Drosophila melanogaster

0 known processes

CG10376 (Dmel_CG10376)

CG10376 gene product from transcript CG10376-RA

(Aliases: PP2C,Dmel\CG10376)

CG10376 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 372 0.166
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.153
post embryonic appendage morphogenesis GO:0035120 385 0.148
small molecule metabolic process GO:0044281 305 0.147
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.145
death GO:0016265 284 0.139
Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.134
Rat
intracellular signal transduction GO:0035556 300 0.122
compound eye morphogenesis GO:0001745 249 0.117
eye morphogenesis GO:0048592 260 0.116
heterocycle catabolic process GO:0046700 166 0.110
r7 cell differentiation GO:0045466 43 0.107
nucleobase containing compound catabolic process GO:0034655 165 0.105
cell death GO:0008219 279 0.096
Rat
vesicle mediated transport GO:0016192 381 0.094
glycosyl compound catabolic process GO:1901658 112 0.094
positive regulation of gene expression GO:0010628 290 0.091
regulation of multicellular organismal development GO:2000026 414 0.087
positive regulation of response to stimulus GO:0048584 323 0.086
regulation of intracellular signal transduction GO:1902531 236 0.085
endocytosis GO:0006897 310 0.084
epithelial cell differentiation GO:0030855 322 0.084
epithelial cell development GO:0002064 274 0.083
regulation of catalytic activity GO:0050790 185 0.083
Human Rat
response to organic substance GO:0010033 284 0.082
catabolic process GO:0009056 409 0.079
positive regulation of cell communication GO:0010647 250 0.078
positive regulation of rna biosynthetic process GO:1902680 266 0.078
amine metabolic process GO:0009308 12 0.076
positive regulation of signaling GO:0023056 243 0.075
cellular nitrogen compound catabolic process GO:0044270 165 0.074
cellular amine metabolic process GO:0044106 12 0.069
organic cyclic compound catabolic process GO:1901361 168 0.068
taxis GO:0042330 304 0.066
single organism behavior GO:0044708 391 0.065
negative regulation of cell communication GO:0010648 223 0.065
purine containing compound catabolic process GO:0072523 112 0.062
organic substance catabolic process GO:1901575 308 0.061
epithelial cell migration GO:0010631 148 0.061
centrosome organization GO:0051297 163 0.061
wing disc morphogenesis GO:0007472 344 0.061
aromatic compound catabolic process GO:0019439 166 0.061
regulation of localization GO:0032879 275 0.060
regulation of cell development GO:0060284 215 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.059
negative regulation of signaling GO:0023057 219 0.059
compound eye development GO:0048749 307 0.058
cellular macromolecule localization GO:0070727 220 0.057
positive regulation of rna metabolic process GO:0051254 271 0.056
oxoacid metabolic process GO:0043436 103 0.054
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.054
transcription from rna polymerase ii promoter GO:0006366 368 0.054
spermatid differentiation GO:0048515 114 0.054
glycosyl compound metabolic process GO:1901657 127 0.054
regulation of cell differentiation GO:0045595 302 0.053
purine ribonucleoside metabolic process GO:0046128 127 0.052
cation transport GO:0006812 110 0.051
imaginal disc derived appendage morphogenesis GO:0035114 395 0.050
organelle assembly GO:0070925 198 0.050
eye development GO:0001654 323 0.050
spermatogenesis GO:0007283 200 0.049
regulation of nervous system development GO:0051960 248 0.049
negative regulation of neurogenesis GO:0050768 53 0.049
growth GO:0040007 359 0.049
regulation of cellular ketone metabolic process GO:0010565 3 0.048
regulation of cell death GO:0010941 173 0.047
Rat
programmed cell death GO:0012501 257 0.047
Rat
negative regulation of multicellular organismal process GO:0051241 142 0.047
regulation of apoptotic process GO:0042981 130 0.047
Rat
positive regulation of signal transduction GO:0009967 223 0.047
cellular amino acid metabolic process GO:0006520 61 0.046
protein localization GO:0008104 284 0.046
nucleobase containing small molecule metabolic process GO:0055086 174 0.046
tissue migration GO:0090130 155 0.046
regulation of programmed cell death GO:0043067 152 0.046
Rat
carbohydrate derivative metabolic process GO:1901135 217 0.046
carboxylic acid metabolic process GO:0019752 92 0.045
regulation of cellular amine metabolic process GO:0033238 3 0.045
long term memory GO:0007616 62 0.045
response to other organism GO:0051707 293 0.044
response to external biotic stimulus GO:0043207 293 0.044
wnt signaling pathway GO:0016055 98 0.044
regulation of phosphate metabolic process GO:0019220 210 0.044
Human
memory GO:0007613 94 0.043
regulation of cellular amino acid metabolic process GO:0006521 0 0.043
positive regulation of cellular biosynthetic process GO:0031328 316 0.043
cellular response to chemical stimulus GO:0070887 199 0.042
Human
organonitrogen compound metabolic process GO:1901564 318 0.042
nucleotide metabolic process GO:0009117 161 0.042
immune system process GO:0002376 347 0.042
ameboidal type cell migration GO:0001667 151 0.041
neurological system process GO:0050877 358 0.041
negative regulation of signal transduction GO:0009968 206 0.041
transmembrane transport GO:0055085 139 0.040
positive regulation of transcription dna templated GO:0045893 266 0.039
response to radiation GO:0009314 155 0.039
regulation of photoreceptor cell differentiation GO:0046532 34 0.038
dendrite development GO:0016358 204 0.038
protein complex assembly GO:0006461 200 0.037
developmental pigmentation GO:0048066 68 0.037
regulation of hydrolase activity GO:0051336 97 0.037
Rat
eye pigmentation GO:0048069 43 0.036
ion transmembrane transport GO:0034220 122 0.036
negative regulation of nervous system development GO:0051961 92 0.035
regulation of neuron differentiation GO:0045664 103 0.035
lateral inhibition GO:0046331 206 0.035
eye photoreceptor cell differentiation GO:0001754 145 0.035
carbohydrate derivative catabolic process GO:1901136 118 0.035
regulation of molecular function GO:0065009 217 0.034
Human Rat
negative regulation of response to stimulus GO:0048585 258 0.034
compound eye photoreceptor cell differentiation GO:0001751 140 0.033
small gtpase mediated signal transduction GO:0007264 88 0.033
microtubule organizing center organization GO:0031023 168 0.033
cytoplasmic transport GO:0016482 130 0.032
organic substance transport GO:0071702 257 0.032
purine nucleoside triphosphate catabolic process GO:0009146 108 0.032
regulation of epithelial cell proliferation GO:0050678 4 0.032
nucleoside phosphate catabolic process GO:1901292 110 0.032
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.031
imaginal disc derived wing morphogenesis GO:0007476 337 0.031
nucleotide catabolic process GO:0009166 109 0.030
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.030
organic acid metabolic process GO:0006082 103 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
positive regulation of cell death GO:0010942 69 0.030
Rat
regulation of small gtpase mediated signal transduction GO:0051056 93 0.030
positive regulation of phosphate metabolic process GO:0045937 139 0.030
epidermal growth factor receptor signaling pathway GO:0007173 58 0.030
carotenoid metabolic process GO:0016116 1 0.030
synaptic transmission GO:0007268 288 0.029
developmental growth GO:0048589 280 0.029
regulation of anatomical structure size GO:0090066 163 0.029
organonitrogen compound catabolic process GO:1901565 128 0.029
defense response to bacterium GO:0042742 178 0.029
establishment of localization in cell GO:0051649 402 0.029
tor signaling GO:0031929 32 0.029
mapk cascade GO:0000165 107 0.029
nucleoside catabolic process GO:0009164 112 0.029
appendage morphogenesis GO:0035107 397 0.029
response to ionizing radiation GO:0010212 32 0.029
cell motility GO:0048870 251 0.028
nucleoside metabolic process GO:0009116 127 0.028
maintenance of location GO:0051235 73 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
phagocytosis GO:0006909 215 0.028
purine ribonucleotide metabolic process GO:0009150 145 0.028
purine nucleoside triphosphate metabolic process GO:0009144 119 0.027
single organism catabolic process GO:0044712 228 0.027
ribonucleoside triphosphate metabolic process GO:0009199 119 0.027
regulation of transport GO:0051049 181 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
response to nutrient levels GO:0031667 114 0.027
ribonucleoside metabolic process GO:0009119 127 0.027
chemical homeostasis GO:0048878 92 0.026
negative regulation of cell differentiation GO:0045596 143 0.026
compound eye photoreceptor fate commitment GO:0001752 36 0.025
apoptotic process GO:0006915 159 0.025
Rat
regulation of catabolic process GO:0009894 170 0.025
ribonucleoside catabolic process GO:0042454 112 0.025
sensory organ morphogenesis GO:0090596 260 0.025
response to biotic stimulus GO:0009607 294 0.025
actin filament based process GO:0030029 220 0.024
Human
gtp metabolic process GO:0046039 72 0.024
positive regulation of phosphorus metabolic process GO:0010562 139 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
guanosine containing compound metabolic process GO:1901068 74 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.024
negative regulation of immune system process GO:0002683 50 0.024
positive regulation of cellular protein metabolic process GO:0032270 118 0.024
Rat
cell migration GO:0016477 238 0.024
appendage development GO:0048736 401 0.024
ras protein signal transduction GO:0007265 88 0.024
border follicle cell migration GO:0007298 113 0.023
regulation of phosphorylation GO:0042325 147 0.023
Human
negative regulation of developmental process GO:0051093 201 0.023
lipid metabolic process GO:0006629 121 0.023
organelle localization GO:0051640 148 0.023
cellular response to lipopolysaccharide GO:0071222 3 0.023
regulation of neurogenesis GO:0050767 158 0.023
purine nucleoside catabolic process GO:0006152 112 0.023
cellular ketone metabolic process GO:0042180 24 0.023
purine containing compound metabolic process GO:0072521 155 0.023
germ line stem cell maintenance GO:0030718 50 0.023
positive regulation of transport GO:0051050 92 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
epithelium migration GO:0090132 148 0.022
cellular response to organic substance GO:0071310 132 0.022
positive regulation of phosphorylation GO:0042327 87 0.022
response to monosaccharide GO:0034284 4 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
Human
ovarian follicle cell development GO:0030707 248 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
photoreceptor cell differentiation GO:0046530 170 0.021
regulation of wnt signaling pathway GO:0030111 68 0.021
organophosphate metabolic process GO:0019637 195 0.021
response to bacterium GO:0009617 198 0.021
regulation of organ morphogenesis GO:2000027 78 0.021
macromolecular complex assembly GO:0065003 256 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
Human
erbb signaling pathway GO:0038127 58 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
response to abiotic stimulus GO:0009628 341 0.020
regulation of vesicle mediated transport GO:0060627 59 0.020
phosphorylation GO:0016310 294 0.020
Human
ribonucleotide catabolic process GO:0009261 109 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
regulation of mrna processing GO:0050684 71 0.020
regulation of endocytosis GO:0030100 37 0.020
negative regulation of wnt signaling pathway GO:0030178 28 0.020
biological adhesion GO:0022610 138 0.020
actin cytoskeleton organization GO:0030036 206 0.020
Human
positive regulation of apoptotic process GO:0043065 47 0.020
Rat
macromolecule catabolic process GO:0009057 161 0.020
ion transport GO:0006811 145 0.019
extrinsic apoptotic signaling pathway GO:0097191 1 0.019
positive regulation of cellular catabolic process GO:0031331 95 0.019
localization of cell GO:0051674 257 0.019
pigmentation GO:0043473 75 0.019
metal ion transport GO:0030001 74 0.019
regulation of r7 cell differentiation GO:0045676 15 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
Human Rat
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
muscle organ development GO:0007517 127 0.018
intracellular transport GO:0046907 228 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
Rat
nucleoside phosphate metabolic process GO:0006753 162 0.018
gtp catabolic process GO:0006184 72 0.018
rho protein signal transduction GO:0007266 14 0.018
positive regulation of protein modification process GO:0031401 58 0.018
nucleoside triphosphate metabolic process GO:0009141 120 0.018
organic hydroxy compound metabolic process GO:1901615 83 0.018
regulation of developmental growth GO:0048638 174 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
rrna processing GO:0006364 3 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
cellularization GO:0007349 90 0.017
cellular protein modification process GO:0006464 438 0.017
Human Mouse Rat
response to hexose GO:0009746 3 0.017
membrane organization GO:0061024 112 0.017
regulation of protein metabolic process GO:0051246 256 0.017
Human Rat
defense response to other organism GO:0098542 225 0.017
cation transmembrane transport GO:0098655 88 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
Human
synapse organization GO:0050808 196 0.017
posttranscriptional gene silencing GO:0016441 46 0.017
stem cell differentiation GO:0048863 117 0.016
single organism intracellular transport GO:1902582 207 0.016
regulation of cellular localization GO:0060341 136 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
cellular homeostasis GO:0019725 80 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
regulation of growth GO:0040008 233 0.016
stress activated protein kinase signaling cascade GO:0031098 55 0.016
cellular response to endogenous stimulus GO:0071495 80 0.016
organelle fission GO:0048285 340 0.015
stem cell maintenance GO:0019827 67 0.015
regulation of erbb signaling pathway GO:1901184 42 0.015
response to glucose GO:0009749 2 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
response to starvation GO:0042594 97 0.015
response to extracellular stimulus GO:0009991 116 0.015
body morphogenesis GO:0010171 2 0.015
apoptotic cell clearance GO:0043277 14 0.015
cellular response to growth factor stimulus GO:0071363 30 0.015
regulation of synapse organization GO:0050807 110 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
regulation of protein phosphorylation GO:0001932 64 0.015
Human
cellular response to molecule of bacterial origin GO:0071219 3 0.014
regulation of response to stress GO:0080134 200 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
single organism membrane organization GO:0044802 93 0.014
regulation of cell proliferation GO:0042127 163 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
cellular response to light stimulus GO:0071482 37 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
Human
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
signal transduction in response to dna damage GO:0042770 3 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
peptidyl amino acid modification GO:0018193 105 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
neuron projection guidance GO:0097485 241 0.013
positive regulation of catabolic process GO:0009896 105 0.013
chemotaxis GO:0006935 249 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
male gamete generation GO:0048232 201 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
Human
response to lipopolysaccharide GO:0032496 4 0.013
regulation of hormone levels GO:0010817 40 0.013
cilium assembly GO:0042384 38 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
muscle structure development GO:0061061 224 0.013
cellular response to radiation GO:0071478 52 0.013
establishment of protein localization GO:0045184 163 0.013
positive regulation of molecular function GO:0044093 136 0.013
Rat
posttranscriptional gene silencing by rna GO:0035194 45 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
pigment biosynthetic process GO:0046148 36 0.012
mitochondrion organization GO:0007005 65 0.012
regulation of cellular response to stress GO:0080135 89 0.012
regulation of cell shape GO:0008360 113 0.012
autophagy GO:0006914 108 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
one carbon metabolic process GO:0006730 3 0.012
organophosphate catabolic process GO:0046434 112 0.012
cognition GO:0050890 141 0.012
histolysis GO:0007559 102 0.012
torc1 signaling GO:0038202 12 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
telencephalon development GO:0021537 2 0.012
response to oxygen containing compound GO:1901700 200 0.012
cell proliferation GO:0008283 299 0.012
nuclear division GO:0000280 332 0.012
cellular response to starvation GO:0009267 61 0.011
positive regulation of protein phosphorylation GO:0001934 34 0.011
protein transport GO:0015031 155 0.011
positive regulation of nucleotide catabolic process GO:0030813 46 0.011
single organism cellular localization GO:1902580 180 0.011
negative regulation of erbb signaling pathway GO:1901185 29 0.011
ion homeostasis GO:0050801 55 0.011
single organism biosynthetic process GO:0044711 206 0.011
regulation of purine nucleotide catabolic process GO:0033121 48 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
r7 cell fate commitment GO:0007465 12 0.011
tissue death GO:0016271 102 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of gtp catabolic process GO:0033124 44 0.011
dendrite morphogenesis GO:0048813 199 0.011
dna metabolic process GO:0006259 227 0.011
protein modification process GO:0036211 438 0.011
Human Mouse Rat
response to endogenous stimulus GO:0009719 119 0.011
positive regulation of lipid metabolic process GO:0045834 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
jak stat cascade GO:0007259 49 0.011
axon development GO:0061564 297 0.011
protein complex biogenesis GO:0070271 201 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
Rat
retina development in camera type eye GO:0060041 4 0.010
regulation of transferase activity GO:0051338 58 0.010
Human
positive regulation of multicellular organismal process GO:0051240 143 0.010
salivary gland histolysis GO:0035070 88 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
forebrain development GO:0030900 2 0.010
axonogenesis GO:0007409 290 0.010
regulation of ion transport GO:0043269 39 0.010

CG10376 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.020
disease of anatomical entity DOID:7 0 0.016
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
nervous system disease DOID:863 0 0.016