Drosophila melanogaster

47 known processes

Rev1 (Dmel_CG12189)

CG12189 gene product from transcript CG12189-RA

(Aliases: DmREV1,DmRev1,CG12189,Dmel\CG12189,AAF47401,dREV1,REV1,drev1)

Rev1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 54 0.937
double strand break repair GO:0006302 26 0.741
cellular response to dna damage stimulus GO:0006974 223 0.627
double strand break repair via nonhomologous end joining GO:0006303 5 0.622
dna metabolic process GO:0006259 227 0.457
dna damage checkpoint GO:0000077 78 0.432
negative regulation of cellular metabolic process GO:0031324 382 0.358
mitotic dna damage checkpoint GO:0044773 74 0.347
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.320
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.293
non recombinational repair GO:0000726 7 0.286
chromosome organization GO:0051276 360 0.276
negative regulation of cellular biosynthetic process GO:0031327 277 0.276
mitotic g2 dna damage checkpoint GO:0007095 69 0.275
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.271
negative regulation of cell cycle phase transition GO:1901988 103 0.218
dna duplex unwinding GO:0032508 16 0.172
nucleobase containing compound catabolic process GO:0034655 165 0.172
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.170
mitotic g2 m transition checkpoint GO:0044818 70 0.168
negative regulation of biosynthetic process GO:0009890 277 0.153
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.153
g2 dna damage checkpoint GO:0031572 69 0.129
dna geometric change GO:0032392 16 0.125
chromatin organization GO:0006325 207 0.124
cellular protein modification process GO:0006464 438 0.123
glycosyl compound metabolic process GO:1901657 127 0.119
nucleoside triphosphate catabolic process GO:0009143 108 0.117
regulation of cell cycle process GO:0010564 181 0.109
positive regulation of cellular biosynthetic process GO:0031328 316 0.105
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.101
regulation of mitotic cell cycle GO:0007346 190 0.100
protein modification process GO:0036211 438 0.100
multicellular organismal aging GO:0010259 140 0.093
organelle fission GO:0048285 340 0.092
negative regulation of rna biosynthetic process GO:1902679 240 0.090
organic substance catabolic process GO:1901575 308 0.084
negative regulation of rna metabolic process GO:0051253 251 0.084
cellular nitrogen compound catabolic process GO:0044270 165 0.082
cellular macromolecule catabolic process GO:0044265 136 0.081
chromatin modification GO:0016568 147 0.079
heterocycle catabolic process GO:0046700 166 0.076
organonitrogen compound metabolic process GO:1901564 318 0.076
negative regulation of developmental process GO:0051093 201 0.074
response to radiation GO:0009314 155 0.074
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.073
negative regulation of cell cycle GO:0045786 116 0.072
negative regulation of cell cycle process GO:0010948 109 0.068
aging GO:0007568 143 0.068
catabolic process GO:0009056 409 0.067
dna replication GO:0006260 48 0.065
regulation of mitotic cell cycle phase transition GO:1901990 130 0.065
cell motility GO:0048870 251 0.065
regulation of dna metabolic process GO:0051052 34 0.064
histone modification GO:0016570 106 0.063
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.061
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.061
negative regulation of gene expression GO:0010629 387 0.060
nucleotide excision repair GO:0006289 8 0.060
negative regulation of nucleic acid templated transcription GO:1903507 240 0.060
single organism biosynthetic process GO:0044711 206 0.057
Yeast Mouse
macromolecule catabolic process GO:0009057 161 0.057
positive regulation of rna biosynthetic process GO:1902680 266 0.056
embryo development ending in birth or egg hatching GO:0009792 152 0.055
Worm
purine ribonucleoside metabolic process GO:0046128 127 0.054
positive regulation of biosynthetic process GO:0009891 316 0.053
aromatic compound catabolic process GO:0019439 166 0.053
death GO:0016265 284 0.052
negative regulation of mitotic cell cycle GO:0045930 109 0.052
cellular catabolic process GO:0044248 372 0.050
epithelial cell development GO:0002064 274 0.049
nuclear division GO:0000280 332 0.049
positive regulation of transcription dna templated GO:0045893 266 0.049
mitotic recombination GO:0006312 2 0.048
telomere organization GO:0032200 21 0.048
anatomical structure homeostasis GO:0060249 97 0.048
ribonucleotide metabolic process GO:0009259 145 0.048
negative regulation of transcription dna templated GO:0045892 237 0.046
response to other organism GO:0051707 293 0.045
postreplication repair GO:0006301 2 0.045
Yeast Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.044
organic cyclic compound catabolic process GO:1901361 168 0.043
cell cycle checkpoint GO:0000075 95 0.043
dna double strand break processing GO:0000729 3 0.042
response to light stimulus GO:0009416 124 0.042
Human
regulation of cell cycle GO:0051726 291 0.042
macromolecular complex assembly GO:0065003 256 0.041
ribonucleoside metabolic process GO:0009119 127 0.040
appendage development GO:0048736 401 0.039
appendage morphogenesis GO:0035107 397 0.039
small molecule metabolic process GO:0044281 305 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
mitotic dna integrity checkpoint GO:0044774 75 0.038
dna synthesis involved in dna repair GO:0000731 5 0.038
cell death GO:0008219 279 0.038
positive regulation of gene expression GO:0010628 290 0.037
meiotic cell cycle process GO:1903046 132 0.037
dna biosynthetic process GO:0071897 24 0.035
Yeast Mouse
mitotic cell cycle phase transition GO:0044772 138 0.035
ribose phosphate metabolic process GO:0019693 145 0.034
dna amplification GO:0006277 11 0.034
ribonucleoside catabolic process GO:0042454 112 0.034
meiosis i GO:0007127 59 0.034
enzyme linked receptor protein signaling pathway GO:0007167 179 0.033
ovarian follicle cell development GO:0030707 248 0.033
chromosome segregation GO:0007059 157 0.032
protein catabolic process GO:0030163 101 0.032
cellular protein complex assembly GO:0043623 71 0.031
cell cycle phase transition GO:0044770 140 0.031
purine nucleoside triphosphate catabolic process GO:0009146 108 0.031
mitotic cell cycle checkpoint GO:0007093 88 0.031
recombinational repair GO:0000725 13 0.031
purine nucleotide catabolic process GO:0006195 109 0.030
organ growth GO:0035265 56 0.030
response to ionizing radiation GO:0010212 32 0.030
response to endogenous stimulus GO:0009719 119 0.030
regulation of apoptotic process GO:0042981 130 0.029
epithelium migration GO:0090132 148 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
purine nucleoside monophosphate metabolic process GO:0009126 50 0.029
purine containing compound catabolic process GO:0072523 112 0.029
localization of cell GO:0051674 257 0.029
cell aging GO:0007569 2 0.029
chromatin silencing GO:0006342 76 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
body morphogenesis GO:0010171 2 0.027
regulation of protein metabolic process GO:0051246 256 0.027
nucleotide catabolic process GO:0009166 109 0.027
positive regulation of signaling GO:0023056 243 0.027
purine nucleoside catabolic process GO:0006152 112 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.026
telomere maintenance GO:0000723 21 0.026
regulation of programmed cell death GO:0043067 152 0.026
regionalization GO:0003002 416 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
single organism catabolic process GO:0044712 228 0.025
proteolysis GO:0006508 192 0.025
regulation of response to stress GO:0080134 200 0.025
dna templated transcription elongation GO:0006354 18 0.024
nucleoside phosphate catabolic process GO:1901292 110 0.024
purine nucleoside monophosphate catabolic process GO:0009128 38 0.024
negative regulation of cell differentiation GO:0045596 143 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
protein maturation GO:0051604 71 0.023
response to organonitrogen compound GO:0010243 75 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
regulation of cell cycle phase transition GO:1901987 130 0.022
positive regulation of signal transduction GO:0009967 223 0.022
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
programmed cell death GO:0012501 257 0.022
double strand break repair via homologous recombination GO:0000724 13 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
chromatin assembly or disassembly GO:0006333 52 0.021
covalent chromatin modification GO:0016569 106 0.021
ribonucleoside monophosphate catabolic process GO:0009158 39 0.021
regulation of organelle organization GO:0033043 196 0.021
regulation of cellular response to stress GO:0080135 89 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
atp metabolic process GO:0046034 49 0.020
response to abiotic stimulus GO:0009628 341 0.020
Human
tissue migration GO:0090130 155 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
regulation of multicellular organismal development GO:2000026 414 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
response to nitrogen compound GO:1901698 90 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
reciprocal meiotic recombination GO:0007131 19 0.019
protein phosphorylation GO:0006468 169 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
epithelial cell migration GO:0010631 148 0.018
response to organic substance GO:0010033 284 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
regulation of molecular function GO:0065009 217 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
defense response GO:0006952 300 0.017
positive regulation of cell communication GO:0010647 250 0.017
organophosphate catabolic process GO:0046434 112 0.017
ribonucleoside monophosphate metabolic process GO:0009161 51 0.017
modification dependent macromolecule catabolic process GO:0043632 79 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
regulation of dna repair GO:0006282 5 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
cellular response to organic substance GO:0071310 132 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
mitotic nuclear division GO:0007067 213 0.016
ameboidal type cell migration GO:0001667 151 0.016
regulation of catalytic activity GO:0050790 185 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
negative regulation of apoptotic process GO:0043066 63 0.015
determination of adult lifespan GO:0008340 137 0.015
nucleoside catabolic process GO:0009164 112 0.015
nucleoside metabolic process GO:0009116 127 0.015
organophosphate metabolic process GO:0019637 195 0.015
nucleotide metabolic process GO:0009117 161 0.015
anterior posterior pattern specification GO:0009952 136 0.015
translesion synthesis GO:0019985 2 0.014
Yeast Mouse
positive regulation of catalytic activity GO:0043085 118 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
central nervous system development GO:0007417 201 0.014
regulation of protein modification process GO:0031399 112 0.014
mrna metabolic process GO:0016071 124 0.014
lipid storage GO:0019915 38 0.013
response to alkaloid GO:0043279 26 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
meiotic cell cycle GO:0051321 171 0.013
regulation of hydrolase activity GO:0051336 97 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
dna conformation change GO:0071103 105 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
cell proliferation GO:0008283 299 0.013
dna integrity checkpoint GO:0031570 81 0.013
immune system process GO:0002376 347 0.013
regulation of dna recombination GO:0000018 4 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.013
regulation of localization GO:0032879 275 0.013
protein complex assembly GO:0006461 200 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.012
telomere maintenance via recombination GO:0000722 1 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
regulation of protein catabolic process GO:0042176 55 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
amine metabolic process GO:0009308 12 0.012
regulation of nervous system development GO:0051960 248 0.012
developmental programmed cell death GO:0010623 138 0.012
karyosome formation GO:0030717 22 0.012
positive regulation of developmental process GO:0051094 143 0.011
peptidyl amino acid modification GO:0018193 105 0.011
positive regulation of molecular function GO:0044093 136 0.011
reproductive behavior GO:0019098 122 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
regulation of meiosis GO:0040020 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
protein processing GO:0016485 68 0.011
intracellular signal transduction GO:0035556 300 0.011
regulation of response to dna damage stimulus GO:2001020 23 0.011
negative regulation of signal transduction GO:0009968 206 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
axis specification GO:0009798 167 0.010
mrna processing GO:0006397 104 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.010
purine containing compound metabolic process GO:0072521 155 0.010
negative regulation of cell death GO:0060548 81 0.010

Rev1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.044
disease of cellular proliferation DOID:14566 0 0.044
organ system cancer DOID:0050686 0 0.032
disease of anatomical entity DOID:7 0 0.014