Drosophila melanogaster

67 known processes

Mcm3 (Dmel_CG4206)

Minichromosome maintenance 3

(Aliases: DmMCM3,dMCM3,CG4206,PCR2,DmMcm3,DmeMCM3,MCM3,Mcp-PCR2,Dmel\CG4206,McM3)

Mcm3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
recombinational repair GO:0000725 13 0.767
Yeast
dna replication GO:0006260 48 0.760
Yeast
double strand break repair GO:0006302 26 0.673
Yeast
dna geometric change GO:0032392 16 0.665
mitotic dna integrity checkpoint GO:0044774 75 0.663
dna repair GO:0006281 54 0.657
Yeast
double strand break repair via nonhomologous end joining GO:0006303 5 0.622
mitotic dna damage checkpoint GO:0044773 74 0.580
dna recombination GO:0006310 32 0.503
Yeast
reciprocal meiotic recombination GO:0007131 19 0.444
mitotic g2 dna damage checkpoint GO:0007095 69 0.433
double strand break repair via homologous recombination GO:0000724 13 0.406
Yeast
translesion synthesis GO:0019985 2 0.374
negative regulation of cell cycle phase transition GO:1901988 103 0.350
dna damage checkpoint GO:0000077 78 0.321
dna metabolic process GO:0006259 227 0.314
g2 dna damage checkpoint GO:0031572 69 0.298
zymogen activation GO:0031638 20 0.242
meiotic chromosome segregation GO:0045132 59 0.235
dna conformation change GO:0071103 105 0.229
cell cycle dna replication GO:0044786 23 0.218
Yeast
regulation of cell cycle GO:0051726 291 0.218
organic substance catabolic process GO:1901575 308 0.212
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.206
chromosome organization GO:0051276 360 0.183
nuclear dna replication GO:0033260 1 0.176
Yeast
dna integrity checkpoint GO:0031570 81 0.171
chromosome segregation GO:0007059 157 0.161
chromosome condensation GO:0030261 41 0.157
regulation of dna metabolic process GO:0051052 34 0.157
non recombinational repair GO:0000726 7 0.155
single organism biosynthetic process GO:0044711 206 0.149
Yeast
dna packaging GO:0006323 91 0.144
heterocycle catabolic process GO:0046700 166 0.138
Yeast
cell cycle checkpoint GO:0000075 95 0.136
regulation of cell cycle process GO:0010564 181 0.131
organelle fission GO:0048285 340 0.129
nuclear division GO:0000280 332 0.128
nucleobase containing compound catabolic process GO:0034655 165 0.127
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.124
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.114
Yeast
positive regulation of peptidase activity GO:0010952 29 0.112
mitotic cell cycle checkpoint GO:0007093 88 0.110
death GO:0016265 284 0.108
mitotic spindle elongation GO:0000022 81 0.107
cell cycle phase transition GO:0044770 140 0.107
mitotic cell cycle phase transition GO:0044772 138 0.094
mitotic g2 m transition checkpoint GO:0044818 70 0.088
negative regulation of cell cycle process GO:0010948 109 0.086
macromolecular complex assembly GO:0065003 256 0.084
Yeast
aromatic compound catabolic process GO:0019439 166 0.083
Yeast
catabolic process GO:0009056 409 0.080
Yeast
single organism intracellular transport GO:1902582 207 0.080
negative regulation of mitotic cell cycle GO:0045930 109 0.078
negative regulation of cellular biosynthetic process GO:0031327 277 0.077
Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.076
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.072
regulation of multicellular organismal development GO:2000026 414 0.071
programmed cell death GO:0012501 257 0.071
endocytosis GO:0006897 310 0.070
negative regulation of nucleic acid templated transcription GO:1903507 240 0.070
Yeast
cellular macromolecule localization GO:0070727 220 0.070
regulation of apoptotic process GO:0042981 130 0.069
postreplication repair GO:0006301 2 0.068
regulation of cellular response to stress GO:0080135 89 0.068
nucleotide excision repair GO:0006289 8 0.068
cellular nitrogen compound catabolic process GO:0044270 165 0.067
Yeast
cell proliferation GO:0008283 299 0.067
cell death GO:0008219 279 0.063
dna replication initiation GO:0006270 6 0.061
Yeast
spindle elongation GO:0051231 83 0.061
negative regulation of cell cycle GO:0045786 116 0.061
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.060
regulation of cell death GO:0010941 173 0.059
phosphorylation GO:0016310 294 0.058
regulation of dna repair GO:0006282 5 0.057
small molecule metabolic process GO:0044281 305 0.057
Yeast
regulation of mitotic cell cycle GO:0007346 190 0.057
cellular catabolic process GO:0044248 372 0.056
Yeast
regulation of cysteine type endopeptidase activity GO:2000116 27 0.056
organic cyclic compound catabolic process GO:1901361 168 0.055
Yeast
vesicle mediated transport GO:0016192 381 0.054
negative regulation of gene expression epigenetic GO:0045814 77 0.053
Yeast
regulation of dna recombination GO:0000018 4 0.051
reciprocal dna recombination GO:0035825 19 0.051
homeostatic process GO:0042592 199 0.050
regulation of programmed cell death GO:0043067 152 0.050
dna dependent dna replication GO:0006261 17 0.050
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
Yeast
mitotic nuclear division GO:0007067 213 0.048
dna double strand break processing GO:0000729 3 0.047
regulation of mitotic cell cycle phase transition GO:1901990 130 0.047
regulation of organelle organization GO:0033043 196 0.046
ribonucleoside metabolic process GO:0009119 127 0.046
Yeast
negative regulation of rna metabolic process GO:0051253 251 0.046
Yeast
ribose phosphate metabolic process GO:0019693 145 0.046
Yeast
cell division GO:0051301 248 0.046
mitotic spindle organization GO:0007052 220 0.045
nucleoside triphosphate metabolic process GO:0009141 120 0.045
Yeast
larval development GO:0002164 104 0.045
meiotic nuclear division GO:0007126 151 0.041
regulation of catabolic process GO:0009894 170 0.040
regulation of cell cycle phase transition GO:1901987 130 0.040
regulation of response to stress GO:0080134 200 0.039
negative regulation of programmed cell death GO:0043069 72 0.038
spindle organization GO:0007051 253 0.038
positive regulation of nucleic acid templated transcription GO:1903508 266 0.037
regulation of cellular protein metabolic process GO:0032268 243 0.037
meiosis i GO:0007127 59 0.037
establishment of localization in cell GO:0051649 402 0.037
cellular macromolecule catabolic process GO:0044265 136 0.036
regulation of cell proliferation GO:0042127 163 0.036
cellular protein complex assembly GO:0043623 71 0.036
regulation of dna replication GO:0006275 13 0.035
organonitrogen compound metabolic process GO:1901564 318 0.034
Yeast
g1 s transition of mitotic cell cycle GO:0000082 31 0.034
response to radiation GO:0009314 155 0.034
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
Yeast
regulation of double strand break repair GO:2000779 3 0.033
dna endoreduplication GO:0042023 22 0.033
regulation of chromosome organization GO:0033044 64 0.033
cellular response to radiation GO:0071478 52 0.032
cell cycle g1 s phase transition GO:0044843 31 0.032
negative regulation of transcription dna templated GO:0045892 237 0.032
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.031
protein dna complex assembly GO:0065004 63 0.031
Yeast
apoptotic process GO:0006915 159 0.031
negative regulation of cellular component organization GO:0051129 108 0.031
regulation of cell division GO:0051302 72 0.030
regulation of cell differentiation GO:0045595 302 0.030
regulation of cellular catabolic process GO:0031329 157 0.030
regulation of meiosis GO:0040020 3 0.030
notch signaling pathway GO:0007219 120 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.030
Yeast
positive regulation of biosynthetic process GO:0009891 316 0.029
macromolecule catabolic process GO:0009057 161 0.029
regulation of phosphate metabolic process GO:0019220 210 0.029
regulation of dna dependent dna replication GO:0090329 6 0.028
ribonucleoside monophosphate metabolic process GO:0009161 51 0.028
Yeast
activation of cysteine type endopeptidase activity GO:0097202 17 0.028
camera type eye development GO:0043010 4 0.028
regulation of molecular function GO:0065009 217 0.028
response to abiotic stimulus GO:0009628 341 0.027
negative regulation of apoptotic process GO:0043066 63 0.027
organonitrogen compound catabolic process GO:1901565 128 0.027
Yeast
meiotic cell cycle GO:0051321 171 0.027
positive regulation of hydrolase activity GO:0051345 78 0.027
regulation of protein complex disassembly GO:0043244 29 0.027
dna duplex unwinding GO:0032508 16 0.027
regulation of cell development GO:0060284 215 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
response to other organism GO:0051707 293 0.026
negative regulation of gene expression GO:0010629 387 0.026
Yeast
body morphogenesis GO:0010171 2 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.024
positive regulation of gene expression GO:0010628 290 0.024
purine containing compound metabolic process GO:0072521 155 0.024
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
Yeast
organophosphate metabolic process GO:0019637 195 0.023
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
Yeast
response to light stimulus GO:0009416 124 0.022
carboxylic acid metabolic process GO:0019752 92 0.021
nucleoside triphosphate catabolic process GO:0009143 108 0.021
Yeast
ribonucleoside catabolic process GO:0042454 112 0.021
Yeast
anatomical structure homeostasis GO:0060249 97 0.021
single organism catabolic process GO:0044712 228 0.021
Yeast
positive regulation of protein metabolic process GO:0051247 128 0.020
immune response GO:0006955 246 0.020
regulation of catalytic activity GO:0050790 185 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
Yeast
response to ionizing radiation GO:0010212 32 0.020
positive regulation of developmental process GO:0051094 143 0.020
regulation of response to dna damage stimulus GO:2001020 23 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
Yeast
purine ribonucleoside metabolic process GO:0046128 127 0.020
Yeast
intracellular transport GO:0046907 228 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
Yeast
aging GO:0007568 143 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
intracellular signal transduction GO:0035556 300 0.019
connective tissue development GO:0061448 3 0.019
growth GO:0040007 359 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
Yeast
single organism cellular localization GO:1902580 180 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.018
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
Yeast
protein complex assembly GO:0006461 200 0.018
female meiosis chromosome segregation GO:0016321 33 0.018
eye development GO:0001654 323 0.018
negative regulation of biosynthetic process GO:0009890 277 0.017
Yeast
dna biosynthetic process GO:0071897 24 0.017
purine ribonucleotide catabolic process GO:0009154 109 0.017
Yeast
purine ribonucleotide metabolic process GO:0009150 145 0.017
Yeast
regulation of nervous system development GO:0051960 248 0.017
meiotic cell cycle process GO:1903046 132 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.017
cell migration GO:0016477 238 0.017
protein depolymerization GO:0051261 31 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
compound eye development GO:0048749 307 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
Yeast
cytoplasmic transport GO:0016482 130 0.016
protein maturation GO:0051604 71 0.016
regulation of neurogenesis GO:0050767 158 0.016
nucleoside catabolic process GO:0009164 112 0.016
Yeast
macromolecular complex disassembly GO:0032984 37 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
Yeast
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
protein complex biogenesis GO:0070271 201 0.015
cellular protein localization GO:0034613 160 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
Yeast
appendage development GO:0048736 401 0.015
regulation of transport GO:0051049 181 0.015
sister chromatid cohesion GO:0007062 18 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
Yeast
developmental growth GO:0048589 280 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
Yeast
response to lipopolysaccharide GO:0032496 4 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
Yeast
positive regulation of phosphate metabolic process GO:0045937 139 0.014
regulation of gene silencing GO:0060968 63 0.014
regulation of localization GO:0032879 275 0.014
regulation of gtpase activity GO:0043087 44 0.014
organophosphate catabolic process GO:0046434 112 0.014
Yeast
cell motility GO:0048870 251 0.014
negative regulation of meiotic cell cycle GO:0051447 2 0.014
regulation of developmental growth GO:0048638 174 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.013
Yeast
regulation of endopeptidase activity GO:0052548 36 0.013
nucleotide metabolic process GO:0009117 161 0.013
Yeast
phagocytosis GO:0006909 215 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.013
Yeast
sister chromatid segregation GO:0000819 92 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
cellular macromolecular complex assembly GO:0034622 153 0.012
Yeast
positive regulation of signal transduction GO:0009967 223 0.012
regulation of immune system process GO:0002682 176 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
Yeast
single organism behavior GO:0044708 391 0.012
regulation of hydrolase activity GO:0051336 97 0.012
telomere organization GO:0032200 21 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
gtp catabolic process GO:0006184 72 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
Yeast
regulation of notch signaling pathway GO:0008593 100 0.012
response to organic substance GO:0010033 284 0.011
protein transport GO:0015031 155 0.011
negative regulation of cell death GO:0060548 81 0.011
reproductive structure development GO:0048608 74 0.011
Worm
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
negative regulation of microtubule depolymerization GO:0007026 21 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
Yeast
snrna metabolic process GO:0016073 14 0.011
meiotic chromosome separation GO:0051307 8 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
nucleoside metabolic process GO:0009116 127 0.011
Yeast
negative regulation of chromatin silencing GO:0031936 9 0.011
neurological system process GO:0050877 358 0.011
regulation of proteolysis GO:0030162 87 0.011
cellular amino acid metabolic process GO:0006520 61 0.010
defense response GO:0006952 300 0.010
regulation of cell projection organization GO:0031344 92 0.010
negative regulation of developmental process GO:0051093 201 0.010
covalent chromatin modification GO:0016569 106 0.010
negative regulation of cellular catabolic process GO:0031330 34 0.010
regulation of chromatin organization GO:1902275 32 0.010
proteolysis GO:0006508 192 0.010

Mcm3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.011