Drosophila melanogaster

51 known processes

Klc (Dmel_CG5433)

Kinesin light chain

(Aliases: Dmel\CG5433,klc,KLC,DKLC,CG5433,kinesin)

Klc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell maturation GO:0048469 144 0.694
oocyte differentiation GO:0009994 145 0.628
axis specification GO:0009798 167 0.592
organelle assembly GO:0070925 198 0.590
regulation of cellular catabolic process GO:0031329 157 0.421
oocyte axis specification GO:0007309 108 0.374
synaptic transmission GO:0007268 288 0.303
Worm
protein localization GO:0008104 284 0.296
Rat
establishment of organelle localization GO:0051656 122 0.291
Worm
single organism intracellular transport GO:1902582 207 0.246
Mouse
oocyte construction GO:0007308 112 0.225
organic substance catabolic process GO:1901575 308 0.202
dna integrity checkpoint GO:0031570 81 0.192
response to biotic stimulus GO:0009607 294 0.186
oocyte development GO:0048599 124 0.185
regionalization GO:0003002 416 0.182
immune response GO:0006955 246 0.180
cellular catabolic process GO:0044248 372 0.175
cell cycle phase transition GO:0044770 140 0.164
defense response to gram negative bacterium GO:0050829 94 0.162
cellular nitrogen compound catabolic process GO:0044270 165 0.161
response to external biotic stimulus GO:0043207 293 0.156
regulation of catabolic process GO:0009894 170 0.149
purine nucleotide catabolic process GO:0006195 109 0.148
establishment or maintenance of cell polarity GO:0007163 167 0.148
anterior posterior axis specification embryo GO:0008595 103 0.144
cellular protein complex assembly GO:0043623 71 0.138
Fly
oocyte dorsal ventral axis specification GO:0007310 34 0.138
microtubule based transport GO:0010970 42 0.135
Mouse
response to bacterium GO:0009617 198 0.134
vesicle mediated transport GO:0016192 381 0.133
Worm
nucleoside catabolic process GO:0009164 112 0.132
organonitrogen compound catabolic process GO:1901565 128 0.132
purine ribonucleoside catabolic process GO:0046130 112 0.132
ribonucleoside catabolic process GO:0042454 112 0.127
single organism cellular localization GO:1902580 180 0.127
Worm
ribonucleoside triphosphate catabolic process GO:0009203 108 0.118
cytoskeleton dependent intracellular transport GO:0030705 44 0.113
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.113
mitotic cell cycle checkpoint GO:0007093 88 0.113
cellular macromolecular complex assembly GO:0034622 153 0.112
Fly
establishment of nucleus localization GO:0040023 26 0.103
actin filament based process GO:0030029 220 0.101
regulation of molecular function GO:0065009 217 0.099
positive regulation of cellular catabolic process GO:0031331 95 0.098
catabolic process GO:0009056 409 0.097
regulation of multicellular organismal development GO:2000026 414 0.097
positive regulation of catabolic process GO:0009896 105 0.096
small molecule metabolic process GO:0044281 305 0.090
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.089
epithelial cell differentiation GO:0030855 322 0.088
establishment of vesicle localization GO:0051650 51 0.088
Worm
protein ubiquitination GO:0016567 70 0.086
immune system process GO:0002376 347 0.086
organic cyclic compound catabolic process GO:1901361 168 0.084
actin cytoskeleton organization GO:0030036 206 0.082
biological adhesion GO:0022610 138 0.081
regulation of cell differentiation GO:0045595 302 0.080
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.080
defense response to other organism GO:0098542 225 0.080
positive regulation of nucleoside metabolic process GO:0045979 47 0.078
single organism catabolic process GO:0044712 228 0.078
heterocycle catabolic process GO:0046700 166 0.077
purine nucleoside catabolic process GO:0006152 112 0.077
aromatic compound catabolic process GO:0019439 166 0.077
microtubule based movement GO:0007018 51 0.076
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.075
protein modification by small protein conjugation or removal GO:0070647 106 0.075
gtp catabolic process GO:0006184 72 0.074
spindle assembly GO:0051225 80 0.073
negative regulation of mitotic cell cycle GO:0045930 109 0.071
response to other organism GO:0051707 293 0.070
mitotic dna damage checkpoint GO:0044773 74 0.069
regulation of anatomical structure size GO:0090066 163 0.069
negative regulation of cell cycle process GO:0010948 109 0.068
dorsal ventral pattern formation GO:0009953 133 0.067
larval development GO:0002164 104 0.067
Worm
organonitrogen compound metabolic process GO:1901564 318 0.067
purine ribonucleotide catabolic process GO:0009154 109 0.066
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.064
lateral inhibition GO:0046331 206 0.061
regulation of tube size GO:0035150 46 0.059
establishment of cell polarity GO:0030010 40 0.059
nucleus localization GO:0051647 34 0.058
regulation of synapse organization GO:0050807 110 0.057
axonogenesis GO:0007409 290 0.057
Worm
defense response GO:0006952 300 0.056
ribose phosphate metabolic process GO:0019693 145 0.055
nucleoside phosphate catabolic process GO:1901292 110 0.053
innate immune response GO:0045087 144 0.053
purine nucleoside triphosphate catabolic process GO:0009146 108 0.052
purine nucleoside triphosphate metabolic process GO:0009144 119 0.052
single organism behavior GO:0044708 391 0.051
Fly
axon cargo transport GO:0008088 29 0.051
Mouse
cellular macromolecule localization GO:0070727 220 0.050
Rat
purine ribonucleoside metabolic process GO:0046128 127 0.050
neurological system process GO:0050877 358 0.050
negative regulation of cell cycle phase transition GO:1901988 103 0.050
nucleobase containing compound catabolic process GO:0034655 165 0.048
regulation of defense response GO:0031347 102 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.048
nuclear division GO:0000280 332 0.047
Worm
glycosyl compound catabolic process GO:1901658 112 0.046
defense response to bacterium GO:0042742 178 0.045
mitotic g2 m transition checkpoint GO:0044818 70 0.045
developmental maturation GO:0021700 172 0.045
nuclear migration GO:0007097 20 0.045
muscle cell development GO:0055001 50 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.045
cell cycle checkpoint GO:0000075 95 0.044
endosomal transport GO:0016197 44 0.043
nucleoside triphosphate catabolic process GO:0009143 108 0.043
regulation of hydrolase activity GO:0051336 97 0.043
intracellular signal transduction GO:0035556 300 0.043
purine nucleotide metabolic process GO:0006163 146 0.041
regulation of cellular component biogenesis GO:0044087 201 0.041
regulation of nucleoside metabolic process GO:0009118 50 0.040
regulation of nucleotide catabolic process GO:0030811 48 0.040
purine containing compound catabolic process GO:0072523 112 0.040
mitotic g2 dna damage checkpoint GO:0007095 69 0.038
pronuclear migration GO:0035046 4 0.038
cell death GO:0008219 279 0.038
positive regulation of catalytic activity GO:0043085 118 0.038
nucleotide metabolic process GO:0009117 161 0.037
positive regulation of hydrolase activity GO:0051345 78 0.037
organic substance transport GO:0071702 257 0.037
Rat
response to abiotic stimulus GO:0009628 341 0.036
Fly
nucleotide catabolic process GO:0009166 109 0.036
guanosine containing compound catabolic process GO:1901069 74 0.035
endocytic recycling GO:0032456 13 0.035
guanosine containing compound metabolic process GO:1901068 74 0.035
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
ribonucleoside triphosphate metabolic process GO:0009199 119 0.034
dendrite development GO:0016358 204 0.034
carbohydrate derivative catabolic process GO:1901136 118 0.033
g2 dna damage checkpoint GO:0031572 69 0.033
protein modification by small protein conjugation GO:0032446 79 0.033
regulation of cell cycle GO:0051726 291 0.031
regulation of catalytic activity GO:0050790 185 0.031
ribonucleotide catabolic process GO:0009261 109 0.030
intracellular transport GO:0046907 228 0.030
Mouse Rat
cellular component assembly involved in morphogenesis GO:0010927 151 0.030
synapse organization GO:0050808 196 0.030
columnar cuboidal epithelial cell development GO:0002066 249 0.029
regulation of localization GO:0032879 275 0.029
cellular protein localization GO:0034613 160 0.028
Rat
regulation of cell cycle phase transition GO:1901987 130 0.028
maintenance of protein location GO:0045185 28 0.028
regulation of intracellular signal transduction GO:1902531 236 0.028
negative regulation of cell cycle GO:0045786 116 0.027
purine nucleoside metabolic process GO:0042278 127 0.027
female meiotic division GO:0007143 70 0.027
Worm
gtp metabolic process GO:0046039 72 0.027
regulation of purine nucleotide catabolic process GO:0033121 48 0.027
organophosphate catabolic process GO:0046434 112 0.027
single organism biosynthetic process GO:0044711 206 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.027
ribonucleoside metabolic process GO:0009119 127 0.027
salivary gland histolysis GO:0035070 88 0.026
regulation of cytoskeleton organization GO:0051493 89 0.026
purine ribonucleotide metabolic process GO:0009150 145 0.026
mitotic spindle organization GO:0007052 220 0.026
response to organonitrogen compound GO:0010243 75 0.025
endomembrane system organization GO:0010256 119 0.025
embryonic pattern specification GO:0009880 174 0.024
dna damage checkpoint GO:0000077 78 0.024
regulation of transport GO:0051049 181 0.024
cellularization GO:0007349 90 0.024
purine containing compound metabolic process GO:0072521 155 0.024
wnt signaling pathway GO:0016055 98 0.024
negative regulation of developmental process GO:0051093 201 0.024
regulation of protein localization GO:0032880 76 0.024
segmentation GO:0035282 207 0.024
positive regulation of nucleotide catabolic process GO:0030813 46 0.023
organelle fission GO:0048285 340 0.023
Worm
positive regulation of nucleotide metabolic process GO:0045981 55 0.023
single fertilization GO:0007338 24 0.023
axon guidance GO:0007411 233 0.023
single organism membrane organization GO:0044802 93 0.023
establishment of rna localization GO:0051236 47 0.022
glycosyl compound metabolic process GO:1901657 127 0.022
negative regulation of neuron death GO:1901215 18 0.022
regulation of nucleotide metabolic process GO:0006140 62 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.021
molting cycle GO:0042303 56 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
mitotic dna integrity checkpoint GO:0044774 75 0.021
regulation of gtpase activity GO:0043087 44 0.021
positive regulation of molecular function GO:0044093 136 0.020
regulation of purine nucleotide metabolic process GO:1900542 62 0.020
rna localization GO:0006403 115 0.020
regulation of growth GO:0040008 233 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
protein modification process GO:0036211 438 0.020
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
nucleoside metabolic process GO:0009116 127 0.020
growth GO:0040007 359 0.020
Worm
regulation of synapse structure and activity GO:0050803 128 0.019
membrane organization GO:0061024 112 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
cell migration GO:0016477 238 0.019
stem cell differentiation GO:0048863 117 0.019
macromolecule catabolic process GO:0009057 161 0.019
dendrite morphogenesis GO:0048813 199 0.019
protein polymerization GO:0051258 42 0.019
regulation of cell development GO:0060284 215 0.019
regulation of gtp catabolic process GO:0033124 44 0.019
lipid localization GO:0010876 54 0.018
skeletal muscle organ development GO:0060538 48 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
cellular protein modification process GO:0006464 438 0.018
ras protein signal transduction GO:0007265 88 0.017
microtubule polymerization or depolymerization GO:0031109 39 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
blastoderm segmentation GO:0007350 159 0.017
regulation of hemocyte proliferation GO:0035206 37 0.017
developmental growth GO:0048589 280 0.017
Worm
positive regulation of gtp catabolic process GO:0033126 43 0.017
muscle structure development GO:0061061 224 0.017
regulation of cell cycle process GO:0010564 181 0.017
ribonucleoside monophosphate catabolic process GO:0009158 39 0.017
aging GO:0007568 143 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
retina development in camera type eye GO:0060041 4 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
regulation of innate immune response GO:0045088 71 0.016
cell adhesion GO:0007155 136 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
maintenance of location GO:0051235 73 0.016
regulation of cellular response to stress GO:0080135 89 0.016
multicellular organismal aging GO:0010259 140 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
programmed cell death GO:0012501 257 0.016
positive regulation of signaling GO:0023056 243 0.016
microtubule anchoring GO:0034453 11 0.016
regulation of wnt signaling pathway GO:0030111 68 0.016
gene silencing GO:0016458 138 0.015
ovarian follicle cell development GO:0030707 248 0.015
developmental programmed cell death GO:0010623 138 0.015
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.015
regulation of blood circulation GO:1903522 21 0.015
establishment of localization in cell GO:0051649 402 0.015
Mouse Rat Worm
multi organism behavior GO:0051705 175 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
cellular ketone metabolic process GO:0042180 24 0.014
cell growth GO:0016049 108 0.014
Worm
regulation of phosphorus metabolic process GO:0051174 210 0.014
cellular response to radiation GO:0071478 52 0.013
plasma membrane organization GO:0007009 26 0.013
organophosphate metabolic process GO:0019637 195 0.013
maintenance of location in cell GO:0051651 28 0.013
protein transmembrane transport GO:0071806 4 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
adult behavior GO:0030534 137 0.013
Fly
dorsal ventral axis specification GO:0009950 66 0.013
protein transport GO:0015031 155 0.013
Rat
nucleoside monophosphate catabolic process GO:0009125 39 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
negative regulation of cytoskeleton organization GO:0051494 30 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
ovarian follicle cell migration GO:0007297 121 0.012
protein localization to organelle GO:0033365 82 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
rho protein signal transduction GO:0007266 14 0.012
sister chromatid segregation GO:0000819 92 0.012
actin filament polymerization GO:0030041 27 0.012
heart morphogenesis GO:0003007 32 0.012
ameboidal type cell migration GO:0001667 151 0.012
spindle assembly involved in mitosis GO:0090307 50 0.011
proteolysis GO:0006508 192 0.011
negative regulation of cell death GO:0060548 81 0.011
response to temperature stimulus GO:0009266 106 0.011
death GO:0016265 284 0.011
positive regulation of gtpase activity GO:0043547 43 0.011
regulation of response to stress GO:0080134 200 0.011
fertilization GO:0009566 26 0.011
regulation of ras gtpase activity GO:0032318 38 0.011
translation GO:0006412 69 0.011
homeostatic process GO:0042592 199 0.011
positive regulation of chromatin modification GO:1903310 17 0.010
endocytosis GO:0006897 310 0.010
protein catabolic process GO:0030163 101 0.010
regulation of cell size GO:0008361 63 0.010
epithelium migration GO:0090132 148 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
eye development GO:0001654 323 0.010
atp catabolic process GO:0006200 38 0.010
positive regulation of axonogenesis GO:0050772 2 0.010
regulation of organelle organization GO:0033043 196 0.010

Klc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.086
nervous system disease DOID:863 0 0.034