Drosophila melanogaster

5 known processes

Tif-IA (Dmel_CG3278)

CG3278 gene product from transcript CG3278-RA

(Aliases: TifIA,CG3278,dTIF-IA,Dmel\CG3278,TIF-1A,Tif-1A,TIF-IA,CG16938,CG5951)

Tif-IA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell differentiation GO:0045595 302 0.749
positive regulation of biosynthetic process GO:0009891 316 0.490
Mouse
protein localization GO:0008104 284 0.473
cellular macromolecule localization GO:0070727 220 0.424
single organism cellular localization GO:1902580 180 0.402
cardiovascular system development GO:0072358 82 0.372
establishment of localization in cell GO:0051649 402 0.273
protein transport GO:0015031 155 0.258
protein complex biogenesis GO:0070271 201 0.239
Mouse
nuclear transport GO:0051169 72 0.216
positive regulation of rna biosynthetic process GO:1902680 266 0.198
Mouse
protein targeting GO:0006605 64 0.181
positive regulation of macromolecule metabolic process GO:0010604 405 0.179
Mouse
establishment of protein localization GO:0045184 163 0.156
intracellular transport GO:0046907 228 0.152
positive regulation of rna metabolic process GO:0051254 271 0.140
Mouse
cellular protein localization GO:0034613 160 0.137
single organism intracellular transport GO:1902582 207 0.132
positive regulation of cellular protein metabolic process GO:0032270 118 0.121
organic substance transport GO:0071702 257 0.118
eye development GO:0001654 323 0.113
cytoplasmic transport GO:0016482 130 0.111
cytoplasm organization GO:0007028 64 0.108
Mouse
muscle cell differentiation GO:0042692 103 0.106
positive regulation of nucleic acid templated transcription GO:1903508 266 0.106
Mouse
eye morphogenesis GO:0048592 260 0.089
cellular protein complex assembly GO:0043623 71 0.085
compound eye morphogenesis GO:0001745 249 0.080
nuclear export GO:0051168 24 0.079
multicellular organism growth GO:0035264 46 0.073
macromolecular complex assembly GO:0065003 256 0.073
Mouse
nucleocytoplasmic transport GO:0006913 72 0.067
larval development GO:0002164 104 0.066
single organism membrane organization GO:0044802 93 0.065
protein complex assembly GO:0006461 200 0.061
Mouse
establishment of protein localization to organelle GO:0072594 62 0.061
cell death GO:0008219 279 0.059
Mouse
hemopoiesis GO:0030097 46 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
Mouse
death GO:0016265 284 0.055
Mouse
programmed cell death GO:0012501 257 0.055
Mouse
mitochondrion organization GO:0007005 65 0.054
positive regulation of cellular biosynthetic process GO:0031328 316 0.052
Mouse
protein localization to organelle GO:0033365 82 0.052
developmental growth GO:0048589 280 0.052
apoptotic process GO:0006915 159 0.050
Mouse
gland development GO:0048732 191 0.050
regulation of multicellular organismal development GO:2000026 414 0.049
translation GO:0006412 69 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.047
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.046
Mouse
regulation of cell proliferation GO:0042127 163 0.046
regulation of nervous system development GO:0051960 248 0.043
regulation of programmed cell death GO:0043067 152 0.043
Mouse
regulation of apoptotic process GO:0042981 130 0.042
Mouse
stem cell maintenance GO:0019827 67 0.042
embryo development ending in birth or egg hatching GO:0009792 152 0.040
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.038
hematopoietic or lymphoid organ development GO:0048534 57 0.037
phagocytosis GO:0006909 215 0.036
exocrine system development GO:0035272 162 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.034
compound eye development GO:0048749 307 0.034
immune system process GO:0002376 347 0.033
regulation of localization GO:0032879 275 0.033
vesicle mediated transport GO:0016192 381 0.033
gland morphogenesis GO:0022612 145 0.033
rrna processing GO:0006364 3 0.032
sensory organ morphogenesis GO:0090596 260 0.031
positive regulation of gene expression GO:0010628 290 0.029
Mouse
morphogenesis of an epithelium GO:0002009 276 0.029
nuclear import GO:0051170 51 0.029
cellular component disassembly GO:0022411 46 0.028
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.028
Mouse
stem cell division GO:0017145 69 0.028
membrane organization GO:0061024 112 0.027
stem cell development GO:0048864 79 0.027
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.027
Mouse
ribonucleoprotein complex disassembly GO:0032988 1 0.026
protein modification process GO:0036211 438 0.026
cellular macromolecular complex assembly GO:0034622 153 0.026
g2 dna damage checkpoint GO:0031572 69 0.024
regulation of meiosis GO:0040020 3 0.024
positive regulation of cell growth GO:0030307 19 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
reproductive behavior GO:0019098 122 0.023
growth GO:0040007 359 0.023
regulation of immune system process GO:0002682 176 0.023
chromatin modification GO:0016568 147 0.023
proteolysis GO:0006508 192 0.022
ribonucleoprotein complex biogenesis GO:0022613 31 0.022
regulation of growth GO:0040008 233 0.021
body morphogenesis GO:0010171 2 0.021
positive regulation of translation GO:0045727 12 0.021
salivary gland morphogenesis GO:0007435 145 0.021
asymmetric stem cell division GO:0098722 49 0.021
positive regulation of developmental growth GO:0048639 62 0.021
multicellular organismal aging GO:0010259 140 0.020
rna processing GO:0006396 147 0.020
actin filament organization GO:0007015 126 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
intracellular protein transport GO:0006886 104 0.020
protein ubiquitination GO:0016567 70 0.019
regulation of organelle organization GO:0033043 196 0.019
regulation of protein metabolic process GO:0051246 256 0.019
neural retina development GO:0003407 4 0.018
regulation of hemocyte proliferation GO:0035206 37 0.018
circulatory system development GO:0072359 82 0.017
single organism nuclear import GO:1902593 51 0.017
regulation of oocyte development GO:0060281 27 0.017
cellular protein modification process GO:0006464 438 0.016
rna catabolic process GO:0006401 37 0.016
gene silencing by mirna GO:0035195 22 0.016
intermediate filament based process GO:0045103 1 0.016
response to external biotic stimulus GO:0043207 293 0.016
salivary gland development GO:0007431 162 0.015
salivary gland histolysis GO:0035070 88 0.015
regulation of developmental growth GO:0048638 174 0.015
negative regulation of gene expression GO:0010629 387 0.015
cellular amine metabolic process GO:0044106 12 0.014
negative regulation of developmental process GO:0051093 201 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
protein import GO:0017038 55 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
regulation of cell cycle process GO:0010564 181 0.014
regulation of translation GO:0006417 56 0.013
translational termination GO:0006415 2 0.013
intermediate filament cytoskeleton organization GO:0045104 1 0.013
nuclear division GO:0000280 332 0.013
immune system development GO:0002520 57 0.013
mrna metabolic process GO:0016071 124 0.013
negative regulation of phosphatase activity GO:0010923 3 0.013
regulation of histone methylation GO:0031060 10 0.012
protein export from nucleus GO:0006611 10 0.012
cellular catabolic process GO:0044248 372 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
homeostatic process GO:0042592 199 0.011
Mouse
mrna polyadenylation GO:0006378 11 0.011
establishment of organelle localization GO:0051656 122 0.011
locomotory behavior GO:0007626 176 0.011
protein targeting to nucleus GO:0044744 51 0.011
macromolecule catabolic process GO:0009057 161 0.011
regulation of protein modification process GO:0031399 112 0.011
phosphorylation GO:0016310 294 0.011
negative regulation of growth GO:0045926 84 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
organelle localization GO:0051640 148 0.011
regulation of signal transduction by p53 class mediator GO:1901796 1 0.010
Mouse
multi organism reproductive behavior GO:0044705 121 0.010
pole plasm oskar mrna localization GO:0045451 46 0.010
positive regulation of molecular function GO:0044093 136 0.010
positive regulation of viral process GO:0048524 2 0.010

Tif-IA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.023
osteogenesis imperfecta DOID:12347 0 0.023
bone development disease DOID:0080006 0 0.023
bone disease DOID:0080001 0 0.023
disease of anatomical entity DOID:7 0 0.023
musculoskeletal system disease DOID:17 0 0.023
connective tissue disease DOID:65 0 0.023
syndrome DOID:225 0 0.013
benign neoplasm DOID:0060072 0 0.010
disease of cellular proliferation DOID:14566 0 0.010