|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.902
|
|
|
|
immune response
|
GO:0006955 |
246 |
0.829
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
43 |
0.691
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
2 |
0.632
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.620
|
|
|
|
myoblast fusion
|
GO:0007520 |
43 |
0.620
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.620
|
Fly |
|
|
myotube differentiation
|
GO:0014902 |
46 |
0.587
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
220 |
0.570
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.567
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.520
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.513
|
Worm |
|
|
muscle attachment
|
GO:0016203 |
36 |
0.509
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.489
|
|
|
|
tube development
|
GO:0035295 |
244 |
0.486
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
90 |
0.469
|
Mouse Worm |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.450
|
|
|
|
organic substance transport
|
GO:0071702 |
257 |
0.449
|
Mouse |
|
|
apoptotic process
|
GO:0006915 |
159 |
0.408
|
Mouse |
|
|
kidney morphogenesis
|
GO:0060993 |
3 |
0.402
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.400
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.391
|
Worm |
|
|
muscle structure development
|
GO:0061061 |
224 |
0.387
|
|
|
|
growth
|
GO:0040007 |
359 |
0.385
|
Worm |
|
|
defense response
|
GO:0006952 |
300 |
0.378
|
|
|
|
cell adhesion
|
GO:0007155 |
136 |
0.374
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
68 |
0.371
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.364
|
|
|
|
regulation of growth
|
GO:0040008 |
233 |
0.363
|
Worm |
|
|
biological adhesion
|
GO:0022610 |
138 |
0.355
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
103 |
0.334
|
Mouse Worm |
|
|
cellular response to organic substance
|
GO:0071310 |
132 |
0.332
|
|
|
|
body morphogenesis
|
GO:0010171 |
2 |
0.328
|
Worm |
|
|
response to organic substance
|
GO:0010033 |
284 |
0.324
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.312
|
Mouse |
|
|
cell proliferation
|
GO:0008283 |
299 |
0.311
|
Worm |
|
|
cell motility
|
GO:0048870 |
251 |
0.302
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.299
|
Worm |
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.293
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.287
|
Mouse |
|
|
homeostatic process
|
GO:0042592 |
199 |
0.273
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.271
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.270
|
Human |
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.268
|
Worm |
|
|
cellular response to oxidative stress
|
GO:0034599 |
28 |
0.262
|
|
|
|
organelle assembly
|
GO:0070925 |
198 |
0.260
|
Worm |
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.258
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
201 |
0.256
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.252
|
Mouse |
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.252
|
|
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.250
|
|
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.248
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
44 |
0.243
|
|
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.240
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.240
|
|
|
|
response to wounding
|
GO:0009611 |
94 |
0.237
|
|
|
|
nuclear transport
|
GO:0051169 |
72 |
0.234
|
Mouse |
|
|
eye development
|
GO:0001654 |
323 |
0.233
|
Fly |
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.232
|
|
|
|
muscle organ development
|
GO:0007517 |
127 |
0.229
|
|
|
|
actin filament based process
|
GO:0030029 |
220 |
0.224
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
21 |
0.223
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.221
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.219
|
|
|
|
death
|
GO:0016265 |
284 |
0.216
|
Mouse |
|
|
catabolic process
|
GO:0009056 |
409 |
0.215
|
Worm |
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.211
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
116 |
0.209
|
Worm |
|
|
wnt signaling pathway
|
GO:0016055 |
98 |
0.202
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.196
|
Mouse |
|
|
cell migration
|
GO:0016477 |
238 |
0.195
|
Mouse |
|
|
response to temperature stimulus
|
GO:0009266 |
106 |
0.194
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.193
|
|
|
|
response to inorganic substance
|
GO:0010035 |
44 |
0.189
|
|
|
|
protein catabolic process
|
GO:0030163 |
101 |
0.188
|
Worm |
|
|
innate immune response
|
GO:0045087 |
144 |
0.185
|
|
|
|
outflow tract morphogenesis
|
GO:0003151 |
4 |
0.185
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.184
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
97 |
0.183
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.182
|
Mouse |
|
|
response to reactive oxygen species
|
GO:0000302 |
24 |
0.180
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.179
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.178
|
Worm |
|
|
regulation of cell shape
|
GO:0008360 |
113 |
0.176
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.172
|
Human Worm |
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.170
|
Worm |
|
|
actin cytoskeleton organization
|
GO:0030036 |
206 |
0.168
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
90 |
0.166
|
|
|
|
single organism nuclear import
|
GO:1902593 |
51 |
0.164
|
Mouse |
|
|
molting cycle chitin based cuticle
|
GO:0007591 |
56 |
0.159
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
8 |
0.158
|
|
|
|
establishment of protein localization
|
GO:0045184 |
163 |
0.157
|
Mouse |
|
|
appendage development
|
GO:0048736 |
401 |
0.156
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
151 |
0.154
|
Worm |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
79 |
0.154
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
6 |
0.153
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
45 |
0.153
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
130 |
0.151
|
Mouse |
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.150
|
|
|
|
nuclear import
|
GO:0051170 |
51 |
0.150
|
Mouse |
|
|
response to drug
|
GO:0042493 |
17 |
0.148
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.142
|
Mouse Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.141
|
|
|
|
developmental growth
|
GO:0048589 |
280 |
0.140
|
Worm |
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.137
|
|
|
|
extracellular matrix assembly
|
GO:0085029 |
13 |
0.136
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
62 |
0.136
|
Worm |
|
|
proteolysis
|
GO:0006508 |
192 |
0.134
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.134
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
38 |
0.133
|
|
|
|
synapse assembly
|
GO:0007416 |
143 |
0.133
|
|
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.132
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
72 |
0.130
|
Mouse |
|
|
dendrite morphogenesis
|
GO:0048813 |
199 |
0.128
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.128
|
|
|
|
extracellular structure organization
|
GO:0043062 |
46 |
0.127
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.126
|
Human |
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.125
|
Mouse |
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.121
|
Worm |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
80 |
0.121
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.120
|
Mouse |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.119
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.118
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
119 |
0.117
|
|
|
|
muscle cell development
|
GO:0055001 |
50 |
0.117
|
Mouse Worm |
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.114
|
|
|
|
protein localization to organelle
|
GO:0033365 |
82 |
0.114
|
Mouse Fly |
|
|
nuclear division
|
GO:0000280 |
332 |
0.114
|
Worm |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.113
|
Mouse |
|
|
positive regulation of growth
|
GO:0045927 |
75 |
0.111
|
Worm |
|
|
response to metal ion
|
GO:0010038 |
23 |
0.109
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.107
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.105
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
75 |
0.105
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.105
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.105
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
3 |
0.105
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.104
|
Worm |
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.103
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
47 |
0.101
|
Worm |
|
|
respiratory system development
|
GO:0060541 |
213 |
0.100
|
Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
47 |
0.100
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
6 |
0.099
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.097
|
|
|
|
neuron projection guidance
|
GO:0097485 |
241 |
0.096
|
|
|
|
somatic muscle development
|
GO:0007525 |
66 |
0.096
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
36 |
0.095
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
48 |
0.093
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
3 |
0.093
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
207 |
0.093
|
Mouse |
|
|
intracellular transport
|
GO:0046907 |
228 |
0.093
|
Mouse |
|
|
regulation of localization
|
GO:0032879 |
275 |
0.092
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
24 |
0.092
|
|
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.092
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.090
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
62 |
0.090
|
Mouse |
|
|
cell aging
|
GO:0007569 |
2 |
0.089
|
Human Zebrafish Fly |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.088
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.088
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.088
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.087
|
|
|
|
lamellipodium organization
|
GO:0097581 |
21 |
0.087
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
45 |
0.087
|
Fly |
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.086
|
|
|
|
cellular protein localization
|
GO:0034613 |
160 |
0.083
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
108 |
0.083
|
Mouse |
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.082
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
47 |
0.081
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.081
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.081
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
163 |
0.081
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
200 |
0.081
|
|
|
|
atp metabolic process
|
GO:0046034 |
49 |
0.080
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
55 |
0.080
|
Mouse Fly |
|
|
response to extracellular stimulus
|
GO:0009991 |
116 |
0.080
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.079
|
Mouse |
|
|
pupal development
|
GO:0035209 |
11 |
0.079
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
2 |
0.079
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.079
|
Mouse |
|
|
protein targeting to nucleus
|
GO:0044744 |
51 |
0.078
|
Mouse |
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
28 |
0.078
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
206 |
0.078
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.076
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
109 |
0.076
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
88 |
0.075
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
157 |
0.074
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.074
|
Mouse |
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.074
|
Mouse |
|
|
kidney development
|
GO:0001822 |
3 |
0.074
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.073
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.073
|
|
|
|
dendrite development
|
GO:0016358 |
204 |
0.072
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
112 |
0.072
|
|
|
|
cuticle pigmentation
|
GO:0048067 |
22 |
0.071
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
42 |
0.071
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
89 |
0.071
|
|
|
|
protein import into nucleus
|
GO:0006606 |
51 |
0.070
|
Mouse |
|
|
wound healing
|
GO:0042060 |
75 |
0.070
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.070
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
122 |
0.070
|
|
|
|
localization of cell
|
GO:0051674 |
257 |
0.069
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
69 |
0.069
|
|
|
|
response to virus
|
GO:0009615 |
28 |
0.069
|
|
|
|
notch signaling pathway
|
GO:0007219 |
120 |
0.068
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
83 |
0.068
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
166 |
0.067
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
17 |
0.067
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.067
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
44 |
0.066
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
89 |
0.066
|
|
|
|
response to toxic substance
|
GO:0009636 |
22 |
0.065
|
|
|
|
cellular homeostasis
|
GO:0019725 |
80 |
0.065
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
3 |
0.065
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.065
|
Mouse |
|
|
regulation of synapse assembly
|
GO:0051963 |
94 |
0.065
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
127 |
0.064
|
|
|
|
myofibril assembly
|
GO:0030239 |
36 |
0.064
|
Worm |
|
|
striated muscle cell development
|
GO:0055002 |
50 |
0.063
|
Mouse Worm |
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.062
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
18 |
0.062
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.062
|
Worm |
|
|
nephron tubule development
|
GO:0072080 |
3 |
0.062
|
|
|
|
single organism catabolic process
|
GO:0044712 |
228 |
0.062
|
|
|
|
circulatory system process
|
GO:0003013 |
37 |
0.060
|
Zebrafish |
|
|
aging
|
GO:0007568 |
143 |
0.059
|
Human Zebrafish Worm Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
93 |
0.059
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.058
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
38 |
0.058
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
88 |
0.057
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
293 |
0.057
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
119 |
0.057
|
|
|
|
response to other organism
|
GO:0051707 |
293 |
0.056
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
213 |
0.056
|
Worm |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
130 |
0.056
|
|
|
|
heart contraction
|
GO:0060047 |
26 |
0.056
|
Zebrafish |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.056
|
|
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.056
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
116 |
0.056
|
|
|
|
response to oxidative stress
|
GO:0006979 |
86 |
0.056
|
|
|
|
myotube cell development
|
GO:0014904 |
3 |
0.056
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
25 |
0.056
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.055
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.055
|
Mouse |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.055
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
146 |
0.054
|
|
|
|
basement membrane organization
|
GO:0071711 |
10 |
0.054
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.054
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
94 |
0.054
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.053
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
3 |
0.053
|
|
|
|
response to lipid
|
GO:0033993 |
38 |
0.053
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
4 |
0.053
|
|
|
|
mapk cascade
|
GO:0000165 |
107 |
0.053
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
8 |
0.052
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
163 |
0.052
|
|
|
|
peptide metabolic process
|
GO:0006518 |
80 |
0.052
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.052
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
3 |
0.051
|
Worm |
|
|
cation homeostasis
|
GO:0055080 |
51 |
0.051
|
|
|
|
sensory perception
|
GO:0007600 |
196 |
0.051
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
3 |
0.051
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
58 |
0.050
|
Human |
|
|
negative regulation of immune system process
|
GO:0002683 |
50 |
0.050
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
87 |
0.049
|
|
|
|
actin filament organization
|
GO:0007015 |
126 |
0.049
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
42 |
0.049
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
127 |
0.049
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
83 |
0.049
|
|
|
|
endosomal transport
|
GO:0016197 |
44 |
0.048
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
45 |
0.047
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
105 |
0.047
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
112 |
0.047
|
|
|
|
regulation of myoblast fusion
|
GO:1901739 |
6 |
0.047
|
|
|
|
cognition
|
GO:0050890 |
141 |
0.046
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.046
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
127 |
0.046
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
83 |
0.046
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
109 |
0.046
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
94 |
0.046
|
|
|
|
single organism cellular localization
|
GO:1902580 |
180 |
0.045
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.045
|
|
|
|
ion homeostasis
|
GO:0050801 |
55 |
0.045
|
|
|
|
regulation of locomotion
|
GO:0040012 |
42 |
0.044
|
Mouse |
|
|
response to organophosphorus
|
GO:0046683 |
2 |
0.044
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
139 |
0.044
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
127 |
0.043
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
116 |
0.043
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.043
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.042
|
|
|
|
response to hormone
|
GO:0009725 |
45 |
0.042
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
118 |
0.042
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.042
|
|
|
|
protein targeting
|
GO:0006605 |
64 |
0.041
|
Mouse |
|
|
sarcomere organization
|
GO:0045214 |
26 |
0.041
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
92 |
0.041
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
130 |
0.041
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.041
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.041
|
|
|
|
response to nutrient levels
|
GO:0031667 |
114 |
0.041
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.041
|
|
|
|
phagocytosis
|
GO:0006909 |
215 |
0.041
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.040
|
|
|
|
digestive system development
|
GO:0055123 |
149 |
0.040
|
Fly |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
45 |
0.040
|
Fly |
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.040
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
28 |
0.040
|
|
|
|
gastrulation
|
GO:0007369 |
70 |
0.039
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
136 |
0.039
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
112 |
0.039
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
1 |
0.039
|
|
|
|
learning
|
GO:0007612 |
75 |
0.039
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
62 |
0.039
|
|
|
|
response to radiation
|
GO:0009314 |
155 |
0.039
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.039
|
Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
39 |
0.039
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
165 |
0.039
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
89 |
0.038
|
|
|
|
chemical homeostasis
|
GO:0048878 |
92 |
0.038
|
|
|
|
cellular response to peptide
|
GO:1901653 |
28 |
0.038
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.038
|
|
|
|
leg disc development
|
GO:0035218 |
92 |
0.038
|
|
|
|
protein transport
|
GO:0015031 |
155 |
0.037
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
22 |
0.037
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
39 |
0.037
|
|
|
|
taxis
|
GO:0042330 |
304 |
0.036
|
|
|
|
protein import
|
GO:0017038 |
55 |
0.036
|
Mouse |
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.036
|
|
|
|
muscle system process
|
GO:0003012 |
21 |
0.036
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
110 |
0.036
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
139 |
0.036
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
149 |
0.036
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
23 |
0.035
|
|
|
|
blood circulation
|
GO:0008015 |
26 |
0.035
|
Zebrafish |
|
|
secondary metabolic process
|
GO:0019748 |
75 |
0.035
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
145 |
0.035
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.035
|
Fly |
|
|
organelle fission
|
GO:0048285 |
340 |
0.035
|
Worm |
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.035
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
108 |
0.035
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
64 |
0.034
|
|
|
|
response to bacterium
|
GO:0009617 |
198 |
0.034
|
|
|
|
connective tissue development
|
GO:0061448 |
3 |
0.034
|
|
|
|
ion transport
|
GO:0006811 |
145 |
0.034
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
14 |
0.034
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
145 |
0.033
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
168 |
0.032
|
|
|
|
regionalization
|
GO:0003002 |
416 |
0.032
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
97 |
0.032
|
|
|
|
regulation of lamellipodium organization
|
GO:1902743 |
15 |
0.032
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
35 |
0.032
|
|
|
|
stem cell development
|
GO:0048864 |
79 |
0.032
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
108 |
0.032
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
1 |
0.032
|
|
|
|
neuronal action potential
|
GO:0019228 |
10 |
0.032
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.032
|
|
|
|
defense response to bacterium
|
GO:0042742 |
178 |
0.032
|
|
|
|
response to purine containing compound
|
GO:0014074 |
12 |
0.031
|
|
|
|
response to growth factor
|
GO:0070848 |
31 |
0.031
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
9 |
0.031
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
3 |
0.031
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
44 |
0.031
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
27 |
0.031
|
|
|
|
endoderm formation
|
GO:0001706 |
3 |
0.031
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
95 |
0.031
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.031
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
62 |
0.030
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.030
|
Mouse |
|
|
metal ion transport
|
GO:0030001 |
74 |
0.030
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
15 |
0.030
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
112 |
0.030
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
47 |
0.030
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
3 |
0.030
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
112 |
0.030
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
28 |
0.029
|
Human |
|
|
oxoacid metabolic process
|
GO:0043436 |
103 |
0.029
|
|
|
|
response to heat
|
GO:0009408 |
63 |
0.029
|
|
|
|
response to hypoxia
|
GO:0001666 |
53 |
0.029
|
Human |
|
|
immune system development
|
GO:0002520 |
57 |
0.029
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
78 |
0.029
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.029
|
|
|
|
camera type eye development
|
GO:0043010 |
4 |
0.029
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
43 |
0.029
|
|
|
|
reproductive structure development
|
GO:0048608 |
74 |
0.029
|
Worm Fly |
|
|
chemotaxis
|
GO:0006935 |
249 |
0.029
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
92 |
0.029
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
79 |
0.029
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.028
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.028
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.028
|
|
|
|
circulatory system development
|
GO:0072359 |
82 |
0.028
|
Mouse |
|
|
nephron epithelium development
|
GO:0072009 |
3 |
0.028
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.028
|
|
|
|
toxin metabolic process
|
GO:0009404 |
2 |
0.028
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
119 |
0.028
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
78 |
0.027
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
127 |
0.027
|
|
|
|
molting cycle process
|
GO:0022404 |
29 |
0.027
|
|
|
|
kidney epithelium development
|
GO:0072073 |
3 |
0.027
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
92 |
0.027
|
|
|
|
regulation of translation
|
GO:0006417 |
56 |
0.027
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
108 |
0.027
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
21 |
0.027
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
109 |
0.026
|
|
|
|
circadian behavior
|
GO:0048512 |
76 |
0.026
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
2 |
0.026
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
27 |
0.026
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
30 |
0.026
|
|
|
|
cation transport
|
GO:0006812 |
110 |
0.026
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
72 |
0.026
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.025
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
51 |
0.025
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
108 |
0.025
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
120 |
0.025
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
136 |
0.025
|
Mouse |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.025
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
104 |
0.025
|
Mouse |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
2 |
0.025
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
32 |
0.025
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
28 |
0.025
|
|
|
|
salivary gland development
|
GO:0007431 |
162 |
0.024
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
30 |
0.024
|
|
|
|
developmental maturation
|
GO:0021700 |
172 |
0.024
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
51 |
0.024
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
48 |
0.024
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
16 |
0.024
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
16 |
0.024
|
|
|
|
forebrain development
|
GO:0030900 |
2 |
0.024
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
61 |
0.024
|
|
|
|
gonad development
|
GO:0008406 |
50 |
0.024
|
Worm Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
112 |
0.023
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
29 |
0.023
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
11 |
0.023
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
18 |
0.023
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
46 |
0.023
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.023
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
41 |
0.023
|
|
|
|
memory
|
GO:0007613 |
94 |
0.023
|
|
|
|
protein maturation
|
GO:0051604 |
71 |
0.023
|
|
|
|
synapse organization
|
GO:0050808 |
196 |
0.022
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
36 |
0.022
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.022
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
27 |
0.022
|
|
|
|
tissue homeostasis
|
GO:0001894 |
36 |
0.022
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
109 |
0.022
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.022
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
29 |
0.022
|
Mouse |
|
|
secretion by cell
|
GO:0032940 |
101 |
0.022
|
|
|
|
eggshell formation
|
GO:0030703 |
105 |
0.021
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.021
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
18 |
0.021
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
2 |
0.021
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
4 |
0.021
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.021
|
Worm |
|
|
cellular chemical homeostasis
|
GO:0055082 |
40 |
0.021
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.021
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.021
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
17 |
0.021
|
|
|
|
spermatogenesis
|
GO:0007283 |
200 |
0.021
|
Rat Fly |
|
|
peptide hormone processing
|
GO:0016486 |
2 |
0.021
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.021
|
|
|
|
transmembrane transport
|
GO:0055085 |
139 |
0.021
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
50 |
0.021
|
|
|
|
axonogenesis
|
GO:0007409 |
290 |
0.020
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
128 |
0.020
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
23 |
0.020
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
42 |
0.020
|
|
|
|
regulation of mitosis
|
GO:0007088 |
56 |
0.020
|
|
|
|
heart process
|
GO:0003015 |
37 |
0.020
|
Zebrafish |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.020
|
Worm |
|
|
regulation of membrane potential
|
GO:0042391 |
35 |
0.020
|
|
|
|
nephron development
|
GO:0072006 |
3 |
0.020
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
14 |
0.020
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.020
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
72 |
0.020
|
Mouse |
|
|
regulation of transport
|
GO:0051049 |
181 |
0.019
|
|
|
|
response to sterol
|
GO:0036314 |
34 |
0.019
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
137 |
0.019
|
Worm |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
95 |
0.019
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
62 |
0.019
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
30 |
0.019
|
Human |
|
|
larval development
|
GO:0002164 |
104 |
0.019
|
Worm |
|
|
spindle organization
|
GO:0007051 |
253 |
0.019
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
179 |
0.019
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.018
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
109 |
0.018
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
110 |
0.018
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
17 |
0.018
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
105 |
0.018
|
|
|
|
response to monosaccharide
|
GO:0034284 |
4 |
0.018
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
65 |
0.018
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
28 |
0.018
|
|
|
|
protein secretion
|
GO:0009306 |
45 |
0.018
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
3 |
0.018
|
|
