Drosophila melanogaster

70 known processes

Nap1 (Dmel_CG5330)

Nucleosome assembly protein 1

(Aliases: dNap,dNap1,NAP1,Nap-1,dNAP-1,p56/dCAF-4,NAP-1,Dmel\CG5330,dNAP1,CG5330)

Nap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribosomal large subunit biogenesis GO:0042273 1 0.765
negative regulation of rna biosynthetic process GO:1902679 240 0.700
chromatin organization GO:0006325 207 0.420
nuclear division GO:0000280 332 0.412
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.375
dna metabolic process GO:0006259 227 0.367
response to abiotic stimulus GO:0009628 341 0.360
negative regulation of cellular biosynthetic process GO:0031327 277 0.334
meiotic nuclear division GO:0007126 151 0.332
chromosome organization GO:0051276 360 0.299
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.266
spindle organization GO:0007051 253 0.225
gene silencing GO:0016458 138 0.218
Worm
ribonucleoprotein complex subunit organization GO:0071826 28 0.218
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.218
translation GO:0006412 69 0.205
organelle fission GO:0048285 340 0.204
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.198
cellular macromolecular complex assembly GO:0034622 153 0.187
negative regulation of gene expression GO:0010629 387 0.182
Worm
negative regulation of transcription dna templated GO:0045892 237 0.178
meiotic cell cycle GO:0051321 171 0.178
rrna processing GO:0006364 3 0.166
negative regulation of cellular metabolic process GO:0031324 382 0.163
chromatin modification GO:0016568 147 0.162
negative regulation of biosynthetic process GO:0009890 277 0.153
mitotic spindle organization GO:0007052 220 0.150
positive regulation of cellular biosynthetic process GO:0031328 316 0.145
lipid storage GO:0019915 38 0.129
programmed cell death GO:0012501 257 0.126
negative regulation of nucleic acid templated transcription GO:1903507 240 0.124
negative regulation of gene expression epigenetic GO:0045814 77 0.119
regulation of protein metabolic process GO:0051246 256 0.112
ribonucleoprotein complex biogenesis GO:0022613 31 0.112
response to temperature stimulus GO:0009266 106 0.111
dendrite development GO:0016358 204 0.111
regulation of gene expression epigenetic GO:0040029 128 0.105
Worm
death GO:0016265 284 0.105
apoptotic process GO:0006915 159 0.091
ribonucleoprotein complex assembly GO:0022618 23 0.090
regulation of cellular protein metabolic process GO:0032268 243 0.085
chromatin silencing GO:0006342 76 0.084
ribosome biogenesis GO:0042254 8 0.082
histone modification GO:0016570 106 0.082
establishment of localization in cell GO:0051649 402 0.080
embryo development ending in birth or egg hatching GO:0009792 152 0.080
Worm
dendrite morphogenesis GO:0048813 199 0.079
response to external biotic stimulus GO:0043207 293 0.077
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.075
protein modification process GO:0036211 438 0.074
sex differentiation GO:0007548 81 0.074
Worm
cellular catabolic process GO:0044248 372 0.072
endocytosis GO:0006897 310 0.063
regionalization GO:0003002 416 0.063
cellular response to dna damage stimulus GO:0006974 223 0.062
mitotic dna integrity checkpoint GO:0044774 75 0.061
translational initiation GO:0006413 11 0.061
oocyte axis specification GO:0007309 108 0.059
growth GO:0040007 359 0.059
negative regulation of rna metabolic process GO:0051253 251 0.058
protein modification by small protein conjugation GO:0032446 79 0.057
single organism biosynthetic process GO:0044711 206 0.055
macromolecular complex assembly GO:0065003 256 0.054
reproductive system development GO:0061458 74 0.052
Worm
mitotic dna damage checkpoint GO:0044773 74 0.051
regulation of translation GO:0006417 56 0.050
cell death GO:0008219 279 0.050
cellular protein modification process GO:0006464 438 0.049
dna damage checkpoint GO:0000077 78 0.047
developmental maturation GO:0021700 172 0.045
positive regulation of transcription dna templated GO:0045893 266 0.045
cellular macromolecule localization GO:0070727 220 0.045
ncrna metabolic process GO:0034660 43 0.042
spermatid differentiation GO:0048515 114 0.042
single organism behavior GO:0044708 391 0.041
positive regulation of gene expression GO:0010628 290 0.041
cellular macromolecule catabolic process GO:0044265 136 0.040
meiotic cell cycle process GO:1903046 132 0.038
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.038
gonad development GO:0008406 50 0.037
Worm
maintenance of location GO:0051235 73 0.037
reproductive structure development GO:0048608 74 0.037
Worm
macromolecule catabolic process GO:0009057 161 0.036
mitotic nuclear division GO:0007067 213 0.036
catabolic process GO:0009056 409 0.035
body morphogenesis GO:0010171 2 0.035
Worm
oocyte construction GO:0007308 112 0.035
regulation of growth GO:0040008 233 0.034
positive regulation of peptidase activity GO:0010952 29 0.034
posttranscriptional gene silencing by rna GO:0035194 45 0.033
Worm
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
oocyte differentiation GO:0009994 145 0.033
multicellular organism growth GO:0035264 46 0.033
lateral inhibition GO:0046331 206 0.033
dorsal ventral pattern formation GO:0009953 133 0.032
protein catabolic process GO:0030163 101 0.032
centrosome organization GO:0051297 163 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.031
establishment of organelle localization GO:0051656 122 0.031
protein dna complex subunit organization GO:0071824 86 0.031
multi organism behavior GO:0051705 175 0.031
multicellular organismal reproductive behavior GO:0033057 110 0.030
regulation of cell differentiation GO:0045595 302 0.030
axis specification GO:0009798 167 0.030
rna interference GO:0016246 27 0.029
Worm
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
posttranscriptional regulation of gene expression GO:0010608 145 0.027
Worm
ncrna processing GO:0034470 30 0.027
gene silencing by rna GO:0031047 57 0.026
Worm
small molecule metabolic process GO:0044281 305 0.026
negative regulation of cell communication GO:0010648 223 0.026
genitalia development GO:0048806 26 0.025
Worm
positive regulation of cellular protein metabolic process GO:0032270 118 0.024
cytoplasmic transport GO:0016482 130 0.023
chromosome segregation GO:0007059 157 0.023
regulation of developmental growth GO:0048638 174 0.023
regulation of cell death GO:0010941 173 0.023
positive regulation of rna biosynthetic process GO:1902680 266 0.022
covalent chromatin modification GO:0016569 106 0.022
organic substance catabolic process GO:1901575 308 0.022
protein complex biogenesis GO:0070271 201 0.022
single organism intracellular transport GO:1902582 207 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.022
protein acetylation GO:0006473 39 0.021
cellular protein localization GO:0034613 160 0.021
detection of stimulus GO:0051606 156 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
negative regulation of cell death GO:0060548 81 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
spindle assembly involved in mitosis GO:0090307 50 0.019
aromatic compound catabolic process GO:0019439 166 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
regulation of apoptotic process GO:0042981 130 0.019
positive regulation of endopeptidase activity GO:0010950 26 0.019
mitotic g2 dna damage checkpoint GO:0007095 69 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
cell maturation GO:0048469 144 0.019
amine metabolic process GO:0009308 12 0.019
positive regulation of proteolysis GO:0045862 52 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.018
lipid localization GO:0010876 54 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
g2 dna damage checkpoint GO:0031572 69 0.018
negative regulation of molecular function GO:0044092 51 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
dna replication GO:0006260 48 0.018
dna integrity checkpoint GO:0031570 81 0.017
organonitrogen compound metabolic process GO:1901564 318 0.017
regulation of organelle organization GO:0033043 196 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
taxis GO:0042330 304 0.017
developmental growth GO:0048589 280 0.017
protein localization GO:0008104 284 0.017
spermatogenesis GO:0007283 200 0.016
nucleosome assembly GO:0006334 35 0.016
protein acylation GO:0043543 42 0.016
regulation of cell cycle GO:0051726 291 0.016
positive regulation of developmental growth GO:0048639 62 0.016
negative regulation of developmental process GO:0051093 201 0.015
oocyte development GO:0048599 124 0.015
organelle assembly GO:0070925 198 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
regulation of dna metabolic process GO:0051052 34 0.014
male meiosis GO:0007140 52 0.014
cell cycle dna replication GO:0044786 23 0.014
segmentation GO:0035282 207 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
regulation of cell cycle process GO:0010564 181 0.014
positive regulation of developmental process GO:0051094 143 0.014
regulation of phosphatase activity GO:0010921 3 0.014
posttranscriptional gene silencing GO:0016441 46 0.014
Worm
sister chromatid segregation GO:0000819 92 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
rna processing GO:0006396 147 0.014
cellular response to nitrogen compound GO:1901699 51 0.013
regulation of multicellular organism growth GO:0040014 40 0.013
organelle localization GO:0051640 148 0.013
determination of adult lifespan GO:0008340 137 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
regulation of meiosis GO:0040020 3 0.013
tripartite regional subdivision GO:0007351 103 0.013
cell division GO:0051301 248 0.013
nucleosome organization GO:0034728 59 0.013
regulation of programmed cell death GO:0043067 152 0.012
histolysis GO:0007559 102 0.012
muscle organ development GO:0007517 127 0.012
microtubule organizing center organization GO:0031023 168 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
larval development GO:0002164 104 0.012
Worm
male gamete generation GO:0048232 201 0.012
dna repair GO:0006281 54 0.012
response to other organism GO:0051707 293 0.012
Zebrafish
sensory organ morphogenesis GO:0090596 260 0.012
response to light stimulus GO:0009416 124 0.012
gliogenesis GO:0042063 80 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.011
nucleoside biosynthetic process GO:0009163 3 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
peptidyl lysine acetylation GO:0018394 39 0.011
cell aging GO:0007569 2 0.011
cell cycle phase transition GO:0044770 140 0.011
gland development GO:0048732 191 0.011
salivary gland histolysis GO:0035070 88 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
spermatid development GO:0007286 98 0.011
reproductive behavior GO:0019098 122 0.011
organophosphate metabolic process GO:0019637 195 0.011
oxoacid metabolic process GO:0043436 103 0.011
immune response GO:0006955 246 0.011
dorsal ventral axis specification GO:0009950 66 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
response to bacterium GO:0009617 198 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
muscle structure development GO:0061061 224 0.010
single organism cellular localization GO:1902580 180 0.010

Nap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
synucleinopathy DOID:0050890 0 0.022
central nervous system disease DOID:331 0 0.022
neurodegenerative disease DOID:1289 0 0.022
nervous system disease DOID:863 0 0.022