Drosophila melanogaster

32 known processes

Elongin-B (Dmel_CG4204)

Elongin B

(Aliases: CG4204,Dmel\CG4204)

Elongin-B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin assembly or disassembly GO:0006333 52 0.303
small molecule metabolic process GO:0044281 305 0.282
protein ubiquitination GO:0016567 70 0.255
chromosome organization GO:0051276 360 0.234
positive regulation of macromolecule metabolic process GO:0010604 405 0.184
Rat
ion transmembrane transport GO:0034220 122 0.183
imaginal disc derived appendage morphogenesis GO:0035114 395 0.149
protein catabolic process GO:0030163 101 0.113
single organism intracellular transport GO:1902582 207 0.108
positive regulation of response to stimulus GO:0048584 323 0.105
g2 dna damage checkpoint GO:0031572 69 0.103
protein modification by small protein conjugation or removal GO:0070647 106 0.101
intracellular signal transduction GO:0035556 300 0.095
epithelial cell differentiation GO:0030855 322 0.093
cation transmembrane transport GO:0098655 88 0.092
segmentation GO:0035282 207 0.088
ubiquitin dependent protein catabolic process GO:0006511 78 0.087
regulation of intracellular signal transduction GO:1902531 236 0.084
positive regulation of cellular biosynthetic process GO:0031328 316 0.084
Rat
growth GO:0040007 359 0.084
organonitrogen compound metabolic process GO:1901564 318 0.080
appendage morphogenesis GO:0035107 397 0.079
nucleotide metabolic process GO:0009117 161 0.077
oxoacid metabolic process GO:0043436 103 0.071
cellular catabolic process GO:0044248 372 0.070
enzyme linked receptor protein signaling pathway GO:0007167 179 0.068
regionalization GO:0003002 416 0.067
chromatin organization GO:0006325 207 0.065
transmembrane transport GO:0055085 139 0.065
regulation of anatomical structure morphogenesis GO:0022603 242 0.062
regulation of phosphate metabolic process GO:0019220 210 0.062
protein modification by small protein conjugation GO:0032446 79 0.061
cellular protein modification process GO:0006464 438 0.060
regulation of multicellular organismal development GO:2000026 414 0.059
organic acid metabolic process GO:0006082 103 0.059
protein dna complex subunit organization GO:0071824 86 0.059
positive regulation of protein metabolic process GO:0051247 128 0.058
negative regulation of developmental process GO:0051093 201 0.057
phosphorylation GO:0016310 294 0.055
dna conformation change GO:0071103 105 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.052
nucleoside phosphate metabolic process GO:0006753 162 0.050
mitotic g2 m transition checkpoint GO:0044818 70 0.050
cation transport GO:0006812 110 0.050
catabolic process GO:0009056 409 0.049
negative regulation of response to stimulus GO:0048585 258 0.048
oocyte development GO:0048599 124 0.048
epithelial cell development GO:0002064 274 0.048
oocyte differentiation GO:0009994 145 0.047
nucleoside metabolic process GO:0009116 127 0.045
purine ribonucleotide metabolic process GO:0009150 145 0.045
response to external biotic stimulus GO:0043207 293 0.044
positive regulation of signaling GO:0023056 243 0.044
embryonic pattern specification GO:0009880 174 0.044
regulation of phosphorus metabolic process GO:0051174 210 0.043
positive regulation of phosphate metabolic process GO:0045937 139 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.042
Rat
nucleoside phosphate catabolic process GO:1901292 110 0.042
organic substance transport GO:0071702 257 0.042
negative regulation of gene expression GO:0010629 387 0.042
oocyte construction GO:0007308 112 0.041
aggressive behavior GO:0002118 63 0.041
mitotic cell cycle phase transition GO:0044772 138 0.041
negative regulation of signaling GO:0023057 219 0.041
carbohydrate derivative metabolic process GO:1901135 217 0.041
positive regulation of rna biosynthetic process GO:1902680 266 0.040
Rat
positive regulation of transcription dna templated GO:0045893 266 0.040
Rat
organic substance catabolic process GO:1901575 308 0.040
regulation of protein metabolic process GO:0051246 256 0.039
developmental maturation GO:0021700 172 0.039
positive regulation of cellular protein metabolic process GO:0032270 118 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.039
Rat
regulation of cell differentiation GO:0045595 302 0.039
protein modification process GO:0036211 438 0.039
mitotic dna damage checkpoint GO:0044773 74 0.038
locomotory behavior GO:0007626 176 0.038
nucleoside triphosphate metabolic process GO:0009141 120 0.038
negative regulation of cell differentiation GO:0045596 143 0.037
mitotic dna integrity checkpoint GO:0044774 75 0.037
signal transduction by phosphorylation GO:0023014 107 0.037
proteolysis GO:0006508 192 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.035
axon guidance GO:0007411 233 0.035
regulation of cell cycle GO:0051726 291 0.035
regulation of immune system process GO:0002682 176 0.035
cellular protein catabolic process GO:0044257 83 0.034
regulation of cellular component biogenesis GO:0044087 201 0.034
macromolecular complex assembly GO:0065003 256 0.034
dna packaging GO:0006323 91 0.034
axis specification GO:0009798 167 0.033
protein complex assembly GO:0006461 200 0.033
lipid metabolic process GO:0006629 121 0.032
dna metabolic process GO:0006259 227 0.032
columnar cuboidal epithelial cell development GO:0002066 249 0.032
cell cycle phase transition GO:0044770 140 0.032
stem cell differentiation GO:0048863 117 0.031
organophosphate metabolic process GO:0019637 195 0.031
macromolecule catabolic process GO:0009057 161 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.031
organic cyclic compound catabolic process GO:1901361 168 0.031
positive regulation of biosynthetic process GO:0009891 316 0.030
Rat
post embryonic appendage morphogenesis GO:0035120 385 0.030
body morphogenesis GO:0010171 2 0.030
ribonucleotide metabolic process GO:0009259 145 0.030
purine nucleotide metabolic process GO:0006163 146 0.030
single organism biosynthetic process GO:0044711 206 0.030
carboxylic acid metabolic process GO:0019752 92 0.029
heterocycle catabolic process GO:0046700 166 0.029
oocyte axis specification GO:0007309 108 0.029
protein complex biogenesis GO:0070271 201 0.029
defense response GO:0006952 300 0.029
ribose phosphate metabolic process GO:0019693 145 0.029
ion transport GO:0006811 145 0.029
cellular macromolecule catabolic process GO:0044265 136 0.029
immune system process GO:0002376 347 0.029
regulation of catabolic process GO:0009894 170 0.029
cellular amine metabolic process GO:0044106 12 0.029
ribonucleoside metabolic process GO:0009119 127 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
modification dependent macromolecule catabolic process GO:0043632 79 0.028
response to other organism GO:0051707 293 0.028
dorsal ventral pattern formation GO:0009953 133 0.028
cell cell signaling involved in cell fate commitment GO:0045168 210 0.028
modification dependent protein catabolic process GO:0019941 78 0.028
regulation of cellular catabolic process GO:0031329 157 0.028
negative regulation of cell communication GO:0010648 223 0.028
nucleosome organization GO:0034728 59 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
Rat
response to organic substance GO:0010033 284 0.027
rna processing GO:0006396 147 0.027
embryonic axis specification GO:0000578 107 0.027
ribose phosphate biosynthetic process GO:0046390 28 0.027
chromatin assembly GO:0031497 48 0.027
negative regulation of signal transduction GO:0009968 206 0.026
positive regulation of signal transduction GO:0009967 223 0.026
purine nucleoside biosynthetic process GO:0042451 3 0.026
homeostatic process GO:0042592 199 0.026
inorganic ion transmembrane transport GO:0098660 73 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
regulation of molecular function GO:0065009 217 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.026
Rat
establishment of localization in cell GO:0051649 402 0.025
neurological system process GO:0050877 358 0.025
nucleotide catabolic process GO:0009166 109 0.025
regulation of response to stress GO:0080134 200 0.025
response to abiotic stimulus GO:0009628 341 0.025
mitotic g2 dna damage checkpoint GO:0007095 69 0.025
positive regulation of nucleic acid templated transcription GO:1903508 266 0.024
Rat
positive regulation of catabolic process GO:0009896 105 0.024
cellular ketone metabolic process GO:0042180 24 0.024
regulation of mitotic cell cycle phase transition GO:1901990 130 0.024
regulation of growth GO:0040008 233 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
photoreceptor cell differentiation GO:0046530 170 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
endocytosis GO:0006897 310 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
axonogenesis GO:0007409 290 0.023
purine nucleoside catabolic process GO:0006152 112 0.023
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.023
amine metabolic process GO:0009308 12 0.023
blastoderm segmentation GO:0007350 159 0.023
negative regulation of apoptotic process GO:0043066 63 0.023
ovarian follicle cell development GO:0030707 248 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
regulation of cell cycle phase transition GO:1901987 130 0.022
wing disc morphogenesis GO:0007472 344 0.022
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
gland development GO:0048732 191 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
response to alcohol GO:0097305 95 0.021
positive regulation of rna metabolic process GO:0051254 271 0.021
Rat
response to bacterium GO:0009617 198 0.021
taxis GO:0042330 304 0.021
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
anterior posterior axis specification GO:0009948 109 0.020
positive regulation of cellular protein catabolic process GO:1903364 24 0.020
negative regulation of cell development GO:0010721 62 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.020
single organism behavior GO:0044708 391 0.020
stem cell development GO:0048864 79 0.020
negative regulation of autophagy GO:0010507 16 0.020
cell maturation GO:0048469 144 0.020
cellular macromolecule localization GO:0070727 220 0.020
anterior posterior pattern specification GO:0009952 136 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
chemotaxis GO:0006935 249 0.020
regulation of localization GO:0032879 275 0.019
vesicle mediated transport GO:0016192 381 0.019
ribonucleoside biosynthetic process GO:0042455 3 0.019
purine containing compound metabolic process GO:0072521 155 0.019
head development GO:0060322 135 0.019
response to biotic stimulus GO:0009607 294 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
regulation of catalytic activity GO:0050790 185 0.019
imaginal disc derived wing vein specification GO:0007474 48 0.019
negative regulation of cell death GO:0060548 81 0.018
cation homeostasis GO:0055080 51 0.018
eye photoreceptor cell differentiation GO:0001754 145 0.018
positive regulation of protein catabolic process GO:0045732 34 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.018
response to radiation GO:0009314 155 0.018
stem cell maintenance GO:0019827 67 0.018
spindle organization GO:0007051 253 0.018
mapk cascade GO:0000165 107 0.018
cardiovascular system development GO:0072358 82 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
protein targeting GO:0006605 64 0.018
lateral inhibition GO:0046331 206 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
response to light stimulus GO:0009416 124 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
synapse organization GO:0050808 196 0.017
regulation of protein catabolic process GO:0042176 55 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
regulation of neurogenesis GO:0050767 158 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
regulation of dna metabolic process GO:0051052 34 0.017
single organism cellular localization GO:1902580 180 0.017
regulation of nervous system development GO:0051960 248 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
protein maturation GO:0051604 71 0.017
phagocytosis GO:0006909 215 0.017
cellular protein complex assembly GO:0043623 71 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
negative regulation of cell cycle GO:0045786 116 0.016
organophosphate catabolic process GO:0046434 112 0.016
purine ribonucleoside biosynthetic process GO:0046129 3 0.016
programmed cell death GO:0012501 257 0.016
chromatin remodeling GO:0006338 72 0.016
negative regulation of cell cycle process GO:0010948 109 0.016
establishment of protein localization GO:0045184 163 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.016
synapse assembly GO:0007416 143 0.016
positive regulation of nucleotide metabolic process GO:0045981 55 0.016
regulation of proteolysis GO:0030162 87 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
ion homeostasis GO:0050801 55 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.015
purine containing compound catabolic process GO:0072523 112 0.015
positive regulation of cell communication GO:0010647 250 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.015
protein transport GO:0015031 155 0.015
aromatic compound catabolic process GO:0019439 166 0.015
tripartite regional subdivision GO:0007351 103 0.015
eye development GO:0001654 323 0.015
appendage development GO:0048736 401 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
Rat
ras protein signal transduction GO:0007265 88 0.015
negative regulation of growth GO:0045926 84 0.015
regulation of cellular response to stress GO:0080135 89 0.014
rrna processing GO:0006364 3 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
gtp catabolic process GO:0006184 72 0.014
glycosyl compound biosynthetic process GO:1901659 3 0.014
axon development GO:0061564 297 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
Rat
sensory perception GO:0007600 196 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
positive regulation of developmental process GO:0051094 143 0.014
regulation of protein modification process GO:0031399 112 0.014
cellular response to organic substance GO:0071310 132 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
dorsal ventral axis specification GO:0009950 66 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.014
positive regulation of lipid metabolic process GO:0045834 4 0.014
organophosphate biosynthetic process GO:0090407 46 0.014
cell division GO:0051301 248 0.013
heart development GO:0007507 82 0.013
cellular cation homeostasis GO:0030003 38 0.013
protein k48 linked ubiquitination GO:0070936 3 0.013
regulation of developmental growth GO:0048638 174 0.013
transition metal ion homeostasis GO:0055076 17 0.013
single organism catabolic process GO:0044712 228 0.013
intracellular transport GO:0046907 228 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
mitotic spindle elongation GO:0000022 81 0.013
regulation of response to external stimulus GO:0032101 115 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
nucleoside catabolic process GO:0009164 112 0.013
ribonucleotide catabolic process GO:0009261 109 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
regulation of phosphorylation GO:0042325 147 0.012
intracellular protein transport GO:0006886 104 0.012
regulation of apoptotic process GO:0042981 130 0.012
regulation of mapk cascade GO:0043408 92 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
developmental growth GO:0048589 280 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
response to lipopolysaccharide GO:0032496 4 0.012
positive regulation of molecular function GO:0044093 136 0.012
circulatory system development GO:0072359 82 0.012
defense response to other organism GO:0098542 225 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.012
mitotic spindle organization GO:0007052 220 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
compound eye development GO:0048749 307 0.011
cell proliferation GO:0008283 299 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
protein dna complex assembly GO:0065004 63 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.011
regulation of synapse organization GO:0050807 110 0.011
cell death GO:0008219 279 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
nitrogen compound transport GO:0071705 85 0.011
immune response GO:0006955 246 0.011
cellular ion homeostasis GO:0006873 39 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
regulation of neuron differentiation GO:0045664 103 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.010
regulation of hydrolase activity GO:0051336 97 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.010
lipid localization GO:0010876 54 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
rna localization GO:0006403 115 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
dna integrity checkpoint GO:0031570 81 0.010
compound eye photoreceptor development GO:0042051 78 0.010
forebrain development GO:0030900 2 0.010
erk1 and erk2 cascade GO:0070371 39 0.010
protein phosphorylation GO:0006468 169 0.010

Elongin-B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017