Drosophila melanogaster

171 known processes

Rca1 (Dmel_CG10800)

Regulator of cyclin A1

(Aliases: l(2)03300,CLD4,Dmel\CG10800,P3300,rca1,152549_at,CG10800,Emi1,RCA1,S(rux)2A)

Rca1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.991
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.840
regulation of neurogenesis GO:0050767 158 0.822
transcription from rna polymerase ii promoter GO:0006366 368 0.811
intracellular signal transduction GO:0035556 300 0.790
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.749
neuroblast proliferation GO:0007405 74 0.712
tissue morphogenesis GO:0048729 297 0.682
cellular response to dna damage stimulus GO:0006974 223 0.579
negative regulation of developmental process GO:0051093 201 0.490
negative regulation of transcription dna templated GO:0045892 237 0.485
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.472
positive regulation of gene expression GO:0010628 290 0.472
cell proliferation GO:0008283 299 0.447
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.446
chromatin modification GO:0016568 147 0.440
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.430
regulation of protein metabolic process GO:0051246 256 0.414
positive regulation of macromolecule metabolic process GO:0010604 405 0.407
regulation of organelle organization GO:0033043 196 0.392
negative regulation of cellular biosynthetic process GO:0031327 277 0.380
regulation of molecular function GO:0065009 217 0.355
morphogenesis of an epithelium GO:0002009 276 0.350
negative regulation of neurogenesis GO:0050768 53 0.347
negative regulation of nucleic acid templated transcription GO:1903507 240 0.342
negative regulation of rna biosynthetic process GO:1902679 240 0.325
chromatin organization GO:0006325 207 0.316
negative regulation of neuroblast proliferation GO:0007406 27 0.291
sister chromatid segregation GO:0000819 92 0.276
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.271
programmed cell death GO:0012501 257 0.265
neural precursor cell proliferation GO:0061351 75 0.258
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.256
organelle assembly GO:0070925 198 0.254
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.252
heart development GO:0007507 82 0.252
regulation of cell cycle phase transition GO:1901987 130 0.233
cell cycle phase transition GO:0044770 140 0.230
oocyte maturation GO:0001556 3 0.226
Mouse
axon development GO:0061564 297 0.221
negative regulation of rna metabolic process GO:0051253 251 0.215
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.213
regulation of chromosome organization GO:0033044 64 0.212
small gtpase mediated signal transduction GO:0007264 88 0.205
apoptotic process GO:0006915 159 0.205
death GO:0016265 284 0.204
regulation of multicellular organismal development GO:2000026 414 0.199
mitotic cell cycle phase transition GO:0044772 138 0.181
positive regulation of rna metabolic process GO:0051254 271 0.169
positive regulation of cellular biosynthetic process GO:0031328 316 0.169
dna replication GO:0006260 48 0.169
regulation of mitotic cell cycle phase transition GO:1901990 130 0.169
regulation of cell development GO:0060284 215 0.168
positive regulation of signaling GO:0023056 243 0.166
regulation of neuroblast proliferation GO:1902692 34 0.163
respiratory system development GO:0060541 213 0.161
lateral inhibition GO:0046331 206 0.161
negative regulation of cell cycle GO:0045786 116 0.157
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.153
mitotic sister chromatid segregation GO:0000070 87 0.147
chromosome segregation GO:0007059 157 0.144
regulation of mitotic sister chromatid segregation GO:0033047 28 0.141
positive regulation of biosynthetic process GO:0009891 316 0.139
tube development GO:0035295 244 0.133
axonogenesis GO:0007409 290 0.132
negative regulation of gene expression GO:0010629 387 0.131
regulation of cell differentiation GO:0045595 302 0.131
dna biosynthetic process GO:0071897 24 0.131
regulation of anatomical structure morphogenesis GO:0022603 242 0.128
dna metabolic process GO:0006259 227 0.125
positive regulation of protein metabolic process GO:0051247 128 0.121
regulation of dendrite development GO:0050773 37 0.120
dna endoreduplication GO:0042023 22 0.120
eye morphogenesis GO:0048592 260 0.117
positive regulation of cellular protein metabolic process GO:0032270 118 0.113
negative regulation of biosynthetic process GO:0009890 277 0.113
positive regulation of rna biosynthetic process GO:1902680 266 0.113
positive regulation of nucleic acid templated transcription GO:1903508 266 0.112
regulation of mitotic cell cycle GO:0007346 190 0.112
stem cell differentiation GO:0048863 117 0.106
dendrite morphogenesis GO:0048813 199 0.099
protein ubiquitination GO:0016567 70 0.099
circulatory system development GO:0072359 82 0.094
positive regulation of transcription dna templated GO:0045893 266 0.093
negative regulation of cell proliferation GO:0008285 69 0.092
mitotic sister chromatid separation GO:0051306 30 0.089
macromolecule catabolic process GO:0009057 161 0.086
regulation of ras protein signal transduction GO:0046578 93 0.086
organelle fission GO:0048285 340 0.086
cell death GO:0008219 279 0.086
eye development GO:0001654 323 0.085
cell adhesion GO:0007155 136 0.082
ras protein signal transduction GO:0007265 88 0.079
embryo development ending in birth or egg hatching GO:0009792 152 0.079
regulation of protein transport GO:0051223 57 0.079
stem cell proliferation GO:0072089 88 0.074
cell cycle checkpoint GO:0000075 95 0.073
regulation of nervous system development GO:0051960 248 0.070
positive regulation of cellular component organization GO:0051130 156 0.070
growth GO:0040007 359 0.070
regulation of cell cycle GO:0051726 291 0.065
positive regulation of molecular function GO:0044093 136 0.065
regulation of intracellular signal transduction GO:1902531 236 0.064
cellular protein modification process GO:0006464 438 0.063
regulation of cellular protein metabolic process GO:0032268 243 0.063
regulation of chromatin organization GO:1902275 32 0.062
histone modification GO:0016570 106 0.062
regulation of cell morphogenesis GO:0022604 163 0.059
negative regulation of cell cycle phase transition GO:1901988 103 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
dendrite development GO:0016358 204 0.057
larval development GO:0002164 104 0.057
protein modification process GO:0036211 438 0.056
development of primary sexual characteristics GO:0045137 50 0.053
negative regulation of cell differentiation GO:0045596 143 0.053
developmental growth GO:0048589 280 0.052
cellular macromolecule catabolic process GO:0044265 136 0.051
regulation of protein modification process GO:0031399 112 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.051
proteasomal protein catabolic process GO:0010498 59 0.051
regulation of cell death GO:0010941 173 0.048
catabolic process GO:0009056 409 0.048
phosphorylation GO:0016310 294 0.048
chromosome separation GO:0051304 42 0.048
protein phosphorylation GO:0006468 169 0.047
sister chromatid cohesion GO:0007062 18 0.047
negative regulation of nervous system development GO:0051961 92 0.047
negative regulation of response to stimulus GO:0048585 258 0.047
cellular macromolecular complex assembly GO:0034622 153 0.046
Mouse
regulation of sister chromatid segregation GO:0033045 28 0.046
cardiovascular system development GO:0072358 82 0.046
negative regulation of cell development GO:0010721 62 0.046
imaginal disc pattern formation GO:0007447 91 0.045
stem cell development GO:0048864 79 0.044
endocytosis GO:0006897 310 0.043
gliogenesis GO:0042063 80 0.042
organic substance catabolic process GO:1901575 308 0.040
camera type eye development GO:0043010 4 0.040
regulation of catalytic activity GO:0050790 185 0.040
developmental maturation GO:0021700 172 0.038
Mouse
oocyte development GO:0048599 124 0.037
Mouse
asymmetric neuroblast division GO:0055059 33 0.037
cell junction organization GO:0034330 57 0.037
cell maturation GO:0048469 144 0.036
Mouse
metaphase anaphase transition of cell cycle GO:0044784 28 0.036
regulation of neural precursor cell proliferation GO:2000177 35 0.036
appendage development GO:0048736 401 0.036
regulation of neuron differentiation GO:0045664 103 0.036
regulation of small gtpase mediated signal transduction GO:0051056 93 0.035
negative regulation of growth GO:0045926 84 0.035
muscle cell development GO:0055001 50 0.034
macromolecular complex assembly GO:0065003 256 0.033
Mouse
regulation of cell proliferation GO:0042127 163 0.033
nuclear division GO:0000280 332 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.032
stem cell division GO:0017145 69 0.032
protein modification by small protein conjugation GO:0032446 79 0.032
telomere organization GO:0032200 21 0.032
positive regulation of catabolic process GO:0009896 105 0.032
mrna splice site selection GO:0006376 1 0.031
regulation of mitotic sister chromatid separation GO:0010965 28 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
embryonic morphogenesis GO:0048598 206 0.031
positive regulation of response to stimulus GO:0048584 323 0.030
negative regulation of cellular component organization GO:0051129 108 0.030
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.029
muscle cell differentiation GO:0042692 103 0.029
positive regulation of phosphorylation GO:0042327 87 0.028
imaginal disc derived appendage development GO:0048737 399 0.028
mitotic dna damage checkpoint GO:0044773 74 0.028
neuroblast division GO:0055057 35 0.028
sensory organ morphogenesis GO:0090596 260 0.028
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
oocyte differentiation GO:0009994 145 0.027
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.027
muscle structure development GO:0061061 224 0.027
hematopoietic or lymphoid organ development GO:0048534 57 0.027
Zebrafish
regulation of phosphorylation GO:0042325 147 0.026
positive regulation of cell death GO:0010942 69 0.026
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.026
neuron fate commitment GO:0048663 50 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
positive regulation of chromatin silencing GO:0031937 16 0.026
protein catabolic process GO:0030163 101 0.025
positive regulation of programmed cell death GO:0043068 62 0.025
regulation of cellular localization GO:0060341 136 0.025
regulation of cell division GO:0051302 72 0.024
regulation of cell cycle process GO:0010564 181 0.024
protein dna complex subunit organization GO:0071824 86 0.023
cellular catabolic process GO:0044248 372 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
double strand break repair GO:0006302 26 0.023
intermediate filament cytoskeleton organization GO:0045104 1 0.022
phagocytosis GO:0006909 215 0.022
proteolysis GO:0006508 192 0.022
negative regulation of neural precursor cell proliferation GO:2000178 27 0.022
glial cell differentiation GO:0010001 35 0.021
regulation of growth GO:0040008 233 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
dna conformation change GO:0071103 105 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
dendrite guidance GO:0070983 21 0.021
positive regulation of organelle organization GO:0010638 65 0.021
camera type eye morphogenesis GO:0048593 2 0.020
positive regulation of signal transduction GO:0009967 223 0.020
negative regulation of phosphate metabolic process GO:0045936 45 0.020
neuron projection guidance GO:0097485 241 0.020
compound eye development GO:0048749 307 0.020
body morphogenesis GO:0010171 2 0.020
muscle organ development GO:0007517 127 0.019
germarium derived female germ line cyst formation GO:0030727 42 0.019
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.019
regulation of wnt signaling pathway GO:0030111 68 0.019
positive regulation of protein modification process GO:0031401 58 0.019
axon guidance GO:0007411 233 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
meiotic cell cycle phase transition GO:0044771 4 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
neurological system process GO:0050877 358 0.018
response to alcohol GO:0097305 95 0.018
dna templated transcription elongation GO:0006354 18 0.018
regulation of intracellular protein transport GO:0033157 46 0.018
embryonic development via the syncytial blastoderm GO:0001700 148 0.018
mitotic nuclear division GO:0007067 213 0.018
covalent chromatin modification GO:0016569 106 0.017
positive regulation of cell communication GO:0010647 250 0.017
regulation of neuron projection development GO:0010975 69 0.017
developmental programmed cell death GO:0010623 138 0.017
sensory organ precursor cell division GO:0045035 10 0.017
dna integrity checkpoint GO:0031570 81 0.017
appendage morphogenesis GO:0035107 397 0.017
regulation of hemocyte proliferation GO:0035206 37 0.016
meiosis i GO:0007127 59 0.016
Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
tube morphogenesis GO:0035239 191 0.016
single organism catabolic process GO:0044712 228 0.016
embryonic organ development GO:0048568 50 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
regionalization GO:0003002 416 0.015
reproductive structure development GO:0048608 74 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
regulation of mitosis GO:0007088 56 0.014
genitalia development GO:0048806 26 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
axis specification GO:0009798 167 0.014
mitotic cytokinesis GO:0000281 50 0.013
Zebrafish
organonitrogen compound metabolic process GO:1901564 318 0.013
adherens junction organization GO:0034332 27 0.013
positive regulation of protein catabolic process GO:0045732 34 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
regulation of cytoplasmic transport GO:1903649 47 0.013
regulation of apoptotic process GO:0042981 130 0.013
regulation of chromatin silencing GO:0031935 36 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.012
nuclear export GO:0051168 24 0.012
mitotic sister chromatid cohesion GO:0007064 6 0.012
mrna 3 end processing GO:0031124 28 0.012
response to external biotic stimulus GO:0043207 293 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
regulation of dna recombination GO:0000018 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of programmed cell death GO:0043067 152 0.011
regulation of protein complex disassembly GO:0043244 29 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
tissue death GO:0016271 102 0.011
female germ line cyst formation GO:0048135 42 0.011
retina development in camera type eye GO:0060041 4 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
negative regulation of stem cell proliferation GO:2000647 30 0.011
meiotic cell cycle GO:0051321 171 0.010
Mouse
regulation of gene silencing GO:0060968 63 0.010
chromatin remodeling GO:0006338 72 0.010
aromatic compound catabolic process GO:0019439 166 0.010

Rca1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014