Drosophila melanogaster

12 known processes

ppl (Dmel_CG7758)

pumpless

(Aliases: CG7758,l(3)78Cb,Dmel\CG7758,l(3)00217)

ppl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
innate immune response GO:0045087 144 0.174
immune response GO:0006955 246 0.166
larval feeding behavior GO:0030536 15 0.116
detection of stimulus GO:0051606 156 0.098
response to bacterium GO:0009617 198 0.084
immune system process GO:0002376 347 0.076
programmed cell death GO:0012501 257 0.069
exocrine system development GO:0035272 162 0.069
g protein coupled receptor signaling pathway GO:0007186 136 0.065
defense response GO:0006952 300 0.060
feeding behavior GO:0007631 50 0.060
negative regulation of nucleic acid templated transcription GO:1903507 240 0.055
histolysis GO:0007559 102 0.055
single organism biosynthetic process GO:0044711 206 0.055
death GO:0016265 284 0.055
lipid localization GO:0010876 54 0.053
negative regulation of transcription dna templated GO:0045892 237 0.053
pigment biosynthetic process GO:0046148 36 0.052
organonitrogen compound biosynthetic process GO:1901566 117 0.051
developmental programmed cell death GO:0010623 138 0.050
regulation of immune system process GO:0002682 176 0.049
cell death GO:0008219 279 0.048
response to temperature stimulus GO:0009266 106 0.047
cellular amino acid metabolic process GO:0006520 61 0.047
oxoacid metabolic process GO:0043436 103 0.046
phosphatidylethanolamine metabolic process GO:0046337 1 0.045
gland development GO:0048732 191 0.043
response to external biotic stimulus GO:0043207 293 0.042
phototransduction GO:0007602 52 0.042
organophosphate metabolic process GO:0019637 195 0.041
small molecule metabolic process GO:0044281 305 0.040
carboxylic acid metabolic process GO:0019752 92 0.040
larval behavior GO:0030537 42 0.040
organophosphate biosynthetic process GO:0090407 46 0.038
positive regulation of rna biosynthetic process GO:1902680 266 0.037
organic acid metabolic process GO:0006082 103 0.036
response to extracellular stimulus GO:0009991 116 0.036
aromatic amino acid family metabolic process GO:0009072 3 0.036
response to nutrient levels GO:0031667 114 0.036
positive regulation of response to stimulus GO:0048584 323 0.035
tissue death GO:0016271 102 0.034
pigment metabolic process GO:0042440 84 0.034
response to other organism GO:0051707 293 0.034
nucleotide metabolic process GO:0009117 161 0.034
maintenance of location GO:0051235 73 0.034
gland morphogenesis GO:0022612 145 0.033
single organism behavior GO:0044708 391 0.032
neuropeptide signaling pathway GO:0007218 45 0.031
purine containing compound biosynthetic process GO:0072522 30 0.031
negative regulation of biosynthetic process GO:0009890 277 0.030
catabolic process GO:0009056 409 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
germarium derived egg chamber formation GO:0007293 101 0.030
endocytosis GO:0006897 310 0.029
response to abiotic stimulus GO:0009628 341 0.029
regulation of defense response GO:0031347 102 0.029
regulation of cell death GO:0010941 173 0.029
defense response to other organism GO:0098542 225 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
positive regulation of lipid metabolic process GO:0045834 4 0.028
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.027
organonitrogen compound metabolic process GO:1901564 318 0.027
sterol homeostasis GO:0055092 4 0.026
oxidation reduction process GO:0055114 123 0.026
vesicle mediated transport GO:0016192 381 0.026
positive regulation of signal transduction GO:0009967 223 0.026
detection of abiotic stimulus GO:0009582 66 0.026
small molecule biosynthetic process GO:0044283 37 0.025
hemolymph coagulation GO:0042381 10 0.025
autophagic cell death GO:0048102 83 0.025
lateral inhibition GO:0046331 206 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
neutral lipid catabolic process GO:0046461 3 0.024
homeostatic process GO:0042592 199 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.024
cellular amine metabolic process GO:0044106 12 0.024
male courtship behavior GO:0008049 63 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
regulation of catabolic process GO:0009894 170 0.023
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
alditol phosphate metabolic process GO:0052646 2 0.023
apoptotic process GO:0006915 159 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
salivary gland histolysis GO:0035070 88 0.023
salivary gland cell autophagic cell death GO:0035071 83 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
regulation of behavior GO:0050795 75 0.022
organelle fusion GO:0048284 46 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
eye pigment biosynthetic process GO:0006726 32 0.022
phagocytosis GO:0006909 215 0.022
positive regulation of signaling GO:0023056 243 0.021
salivary gland development GO:0007431 162 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
acylglycerol catabolic process GO:0046464 3 0.021
positive regulation of rna metabolic process GO:0051254 271 0.021
intracellular signal transduction GO:0035556 300 0.021
response to biotic stimulus GO:0009607 294 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
locomotory behavior GO:0007626 176 0.020
organic substance catabolic process GO:1901575 308 0.020
purine nucleotide biosynthetic process GO:0006164 29 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
rhythmic process GO:0048511 106 0.020
indole containing compound biosynthetic process GO:0042435 4 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
oocyte differentiation GO:0009994 145 0.019
nucleoside phosphate biosynthetic process GO:1901293 34 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
oligosaccharide metabolic process GO:0009311 18 0.019
lipid storage GO:0019915 38 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
heterocycle catabolic process GO:0046700 166 0.018
positive regulation of behavior GO:0048520 19 0.018
ribose phosphate biosynthetic process GO:0046390 28 0.018
hindbrain development GO:0030902 2 0.018
intracellular protein transmembrane import GO:0044743 4 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
cellular protein modification process GO:0006464 438 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
dopamine biosynthetic process GO:0042416 3 0.018
detection of external stimulus GO:0009581 66 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
neuromuscular junction development GO:0007528 149 0.017
cellular catabolic process GO:0044248 372 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
wing disc morphogenesis GO:0007472 344 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
appendage development GO:0048736 401 0.017
regulation of catalytic activity GO:0050790 185 0.017
single organism membrane fusion GO:0044801 42 0.017
appendage morphogenesis GO:0035107 397 0.017
rhythmic behavior GO:0007622 76 0.017
body morphogenesis GO:0010171 2 0.017
response to oxygen containing compound GO:1901700 200 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
response to organic substance GO:0010033 284 0.016
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.016
protein localization GO:0008104 284 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
aromatic compound catabolic process GO:0019439 166 0.016
developmental pigmentation GO:0048066 68 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
segmentation GO:0035282 207 0.016
membrane organization GO:0061024 112 0.015
developmental maturation GO:0021700 172 0.015
nucleotide biosynthetic process GO:0009165 34 0.015
phospholipid homeostasis GO:0055091 1 0.015
vesicle fusion GO:0006906 19 0.015
primary amino compound biosynthetic process GO:1901162 2 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
regulation of programmed cell death GO:0043067 152 0.015
purine containing compound metabolic process GO:0072521 155 0.015
regulation of immune response GO:0050776 118 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.015
single organism membrane organization GO:0044802 93 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
lipid biosynthetic process GO:0008610 46 0.015
phosphatidylinositol mediated signaling GO:0048015 4 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
amine metabolic process GO:0009308 12 0.014
response to wounding GO:0009611 94 0.014
localization of cell GO:0051674 257 0.014
rna processing GO:0006396 147 0.014
positive regulation of developmental process GO:0051094 143 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of lipid storage GO:0010883 22 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
wound healing GO:0042060 75 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.014
head development GO:0060322 135 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.013
forebrain development GO:0030900 2 0.013
humoral immune response GO:0006959 117 0.013
pigmentation GO:0043473 75 0.013
positive regulation of cell communication GO:0010647 250 0.013
ethanolamine containing compound metabolic process GO:0042439 4 0.013
central nervous system development GO:0007417 201 0.013
protein complex disassembly GO:0043241 36 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
male gamete generation GO:0048232 201 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
pyridine nucleotide metabolic process GO:0019362 2 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
regulation of transport GO:0051049 181 0.013
ribonucleotide biosynthetic process GO:0009260 28 0.013
spindle assembly GO:0051225 80 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
cell maturation GO:0048469 144 0.013
oxidoreduction coenzyme metabolic process GO:0006733 2 0.013
thioester metabolic process GO:0035383 3 0.012
positive regulation of cell death GO:0010942 69 0.012
negative regulation of gene expression GO:0010629 387 0.012
single organism catabolic process GO:0044712 228 0.012
intracellular protein transmembrane transport GO:0065002 4 0.012
tripartite regional subdivision GO:0007351 103 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
acyl coa metabolic process GO:0006637 3 0.012
detection of chemical stimulus GO:0009593 93 0.012
purine ribonucleotide biosynthetic process GO:0009152 28 0.012
defense response to bacterium GO:0042742 178 0.012
cell division GO:0051301 248 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.012
cell projection assembly GO:0030031 94 0.012
positive regulation of catabolic process GO:0009896 105 0.012
response to lipopolysaccharide GO:0032496 4 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
organic substance transport GO:0071702 257 0.011
malpighian tubule morphogenesis GO:0007443 44 0.011
regulation of localization GO:0032879 275 0.011
mitotic spindle organization GO:0007052 220 0.011
pigment metabolic process involved in pigmentation GO:0043474 33 0.011
renal system development GO:0072001 72 0.011
regulation of protein complex disassembly GO:0043244 29 0.011
protein localization to organelle GO:0033365 82 0.011
protein transport GO:0015031 155 0.011
anterior posterior axis specification GO:0009948 109 0.011
regulation of lipid catabolic process GO:0050994 3 0.011
mitotic nuclear division GO:0007067 213 0.011
neutral lipid biosynthetic process GO:0046460 2 0.011
protein modification process GO:0036211 438 0.011
axis specification GO:0009798 167 0.011
circadian rhythm GO:0007623 105 0.011
molting cycle chitin based cuticle GO:0007591 56 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
cholesterol transport GO:0030301 2 0.011
regulation of endocytosis GO:0030100 37 0.011
mesenchymal cell development GO:0014031 1 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
detection of light stimulus GO:0009583 58 0.011
spermatogenesis GO:0007283 200 0.011
regulation of innate immune response GO:0045088 71 0.011
mesenchymal cell differentiation GO:0048762 1 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
connective tissue development GO:0061448 3 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
glycerolipid catabolic process GO:0046503 3 0.010
catechol containing compound biosynthetic process GO:0009713 3 0.010
phosphatidylcholine metabolic process GO:0046470 3 0.010
protein complex biogenesis GO:0070271 201 0.010
cell proliferation GO:0008283 299 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
kidney development GO:0001822 3 0.010
regulation of apoptotic process GO:0042981 130 0.010

ppl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.011