Drosophila melanogaster

28 known processes

Nha1 (Dmel_CG10806)

Na[+]/H[+] hydrogen antiporter 1

(Aliases: CG10806,DmNHA1,Dmel\CG10806)

Nha1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.046
response to lipopolysaccharide GO:0032496 4 0.042
response to organic substance GO:0010033 284 0.041
organonitrogen compound metabolic process GO:1901564 318 0.035
single organism behavior GO:0044708 391 0.032
regionalization GO:0003002 416 0.031
l glutamate import GO:0051938 1 0.031
response to external biotic stimulus GO:0043207 293 0.030
response to alcohol GO:0097305 95 0.030
response to oxygen containing compound GO:1901700 200 0.030
carboxylic acid metabolic process GO:0019752 92 0.029
organic acid metabolic process GO:0006082 103 0.029
organic substance catabolic process GO:1901575 308 0.029
vesicle mediated transport GO:0016192 381 0.029
catabolic process GO:0009056 409 0.029
response to biotic stimulus GO:0009607 294 0.028
oxoacid metabolic process GO:0043436 103 0.027
organic substance transport GO:0071702 257 0.027
Fly
response to nutrient levels GO:0031667 114 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
single organism biosynthetic process GO:0044711 206 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
body morphogenesis GO:0010171 2 0.025
response to other organism GO:0051707 293 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
nuclear division GO:0000280 332 0.025
cellular catabolic process GO:0044248 372 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
response to organonitrogen compound GO:0010243 75 0.024
positive regulation of cell communication GO:0010647 250 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
regulation of localization GO:0032879 275 0.023
establishment of localization in cell GO:0051649 402 0.023
Fly
positive regulation of transcription dna templated GO:0045893 266 0.022
intracellular signal transduction GO:0035556 300 0.022
organelle fission GO:0048285 340 0.022
response to extracellular stimulus GO:0009991 116 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
positive regulation of signaling GO:0023056 243 0.022
response to monosaccharide GO:0034284 4 0.021
forebrain development GO:0030900 2 0.021
single organism catabolic process GO:0044712 228 0.021
dephosphorylation GO:0016311 51 0.021
phosphate ion transport GO:0006817 4 0.020
appendage development GO:0048736 401 0.020
locomotory behavior GO:0007626 176 0.020
protein modification process GO:0036211 438 0.020
sodium dependent phosphate transport GO:0044341 2 0.020
response to endogenous stimulus GO:0009719 119 0.020
compound eye development GO:0048749 307 0.020
cellular protein modification process GO:0006464 438 0.020
positive regulation of biosynthetic process GO:0009891 316 0.019
homeostatic process GO:0042592 199 0.019
connective tissue development GO:0061448 3 0.019
response to abiotic stimulus GO:0009628 341 0.019
kidney development GO:0001822 3 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
response to organophosphorus GO:0046683 2 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
response to bacterium GO:0009617 198 0.019
camera type eye development GO:0043010 4 0.019
phosphorylation GO:0016310 294 0.018
developmental programmed cell death GO:0010623 138 0.018
positive regulation of cell migration GO:0030335 2 0.018
neurological system process GO:0050877 358 0.018
positive regulation of signal transduction GO:0009967 223 0.018
eye development GO:0001654 323 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
phagocytosis GO:0006909 215 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
appendage morphogenesis GO:0035107 397 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
endocytosis GO:0006897 310 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
positive regulation of cell motility GO:2000147 3 0.017
positive regulation of gene expression GO:0010628 290 0.017
cellular ketone metabolic process GO:0042180 24 0.017
nucleotide metabolic process GO:0009117 161 0.017
salivary gland development GO:0007431 162 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
macromolecular complex assembly GO:0065003 256 0.017
regulation of cell differentiation GO:0045595 302 0.017
response to glucose GO:0009749 2 0.017
wing disc morphogenesis GO:0007472 344 0.017
compound eye morphogenesis GO:0001745 249 0.017
intracellular transport GO:0046907 228 0.017
cell proliferation GO:0008283 299 0.017
protein localization GO:0008104 284 0.017
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
lateral inhibition GO:0046331 206 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
cell death GO:0008219 279 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
exocrine system development GO:0035272 162 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
telencephalon development GO:0021537 2 0.016
single organism intracellular transport GO:1902582 207 0.016
developmental maturation GO:0021700 172 0.016
l amino acid import GO:0043092 2 0.016
response to nitrogen compound GO:1901698 90 0.016
ras protein signal transduction GO:0007265 88 0.016
organophosphate metabolic process GO:0019637 195 0.016
regulation of molecular function GO:0065009 217 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
amine metabolic process GO:0009308 12 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
macromolecule catabolic process GO:0009057 161 0.015
epithelial cell development GO:0002064 274 0.015
estrogen metabolic process GO:0008210 1 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
mitotic nuclear division GO:0007067 213 0.015
regulation of cell cycle GO:0051726 291 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
regulation of response to stress GO:0080134 200 0.015
response to hexose GO:0009746 3 0.015
negative regulation of gene expression GO:0010629 387 0.015
response to light stimulus GO:0009416 124 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
nitrogen compound transport GO:0071705 85 0.015
gland morphogenesis GO:0022612 145 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
chromosome organization GO:0051276 360 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
tube morphogenesis GO:0035239 191 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
open tracheal system development GO:0007424 204 0.015
death GO:0016265 284 0.015
ion transmembrane transport GO:0034220 122 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
ion transport GO:0006811 145 0.015
regulation of catabolic process GO:0009894 170 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
multicellular organismal aging GO:0010259 140 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
taxis GO:0042330 304 0.014
regulation of catalytic activity GO:0050790 185 0.014
detection of stimulus GO:0051606 156 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
heterocycle catabolic process GO:0046700 166 0.014
protein complex biogenesis GO:0070271 201 0.014
pigmentation GO:0043473 75 0.014
immune response activating signal transduction GO:0002757 2 0.014
purine containing compound metabolic process GO:0072521 155 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
epithelial cell differentiation GO:0030855 322 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
regulation of programmed cell death GO:0043067 152 0.014
mesenchymal cell development GO:0014031 1 0.014
eye morphogenesis GO:0048592 260 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
programmed cell death GO:0012501 257 0.014
cellular response to ethanol GO:0071361 4 0.014
aromatic compound catabolic process GO:0019439 166 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
tissue death GO:0016271 102 0.014
cellular response to hexose stimulus GO:0071331 1 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
rna localization GO:0006403 115 0.013
regulation of protein metabolic process GO:0051246 256 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
mrna metabolic process GO:0016071 124 0.013
cellular amine metabolic process GO:0044106 12 0.013
nucleoside metabolic process GO:0009116 127 0.013
pigment metabolic process involved in pigmentation GO:0043474 33 0.013
salivary gland morphogenesis GO:0007435 145 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
spindle organization GO:0007051 253 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
segmentation GO:0035282 207 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of transport GO:0051049 181 0.013
regulation of cellular localization GO:0060341 136 0.013
autophagic cell death GO:0048102 83 0.013
regulation of cell death GO:0010941 173 0.013
cytoplasmic transport GO:0016482 130 0.013
cellular response to monosaccharide stimulus GO:0071326 2 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
steroid catabolic process GO:0006706 1 0.013
transmembrane transport GO:0055085 139 0.013
activation of innate immune response GO:0002218 4 0.013
pyridine containing compound metabolic process GO:0072524 3 0.013
sensory organ morphogenesis GO:0090596 260 0.013
salivary gland histolysis GO:0035070 88 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
gland development GO:0048732 191 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
anion transport GO:0006820 41 0.013
embryonic pattern specification GO:0009880 174 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
establishment of protein localization GO:0045184 163 0.012
Fly
ribonucleoside catabolic process GO:0042454 112 0.012
aging GO:0007568 143 0.012
proteolysis GO:0006508 192 0.012
androgen metabolic process GO:0008209 1 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
regulation of organelle organization GO:0033043 196 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
endomembrane system organization GO:0010256 119 0.012
cell cycle phase transition GO:0044770 140 0.012
tissue morphogenesis GO:0048729 297 0.012
imaginal disc pattern formation GO:0007447 91 0.012
meiotic cell cycle GO:0051321 171 0.012
ovarian follicle cell development GO:0030707 248 0.012
limb development GO:0060173 1 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
monocarboxylic acid transport GO:0015718 3 0.012
regulation of cellular response to stress GO:0080135 89 0.012
negative regulation of developmental process GO:0051093 201 0.012
nucleoside catabolic process GO:0009164 112 0.012
regulation of nervous system development GO:0051960 248 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
xenobiotic catabolic process GO:0042178 1 0.012
mrna processing GO:0006397 104 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
adult behavior GO:0030534 137 0.012
secretion GO:0046903 109 0.012
Fly
cellular macromolecule localization GO:0070727 220 0.012
chromosome segregation GO:0007059 157 0.012
response to radiation GO:0009314 155 0.012
cell division GO:0051301 248 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
synaptic transmission GO:0007268 288 0.012
notch signaling pathway GO:0007219 120 0.012
wing disc pattern formation GO:0035222 66 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
protein transport GO:0015031 155 0.012
Fly
protein catabolic process GO:0030163 101 0.011
sensory perception GO:0007600 196 0.011
histolysis GO:0007559 102 0.011
eye pigment metabolic process GO:0042441 33 0.011
hormone catabolic process GO:0042447 3 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
leg disc development GO:0035218 92 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
wnt signaling pathway GO:0016055 98 0.011
multi organism behavior GO:0051705 175 0.011
pigment biosynthetic process GO:0046148 36 0.011
jak stat cascade GO:0007259 49 0.011
neuron projection guidance GO:0097485 241 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
regulation of cell cycle process GO:0010564 181 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
camera type eye morphogenesis GO:0048593 2 0.011
positive regulation of catabolic process GO:0009896 105 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
golgi organization GO:0007030 66 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
cholesterol homeostasis GO:0042632 3 0.011
lipid metabolic process GO:0006629 121 0.011
regulation of cell proliferation GO:0042127 163 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
purine containing compound catabolic process GO:0072523 112 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
pyridine nucleotide metabolic process GO:0019362 2 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
regulation of cell development GO:0060284 215 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
nicotinamide nucleotide metabolic process GO:0046496 2 0.011
cell maturation GO:0048469 144 0.011
blastoderm segmentation GO:0007350 159 0.011
protein complex assembly GO:0006461 200 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
response to lipid GO:0033993 38 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
rna processing GO:0006396 147 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
axis specification GO:0009798 167 0.011
positive regulation of molecular function GO:0044093 136 0.011
mapk cascade GO:0000165 107 0.011
developmental growth GO:0048589 280 0.011
developmental pigmentation GO:0048066 68 0.011
kidney epithelium development GO:0072073 3 0.011
sister chromatid segregation GO:0000819 92 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
single organism cellular localization GO:1902580 180 0.011
regulation of mapk cascade GO:0043408 92 0.011
adult locomotory behavior GO:0008344 76 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
regulation of rna splicing GO:0043484 69 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
organophosphate catabolic process GO:0046434 112 0.010
growth GO:0040007 359 0.010
organelle assembly GO:0070925 198 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
chemotaxis GO:0006935 249 0.010
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
central nervous system development GO:0007417 201 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
sterol homeostasis GO:0055092 4 0.010
chaeta development GO:0022416 97 0.010
limb morphogenesis GO:0035108 1 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
modification dependent protein catabolic process GO:0019941 78 0.010
anion homeostasis GO:0055081 3 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
secretion by cell GO:0032940 101 0.010
Fly
positive regulation of transport GO:0051050 92 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
apoptotic process GO:0006915 159 0.010
cellular protein catabolic process GO:0044257 83 0.010
cellular homeostasis GO:0019725 80 0.010
immune response GO:0006955 246 0.010
meiotic nuclear division GO:0007126 151 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
cellular response to organic substance GO:0071310 132 0.010
imaginal disc derived leg morphogenesis GO:0007480 80 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
mitotic spindle organization GO:0007052 220 0.010
hindbrain development GO:0030902 2 0.010
retina development in camera type eye GO:0060041 4 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
actin cytoskeleton organization GO:0030036 206 0.010
cellular lipid metabolic process GO:0044255 83 0.010
negative regulation of signal transduction GO:0009968 206 0.010
detection of external stimulus GO:0009581 66 0.010
nephron development GO:0072006 3 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010

Nha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.013
cardiovascular system disease DOID:1287 0 0.013
urinary system disease DOID:18 0 0.013
sensory system disease DOID:0050155 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
kidney disease DOID:557 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
diabetes mellitus DOID:9351 0 0.011
type 2 diabetes mellitus DOID:9352 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
acquired metabolic disease DOID:0060158 0 0.011
organ system cancer DOID:0050686 0 0.010