Drosophila melanogaster

111 known processes

Vha55 (Dmel_CG17369)

Vacuolar H[+]-ATPase 55kD B subunit

(Aliases: CG17369,SzA,Dmel\CG17369,1208/13,vha55,l(3)j2E9,l(3)87Ca,VAT-2,l(3)SzA,V-ATPase)

Vha55 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ph reduction GO:0045851 7 0.579
ion transmembrane transport GO:0034220 122 0.546
ion transport GO:0006811 145 0.518
endomembrane system organization GO:0010256 119 0.491
negative regulation of biosynthetic process GO:0009890 277 0.449
proton transport GO:0015992 7 0.421
endosomal transport GO:0016197 44 0.386
intracellular ph reduction GO:0051452 7 0.360
establishment of localization in cell GO:0051649 402 0.330
regulation of catabolic process GO:0009894 170 0.322
phosphorylation GO:0016310 294 0.320
retina development in camera type eye GO:0060041 4 0.297
appendage development GO:0048736 401 0.295
growth GO:0040007 359 0.266
regulation of ph GO:0006885 7 0.244
small molecule metabolic process GO:0044281 305 0.236
wing disc morphogenesis GO:0007472 344 0.223
cation transport GO:0006812 110 0.220
regulation of intracellular signal transduction GO:1902531 236 0.210
molting cycle GO:0042303 56 0.197
intracellular transport GO:0046907 228 0.193
imaginal disc growth GO:0007446 37 0.186
tube development GO:0035295 244 0.179
imaginal disc derived wing morphogenesis GO:0007476 337 0.176
death GO:0016265 284 0.174
Worm
appendage morphogenesis GO:0035107 397 0.172
regulation of multicellular organismal development GO:2000026 414 0.162
negative regulation of transcription dna templated GO:0045892 237 0.162
regulation of transport GO:0051049 181 0.158
purine nucleoside triphosphate metabolic process GO:0009144 119 0.150
camera type eye development GO:0043010 4 0.149
organic substance transport GO:0071702 257 0.149
metal ion transport GO:0030001 74 0.138
inorganic cation transmembrane transport GO:0098662 61 0.132
catabolic process GO:0009056 409 0.131
imaginal disc derived appendage morphogenesis GO:0035114 395 0.121
oxoacid metabolic process GO:0043436 103 0.118
regulation of localization GO:0032879 275 0.117
embryo development ending in birth or egg hatching GO:0009792 152 0.117
Worm
single organism intracellular transport GO:1902582 207 0.108
tissue morphogenesis GO:0048729 297 0.108
regulation of cell differentiation GO:0045595 302 0.103
single organism cellular localization GO:1902580 180 0.102
mitotic spindle organization GO:0007052 220 0.102
response to abiotic stimulus GO:0009628 341 0.101
Worm
post embryonic appendage morphogenesis GO:0035120 385 0.101
transcription from rna polymerase ii promoter GO:0006366 368 0.099
purine nucleotide catabolic process GO:0006195 109 0.099
negative regulation of nucleic acid templated transcription GO:1903507 240 0.098
secretion GO:0046903 109 0.093
spindle organization GO:0007051 253 0.092
purine ribonucleoside metabolic process GO:0046128 127 0.089
organic substance catabolic process GO:1901575 308 0.088
regulation of protein metabolic process GO:0051246 256 0.088
nucleotide catabolic process GO:0009166 109 0.080
positive regulation of catabolic process GO:0009896 105 0.079
organ growth GO:0035265 56 0.075
nuclear import GO:0051170 51 0.075
purine ribonucleotide metabolic process GO:0009150 145 0.073
regulation of programmed cell death GO:0043067 152 0.071
Worm
vesicle mediated transport GO:0016192 381 0.069
rna localization GO:0006403 115 0.069
atp metabolic process GO:0046034 49 0.068
positive regulation of growth GO:0045927 75 0.068
endocytosis GO:0006897 310 0.068
endosome organization GO:0007032 9 0.068
macromolecule catabolic process GO:0009057 161 0.066
cation homeostasis GO:0055080 51 0.066
organonitrogen compound metabolic process GO:1901564 318 0.065
axis specification GO:0009798 167 0.064
purine ribonucleotide catabolic process GO:0009154 109 0.064
body morphogenesis GO:0010171 2 0.063
purine nucleotide metabolic process GO:0006163 146 0.063
establishment of tissue polarity GO:0007164 87 0.062
cellular metal ion homeostasis GO:0006875 31 0.062
Yeast
establishment of protein localization GO:0045184 163 0.061
response to organic substance GO:0010033 284 0.060
nucleoside phosphate catabolic process GO:1901292 110 0.059
imaginal disc derived appendage development GO:0048737 399 0.057
proteolysis GO:0006508 192 0.056
cation transmembrane transport GO:0098655 88 0.056
cell junction assembly GO:0034329 42 0.056
ribonucleoside monophosphate metabolic process GO:0009161 51 0.053
nucleoside metabolic process GO:0009116 127 0.053
negative regulation of gene expression GO:0010629 387 0.052
cellular ion homeostasis GO:0006873 39 0.052
kidney development GO:0001822 3 0.051
nucleoside triphosphate catabolic process GO:0009143 108 0.049
neurological system process GO:0050877 358 0.049
purine nucleoside triphosphate catabolic process GO:0009146 108 0.048
lipid modification GO:0030258 24 0.048
purine ribonucleoside catabolic process GO:0046130 112 0.048
eye development GO:0001654 323 0.047
response to oxygen containing compound GO:1901700 200 0.047
epithelial cell differentiation GO:0030855 322 0.047
response to unfolded protein GO:0006986 9 0.046
single organism membrane organization GO:0044802 93 0.046
regulation of protein localization GO:0032880 76 0.044
cellular response to chemical stimulus GO:0070887 199 0.044
regulation of hydrolase activity GO:0051336 97 0.044
inorganic ion transmembrane transport GO:0098660 73 0.044
single organism catabolic process GO:0044712 228 0.043
developmental growth GO:0048589 280 0.043
actin cytoskeleton organization GO:0030036 206 0.043
developmental maturation GO:0021700 172 0.043
glycosyl compound catabolic process GO:1901658 112 0.043
cellular catabolic process GO:0044248 372 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.043
nucleobase containing compound catabolic process GO:0034655 165 0.043
nucleoside triphosphate metabolic process GO:0009141 120 0.043
secretion by cell GO:0032940 101 0.043
negative regulation of cell cycle GO:0045786 116 0.042
regulation of growth GO:0040008 233 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.042
negative regulation of developmental process GO:0051093 201 0.041
protein modification process GO:0036211 438 0.040
cellular protein modification process GO:0006464 438 0.040
positive regulation of response to stimulus GO:0048584 323 0.040
purine nucleoside metabolic process GO:0042278 127 0.039
glycosyl compound metabolic process GO:1901657 127 0.039
sensory perception of sound GO:0007605 56 0.039
gastrulation GO:0007369 70 0.038
ribonucleotide metabolic process GO:0009259 145 0.038
cell cell junction organization GO:0045216 55 0.038
positive regulation of multicellular organismal process GO:0051240 143 0.038
ribonucleoside triphosphate metabolic process GO:0009199 119 0.037
nucleoside catabolic process GO:0009164 112 0.037
negative regulation of cellular metabolic process GO:0031324 382 0.036
ribonucleoside metabolic process GO:0009119 127 0.036
multicellular organismal aging GO:0010259 140 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
negative regulation of epithelial cell proliferation GO:0050680 4 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
protein localization GO:0008104 284 0.033
eye morphogenesis GO:0048592 260 0.032
transmembrane transport GO:0055085 139 0.032
morphogenesis of an epithelium GO:0002009 276 0.032
ribonucleotide catabolic process GO:0009261 109 0.032
cellular divalent inorganic cation homeostasis GO:0072503 23 0.032
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.032
g2 dna damage checkpoint GO:0031572 69 0.032
regulation of protein transport GO:0051223 57 0.031
apical junction assembly GO:0043297 32 0.031
negative regulation of cellular biosynthetic process GO:0031327 277 0.031
regulation of molecular function GO:0065009 217 0.031
protein targeting to nucleus GO:0044744 51 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.030
embryonic morphogenesis GO:0048598 206 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
ribonucleoside triphosphate catabolic process GO:0009203 108 0.030
regulation of hormone levels GO:0010817 40 0.029
cell death GO:0008219 279 0.029
Worm
lipid biosynthetic process GO:0008610 46 0.029
basement membrane organization GO:0071711 10 0.029
metal ion homeostasis GO:0055065 44 0.028
Yeast
ribose phosphate metabolic process GO:0019693 145 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.028
cellular macromolecule localization GO:0070727 220 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
heterocycle catabolic process GO:0046700 166 0.027
autophagy GO:0006914 108 0.026
positive regulation of signaling GO:0023056 243 0.026
membrane organization GO:0061024 112 0.025
regulation of cell cycle process GO:0010564 181 0.025
tube morphogenesis GO:0035239 191 0.025
positive regulation of programmed cell death GO:0043068 62 0.024
Worm
response to wounding GO:0009611 94 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
regulation of hemocyte proliferation GO:0035206 37 0.023
regulation of wnt signaling pathway GO:0030111 68 0.023
regulation of notch signaling pathway GO:0008593 100 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
muscle organ development GO:0007517 127 0.023
epidermis development GO:0008544 65 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.022
nucleocytoplasmic transport GO:0006913 72 0.022
protein import into nucleus GO:0006606 51 0.021
regulation of catalytic activity GO:0050790 185 0.021
vacuolar acidification GO:0007035 4 0.021
golgi organization GO:0007030 66 0.021
mitochondrion organization GO:0007005 65 0.021
extracellular matrix organization GO:0030198 32 0.021
compound eye morphogenesis GO:0001745 249 0.020
pigmentation GO:0043473 75 0.020
cell proliferation GO:0008283 299 0.020
regulation of phosphorylation GO:0042325 147 0.020
organic acid metabolic process GO:0006082 103 0.020
peptide metabolic process GO:0006518 80 0.020
notch signaling pathway GO:0007219 120 0.020
positive regulation of signal transduction GO:0009967 223 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
Worm
cellular monovalent inorganic cation homeostasis GO:0030004 7 0.020
organophosphate catabolic process GO:0046434 112 0.020
aging GO:0007568 143 0.019
cellular response to decreased oxygen levels GO:0036294 30 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.019
mitotic g2 dna damage checkpoint GO:0007095 69 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of protein modification process GO:0031399 112 0.019
regulation of nucleoside metabolic process GO:0009118 50 0.019
protein transport GO:0015031 155 0.018
anterior posterior pattern specification GO:0009952 136 0.018
establishment of planar polarity GO:0001736 87 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
neuroblast proliferation GO:0007405 74 0.018
cellular homeostasis GO:0019725 80 0.018
modification dependent macromolecule catabolic process GO:0043632 79 0.018
ion homeostasis GO:0050801 55 0.017
establishment of rna localization GO:0051236 47 0.017
molting cycle chitin based cuticle GO:0007591 56 0.017
programmed cell death GO:0012501 257 0.017
Worm
urogenital system development GO:0001655 72 0.017
lipid localization GO:0010876 54 0.017
central nervous system development GO:0007417 201 0.017
cellular cation homeostasis GO:0030003 38 0.017
cell junction organization GO:0034330 57 0.017
hydrogen ion transmembrane transport GO:1902600 5 0.017
mapk cascade GO:0000165 107 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
regulation of phosphatase activity GO:0010921 3 0.016
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.016
regulation of secretion by cell GO:1903530 39 0.016
purine containing compound catabolic process GO:0072523 112 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
striated muscle myosin thick filament assembly GO:0071688 3 0.016
gastrulation with mouth forming first GO:0001703 36 0.016
olfactory behavior GO:0042048 97 0.016
smoothened signaling pathway GO:0007224 49 0.016
regulation of cellular localization GO:0060341 136 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
cellular chemical homeostasis GO:0055082 40 0.016
cellular macromolecule catabolic process GO:0044265 136 0.015
sterol homeostasis GO:0055092 4 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
larval development GO:0002164 104 0.015
Worm
monovalent inorganic cation transport GO:0015672 40 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
response to topologically incorrect protein GO:0035966 10 0.015
blastoderm segmentation GO:0007350 159 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.015
digestive system development GO:0055123 149 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
cholesterol homeostasis GO:0042632 3 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
apoptotic process GO:0006915 159 0.014
Worm
regulation of establishment of protein localization GO:0070201 61 0.014
purine containing compound metabolic process GO:0072521 155 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
protein catabolic process GO:0030163 101 0.014
regulation of cell proliferation GO:0042127 163 0.014
cytoplasmic transport GO:0016482 130 0.014
lateral inhibition GO:0046331 206 0.013
chemical homeostasis GO:0048878 92 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
determination of left right symmetry GO:0007368 9 0.013
organophosphate metabolic process GO:0019637 195 0.013
positive regulation of gtp catabolic process GO:0033126 43 0.013
maintenance of location GO:0051235 73 0.013
positive regulation of developmental process GO:0051094 143 0.013
embryonic hindgut morphogenesis GO:0048619 48 0.013
negative regulation of growth GO:0045926 84 0.013
segmentation GO:0035282 207 0.013
regulation of apoptotic process GO:0042981 130 0.013
regulation of steroid metabolic process GO:0019218 2 0.012
glial cell development GO:0021782 27 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
developmental pigmentation GO:0048066 68 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
energy derivation by oxidation of organic compounds GO:0015980 32 0.012
single organism biosynthetic process GO:0044711 206 0.012
organelle assembly GO:0070925 198 0.012
protein complex biogenesis GO:0070271 201 0.012
Yeast
negative regulation of cell cycle process GO:0010948 109 0.012
pigment granule organization GO:0048753 12 0.012
homeostatic process GO:0042592 199 0.012
morphogenesis of a branching structure GO:0001763 45 0.012
protein maturation GO:0051604 71 0.012
cognition GO:0050890 141 0.012
embryonic axis specification GO:0000578 107 0.012
acyl coa metabolic process GO:0006637 3 0.012
myosin filament organization GO:0031033 5 0.012
cellular protein localization GO:0034613 160 0.012
protein ubiquitination GO:0016567 70 0.012
negative regulation of nervous system development GO:0051961 92 0.012
xenobiotic transport GO:0042908 1 0.011
monocarboxylic acid metabolic process GO:0032787 29 0.011
cellular response to organic substance GO:0071310 132 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
gliogenesis GO:0042063 80 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
regulation of secretion GO:0051046 44 0.011
mitotic nuclear division GO:0007067 213 0.011
response to oxygen levels GO:0070482 59 0.011
Worm
actin filament based process GO:0030029 220 0.011
sulfur compound metabolic process GO:0006790 59 0.011
positive regulation of cell communication GO:0010647 250 0.011
stem cell differentiation GO:0048863 117 0.011
response to organic cyclic compound GO:0014070 89 0.011
long term memory GO:0007616 62 0.011
anterior posterior axis specification GO:0009948 109 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.010
aromatic compound catabolic process GO:0019439 166 0.010
response to hypoxia GO:0001666 53 0.010
Worm
developmental growth involved in morphogenesis GO:0060560 65 0.010
regulation of cell death GO:0010941 173 0.010
Worm
cellular ketone metabolic process GO:0042180 24 0.010
regulation of protein import into nucleus GO:0042306 28 0.010
muscle attachment GO:0016203 36 0.010
cellular response to ethanol GO:0071361 4 0.010
substrate adhesion dependent cell spreading GO:0034446 2 0.010
positive regulation of gtpase activity GO:0043547 43 0.010
positive regulation of cell motility GO:2000147 3 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
hindbrain development GO:0030902 2 0.010

Vha55 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.145
disease of cellular proliferation DOID:14566 0 0.048
cancer DOID:162 0 0.041
organ system cancer DOID:0050686 0 0.041
nervous system disease DOID:863 0 0.037
renal tubular transport disease DOID:447 0 0.022
kidney disease DOID:557 0 0.022
urinary system disease DOID:18 0 0.022