0045666 26 0.011
regulation of embryonic pattern specification GO:1902875 27 0.011
negative regulation of signaling GO:0023057 219 0.011
nucleotide metabolic process GO:0009117 161 0.011
regulation of cellular response to stress GO:0080135 89 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
negative regulation of transcription factor import into nucleus GO:0042992 4 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
asymmetric neuroblast division GO:0055059 33 0.011
branching morphogenesis of an epithelial tube GO:0048754 45 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
negative regulation of protein catabolic process GO:0042177 17 0.011
response to abiotic stimulus GO:0009628 341 0.010
regulation of multicellular organism growth GO:0040014 40 0.010
neuroblast proliferation GO:0007405 74 0.010
negative regulation of cell death GO:0060548 81 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
immune response GO:0006955 246 0.010
r7 cell differentiation GO:0045466 43 0.010
stem cell maintenance GO:0019827 67 0.010

thr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.067
disease of cellular proliferation DOID:14566 0 0.067
organ system cancer DOID:0050686 0 0.067
disease of anatomical entity DOID:7 0 0.021