Drosophila melanogaster

43 known processes

Leucokinin (Dmel_CG13480)

CG13480 gene product from transcript CG13480-RA

(Aliases: leukokinin,pp,DLK,leucokinin,Leuk,LK,Lk,Drm-KIN,Dmel\CG13480,CG13480)

Leucokinin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 136 0.073
neuropeptide signaling pathway GO:0007218 45 0.044
synaptic transmission GO:0007268 288 0.042
single organism behavior GO:0044708 391 0.040
positive regulation of cell communication GO:0010647 250 0.037
positive regulation of signaling GO:0023056 243 0.037
response to abiotic stimulus GO:0009628 341 0.035
neuron projection guidance GO:0097485 241 0.035
taxis GO:0042330 304 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.032
negative regulation of gene expression GO:0010629 387 0.032
regionalization GO:0003002 416 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
camera type eye development GO:0043010 4 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
response to oxygen containing compound GO:1901700 200 0.030
intracellular signal transduction GO:0035556 300 0.030
positive regulation of signal transduction GO:0009967 223 0.030
catabolic process GO:0009056 409 0.029
compound eye development GO:0048749 307 0.029
cellular catabolic process GO:0044248 372 0.029
response to radiation GO:0009314 155 0.029
organic substance catabolic process GO:1901575 308 0.028
axonogenesis GO:0007409 290 0.028
axon guidance GO:0007411 233 0.027
homeostatic process GO:0042592 199 0.027
chemotaxis GO:0006935 249 0.027
neurological system process GO:0050877 358 0.026
phagocytosis GO:0006909 215 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
small molecule metabolic process GO:0044281 305 0.025
telencephalon development GO:0021537 2 0.025
protein modification process GO:0036211 438 0.025
adult behavior GO:0030534 137 0.025
cellular response to ethanol GO:0071361 4 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
appendage development GO:0048736 401 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
response to biotic stimulus GO:0009607 294 0.024
forebrain development GO:0030900 2 0.024
regulation of molecular function GO:0065009 217 0.024
body morphogenesis GO:0010171 2 0.024
regulation of cell cycle GO:0051726 291 0.023
wing disc morphogenesis GO:0007472 344 0.023
axon development GO:0061564 297 0.023
eye development GO:0001654 323 0.023
response to other organism GO:0051707 293 0.023
response to organic substance GO:0010033 284 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
anatomical structure homeostasis GO:0060249 97 0.022
lateral inhibition GO:0046331 206 0.022
proteolysis GO:0006508 192 0.022
organelle fission GO:0048285 340 0.022
ion transport GO:0006811 145 0.022
mitotic nuclear division GO:0007067 213 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.022
death GO:0016265 284 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
endocytosis GO:0006897 310 0.022
sensory perception of chemical stimulus GO:0007606 116 0.022
response to light stimulus GO:0009416 124 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
sensory organ morphogenesis GO:0090596 260 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
compound eye morphogenesis GO:0001745 249 0.021
single organism catabolic process GO:0044712 228 0.021
negative regulation of developmental process GO:0051093 201 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
programmed cell death GO:0012501 257 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
negative regulation of signal transduction GO:0009968 206 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
immune system process GO:0002376 347 0.021
response to external biotic stimulus GO:0043207 293 0.021
kidney development GO:0001822 3 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
protein localization GO:0008104 284 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
cell death GO:0008219 279 0.020
aromatic compound catabolic process GO:0019439 166 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
eye morphogenesis GO:0048592 260 0.020
detection of stimulus GO:0051606 156 0.019
establishment of protein localization GO:0045184 163 0.019
appendage morphogenesis GO:0035107 397 0.019
behavioral response to ethanol GO:0048149 49 0.019
negative regulation of cell communication GO:0010648 223 0.019
response to alcohol GO:0097305 95 0.019
actin filament based process GO:0030029 220 0.019
response to lipopolysaccharide GO:0032496 4 0.019
vesicle mediated transport GO:0016192 381 0.019
apoptotic process GO:0006915 159 0.019
actin cytoskeleton organization GO:0030036 206 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
organic acid metabolic process GO:0006082 103 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
phosphorylation GO:0016310 294 0.019
heterocycle catabolic process GO:0046700 166 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.018
cellular protein modification process GO:0006464 438 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
immune response GO:0006955 246 0.018
exocrine system development GO:0035272 162 0.018
sensory perception of smell GO:0007608 80 0.018
neuromuscular synaptic transmission GO:0007274 67 0.018
nucleotide metabolic process GO:0009117 161 0.018
macromolecular complex assembly GO:0065003 256 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
regulation of nervous system development GO:0051960 248 0.018
salivary gland development GO:0007431 162 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
negative regulation of signaling GO:0023057 219 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
response to organophosphorus GO:0046683 2 0.017
xenobiotic catabolic process GO:0042178 1 0.017
oxoacid metabolic process GO:0043436 103 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
salivary gland morphogenesis GO:0007435 145 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
amine metabolic process GO:0009308 12 0.017
regulation of synaptic transmission GO:0050804 69 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
camera type eye morphogenesis GO:0048593 2 0.017
nuclear division GO:0000280 332 0.017
gland morphogenesis GO:0022612 145 0.017
regulation of protein metabolic process GO:0051246 256 0.017
multi organism behavior GO:0051705 175 0.017
regulation of anatomical structure size GO:0090066 163 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
hormone catabolic process GO:0042447 3 0.017
cell proliferation GO:0008283 299 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.017
developmental maturation GO:0021700 172 0.017
regulation of developmental growth GO:0048638 174 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
synapse organization GO:0050808 196 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
purine containing compound metabolic process GO:0072521 155 0.016
cellular ketone metabolic process GO:0042180 24 0.016
innate immune response GO:0045087 144 0.016
establishment of localization in cell GO:0051649 402 0.016
detection of light stimulus GO:0009583 58 0.016
retina development in camera type eye GO:0060041 4 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
retina morphogenesis in camera type eye GO:0060042 2 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
response to ethanol GO:0045471 59 0.015
cell division GO:0051301 248 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
defense response to other organism GO:0098542 225 0.015
single organism biosynthetic process GO:0044711 206 0.015
gland development GO:0048732 191 0.015
cell recognition GO:0008037 102 0.015
organophosphate metabolic process GO:0019637 195 0.015
segmentation GO:0035282 207 0.015
regulation of catabolic process GO:0009894 170 0.015
purine containing compound catabolic process GO:0072523 112 0.015
regulation of catalytic activity GO:0050790 185 0.015
connective tissue development GO:0061448 3 0.015
transmembrane transport GO:0055085 139 0.015
purine nucleoside metabolic process GO:0042278 127 0.014
neuron recognition GO:0008038 101 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
cellular amine metabolic process GO:0044106 12 0.014
actin filament organization GO:0007015 126 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
ras protein signal transduction GO:0007265 88 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
positive regulation of gene expression GO:0010628 290 0.014
axis specification GO:0009798 167 0.014
blastoderm segmentation GO:0007350 159 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
detection of chemical stimulus GO:0009593 93 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
regulation of organelle organization GO:0033043 196 0.014
growth GO:0040007 359 0.014
synaptic growth at neuromuscular junction GO:0051124 119 0.014
vitamin biosynthetic process GO:0009110 1 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
regulation of cell death GO:0010941 173 0.014
regulation of cell cycle process GO:0010564 181 0.014
immune response activating signal transduction GO:0002757 2 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
positive regulation of cell motility GO:2000147 3 0.014
protein maturation GO:0051604 71 0.014
protein transport GO:0015031 155 0.014
protein ubiquitination GO:0016567 70 0.014
protein complex assembly GO:0006461 200 0.014
fat soluble vitamin biosynthetic process GO:0042362 1 0.013
tube morphogenesis GO:0035239 191 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
organelle assembly GO:0070925 198 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
locomotory behavior GO:0007626 176 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
regulation of notch signaling pathway GO:0008593 100 0.013
androgen metabolic process GO:0008209 1 0.013
response to monosaccharide GO:0034284 4 0.013
regulation of programmed cell death GO:0043067 152 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
limb development GO:0060173 1 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
mapk cascade GO:0000165 107 0.013
developmental growth GO:0048589 280 0.013
positive regulation of cell migration GO:0030335 2 0.013
regulation of defense response GO:0031347 102 0.013
cellular homeostasis GO:0019725 80 0.013
response to bacterium GO:0009617 198 0.013
regulation of transport GO:0051049 181 0.013
regulation of multi organism process GO:0043900 131 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
innate immune response activating signal transduction GO:0002758 2 0.013
cation transport GO:0006812 110 0.013
cellular amide metabolic process GO:0043603 80 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
peptide metabolic process GO:0006518 80 0.013
chemosensory behavior GO:0007635 106 0.013
regulation of response to stress GO:0080134 200 0.013
positive regulation of developmental process GO:0051094 143 0.013
central nervous system development GO:0007417 201 0.013
vitamin metabolic process GO:0006766 2 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
regulation of growth GO:0040008 233 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
nucleoside catabolic process GO:0009164 112 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
epithelial cell differentiation GO:0030855 322 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
synapse assembly GO:0007416 143 0.012
protein processing GO:0016485 68 0.012
regulation of localization GO:0032879 275 0.012
metal ion homeostasis GO:0055065 44 0.012
regulation of cell proliferation GO:0042127 163 0.012
protein phosphorylation GO:0006468 169 0.012
cellular protein localization GO:0034613 160 0.012
embryonic pattern specification GO:0009880 174 0.012
activation of innate immune response GO:0002218 4 0.012
notch signaling pathway GO:0007219 120 0.012
intracellular transport GO:0046907 228 0.012
regulation of apoptotic process GO:0042981 130 0.012
regulation of response to external stimulus GO:0032101 115 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
cellular macromolecule localization GO:0070727 220 0.012
regulation of immune system process GO:0002682 176 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
membrane depolarization GO:0051899 4 0.012
defense response to bacterium GO:0042742 178 0.012
positive regulation of molecular function GO:0044093 136 0.012
rna processing GO:0006396 147 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
hindbrain development GO:0030902 2 0.012
leg disc development GO:0035218 92 0.012
respiratory system development GO:0060541 213 0.012
tube development GO:0035295 244 0.012
neuromuscular junction development GO:0007528 149 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
protein complex biogenesis GO:0070271 201 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
mrna metabolic process GO:0016071 124 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
regulation of cell development GO:0060284 215 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
developmental programmed cell death GO:0010623 138 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
organic substance transport GO:0071702 257 0.012
epithelial cell development GO:0002064 274 0.012
negative regulation of protein metabolic process GO:0051248 85 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
defense response GO:0006952 300 0.011
peptidyl proline modification GO:0018208 3 0.011
protein heterooligomerization GO:0051291 4 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
anterior posterior pattern specification GO:0009952 136 0.011
endomembrane system organization GO:0010256 119 0.011
digestive tract morphogenesis GO:0048546 127 0.011
kidney epithelium development GO:0072073 3 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
motor neuron axon guidance GO:0008045 58 0.011
cell motility GO:0048870 251 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
stem cell proliferation GO:0072089 88 0.011
regulation of hydrolase activity GO:0051336 97 0.011
nephron development GO:0072006 3 0.011
regulation of synapse organization GO:0050807 110 0.011
regulation of cell differentiation GO:0045595 302 0.011
digestive system development GO:0055123 149 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
response to glucose GO:0009749 2 0.011
regulation of proteolysis GO:0030162 87 0.011
spinal cord development GO:0021510 1 0.011
cell adhesion GO:0007155 136 0.011
olfactory behavior GO:0042048 97 0.011
single organism intracellular transport GO:1902582 207 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
single organism cellular localization GO:1902580 180 0.011
cellular response to organic substance GO:0071310 132 0.011
digestive tract development GO:0048565 149 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
nucleotide catabolic process GO:0009166 109 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.011
organophosphate catabolic process GO:0046434 112 0.011
biological adhesion GO:0022610 138 0.011
adult locomotory behavior GO:0008344 76 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
synaptic target recognition GO:0008039 45 0.011
regulation of ras protein signal transduction GO:0046578 93 0.010
sensory perception GO:0007600 196 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.010
embryonic morphogenesis GO:0048598 206 0.010
macromolecule catabolic process GO:0009057 161 0.010
regulation of gene silencing GO:0060968 63 0.010
gtp metabolic process GO:0046039 72 0.010
negative regulation of nervous system development GO:0051961 92 0.010
steroid catabolic process GO:0006706 1 0.010
nucleoside metabolic process GO:0009116 127 0.010
ovarian follicle cell development GO:0030707 248 0.010
positive regulation of proteolysis GO:0045862 52 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
regulation of immune response GO:0050776 118 0.010
regulation of synapse assembly GO:0051963 94 0.010
regulation of cellular component size GO:0032535 98 0.010
cell maturation GO:0048469 144 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
spindle organization GO:0007051 253 0.010
embryonic axis specification GO:0000578 107 0.010
monocarboxylic acid transport GO:0015718 3 0.010
mesenchymal cell development GO:0014031 1 0.010
localization of cell GO:0051674 257 0.010
estrogen metabolic process GO:0008210 1 0.010

Leucokinin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.034
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
musculoskeletal system disease DOID:17 0 0.015
disease of metabolism DOID:0014667 0 0.011
hypertension DOID:10763 0 0.010
artery disease DOID:0050828 0 0.010
vascular disease DOID:178 0 0.010
cardiovascular system disease DOID:1287 0 0.010