Drosophila melanogaster

147 known processes

cact (Dmel_CG5848)

cactus

(Aliases: CACT,Dmel\CG5848,Cact,BG:DS02740.15,n(2)k17003,CG5848,fs(2)ltoRN48,cac,dip6,5848)

cact biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of antifungal peptide production GO:0002804 6 0.999
regulation of antifungal peptide production GO:0002788 6 0.994
antifungal humoral response GO:0019732 12 0.985
axis specification GO:0009798 167 0.969
regulation of defense response to fungus GO:1900150 6 0.965
oocyte development GO:0048599 124 0.955
defense response to fungus GO:0050832 48 0.946
dorsal ventral axis specification GO:0009950 66 0.943
oocyte microtubule cytoskeleton organization GO:0016325 35 0.940
oocyte axis specification GO:0007309 108 0.938
immune system process GO:0002376 347 0.926
maintenance of gastrointestinal epithelium GO:0030277 3 0.908
positive regulation of humoral immune response GO:0002922 28 0.867
hemocyte differentiation GO:0042386 38 0.864
anterior posterior axis specification GO:0009948 109 0.857
oocyte differentiation GO:0009994 145 0.845
cell division GO:0051301 248 0.827
oocyte construction GO:0007308 112 0.803
positive regulation of gene expression GO:0010628 290 0.800
Human Mouse
regulation of defense response GO:0031347 102 0.796
immune effector process GO:0002252 98 0.783
positive regulation of antimicrobial humoral response GO:0002760 28 0.778
regulation of protein metabolic process GO:0051246 256 0.777
Human Mouse
defense response GO:0006952 300 0.770
production of molecular mediator of immune response GO:0002440 46 0.763
cell maturation GO:0048469 144 0.757
response to external biotic stimulus GO:0043207 293 0.722
regulation of immune response GO:0050776 118 0.699
wing disc morphogenesis GO:0007472 344 0.675
antimicrobial humoral response GO:0019730 99 0.670
regulation of molecular function GO:0065009 217 0.655
Human
antimicrobial peptide production GO:0002775 46 0.647
cytokinesis GO:0000910 90 0.626
single organism cellular localization GO:1902580 180 0.615
Human Mouse Rat
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.580
embryonic development via the syncytial blastoderm GO:0001700 148 0.572
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.546
tissue morphogenesis GO:0048729 297 0.531
regulation of cellular localization GO:0060341 136 0.531
Human Rat
vesicle mediated transport GO:0016192 381 0.519
positive regulation of rna biosynthetic process GO:1902680 266 0.500
Human Mouse
lymph gland development GO:0048542 28 0.489
immune response GO:0006955 246 0.479
regulation of cell cycle GO:0051726 291 0.472
regulation of innate immune response GO:0045088 71 0.471
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.462
Human Mouse
regulation of hemocyte differentiation GO:0045610 22 0.447
anterior posterior axis specification embryo GO:0008595 103 0.444
head involution GO:0008258 35 0.439
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.420
response to biotic stimulus GO:0009607 294 0.420
imaginal disc derived wing morphogenesis GO:0007476 337 0.411
regulation of cellular protein metabolic process GO:0032268 243 0.408
Human
embryonic pattern specification GO:0009880 174 0.392
defense response to bacterium GO:0042742 178 0.384
Mouse Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.381
Human
regulation of response to biotic stimulus GO:0002831 63 0.379
positive regulation of multi organism process GO:0043902 40 0.368
multicellular organismal reproductive behavior GO:0033057 110 0.362
innate immune response GO:0045087 144 0.359
Mouse
negative regulation of defense response GO:0031348 35 0.359
synapse assembly GO:0007416 143 0.359
humoral immune response GO:0006959 117 0.358
morphogenesis of an epithelium GO:0002009 276 0.357
positive regulation of cellular component biogenesis GO:0044089 80 0.350
tube development GO:0035295 244 0.346
maternal determination of anterior posterior axis embryo GO:0008358 74 0.344
endoderm formation GO:0001706 3 0.342
innate immune response in mucosa GO:0002227 2 0.340
regulation of defense response to bacterium GO:1900424 30 0.339
post embryonic appendage morphogenesis GO:0035120 385 0.336
cellular macromolecule localization GO:0070727 220 0.336
Human Mouse Rat
regulation of response to stress GO:0080134 200 0.330
positive regulation of molecular function GO:0044093 136 0.323
catabolic process GO:0009056 409 0.322
regulation of multi organism process GO:0043900 131 0.315
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.308
response to fungus GO:0009620 50 0.304
detection of stimulus GO:0051606 156 0.299
establishment of protein localization GO:0045184 163 0.295
Human Mouse Rat
positive regulation of immune effector process GO:0002699 28 0.282
organic substance catabolic process GO:1901575 308 0.279
positive regulation of response to biotic stimulus GO:0002833 31 0.271
protein localization GO:0008104 284 0.266
Human Mouse Rat
oocyte dorsal ventral axis specification GO:0007310 34 0.257
appendage development GO:0048736 401 0.256
endodermal cell fate commitment GO:0001711 3 0.254
transcription from rna polymerase ii promoter GO:0006366 368 0.252
Human Mouse
defense response to other organism GO:0098542 225 0.251
embryonic axis specification GO:0000578 107 0.244
hindgut morphogenesis GO:0007442 58 0.234
ubiquitin dependent protein catabolic process GO:0006511 78 0.231
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.231
oocyte anterior posterior axis specification GO:0007314 72 0.222
regulation of antimicrobial peptide production GO:0002784 44 0.222
morphogenesis of embryonic epithelium GO:0016331 94 0.216
dorsal ventral pattern formation GO:0009953 133 0.215
taxis GO:0042330 304 0.205
synaptic growth at neuromuscular junction GO:0051124 119 0.201
columnar cuboidal epithelial cell development GO:0002066 249 0.198
positive regulation of antimicrobial peptide production GO:0002225 28 0.197
blastoderm segmentation GO:0007350 159 0.186
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.184
mesenchymal cell differentiation GO:0048762 1 0.183
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.180
positive regulation of defense response GO:0031349 59 0.180
anterior posterior pattern specification GO:0009952 136 0.178
cytoplasmic transport GO:0016482 130 0.177
Human Mouse Rat
body morphogenesis GO:0010171 2 0.176
regulation of hydrolase activity GO:0051336 97 0.175
embryonic morphogenesis GO:0048598 206 0.173
cell junction assembly GO:0034329 42 0.170
cytoplasm organization GO:0007028 64 0.168
establishment of localization in cell GO:0051649 402 0.163
Human Mouse Rat
negative regulation of mitotic cell cycle GO:0045930 109 0.163
developmental maturation GO:0021700 172 0.154
pole plasm assembly GO:0007315 61 0.153
chitin based cuticle development GO:0040003 49 0.153
response to light stimulus GO:0009416 124 0.153
Human
malpighian tubule morphogenesis GO:0007443 44 0.149
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.147
Human Mouse
regulation of cellular catabolic process GO:0031329 157 0.144
melanotic encapsulation of foreign target GO:0035011 30 0.142
toll signaling pathway GO:0008063 25 0.139
antibacterial humoral response GO:0019731 44 0.138
embryo development ending in birth or egg hatching GO:0009792 152 0.138
determination of dorsal ventral asymmetry GO:0048262 3 0.136
chorion containing eggshell formation GO:0007304 105 0.135
regulation of synapse assembly GO:0051963 94 0.135
single fertilization GO:0007338 24 0.129
imaginal disc derived appendage development GO:0048737 399 0.129
pole plasm mrna localization GO:0019094 49 0.129
neurological system process GO:0050877 358 0.128
rna processing GO:0006396 147 0.126
enzyme linked receptor protein signaling pathway GO:0007167 179 0.122
regionalization GO:0003002 416 0.121
positive regulation of developmental growth GO:0048639 62 0.119
instar larval development GO:0002168 55 0.119
fertilization GO:0009566 26 0.119
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.117
Human
determination of bilateral symmetry GO:0009855 13 0.117
cytoskeleton dependent cytokinesis GO:0061640 81 0.116
dorsal closure GO:0007391 79 0.116
antifungal peptide biosynthetic process GO:0002783 5 0.114
organic cyclic compound catabolic process GO:1901361 168 0.113
regulation of cellular component biogenesis GO:0044087 201 0.113
regulation of organ morphogenesis GO:2000027 78 0.111
epithelial tube morphogenesis GO:0060562 88 0.110
tripartite regional subdivision GO:0007351 103 0.110
neuron projection guidance GO:0097485 241 0.110
nuclear division GO:0000280 332 0.109
response to wounding GO:0009611 94 0.109
positive regulation of cellular biosynthetic process GO:0031328 316 0.108
regulation of synapse structure and activity GO:0050803 128 0.107
negative regulation of response to stimulus GO:0048585 258 0.105
Human Mouse Rat
chorion containing eggshell pattern formation GO:0030381 11 0.104
response to radiation GO:0009314 155 0.099
Human
melanization defense response GO:0035006 45 0.097
protein transport GO:0015031 155 0.096
Human Mouse Rat
defense response to gram negative bacterium GO:0050829 94 0.095
Worm
melanin metabolic process GO:0006582 47 0.094
regulation of transport GO:0051049 181 0.094
Human Rat
response to bacterium GO:0009617 198 0.094
Mouse Worm
skin development GO:0043588 65 0.091
embryonic hemopoiesis GO:0035162 26 0.089
protein localization to nucleus GO:0034504 55 0.088
Human Mouse Rat
secretion GO:0046903 109 0.088
regulation of production of molecular mediator of immune response GO:0002700 44 0.088
mitotic cell cycle phase transition GO:0044772 138 0.088
developmental programmed cell death GO:0010623 138 0.087
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.087
Human Mouse
regulation of phosphate metabolic process GO:0019220 210 0.087
regulation of catalytic activity GO:0050790 185 0.087
positive regulation of rna metabolic process GO:0051254 271 0.087
Human Mouse
neuroblast proliferation GO:0007405 74 0.086
regulation of catabolic process GO:0009894 170 0.086
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.085
negative regulation of biosynthetic process GO:0009890 277 0.084
Human Mouse
response to oxygen containing compound GO:1901700 200 0.084
Mouse
regulation of immune effector process GO:0002697 52 0.084
positive regulation of signaling GO:0023056 243 0.082
localization of cell GO:0051674 257 0.081
negative regulation of protein metabolic process GO:0051248 85 0.081
Human Mouse
regulation of pole plasm oskar mrna localization GO:0007317 27 0.081
pronuclear migration GO:0035046 4 0.081
protein complex assembly GO:0006461 200 0.080
cuticle development GO:0042335 86 0.079
regulation of cell differentiation GO:0045595 302 0.078
Human Mouse
intracellular signal transduction GO:0035556 300 0.076
Human Mouse Rat
compound eye development GO:0048749 307 0.074
protein complex biogenesis GO:0070271 201 0.074
chromosome condensation GO:0030261 41 0.073
organelle fission GO:0048285 340 0.073
cellular macromolecule catabolic process GO:0044265 136 0.073
modification dependent macromolecule catabolic process GO:0043632 79 0.072
proteasomal protein catabolic process GO:0010498 59 0.070
peptidyl amino acid modification GO:0018193 105 0.069
cellular catabolic process GO:0044248 372 0.069
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.069
response to starvation GO:0042594 97 0.068
regulation of mitotic cell cycle phase transition GO:1901990 130 0.068
eggshell formation GO:0030703 105 0.067
regulation of cellular amide metabolic process GO:0034248 39 0.067
negative regulation of cellular protein metabolic process GO:0032269 85 0.067
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.066
positive regulation of immune system process GO:0002684 68 0.065
aromatic compound catabolic process GO:0019439 166 0.065
negative regulation of catalytic activity GO:0043086 42 0.065
macromolecular complex assembly GO:0065003 256 0.065
positive regulation of response to stimulus GO:0048584 323 0.064
cellular amino acid metabolic process GO:0006520 61 0.064
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.064
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.064
cell motility GO:0048870 251 0.063
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.062
protein targeting GO:0006605 64 0.062
Human Mouse Rat
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.062
mitotic nuclear division GO:0007067 213 0.061
imaginal disc derived appendage morphogenesis GO:0035114 395 0.061
protein catabolic process GO:0030163 101 0.061
tube morphogenesis GO:0035239 191 0.060
terminal region determination GO:0007362 25 0.060
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.060
post embryonic hemopoiesis GO:0035166 17 0.060
macromolecule catabolic process GO:0009057 161 0.059
synapse organization GO:0050808 196 0.059
regulation of cell cycle phase transition GO:1901987 130 0.058
negative regulation of molecular function GO:0044092 51 0.057
Human
molting cycle chitin based cuticle GO:0007591 56 0.057
translation GO:0006412 69 0.056
Human
endodermal cell differentiation GO:0035987 3 0.056
positive regulation of cellular protein metabolic process GO:0032270 118 0.056
Human
cellular response to chemical stimulus GO:0070887 199 0.056
Mouse
positive regulation of mitotic cell cycle GO:0045931 34 0.056
positive regulation of antibacterial peptide production GO:0002803 20 0.056
positive regulation of signal transduction GO:0009967 223 0.055
ovarian follicle cell development GO:0030707 248 0.055
positive regulation of cellular component organization GO:0051130 156 0.055
cellular response to organic substance GO:0071310 132 0.054
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.054
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.054
negative regulation of rna metabolic process GO:0051253 251 0.054
Human
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.053
intracellular mrna localization GO:0008298 66 0.053
axon development GO:0061564 297 0.053
mitotic spindle organization GO:0007052 220 0.051
stem cell proliferation GO:0072089 88 0.050
response to organic substance GO:0010033 284 0.050
Mouse
apical junction assembly GO:0043297 32 0.050
respiratory system development GO:0060541 213 0.049
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.048
negative regulation of gene expression GO:0010629 387 0.048
Human
protein targeting to nucleus GO:0044744 51 0.048
Human Mouse Rat
regulation of antimicrobial humoral response GO:0002759 50 0.048
cellular ketone metabolic process GO:0042180 24 0.047
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.047
regulation of protein complex assembly GO:0043254 42 0.047
protein import into nucleus GO:0006606 51 0.047
Human Mouse Rat
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.046
regulation of cellular amine metabolic process GO:0033238 3 0.046
cellular component assembly involved in morphogenesis GO:0010927 151 0.046
phagocytosis GO:0006909 215 0.044
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.044
cell junction organization GO:0034330 57 0.044
reproductive structure development GO:0048608 74 0.044
regulation of mrna 3 end processing GO:0031440 7 0.044
jnk cascade GO:0007254 50 0.043
regulation of cell cycle process GO:0010564 181 0.043
positive regulation of transport GO:0051050 92 0.043
Human
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.043
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.043
Human Mouse
photoreceptor cell differentiation GO:0046530 170 0.042
response to other organism GO:0051707 293 0.042
epithelial cell differentiation GO:0030855 322 0.042
positive regulation of biosynthetic process GO:0009891 316 0.041
regulation of synapse organization GO:0050807 110 0.041
epidermal growth factor receptor signaling pathway GO:0007173 58 0.041
eye morphogenesis GO:0048592 260 0.041
oxoacid metabolic process GO:0043436 103 0.041
axon guidance GO:0007411 233 0.040
proteolysis GO:0006508 192 0.040
germ band shortening GO:0007390 19 0.040
cellular response to abiotic stimulus GO:0071214 58 0.040
cellular response to peptide GO:1901653 28 0.039
regulation of toll signaling pathway GO:0008592 17 0.039
positive regulation of multicellular organismal process GO:0051240 143 0.039
Mouse
actin cytoskeleton organization GO:0030036 206 0.039
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.039
Human Rat
antibacterial peptide biosynthetic process GO:0002780 22 0.039
response to uv GO:0009411 24 0.038
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.038
Human
regulation of notch signaling pathway GO:0008593 100 0.038
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.038
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.038
Human Mouse
actin filament based process GO:0030029 220 0.038
larval development GO:0002164 104 0.038
stress activated protein kinase signaling cascade GO:0031098 55 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.038
pattern recognition receptor signaling pathway GO:0002221 2 0.038
Mouse
cell cycle phase transition GO:0044770 140 0.037
response to nutrient levels GO:0031667 114 0.037
regulation of mitotic cell cycle GO:0007346 190 0.037
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.037
regulation of multicellular organismal development GO:2000026 414 0.037
Mouse
response to organonitrogen compound GO:0010243 75 0.037
Mouse
single organism catabolic process GO:0044712 228 0.037
stem cell differentiation GO:0048863 117 0.037
regulation of protein kinase activity GO:0045859 51 0.036
heterocycle catabolic process GO:0046700 166 0.035
regulation of jnk cascade GO:0046328 40 0.035
activation of innate immune response GO:0002218 4 0.035
Mouse
regulation of response to wounding GO:1903034 19 0.035
rna localization GO:0006403 115 0.035
positive regulation of cell motility GO:2000147 3 0.035
regulation of immune system process GO:0002682 176 0.034
erbb signaling pathway GO:0038127 58 0.034
regulation of protein polymerization GO:0032271 28 0.034
organelle assembly GO:0070925 198 0.034
stem cell fate commitment GO:0048865 25 0.033
intracellular protein transport GO:0006886 104 0.033
Human Mouse Rat
hematopoietic or lymphoid organ development GO:0048534 57 0.033
Mouse
endocytosis GO:0006897 310 0.033
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.032
regulation of response to external stimulus GO:0032101 115 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.032
photoreceptor cell development GO:0042461 96 0.032
chemotaxis GO:0006935 249 0.032
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.031
cell cell junction assembly GO:0007043 38 0.031
eye photoreceptor cell differentiation GO:0001754 145 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.031
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.030
Mouse
digestive tract morphogenesis GO:0048546 127 0.030
heart development GO:0007507 82 0.030
single organism nuclear import GO:1902593 51 0.030
Human Mouse Rat
positive regulation of nervous system development GO:0051962 69 0.030
positive regulation of immune response GO:0050778 63 0.030
regulation of intracellular signal transduction GO:1902531 236 0.029
Human Rat
nuclear transcribed mrna catabolic process GO:0000956 24 0.029
larval lymph gland hemopoiesis GO:0035167 17 0.029
regulation of translation GO:0006417 56 0.029
Human
regulation of map kinase activity GO:0043405 17 0.029
maintenance of protein location in cell GO:0032507 26 0.029
Human Rat
protein localization to organelle GO:0033365 82 0.029
Human Mouse Rat
regulation of nervous system development GO:0051960 248 0.029
detection of external stimulus GO:0009581 66 0.029
regulation of stress activated mapk cascade GO:0032872 41 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
single organism intracellular transport GO:1902582 207 0.028
Human Mouse Rat
positive regulation of r7 cell differentiation GO:0045678 7 0.028
immune system development GO:0002520 57 0.028
Mouse
regulation of proteolysis GO:0030162 87 0.028
positive regulation of lipid biosynthetic process GO:0046889 3 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
Human Mouse
dephosphorylation GO:0016311 51 0.028
single organism behavior GO:0044708 391 0.028
regulation of protein transport GO:0051223 57 0.028
Human Rat
mitotic cell cycle checkpoint GO:0007093 88 0.027
dorsal closure spreading of leading edge cells GO:0007395 4 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
dna metabolic process GO:0006259 227 0.027
hemopoiesis GO:0030097 46 0.027
Mouse
stress activated mapk cascade GO:0051403 52 0.027
dendrite morphogenesis GO:0048813 199 0.026
regulation of cell cell adhesion GO:0022407 21 0.026
compound eye morphogenesis GO:0001745 249 0.026
long term memory GO:0007616 62 0.026
antibacterial peptide production GO:0002778 22 0.026
positive regulation of protein complex assembly GO:0031334 22 0.026
regulation of intracellular transport GO:0032386 64 0.026
Human Rat
male gamete generation GO:0048232 201 0.025
mushroom body development GO:0016319 70 0.025
positive regulation of protein metabolic process GO:0051247 128 0.025
Human Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.025
ameboidal type cell migration GO:0001667 151 0.025
positive regulation of phosphate metabolic process GO:0045937 139 0.025
cellular protein catabolic process GO:0044257 83 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.025
organelle localization GO:0051640 148 0.025
cellular protein localization GO:0034613 160 0.025
Human Mouse Rat
regulation of cellular component movement GO:0051270 42 0.024
positive regulation of phosphorus metabolic process GO:0010562 139 0.024
positive regulation of catabolic process GO:0009896 105 0.024
wound healing GO:0042060 75 0.024
peptide metabolic process GO:0006518 80 0.024
immune response activating signal transduction GO:0002757 2 0.024
Mouse
establishment of protein localization to organelle GO:0072594 62 0.024
Human Mouse Rat
neural precursor cell proliferation GO:0061351 75 0.024
receptor mediated endocytosis GO:0006898 21 0.024
neuronal action potential GO:0019228 10 0.024
cellular protein modification process GO:0006464 438 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.024
axonogenesis GO:0007409 290 0.023
single organismal cell cell adhesion GO:0016337 45 0.023
organic substance transport GO:0071702 257 0.023
Human Mouse Rat
positive regulation of synapse assembly GO:0051965 29 0.023
pole plasm rna localization GO:0007316 52 0.022
mesoderm development GO:0007498 78 0.022
maintenance of apical basal cell polarity GO:0035090 8 0.022
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.022
tissue migration GO:0090130 155 0.022
protein maturation GO:0051604 71 0.022
cellular protein complex assembly GO:0043623 71 0.022
peptidyl tyrosine phosphorylation GO:0018108 24 0.022
maintenance of protein location GO:0045185 28 0.022
Human Rat
negative regulation of cell cycle GO:0045786 116 0.022
locomotory behavior GO:0007626 176 0.022
negative regulation of signal transduction GO:0009968 206 0.021
Human Mouse Rat
malpighian tubule development GO:0072002 64 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
regulation of histone deacetylation GO:0031063 2 0.021
regulation of protein modification process GO:0031399 112 0.020
epithelial cell migration GO:0010631 148 0.020
positive regulation of secretion GO:0051047 22 0.020
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.020
mesenchymal cell development GO:0014031 1 0.020
amide biosynthetic process GO:0043604 42 0.020
determination of adult lifespan GO:0008340 137 0.020
larval lymph gland hemocyte differentiation GO:0035168 11 0.020
positive regulation of secretion by cell GO:1903532 20 0.020
modification dependent protein catabolic process GO:0019941 78 0.020
mrna processing GO:0006397 104 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
guanosine containing compound catabolic process GO:1901069 74 0.019
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.019
negative regulation of catabolic process GO:0009895 36 0.019
appendage morphogenesis GO:0035107 397 0.019
regulation of ion transport GO:0043269 39 0.019
germarium derived egg chamber formation GO:0007293 101 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.019
detection of abiotic stimulus GO:0009582 66 0.019
response to transforming growth factor beta GO:0071559 18 0.019
protein processing GO:0016485 68 0.019
regulation of cellular component size GO:0032535 98 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.019
regulation of proteasomal protein catabolic process GO:0061136 39 0.019
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.019
carbohydrate metabolic process GO:0005975 82 0.018
meiotic cell cycle GO:0051321 171 0.018
spindle organization GO:0007051 253 0.018
eye development GO:0001654 323 0.018
muscle cell fate commitment GO:0042693 14 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
Human
regulation of antibacterial peptide production GO:0002786 22 0.017
cell cell junction organization GO:0045216 55 0.017
imaginal disc derived wing vein specification GO:0007474 48 0.017
retinal cell programmed cell death GO:0046666 25 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
sex differentiation GO:0007548 81 0.017
eggshell chorion assembly GO:0007306 66 0.017
neuroblast division GO:0055057 35 0.017
pole plasm protein localization GO:0007318 10 0.017
negative regulation of innate immune response GO:0045824 30 0.017
sensory organ morphogenesis GO:0090596 260 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
Human Mouse
biological adhesion GO:0022610 138 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.016
Human Mouse
regulation of protein catabolic process GO:0042176 55 0.016
positive regulation of cell cycle GO:0045787 43 0.016
cellular response to lipid GO:0071396 20 0.016
Mouse
compound eye retinal cell programmed cell death GO:0046667 23 0.016
exocrine system development GO:0035272 162 0.016
positive regulation of cell proliferation GO:0008284 47 0.016
segmentation GO:0035282 207 0.015
regulation of cell junction assembly GO:1901888 2 0.015
regulation of synaptic transmission GO:0050804 69 0.015
positive regulation of defense response to bacterium GO:1900426 23 0.015
gland development GO:0048732 191 0.015
neuromuscular junction development GO:0007528 149 0.015
embryonic foregut morphogenesis GO:0048617 3 0.015
antifungal peptide production GO:0002781 7 0.015
tissue homeostasis GO:0001894 36 0.015
cellular response to radiation GO:0071478 52 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
Human Mouse Rat
meiotic cytokinesis GO:0033206 33 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.014
dorsal appendage formation GO:0046843 47 0.014
peptidyl threonine modification GO:0018210 3 0.014
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.014
initiation of dorsal closure GO:0007392 12 0.014
positive regulation of cell communication GO:0010647 250 0.014
negative regulation of proteolysis GO:0045861 31 0.014
adult behavior GO:0030534 137 0.014
hormone metabolic process GO:0042445 33 0.014
ectodermal digestive tract morphogenesis GO:0048567 7 0.014
regulation of embryonic development GO:0045995 68 0.014
single organism membrane organization GO:0044802 93 0.014
negative regulation of immune response GO:0050777 39 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.013
golgi organization GO:0007030 66 0.013

cact disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
benign neoplasm DOID:0060072 0 0.015