Drosophila melanogaster

214 known processes

mbc (Dmel_CG10379)

myoblast city

(Aliases: DOCK180,dock180,Dock180,Dmel\CG10379,CG10379,MBC/DOCK180,MBC,Mbc,Dm MBC,Su(rac)1)

mbc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell migration GO:0016477 238 1.000
localization of cell GO:0051674 257 1.000
border follicle cell migration GO:0007298 113 1.000
cell motility GO:0048870 251 1.000
ovarian follicle cell migration GO:0007297 121 1.000
syncytium formation by plasma membrane fusion GO:0000768 43 1.000
epithelial cell migration GO:0010631 148 1.000
syncytium formation GO:0006949 43 1.000
epithelium migration GO:0090132 148 1.000
tissue migration GO:0090130 155 1.000
muscle cell differentiation GO:0042692 103 1.000
ameboidal type cell migration GO:0001667 151 0.999
myoblast fusion GO:0007520 43 0.999
striated muscle cell differentiation GO:0051146 90 0.999
cell projection assembly GO:0030031 94 0.998
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.997
ovarian follicle cell development GO:0030707 248 0.997
actin filament based process GO:0030029 220 0.996
regulation of cellular component biogenesis GO:0044087 201 0.994
regulation of rho protein signal transduction GO:0035023 20 0.994
muscle structure development GO:0061061 224 0.992
actin cytoskeleton organization GO:0030036 206 0.991
embryonic morphogenesis GO:0048598 206 0.984
columnar cuboidal epithelial cell development GO:0002066 249 0.984
skeletal muscle organ development GO:0060538 48 0.979
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.975
axonogenesis GO:0007409 290 0.974
chemotaxis GO:0006935 249 0.969
Mouse
epithelial cell development GO:0002064 274 0.967
regulation of multicellular organismal development GO:2000026 414 0.966
regulation of locomotion GO:0040012 42 0.957
developmental growth GO:0048589 280 0.957
positive regulation of phosphate metabolic process GO:0045937 139 0.955
myotube differentiation GO:0014902 46 0.954
neuron projection guidance GO:0097485 241 0.954
regulation of organelle organization GO:0033043 196 0.950
regulation of phosphate metabolic process GO:0019220 210 0.948
enzyme linked receptor protein signaling pathway GO:0007167 179 0.940
positive regulation of gtpase activity GO:0043547 43 0.939
filopodium assembly GO:0046847 33 0.938
regulation of cell migration GO:0030334 22 0.937
digestive system development GO:0055123 149 0.933
digestive tract development GO:0048565 149 0.928
protein complex assembly GO:0006461 200 0.924
rho protein signal transduction GO:0007266 14 0.921
protein complex biogenesis GO:0070271 201 0.918
epithelial cell differentiation GO:0030855 322 0.903
positive regulation of rac gtpase activity GO:0032855 8 0.902
regulation of immune system process GO:0002682 176 0.895
actin filament bundle organization GO:0061572 28 0.894
positive regulation of cell communication GO:0010647 250 0.886
actin filament organization GO:0007015 126 0.885
positive regulation of immune system process GO:0002684 68 0.883
central nervous system development GO:0007417 201 0.882
muscle attachment GO:0016203 36 0.880
catabolic process GO:0009056 409 0.876
regulation of filopodium assembly GO:0051489 24 0.868
positive regulation of cellular component biogenesis GO:0044089 80 0.867
kidney epithelium development GO:0072073 3 0.863
regulation of epithelial cell migration GO:0010632 12 0.861
positive regulation of actin filament polymerization GO:0030838 11 0.859
ribonucleotide metabolic process GO:0009259 145 0.857
regulation of localization GO:0032879 275 0.853
Mouse
regulation of cell motility GO:2000145 23 0.847
actin cytoskeleton reorganization GO:0031532 22 0.843
regulation of cell projection assembly GO:0060491 30 0.841
respiratory system development GO:0060541 213 0.839
hindgut morphogenesis GO:0007442 58 0.839
small molecule metabolic process GO:0044281 305 0.825
positive regulation of cellular component organization GO:0051130 156 0.823
Mouse
secretion GO:0046903 109 0.818
synaptic growth at neuromuscular junction GO:0051124 119 0.816
actin filament polymerization GO:0030041 27 0.812
regulation of actin filament polymerization GO:0030833 25 0.810
vesicle mediated transport GO:0016192 381 0.807
Mouse Worm
regulation of cell shape GO:0008360 113 0.806
actomyosin structure organization GO:0031032 56 0.805
tube development GO:0035295 244 0.803
sensory perception of mechanical stimulus GO:0050954 72 0.801
regulation of intracellular signal transduction GO:1902531 236 0.797
glycosyl compound catabolic process GO:1901658 112 0.795
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.792
activation of ras gtpase activity GO:0032856 6 0.791
embryo development ending in birth or egg hatching GO:0009792 152 0.790
positive regulation of cell motility GO:2000147 3 0.787
regulation of cellular component movement GO:0051270 42 0.781
axon development GO:0061564 297 0.779
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.779
positive regulation of rho gtpase activity GO:0032321 19 0.777
muscle organ development GO:0007517 127 0.777
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.776
peptidyl tyrosine phosphorylation GO:0018108 24 0.775
organophosphate metabolic process GO:0019637 195 0.771
body morphogenesis GO:0010171 2 0.757
regulation of cell morphogenesis GO:0022604 163 0.756
intracellular signal transduction GO:0035556 300 0.741
hindgut development GO:0061525 58 0.739
endocytosis GO:0006897 310 0.739
Mouse Worm
spermatid differentiation GO:0048515 114 0.738
regulation of phosphorus metabolic process GO:0051174 210 0.737
cellular amino acid metabolic process GO:0006520 61 0.734
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.731
urogenital system development GO:0001655 72 0.727
transcription from rna polymerase ii promoter GO:0006366 368 0.725
positive regulation of cell migration GO:0030335 2 0.724
renal system development GO:0072001 72 0.724
ion transmembrane transport GO:0034220 122 0.722
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.721
regulation of cellular amino acid metabolic process GO:0006521 0 0.716
purine nucleoside triphosphate metabolic process GO:0009144 119 0.716
reproductive structure development GO:0048608 74 0.708
positive regulation of cell differentiation GO:0045597 64 0.707
regulation of growth GO:0040008 233 0.706
defense response GO:0006952 300 0.706
regulation of response to stress GO:0080134 200 0.705
regulation of actin cytoskeleton organization GO:0032956 42 0.704
immune effector process GO:0002252 98 0.701
Mouse
cortical actin cytoskeleton organization GO:0030866 24 0.698
positive regulation of phosphorus metabolic process GO:0010562 139 0.682
cell proliferation GO:0008283 299 0.681
Mouse
secretion by cell GO:0032940 101 0.681
phosphorylation GO:0016310 294 0.671
axon guidance GO:0007411 233 0.669
positive regulation of phagocytosis engulfment GO:0060100 1 0.658
guanosine containing compound catabolic process GO:1901069 74 0.657
nucleobase containing small molecule metabolic process GO:0055086 174 0.655
camera type eye development GO:0043010 4 0.653
regulation of rho gtpase activity GO:0032319 20 0.645
regulation of anatomical structure morphogenesis GO:0022603 242 0.640
response to wounding GO:0009611 94 0.638
purine nucleoside metabolic process GO:0042278 127 0.636
cellular amine metabolic process GO:0044106 12 0.632
regulation of epithelial cell differentiation GO:0030856 4 0.631
apoptotic cell clearance GO:0043277 14 0.622
Worm
cellular protein complex assembly GO:0043623 71 0.621
positive regulation of hydrolase activity GO:0051345 78 0.620
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.619
kidney development GO:0001822 3 0.614
regulation of actin filament length GO:0030832 27 0.610
peptidyl tyrosine modification GO:0018212 24 0.602
amine metabolic process GO:0009308 12 0.599
regulation of actin polymerization or depolymerization GO:0008064 27 0.597
cellular macromolecular complex assembly GO:0034622 153 0.591
guanosine containing compound metabolic process GO:1901068 74 0.583
purine ribonucleotide catabolic process GO:0009154 109 0.581
regulation of cell projection organization GO:0031344 92 0.581
purine nucleotide catabolic process GO:0006195 109 0.581
regulation of protein polymerization GO:0032271 28 0.574
negative regulation of response to stimulus GO:0048585 258 0.571
muscle cell development GO:0055001 50 0.568
immune system process GO:0002376 347 0.567
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.563
purine nucleoside catabolic process GO:0006152 112 0.562
ribonucleoside catabolic process GO:0042454 112 0.562
carbohydrate derivative metabolic process GO:1901135 217 0.556
actin polymerization or depolymerization GO:0008154 31 0.549
tissue morphogenesis GO:0048729 297 0.548
gtp catabolic process GO:0006184 72 0.540
organic acid metabolic process GO:0006082 103 0.535
glial cell migration GO:0008347 31 0.535
positive regulation of lipid metabolic process GO:0045834 4 0.531
cellular response to chemical stimulus GO:0070887 199 0.531
cellular ketone metabolic process GO:0042180 24 0.527
positive regulation of ras gtpase activity GO:0032320 36 0.525
response to growth factor GO:0070848 31 0.524
single organismal cell cell adhesion GO:0016337 45 0.524
ras protein signal transduction GO:0007265 88 0.523
nucleoside triphosphate metabolic process GO:0009141 120 0.518
sex differentiation GO:0007548 81 0.516
lamellipodium assembly GO:0030032 21 0.515
positive regulation of nucleotide metabolic process GO:0045981 55 0.514
rac protein signal transduction GO:0016601 3 0.512
positive regulation of nucleic acid templated transcription GO:1903508 266 0.507
regulation of lamellipodium assembly GO:0010591 15 0.507
morphogenesis of embryonic epithelium GO:0016331 94 0.504
positive regulation of cytoskeleton organization GO:0051495 21 0.502
carboxylic acid metabolic process GO:0019752 92 0.502
establishment of localization in cell GO:0051649 402 0.494
response to biotic stimulus GO:0009607 294 0.492
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.490
endomembrane system organization GO:0010256 119 0.487
nuclear division GO:0000280 332 0.486
regulation of cellular amine metabolic process GO:0033238 3 0.483
negative regulation of cell communication GO:0010648 223 0.481
regulation of cellular component size GO:0032535 98 0.477
regulation of endocytosis GO:0030100 37 0.476
Mouse
purine ribonucleoside metabolic process GO:0046128 127 0.474
positive regulation of response to stimulus GO:0048584 323 0.468
wound healing GO:0042060 75 0.467
positive regulation of catalytic activity GO:0043085 118 0.465
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.465
regulation of immune response GO:0050776 118 0.462
regulation of molecular function GO:0065009 217 0.460
positive regulation of multicellular organismal process GO:0051240 143 0.460
actin filament bundle assembly GO:0051017 26 0.459
purine nucleotide metabolic process GO:0006163 146 0.445
regionalization GO:0003002 416 0.444
regulation of secretion GO:0051046 44 0.441
negative regulation of growth GO:0045926 84 0.435
negative regulation of cellular metabolic process GO:0031324 382 0.435
regulation of protein complex assembly GO:0043254 42 0.429
malpighian tubule development GO:0072002 64 0.425
tube morphogenesis GO:0035239 191 0.420
positive regulation of phosphorylation GO:0042327 87 0.413
positive regulation of developmental process GO:0051094 143 0.410
regulation of actin filament based process GO:0032970 42 0.409
regulation of cellular ketone metabolic process GO:0010565 3 0.408
signal transduction by phosphorylation GO:0023014 107 0.402
ribonucleoside triphosphate catabolic process GO:0009203 108 0.402
positive regulation of organelle organization GO:0010638 65 0.395
regulation of cell proliferation GO:0042127 163 0.392
growth GO:0040007 359 0.379
organelle fission GO:0048285 340 0.375
organonitrogen compound metabolic process GO:1901564 318 0.374
hematopoietic or lymphoid organ development GO:0048534 57 0.373
Mouse
leg disc morphogenesis GO:0007478 80 0.370
nucleotide metabolic process GO:0009117 161 0.367
activation of rac gtpase activity GO:0032863 3 0.367
single organism catabolic process GO:0044712 228 0.367
positive regulation of signaling GO:0023056 243 0.364
positive regulation of protein polymerization GO:0032273 14 0.364
maintenance of location GO:0051235 73 0.360
digestive tract morphogenesis GO:0048546 127 0.358
neuromuscular junction development GO:0007528 149 0.355
positive regulation of intracellular signal transduction GO:1902533 116 0.354
regulation of transport GO:0051049 181 0.349
Mouse
negative regulation of rho protein signal transduction GO:0035024 1 0.347
transmembrane transport GO:0055085 139 0.346
gtp metabolic process GO:0046039 72 0.345
carbohydrate derivative catabolic process GO:1901136 118 0.343
reproductive system development GO:0061458 74 0.342
purine nucleoside triphosphate catabolic process GO:0009146 108 0.338
nucleotide catabolic process GO:0009166 109 0.338
positive regulation of gene expression GO:0010628 290 0.332
mapk cascade GO:0000165 107 0.329
ribonucleoside metabolic process GO:0009119 127 0.321
cellular response to growth factor stimulus GO:0071363 30 0.320
embryonic hindgut morphogenesis GO:0048619 48 0.319
nucleoside phosphate catabolic process GO:1901292 110 0.315
regulation of transmembrane transport GO:0034762 27 0.308
appendage morphogenesis GO:0035107 397 0.306
immune system development GO:0002520 57 0.306
Mouse
positive regulation of protein kinase activity GO:0045860 25 0.302
neuron migration GO:0001764 5 0.301
negative regulation of signal transduction GO:0009968 206 0.300
oxoacid metabolic process GO:0043436 103 0.296
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.283
regulation of cell death GO:0010941 173 0.282
positive regulation of transport GO:0051050 92 0.281
Mouse
mesoderm development GO:0007498 78 0.281
gland development GO:0048732 191 0.281
response to endogenous stimulus GO:0009719 119 0.279
regulation of axon extension GO:0030516 8 0.278
regulation of phosphorylation GO:0042325 147 0.278
cellular component assembly involved in morphogenesis GO:0010927 151 0.276
regulation of nucleotide catabolic process GO:0030811 48 0.276
nucleoside metabolic process GO:0009116 127 0.276
positive regulation of gtp catabolic process GO:0033126 43 0.272
ribonucleoside triphosphate metabolic process GO:0009199 119 0.270
telencephalon development GO:0021537 2 0.266
ribose phosphate metabolic process GO:0019693 145 0.264
regulation of cellular response to growth factor stimulus GO:0090287 13 0.263
innate immune response GO:0045087 144 0.262
peripheral nervous system development GO:0007422 52 0.260
positive regulation of cell adhesion GO:0045785 10 0.260
positive regulation of cellular amine metabolic process GO:0033240 0 0.259
skin development GO:0043588 65 0.257
nephron tubule development GO:0072080 3 0.256
epithelial tube morphogenesis GO:0060562 88 0.253
positive regulation of rna biosynthetic process GO:1902680 266 0.249
regulation of protein modification process GO:0031399 112 0.247
positive regulation of signal transduction GO:0009967 223 0.245
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.243
imaginal disc derived wing morphogenesis GO:0007476 337 0.242
purine containing compound catabolic process GO:0072523 112 0.240
positive regulation of protein metabolic process GO:0051247 128 0.239
neuron recognition GO:0008038 101 0.238
purine ribonucleotide metabolic process GO:0009150 145 0.237
regulation of response to external stimulus GO:0032101 115 0.232
regulation of nucleotide metabolic process GO:0006140 62 0.231
positive regulation of protein complex assembly GO:0031334 22 0.230
morphogenesis of an epithelium GO:0002009 276 0.228
head development GO:0060322 135 0.225
appendage development GO:0048736 401 0.225
positive regulation of molecular function GO:0044093 136 0.223
purine containing compound metabolic process GO:0072521 155 0.222
dorsal ventral axon guidance GO:0033563 2 0.222
positive regulation of growth GO:0045927 75 0.221
development of primary sexual characteristics GO:0045137 50 0.221
positive regulation of protein modification process GO:0031401 58 0.220
erk1 and erk2 cascade GO:0070371 39 0.219
immune response GO:0006955 246 0.219
Mouse
blastoderm segmentation GO:0007350 159 0.217
aromatic compound catabolic process GO:0019439 166 0.216
regulation of small gtpase mediated signal transduction GO:0051056 93 0.216
sensory perception GO:0007600 196 0.215
regulation of cytoskeleton organization GO:0051493 89 0.215
regulation of mapk cascade GO:0043408 92 0.214
response to abiotic stimulus GO:0009628 341 0.213
membrane organization GO:0061024 112 0.212
Mouse Worm
meiotic cell cycle GO:0051321 171 0.211
regulation of secretion by cell GO:1903530 39 0.207
response to decreased oxygen levels GO:0036293 58 0.207
regulation of gtpase activity GO:0043087 44 0.206
regulation of synapse organization GO:0050807 110 0.205
regulation of cell division GO:0051302 72 0.202
response to external biotic stimulus GO:0043207 293 0.201
regulation of axonogenesis GO:0050770 32 0.200
cellular protein modification process GO:0006464 438 0.199
regulation of epithelial cell proliferation GO:0050678 4 0.199
negative regulation of biosynthetic process GO:0009890 277 0.198
muscle tissue development GO:0060537 30 0.197
post embryonic appendage morphogenesis GO:0035120 385 0.197
embryonic hemopoiesis GO:0035162 26 0.194
dorsal ventral pattern formation GO:0009953 133 0.194
regulation of cellular localization GO:0060341 136 0.194
regulation of apoptotic process GO:0042981 130 0.193
muscle fiber development GO:0048747 12 0.188
regulation of synapse assembly GO:0051963 94 0.187
glycosyl compound metabolic process GO:1901657 127 0.186
substrate dependent cell migration GO:0006929 3 0.185
regulation of system process GO:0044057 36 0.185
cilium morphogenesis GO:0060271 39 0.184
eye development GO:0001654 323 0.183
positive regulation of nucleoside metabolic process GO:0045979 47 0.181
regulation of ras gtpase activity GO:0032318 38 0.181
multi multicellular organism process GO:0044706 123 0.180
larval development GO:0002164 104 0.179
organelle localization GO:0051640 148 0.177
stress fiber assembly GO:0043149 6 0.176
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.175
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.175
regulation of erbb signaling pathway GO:1901184 42 0.174
negative regulation of rna biosynthetic process GO:1902679 240 0.174
purine ribonucleoside catabolic process GO:0046130 112 0.173
regulation of ras protein signal transduction GO:0046578 93 0.171
positive regulation of biosynthetic process GO:0009891 316 0.171
forebrain development GO:0030900 2 0.171
regulation of mitotic cell cycle GO:0007346 190 0.170
regulation of anatomical structure size GO:0090066 163 0.170
salivary gland development GO:0007431 162 0.167
regulation of defense response GO:0031347 102 0.167
positive regulation of developmental growth GO:0048639 62 0.166
regulation of protein metabolic process GO:0051246 256 0.166
nucleoside triphosphate catabolic process GO:0009143 108 0.164
leg disc development GO:0035218 92 0.164
malpighian tubule morphogenesis GO:0007443 44 0.164
positive regulation of cellular biosynthetic process GO:0031328 316 0.164
regulation of cellular protein metabolic process GO:0032268 243 0.158
small gtpase mediated signal transduction GO:0007264 88 0.158
regulation of response to wounding GO:1903034 19 0.158
embryonic organ development GO:0048568 50 0.157
multi organism behavior GO:0051705 175 0.156
regulation of cell cycle GO:0051726 291 0.156
developmental maturation GO:0021700 172 0.155
anterior posterior axis specification embryo GO:0008595 103 0.154
jak stat cascade GO:0007259 49 0.153
cell recognition GO:0008037 102 0.153
Mouse
cellular catabolic process GO:0044248 372 0.153
adult behavior GO:0030534 137 0.151
striated muscle cell development GO:0055002 50 0.149
kidney morphogenesis GO:0060993 3 0.149
stem cell proliferation GO:0072089 88 0.148
cellular response to organic substance GO:0071310 132 0.147
chemical homeostasis GO:0048878 92 0.147
imaginal disc derived appendage development GO:0048737 399 0.146
lipid metabolic process GO:0006629 121 0.145
negative regulation of phosphorylation GO:0042326 35 0.145
synapse assembly GO:0007416 143 0.144
nephron development GO:0072006 3 0.142
homeostatic process GO:0042592 199 0.141
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.140
positive regulation of secretion by cell GO:1903532 20 0.140
cortical cytoskeleton organization GO:0030865 29 0.140
regulation of purine nucleotide catabolic process GO:0033121 48 0.139
positive regulation of immune response GO:0050778 63 0.138
heterocycle catabolic process GO:0046700 166 0.134
pericardial nephrocyte differentiation GO:0061320 9 0.131
positive regulation of catabolic process GO:0009896 105 0.130
regulation of embryonic development GO:0045995 68 0.129
cation transport GO:0006812 110 0.129
gonad development GO:0008406 50 0.128
nucleobase containing compound catabolic process GO:0034655 165 0.128
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.127
adherens junction organization GO:0034332 27 0.127
regulation of neurogenesis GO:0050767 158 0.126
regulation of ion transport GO:0043269 39 0.126
negative regulation of gene expression GO:0010629 387 0.125
extracellular structure organization GO:0043062 46 0.125
biological adhesion GO:0022610 138 0.123
regulation of kinase activity GO:0043549 53 0.123
striated muscle tissue development GO:0014706 27 0.122
phagocytosis GO:0006909 215 0.121
Mouse Worm
cell type specific apoptotic process GO:0097285 38 0.121
protein localization GO:0008104 284 0.120
somatic stem cell maintenance GO:0035019 14 0.119
axis specification GO:0009798 167 0.119
response to organic substance GO:0010033 284 0.119
regulation of purine nucleotide metabolic process GO:1900542 62 0.119
developmental growth involved in morphogenesis GO:0060560 65 0.118
muscle system process GO:0003012 21 0.118
unidimensional cell growth GO:0009826 15 0.117
cell division GO:0051301 248 0.116
response to peptide hormone GO:0043434 29 0.116
macromolecular complex assembly GO:0065003 256 0.115
hemopoiesis GO:0030097 46 0.115
Mouse
negative regulation of cell death GO:0060548 81 0.114
neuron death GO:0070997 27 0.114
negative regulation of programmed cell death GO:0043069 72 0.114
regulation of developmental growth GO:0048638 174 0.114
cellular response to endogenous stimulus GO:0071495 80 0.111
negative regulation of epithelial cell proliferation GO:0050680 4 0.111
positive regulation of transcription dna templated GO:0045893 266 0.109
establishment of organelle localization GO:0051656 122 0.106
multi organism reproductive behavior GO:0044705 121 0.105
protein modification process GO:0036211 438 0.105
single organism cell adhesion GO:0098602 47 0.104
engulfment of apoptotic cell GO:0043652 6 0.102
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.102
cellular lipid metabolic process GO:0044255 83 0.101
regulation of nervous system development GO:0051960 248 0.098
erbb signaling pathway GO:0038127 58 0.097
regulation of nucleoside metabolic process GO:0009118 50 0.097
inositol lipid mediated signaling GO:0048017 4 0.097
nephron tubule morphogenesis GO:0072078 3 0.096
positive regulation of endocytosis GO:0045807 22 0.096
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.096
muscle tissue morphogenesis GO:0060415 2 0.095
protein phosphorylation GO:0006468 169 0.095
endoderm formation GO:0001706 3 0.095
negative regulation of nucleic acid templated transcription GO:1903507 240 0.094
neurological system process GO:0050877 358 0.093
neuroblast proliferation GO:0007405 74 0.093
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.093
regulation of programmed cell death GO:0043067 152 0.092
protein polymerization GO:0051258 42 0.092
single organism behavior GO:0044708 391 0.092
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.092
phosphatidylinositol mediated signaling GO:0048015 4 0.090
multicellular organismal reproductive behavior GO:0033057 110 0.090
regulation of cell adhesion GO:0030155 27 0.090
male gamete generation GO:0048232 201 0.090
cognition GO:0050890 141 0.089
negative regulation of developmental process GO:0051093 201 0.089
positive regulation of nervous system development GO:0051962 69 0.089
proteolysis GO:0006508 192 0.088
positive regulation of cell proliferation GO:0008284 47 0.088
gastrulation GO:0007369 70 0.087
heart development GO:0007507 82 0.087
stress activated protein kinase signaling cascade GO:0031098 55 0.086
nucleoside catabolic process GO:0009164 112 0.086
multicellular organismal homeostasis GO:0048871 41 0.084
renal tubule morphogenesis GO:0061333 44 0.084
cellular nitrogen compound catabolic process GO:0044270 165 0.084
cell migration involved in gastrulation GO:0042074 9 0.084
positive regulation of rna metabolic process GO:0051254 271 0.083
organophosphate catabolic process GO:0046434 112 0.083
response to insulin GO:0032868 29 0.082
meiotic nuclear division GO:0007126 151 0.082
positive regulation of filopodium assembly GO:0051491 15 0.082
wnt signaling pathway GO:0016055 98 0.081
neuroblast division GO:0055057 35 0.080
receptor mediated endocytosis GO:0006898 21 0.080
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.079
positive regulation of phagocytosis GO:0050766 3 0.079
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.079
negative regulation of cellular protein metabolic process GO:0032269 85 0.078
regulation of transferase activity GO:0051338 58 0.078
ion transport GO:0006811 145 0.077
bmp signaling pathway GO:0030509 27 0.077
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.076
motor neuron axon guidance GO:0008045 58 0.075
nephrocyte differentiation GO:0061319 12 0.074
somatic muscle development GO:0007525 66 0.074
organic substance catabolic process GO:1901575 308 0.074
nucleoside phosphate metabolic process GO:0006753 162 0.074
stress activated mapk cascade GO:0051403 52 0.073
protein catabolic process GO:0030163 101 0.072
myofibril assembly GO:0030239 36 0.072
glial cell differentiation GO:0010001 35 0.071
regulation of actin filament bundle assembly GO:0032231 8 0.070
hindbrain development GO:0030902 2 0.070
cell growth GO:0016049 108 0.068
regulation of neuron differentiation GO:0045664 103 0.068
cation transmembrane transport GO:0098655 88 0.068
response to organonitrogen compound GO:0010243 75 0.067
cell activation GO:0001775 9 0.067
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.067
spermatid development GO:0007286 98 0.066
reproductive behavior GO:0019098 122 0.066
single organism cellular localization GO:1902580 180 0.066
Mouse
positive regulation of nucleotide catabolic process GO:0030813 46 0.066
negative regulation of synapse assembly GO:0051964 39 0.065
metal ion transport GO:0030001 74 0.064
locomotory behavior GO:0007626 176 0.064

mbc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.624
disease of cellular proliferation DOID:14566 0 0.130
cancer DOID:162 0 0.065